ATE521604T1 - N-substituierte benzimidazolyl-c-kit-inhibitoren und kombinatorische benzimidazolbibliothek - Google Patents
N-substituierte benzimidazolyl-c-kit-inhibitoren und kombinatorische benzimidazolbibliothekInfo
- Publication number
- ATE521604T1 ATE521604T1 AT05852400T AT05852400T ATE521604T1 AT E521604 T1 ATE521604 T1 AT E521604T1 AT 05852400 T AT05852400 T AT 05852400T AT 05852400 T AT05852400 T AT 05852400T AT E521604 T1 ATE521604 T1 AT E521604T1
- Authority
- AT
- Austria
- Prior art keywords
- combinatory
- benzimidazole
- library
- kit inhibitors
- substituted benzimidazolyl
- Prior art date
Links
- HYZJCKYKOHLVJF-UHFFFAOYSA-N 1H-benzimidazole Chemical compound C1=CC=C2NC=NC2=C1 HYZJCKYKOHLVJF-UHFFFAOYSA-N 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/11—Compounds covalently bound to a solid support
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63243204P | 2004-12-01 | 2004-12-01 | |
| PCT/US2005/043114 WO2006060381A2 (en) | 2004-12-01 | 2005-11-30 | N-substituted benzimidazolyl c-kit inhibitors and combinatorial benzimidazole library |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE521604T1 true ATE521604T1 (de) | 2011-09-15 |
Family
ID=36128376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05852400T ATE521604T1 (de) | 2004-12-01 | 2005-11-30 | N-substituierte benzimidazolyl-c-kit-inhibitoren und kombinatorische benzimidazolbibliothek |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7419995B2 (de) |
| EP (1) | EP1831206B1 (de) |
| JP (1) | JP2008521903A (de) |
| KR (1) | KR20070086865A (de) |
| CN (1) | CN101193867A (de) |
| AR (1) | AR052419A1 (de) |
| AT (1) | ATE521604T1 (de) |
| AU (1) | AU2005312028A1 (de) |
| BR (1) | BRPI0518794A2 (de) |
| CA (1) | CA2589770A1 (de) |
| TW (1) | TW200633704A (de) |
| WO (1) | WO2006060381A2 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7442709B2 (en) * | 2003-08-21 | 2008-10-28 | Osi Pharmaceuticals, Inc. | N3-substituted imidazopyridine c-Kit inhibitors |
| CA2604516A1 (en) | 2005-04-13 | 2006-10-19 | Neurosearch A/S | Benzimidazole derivatives and their use for modulating the gabaa receptor complex |
| EP1874758A1 (de) * | 2005-04-19 | 2008-01-09 | Neurosearch A/S | Benzimidazol-derivate und ihre verwendung zur modulierung des gabaa-rezeptor-komplexes |
| US7923464B2 (en) * | 2005-12-05 | 2011-04-12 | Neurosearch A/S | Benzimidazole derivatives and their use for modulating the GABAA receptor complex |
| TWI391381B (zh) | 2006-03-24 | 2013-04-01 | Neurosearch As | 新穎的苯并咪唑衍生物、含有其之醫藥組成物、及其於製造藥物之用途 |
| CN101679408B (zh) * | 2006-12-22 | 2016-04-27 | Astex治疗学有限公司 | 作为fgfr抑制剂的双环杂环化合物 |
| JP5442449B2 (ja) * | 2006-12-22 | 2014-03-12 | アステックス、セラピューティックス、リミテッド | 新規化合物 |
| GB0720041D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New Compounds |
| GB0720038D0 (en) | 2007-10-12 | 2007-11-21 | Astex Therapeutics Ltd | New compounds |
| GB0810902D0 (en) | 2008-06-13 | 2008-07-23 | Astex Therapeutics Ltd | New compounds |
| GB0906472D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| GB0906470D0 (en) | 2009-04-15 | 2009-05-20 | Astex Therapeutics Ltd | New compounds |
| US20110030037A1 (en) * | 2009-07-07 | 2011-02-03 | Vadim Olshansky | Zone migration in network access |
| WO2012131501A1 (en) * | 2011-03-28 | 2012-10-04 | Glenmark Pharmaceuticals S.A. | Substituted benzimidazole compounds as cot kinase inhibitors |
| UA111382C2 (uk) * | 2011-10-10 | 2016-04-25 | Оріон Корпорейшн | Інгібітори протеїнкінази |
| CN103254134B (zh) * | 2012-06-29 | 2015-09-02 | 苏州大学 | 一种多取代咪唑的合成方法 |
| JP2016520532A (ja) | 2013-03-15 | 2016-07-14 | ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ | ベンゾイミダゾール誘導体およびその使用 |
| CN103254136B (zh) * | 2013-05-30 | 2015-03-25 | 苏州大学 | 一种制备四[4-(1-咪唑基)苯基]甲烷的方法 |
| CN103497179B (zh) * | 2013-09-26 | 2015-03-25 | 郑州大学 | 含苯并咪唑结构单元的嘧啶衍生物及其制备方法和用途 |
| CR20180109A (es) * | 2015-07-20 | 2018-05-03 | Genzyme Corp | Inhibidores de receptor del factor estimulador de colonias 1 (csf-1r) |
| US11117883B2 (en) * | 2016-12-15 | 2021-09-14 | Ariad Pharmaceuticals, Inc. | Benzimidazole compounds as c-Kit inhibitors |
| CN108754141B (zh) * | 2018-08-22 | 2020-12-08 | 中国科学院上海有机化学研究所 | 一种萃取有机相及其应用 |
| CA3129665A1 (en) | 2019-03-21 | 2020-09-24 | Onxeo | A dbait molecule in combination with kinase inhibitor for the treatment of cancer |
| KR20220098759A (ko) | 2019-11-08 | 2022-07-12 | 인쎄름 (엥스띠뛰 나씨오날 드 라 쌍떼 에 드 라 흐쉐르슈 메디깔) | 키나제 억제제에 대해 내성을 획득한 암의 치료 방법 |
| WO2021148581A1 (en) | 2020-01-22 | 2021-07-29 | Onxeo | Novel dbait molecule and its use |
| US11530216B2 (en) | 2020-12-23 | 2022-12-20 | Genzyme Corporation | Deuterated colony stimulating factor-1 receptor (CSF-1R) inhibitors |
Family Cites Families (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6087380A (en) | 1949-11-24 | 2000-07-11 | Boehringer Ingelheim Pharma Kg | Disubstituted bicyclic heterocycles, the preparations and the use thereof as pharmaceutical compositions |
| BE788751A (fr) | 1971-09-13 | 1973-01-02 | Teijin Ltd | Membranes polymeres permselectives |
| GB8610980D0 (en) | 1986-05-06 | 1986-06-11 | Ici America Inc | Heterocyclic fused tricyclic compounds |
| US5814651A (en) | 1992-12-02 | 1998-09-29 | Pfizer Inc. | Catechol diethers as selective PDEIV inhibitors |
| NZ276172A (en) | 1994-02-10 | 1998-02-26 | Pfizer | 5-heteroarylindole derivatives as benzodiazepine receptor site agonists and antagonists, 5-(hetero)arylaminoindole intermediates |
| US5563143A (en) | 1994-09-21 | 1996-10-08 | Pfizer Inc. | Catechol diether compounds as inhibitors of TNF release |
| US5972980A (en) | 1995-10-05 | 1999-10-26 | Warner-Lambert Company | Method for treating and preventing inflammation and atherosclerosis |
| US6001866A (en) | 1995-10-05 | 1999-12-14 | Warner-Lambert Company | Method for treating and preventing inflammation and atherosclerosis |
| US6548524B2 (en) * | 1996-10-16 | 2003-04-15 | American Cyanamid Company | Preparation and use of ortho-sulfonamido bicyclic heteroaryl hydroxamic acids as matrix metalloproteinase and TACE inhibitors |
| EP0846689B1 (de) | 1996-12-09 | 2004-01-14 | Pfizer Inc. | Benzimidazol-Verbindungen |
| US6414008B1 (en) | 1997-04-29 | 2002-07-02 | Boehringer Ingelheim Pharma Kg | Disubstituted bicyclic heterocycles, the preparation thereof, and their use as pharmaceutical compositions |
| WO1999000372A1 (fr) | 1997-06-27 | 1999-01-07 | Fujisawa Pharmaceutical Co., Ltd. | Sulfamides et leur utilisation medicale |
| US5990146A (en) * | 1997-08-20 | 1999-11-23 | Warner-Lambert Company | Benzimidazoles for inhibiting protein tyrosine kinase mediated cellular proliferation |
| US6465484B1 (en) | 1997-09-26 | 2002-10-15 | Merck & Co., Inc. | Angiogenesis inhibitors |
| US6162804A (en) | 1997-09-26 | 2000-12-19 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
| US6534503B1 (en) | 1998-04-28 | 2003-03-18 | Lion Bioscience Ag | Melanocortin receptor-3 ligands to treat sexual dysfunction |
| EP1101758A4 (de) | 1998-07-28 | 2002-04-03 | Nihon Nohyaku Co Ltd | Kondensierte heterocyclische dicarbonsäurediamid-derivate oder salze davon, herbizide und ihre verwendung |
| US6326379B1 (en) | 1998-09-16 | 2001-12-04 | Bristol-Myers Squibb Co. | Fused pyridine inhibitors of cGMP phosphodiesterase |
| US6348032B1 (en) * | 1998-11-23 | 2002-02-19 | Cell Pathways, Inc. | Method of inhibiting neoplastic cells with benzimidazole derivatives |
| US6329383B1 (en) | 1999-01-25 | 2001-12-11 | Pharmacia Ab | 2-amino-5-pyrimidine acetic acid compounds |
| US6281237B1 (en) | 1999-04-02 | 2001-08-28 | Neurogen Corporation | N-phenyl benzimidazolecarboxamide and N-phenyl indolecarboxamide derivatives |
| US6816481B1 (en) * | 1999-04-09 | 2004-11-09 | Sbc Technology Resources, Inc. | Internet caller identification system and method |
| CO5190696A1 (es) | 1999-06-16 | 2002-08-29 | Smithkline Beecham Corp | Antagonistas de los receptores il-8 |
| WO2001012600A1 (en) | 1999-08-12 | 2001-02-22 | Cor Therapeutics, Inc. | INHIBITORS OF FACTOR Xa |
| DE19939463A1 (de) | 1999-08-20 | 2001-02-22 | Boehringer Ingelheim Pharma | Aminocarbonyl-substituierte Benzimidazolderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
| US6512000B1 (en) | 1999-08-20 | 2003-01-28 | Boehringer Ingelheim Pharma Kg | Aminocarbonyl-substituted benzimidazoles having tryptase-inhibitory activity |
| DE60016858T2 (de) | 1999-09-13 | 2005-12-08 | Eastman Kodak Co. | Photographisches Material mit verbesserter Farbwiedergabe |
| EP1214330A1 (de) * | 1999-09-21 | 2002-06-19 | LION Bioscience AG | Benzimidazol-derivate sowie diese enthaltende kombinatorische bibliotheken |
| US6316474B1 (en) | 1999-10-29 | 2001-11-13 | Merck & Co., Inc. | 2-benzyl and 2-heteroaryl benzimidazole NMDA/NR2B antagonists |
| AU2001234705A1 (en) | 2000-02-01 | 2001-08-14 | Cor Therapeutics, Inc. | Indalone and benzimidazolone inhibitors of factor xa |
| US20030190714A1 (en) * | 2000-03-10 | 2003-10-09 | Roberds Steven L. | Human ion channels |
| US6448281B1 (en) | 2000-07-06 | 2002-09-10 | Boehringer Ingelheim (Canada) Ltd. | Viral polymerase inhibitors |
| WO2002030886A2 (en) | 2000-10-12 | 2002-04-18 | Matthews Barry R | Heterocyclic angiogenesis inhibitors |
| AU3950802A (en) | 2000-12-07 | 2002-06-18 | Cv Therapeutics Inc | Abca-1 elevating compounds |
| NZ526622A (en) | 2000-12-11 | 2006-07-28 | Amgen Sf Llc | CXCR3 antagonists |
| GB0102109D0 (en) | 2001-01-26 | 2001-03-14 | Syngenta Ltd | Chemical process |
| CN1235583C (zh) | 2001-03-05 | 2006-01-11 | 特兰斯泰克制药公司 | 用作治疗剂的苯并咪唑衍生物 |
| US20030109714A1 (en) | 2001-03-22 | 2003-06-12 | Neil Wishart | Transition metal mediated process |
| US20030009034A1 (en) | 2001-03-22 | 2003-01-09 | Neil Wishart | Transition metal mediated process |
| US6794379B2 (en) | 2001-06-06 | 2004-09-21 | Tularik Inc. | CXCR3 antagonists |
| TWI281861B (en) * | 2002-01-29 | 2007-06-01 | Sanofi Aventis | A pharmaceutical composition comprising SANORG 34006 for treatment and secondary prophylaxis of venous thromboembolic events in patients with deep venous thrombosis |
| ATE457025T1 (de) * | 2002-05-23 | 2010-02-15 | Cytopia Res Pty Ltd | Kinaseinhibitoren |
| AU2002951247A0 (en) | 2002-09-06 | 2002-09-19 | Alchemia Limited | Compounds that interact with kinases |
| US7227035B2 (en) | 2002-11-18 | 2007-06-05 | Chemocentryx | Bis-aryl sulfonamides |
| BRPI0413746A (pt) | 2003-08-21 | 2006-10-24 | Osi Pharm Inc | composto ou um seu n-óxido ou seu sal farmaceuticamente aceitável, composição, e, método de tratamento de distúrbio hiperproliferativo |
-
2005
- 2005-11-30 CA CA002589770A patent/CA2589770A1/en not_active Abandoned
- 2005-11-30 CN CNA2005800476125A patent/CN101193867A/zh active Pending
- 2005-11-30 AR ARP050105014A patent/AR052419A1/es not_active Application Discontinuation
- 2005-11-30 KR KR1020077015090A patent/KR20070086865A/ko not_active Withdrawn
- 2005-11-30 JP JP2007544433A patent/JP2008521903A/ja active Pending
- 2005-11-30 EP EP05852400A patent/EP1831206B1/de not_active Expired - Lifetime
- 2005-11-30 BR BRPI0518794-0A patent/BRPI0518794A2/pt not_active IP Right Cessation
- 2005-11-30 US US11/290,028 patent/US7419995B2/en not_active Expired - Fee Related
- 2005-11-30 AU AU2005312028A patent/AU2005312028A1/en not_active Abandoned
- 2005-11-30 AT AT05852400T patent/ATE521604T1/de not_active IP Right Cessation
- 2005-11-30 WO PCT/US2005/043114 patent/WO2006060381A2/en not_active Ceased
- 2005-12-01 TW TW094142316A patent/TW200633704A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1831206B1 (de) | 2011-08-24 |
| WO2006060381A3 (en) | 2006-12-28 |
| AU2005312028A1 (en) | 2006-06-08 |
| BRPI0518794A2 (pt) | 2008-12-09 |
| TW200633704A (en) | 2006-10-01 |
| KR20070086865A (ko) | 2007-08-27 |
| US7419995B2 (en) | 2008-09-02 |
| AR052419A1 (es) | 2007-03-21 |
| US20060116402A1 (en) | 2006-06-01 |
| JP2008521903A (ja) | 2008-06-26 |
| CA2589770A1 (en) | 2006-06-08 |
| EP1831206A2 (de) | 2007-09-12 |
| CN101193867A (zh) | 2008-06-04 |
| WO2006060381A2 (en) | 2006-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE423121T1 (de) | Diphenylimidazopyrimidin- und -imidazolamine als b-sekretase-inhibitoren | |
| DK1592686T3 (da) | Gyrase-inhibitorer og anvendelser deraf | |
| ATE413395T1 (de) | N-substituierte pyrazolyl-amidyl-benzimidazolyl-c-kit-inhibitor n | |
| DK1940839T3 (da) | Pyridopyrimidione Inhibitors of P13Ka | |
| CY2014011I1 (el) | Χορηγηση αναστολεων διπεπτιδυλοπεπτιδασης | |
| PT1586571E (pt) | Inibidores da dipeptidil-peptidase | |
| NO20081604L (no) | Nitrogeninneholdende heterocyklisk forbindelse og farmasøytisk anvendelse derav | |
| DK1713806T3 (da) | Forbindelser og sammensætninger som proteinkinaseinhibitorer | |
| NO20054453L (no) | P38 inhibitorer og fremgangsmater for anvendelse derav | |
| DK1606283T3 (da) | P38-inhibitorer og fremgangsmåder til anvendelse deraf | |
| CY2013042I1 (el) | Αναστολεις πυριδυλιου της σηματοδοτησης hedgehog | |
| DE602004018837D1 (de) | Ptidase-iv-inhibitoren | |
| DE602006000925D1 (de) | Tragbares Spielegerät und Hülle | |
| DE602005019971D1 (de) | Inhibitoren von cysteinprotease | |
| EP1789381A4 (de) | Histondeacetylase-hemmer | |
| IS8597A (is) | Samsetningar rísedrónats og aðferðir við notkun þess | |
| DK1771446T3 (da) | Azaindolinhibitorer af MTP og APOB | |
| DE602005003819D1 (de) | Perfluoroelastomer- und fluoroplastikgemische | |
| ITMI20041869A1 (it) | Nuovi inibitori delle istone deacetilasi | |
| ATE462692T1 (de) | 3-amino-1-arylpropyl-indole als monoamin- wiederaufnahmehemmer | |
| EP1613311A4 (de) | Hif-1-hemmer | |
| ATE545642T1 (de) | Mmp-inhibitoren | |
| DE602005012640D1 (de) | Setzgerät und Magazinvorrichtung | |
| DK1840121T3 (da) | Glycinderivat og anvendelse heraf | |
| EP1841419A4 (de) | Cathepsin-k- und adipositas-inhibitoren |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |