ATE524068T1 - Verfahren zur herstellung eines 2-phenyl-1h- phenantrhoä9,10-düimidazol-derivates - Google Patents
Verfahren zur herstellung eines 2-phenyl-1h- phenantrhoä9,10-düimidazol-derivatesInfo
- Publication number
- ATE524068T1 ATE524068T1 AT06827868T AT06827868T ATE524068T1 AT E524068 T1 ATE524068 T1 AT E524068T1 AT 06827868 T AT06827868 T AT 06827868T AT 06827868 T AT06827868 T AT 06827868T AT E524068 T1 ATE524068 T1 AT E524068T1
- Authority
- AT
- Austria
- Prior art keywords
- phenyl
- phenantrho
- disubstituted
- useful
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 4
- 208000002193 Pain Diseases 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 102100033076 Prostaglandin E synthase Human genes 0.000 abstract 2
- 101710096361 Prostaglandin E synthase Proteins 0.000 abstract 2
- 150000002460 imidazoles Chemical class 0.000 abstract 2
- 208000000094 Chronic Pain Diseases 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 208000005298 acute pain Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000011031 large-scale manufacturing process Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73930905P | 2005-11-23 | 2005-11-23 | |
| PCT/US2006/044696 WO2007061853A2 (en) | 2005-11-23 | 2006-11-17 | Process for synthesizing 2-phenyl-1h-phenantrho[9,10-d]imidazole derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE524068T1 true ATE524068T1 (de) | 2011-09-15 |
Family
ID=38067782
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06827868T ATE524068T1 (de) | 2005-11-23 | 2006-11-17 | Verfahren zur herstellung eines 2-phenyl-1h- phenantrhoä9,10-düimidazol-derivates |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20090203922A1 (de) |
| EP (1) | EP1954134B1 (de) |
| AT (1) | ATE524068T1 (de) |
| WO (1) | WO2007061853A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2643562A1 (en) * | 2006-02-24 | 2007-08-30 | Anh Chau | 2-(phenyl or heterocyclic)-1h-phenanthro[9,10-d]imidazoles |
| ES2444695T3 (es) | 2006-06-23 | 2014-02-26 | Alethia Biotherapeutics Inc. | Polinucleótidos y polipéptidos implicados en el cáncer |
| JP5433992B2 (ja) * | 2008-06-26 | 2014-03-05 | Ｄｉｃ株式会社 | フルオロクロマノール誘導体の製造方法 |
| JP5433996B2 (ja) * | 2008-07-10 | 2014-03-05 | Ｄｉｃ株式会社 | フルオロフェノール誘導体の製造方法 |
| CA2740900C (en) | 2008-11-03 | 2019-09-24 | Alethia Biotherapeutics Inc. | Antibodies that specifically block the biological activity of a tumor antigen |
| GB201006846D0 (en) | 2010-04-23 | 2010-06-09 | Glaxo Group Ltd | Novel compounds |
| SI3173427T1 (sl) | 2011-03-31 | 2019-08-30 | ADC Therapeutics SA, | Protitelesa proti antigenu 1, povezanemu z ledvicami, in antigen vezavni fragmenti le-tega |
| KR102102239B1 (ko) | 2012-01-09 | 2020-04-21 | 에이디씨 테라퓨틱스 에스에이 | 유방암을 치료하기 위한 방법 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060106020A1 (en) * | 2004-04-28 | 2006-05-18 | Rodgers James D | Tetracyclic inhibitors of Janus kinases |
| US7442716B2 (en) * | 2004-12-17 | 2008-10-28 | Merck Frosst Canada Ltd. | 2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors |
| JP5086809B2 (ja) * | 2004-12-17 | 2012-11-28 | メルク カナダ インコーポレイテッド | ｍＰＧＥＳ−１阻害剤としての２−（フェニルまたはヘテロ環式）−１Ｈ−フェナントロ［９，１０−ｄ］イミダゾール |
-
2006
- 2006-11-17 EP EP06827868A patent/EP1954134B1/de not_active Not-in-force
- 2006-11-17 WO PCT/US2006/044696 patent/WO2007061853A2/en not_active Ceased
- 2006-11-17 US US12/085,258 patent/US20090203922A1/en not_active Abandoned
- 2006-11-17 AT AT06827868T patent/ATE524068T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007061853A3 (en) | 2007-11-22 |
| WO2007061853A2 (en) | 2007-05-31 |
| EP1954134A2 (de) | 2008-08-13 |
| EP1954134A4 (de) | 2010-08-04 |
| EP1954134B1 (de) | 2011-09-14 |
| US20090203922A1 (en) | 2009-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |