ATE521591T1 - 11c-markierte benzyl-lactam-verbindungen und deren verwendung als bildgebungsmittel - Google Patents
11c-markierte benzyl-lactam-verbindungen und deren verwendung als bildgebungsmittelInfo
- Publication number
- ATE521591T1 ATE521591T1 AT06701554T AT06701554T ATE521591T1 AT E521591 T1 ATE521591 T1 AT E521591T1 AT 06701554 T AT06701554 T AT 06701554T AT 06701554 T AT06701554 T AT 06701554T AT E521591 T1 ATE521591 T1 AT E521591T1
- Authority
- AT
- Austria
- Prior art keywords
- labled
- benzyl
- imaging agents
- lactam compounds
- compounds
- Prior art date
Links
- 239000012216 imaging agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 1
- 238000002600 positron emission tomography Methods 0.000 abstract 1
- 229940121896 radiopharmaceutical Drugs 0.000 abstract 1
- 239000012217 radiopharmaceutical Substances 0.000 abstract 1
- 230000002799 radiopharmaceutical effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64345305P | 2005-01-13 | 2005-01-13 | |
| PCT/IB2006/000028 WO2006075226A1 (en) | 2005-01-13 | 2006-01-11 | 11c-labeled benzyl-lactam compounds and their use as imaging agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE521591T1 true ATE521591T1 (de) | 2011-09-15 |
Family
ID=36061190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06701554T ATE521591T1 (de) | 2005-01-13 | 2006-01-11 | 11c-markierte benzyl-lactam-verbindungen und deren verwendung als bildgebungsmittel |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8012969B2 (de) |
| EP (1) | EP1836164B1 (de) |
| AT (1) | ATE521591T1 (de) |
| ES (1) | ES2371927T3 (de) |
| WO (1) | WO2006075226A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007026224A2 (en) * | 2005-08-31 | 2007-03-08 | Pfizer Products Inc. | 5-ht1b antagonist composition for depression, anxiety and cognition |
| PT2637704E (pt) | 2010-11-10 | 2015-07-21 | Lundbeck & Co As H | Ligandos baseados em fenilimidazole radiomarcado |
| CN110590634A (zh) * | 2019-09-29 | 2019-12-20 | 迈奇化学股份有限公司 | 一种1-乙酰基-2-吡咯烷酮的生产方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1128788C (zh) * | 1996-03-29 | 2003-11-26 | 辉瑞大药厂 | 苄基(亚苄基)－内酰胺衍生物,它们的制备以及作为5－ht1a和/或5－ht1d受体的选择性拮抗剂(激动剂)的用途 |
| DE60013751T2 (de) * | 1999-12-29 | 2005-09-29 | Pfizer Products Inc., Groton | Optisch aktive 3-((2-piperazinyl-phenyl)methyl)-1-(4-(trifluoromethyl)-phenyl)-2-pyrrolidinone als selektive 5-HT1D Rezeptor Antagonisten |
| ATE533745T1 (de) * | 2004-03-17 | 2011-12-15 | Pfizer Prod Inc | Neue benzyl(iden)-lactam-derivate |
-
2006
- 2006-01-11 AT AT06701554T patent/ATE521591T1/de not_active IP Right Cessation
- 2006-01-11 EP EP06701554A patent/EP1836164B1/de not_active Expired - Lifetime
- 2006-01-11 US US11/813,779 patent/US8012969B2/en not_active Expired - Fee Related
- 2006-01-11 WO PCT/IB2006/000028 patent/WO2006075226A1/en not_active Ceased
- 2006-01-11 ES ES06701554T patent/ES2371927T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20080206137A1 (en) | 2008-08-28 |
| US8012969B2 (en) | 2011-09-06 |
| ES2371927T3 (es) | 2012-01-11 |
| WO2006075226A1 (en) | 2006-07-20 |
| EP1836164A1 (de) | 2007-09-26 |
| EP1836164B1 (de) | 2011-08-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |