ATE521337T1 - Verfahren zur herstellung einer pharmazeutischen co-kristall-zusammensetzung - Google Patents
Verfahren zur herstellung einer pharmazeutischen co-kristall-zusammensetzungInfo
- Publication number
- ATE521337T1 ATE521337T1 AT08779037T AT08779037T ATE521337T1 AT E521337 T1 ATE521337 T1 AT E521337T1 AT 08779037 T AT08779037 T AT 08779037T AT 08779037 T AT08779037 T AT 08779037T AT E521337 T1 ATE521337 T1 AT E521337T1
- Authority
- AT
- Austria
- Prior art keywords
- pharmaceutically active
- active component
- builder
- solid particles
- supercritical
- Prior art date
Links
- 239000013078 crystal Substances 0.000 title abstract 8
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 6
- 239000007787 solid Substances 0.000 abstract 6
- 238000000034 method Methods 0.000 abstract 3
- 238000002288 cocrystallisation Methods 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 230000001131 transforming effect Effects 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J3/00—Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matter; Apparatus therefor
- B01J3/008—Processes carried out under supercritical conditions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07112692 | 2007-07-18 | ||
| PCT/NL2008/050490 WO2009011584A2 (en) | 2007-07-18 | 2008-07-17 | A method of preparing a pharmaceutical co-crystal composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE521337T1 true ATE521337T1 (de) | 2011-09-15 |
Family
ID=38626724
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08779037T ATE521337T1 (de) | 2007-07-18 | 2008-07-17 | Verfahren zur herstellung einer pharmazeutischen co-kristall-zusammensetzung |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20100184744A1 (de) |
| EP (1) | EP2170284B1 (de) |
| AT (1) | ATE521337T1 (de) |
| WO (1) | WO2009011584A2 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201222287D0 (en) | 2012-12-11 | 2013-01-23 | Ct For Process Innovation Ltd | Methods for making active crystalline materials |
| PT107166B (pt) * | 2013-09-16 | 2018-12-28 | Hovione Farm S A | Síntese e engenharia de partículas de cocristais |
| GB2600463A (en) * | 2020-10-30 | 2022-05-04 | Cubic Pharmaceuticals Ltd | Process of preparing pharmaceutical solids |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4041563A1 (de) * | 1990-12-22 | 1992-06-25 | Sanol Arznei Schwarz Gmbh | Verfahren zur herstellung wirkstoffhaltiger mikropartikel aus hydrolytisch abbaubaren polymeren |
| DK1263413T3 (da) * | 2000-03-09 | 2006-09-11 | Univ Ohio State Res Found | Fremgangsmåde til fremstilling af faste dispersioner |
| US20070099237A1 (en) * | 2005-10-31 | 2007-05-03 | The Regents Of The University Of Michigan | Reaction co-crystallization of molecular complexes or co-crystals |
-
2008
- 2008-07-17 US US12/669,779 patent/US20100184744A1/en not_active Abandoned
- 2008-07-17 AT AT08779037T patent/ATE521337T1/de not_active IP Right Cessation
- 2008-07-17 WO PCT/NL2008/050490 patent/WO2009011584A2/en not_active Ceased
- 2008-07-17 EP EP08779037A patent/EP2170284B1/de not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| WO2009011584A3 (en) | 2009-07-16 |
| EP2170284A2 (de) | 2010-04-07 |
| EP2170284B1 (de) | 2011-08-24 |
| WO2009011584A2 (en) | 2009-01-22 |
| US20100184744A1 (en) | 2010-07-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |