ATE523509T1 - 13,13a-dihydroberberinderivate, ihre pharmazeutischen zusammensetzungen und verwendung - Google Patents

13,13a-dihydroberberinderivate, ihre pharmazeutischen zusammensetzungen und verwendung

Info

Publication number
ATE523509T1
ATE523509T1 AT07816496T AT07816496T ATE523509T1 AT E523509 T1 ATE523509 T1 AT E523509T1 AT 07816496 T AT07816496 T AT 07816496T AT 07816496 T AT07816496 T AT 07816496T AT E523509 T1 ATE523509 T1 AT E523509T1
Authority
AT
Austria
Prior art keywords
dihydroberberine
derivatives
pharmaceutical compositions
fatty liver
present compounds
Prior art date
Application number
AT07816496T
Other languages
English (en)
Inventor
Lihong Hu
Jiming Ye
Jingya Li
David James
Edward Kraegen
Hankun Zhang
Zhe Cheng
Jia Li
Original Assignee
Shanghai Inst Materia Medica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Inst Materia Medica filed Critical Shanghai Inst Materia Medica
Application granted granted Critical
Publication of ATE523509T1 publication Critical patent/ATE523509T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
AT07816496T 2006-09-30 2007-09-30 13,13a-dihydroberberinderivate, ihre pharmazeutischen zusammensetzungen und verwendung ATE523509T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN2006101404296A CN101153039B (zh) 2006-09-30 2006-09-30 13，13a-二氢小檗碱衍生物及其药物组合物和用途
PCT/CN2007/002882 WO2008040192A1 (en) 2006-09-30 2007-09-30 13,13a-DIHYDROBERBERINE DERIVATIVES, THEIR PHARMACEUTICAL COMPOSITION AND USE

Publications (1)

Publication Number Publication Date
ATE523509T1 true ATE523509T1 (de) 2011-09-15

Family

ID=39254944

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07816496T ATE523509T1 (de) 2006-09-30 2007-09-30 13,13a-dihydroberberinderivate, ihre pharmazeutischen zusammensetzungen und verwendung

Country Status (6)

Country Link
US (1) US20100113494A1 (de)
EP (1) EP2070926B1 (de)
JP (1) JP2010504919A (de)
CN (1) CN101153039B (de)
AT (1) ATE523509T1 (de)
WO (1) WO2008040192A1 (de)

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Also Published As

Publication number Publication date
EP2070926B1 (de) 2011-09-07
CN101153039B (zh) 2010-12-01
US20100113494A1 (en) 2010-05-06
WO2008040192A1 (en) 2008-04-10
EP2070926A1 (de) 2009-06-17
JP2010504919A (ja) 2010-02-18
EP2070926A4 (de) 2010-04-14
CN101153039A (zh) 2008-04-02

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