ATE524202T1 - Abstandhalter mit beschichtung zur verwendung mit einer implantatvorrichtung - Google Patents

Abstandhalter mit beschichtung zur verwendung mit einer implantatvorrichtung

Info

Publication number
ATE524202T1
ATE524202T1 AT08252074T AT08252074T ATE524202T1 AT E524202 T1 ATE524202 T1 AT E524202T1 AT 08252074 T AT08252074 T AT 08252074T AT 08252074 T AT08252074 T AT 08252074T AT E524202 T1 ATE524202 T1 AT E524202T1
Authority
AT
Austria
Prior art keywords
bone
spacer
healing
coating
implant device
Prior art date
Application number
AT08252074T
Other languages
English (en)
Inventor
Ralf Klabunde
Hallie E Brinkerhuff
Michael E Hawkins
Daniel Buehler
Kai Zhang
Original Assignee
Zimmer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zimmer Inc filed Critical Zimmer Inc
Application granted granted Critical
Publication of ATE524202T1 publication Critical patent/ATE524202T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8028—Cushions, i.e. elements forming interface between bone plate and bone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
    • A61B17/8033—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers
    • A61B17/8047—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers wherein the additional element surrounds the screw head in the plate hole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00004—(bio)absorbable, (bio)resorbable or resorptive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00867—Material properties shape memory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252—Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Medical Informatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)
AT08252074T 2007-06-19 2008-06-17 Abstandhalter mit beschichtung zur verwendung mit einer implantatvorrichtung ATE524202T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/765,007 US8309521B2 (en) 2007-06-19 2007-06-19 Spacer with a coating thereon for use with an implant device

Publications (1)

Publication Number Publication Date
ATE524202T1 true ATE524202T1 (de) 2011-09-15

Family

ID=39765211

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08252074T ATE524202T1 (de) 2007-06-19 2008-06-17 Abstandhalter mit beschichtung zur verwendung mit einer implantatvorrichtung

Country Status (5)

Country Link
US (1) US8309521B2 (de)
EP (1) EP2005978B1 (de)
JP (1) JP2009011825A (de)
AT (1) ATE524202T1 (de)
CA (1) CA2635320A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8740955B2 (en) 2005-02-15 2014-06-03 Zimmer, Inc. Bone screw with multiple thread profiles for far cortical locking and flexible engagement to a bone
US20070191848A1 (en) * 2006-02-01 2007-08-16 Zimmer Technology, Inc. Hydrogel bone plate spacer
US9642658B2 (en) * 2008-10-15 2017-05-09 Orthoclip Llc Device and method for delivery of therapeutic agents via internal implants
US20100130959A1 (en) * 2008-10-15 2010-05-27 Palmetto Biomedical, Inc. Device and method for delivery of therapeutic agents via artificial internal implants
US8506608B2 (en) 2009-03-24 2013-08-13 Douglas Cerynik Orthopedic fixation device with bioresorbable layer
CN102481187B (zh) * 2009-03-31 2016-06-08 医学嵌入公司暨Imds共同创新公司 双束前十字韧带修复
CN102470197B (zh) * 2009-07-16 2015-09-23 A·D·多斯塔 骨植入物
US8790379B2 (en) 2010-06-23 2014-07-29 Zimmer, Inc. Flexible plate fixation of bone fractures
US8882815B2 (en) 2010-06-23 2014-11-11 Zimmer, Inc. Flexible plate fixation of bone fractures
US8968402B2 (en) 2011-10-18 2015-03-03 Arthrocare Corporation ACL implants, instruments, and methods
KR102184970B1 (ko) * 2011-10-28 2020-12-03 백스터 인터내셔널 인코포레이티드 뼈 지혈용 비-수성 조성물, 그의 사용 방법 및 제조 방법
KR101213355B1 (ko) * 2011-12-27 2012-12-18 오스템임플란트 주식회사 초기 안정성이 증진된 치과용 임플란트 및 그 제조 방법
US9295508B2 (en) * 2012-02-03 2016-03-29 Zimmer, Inc. Bone plate for elastic osteosynthesis
DE102012006454A1 (de) 2012-03-30 2013-10-02 Heraeus Medical Gmbh Antiinfektiver Abstandshalter für Osteosyntheseplatten
CH710695B1 (it) 2015-02-03 2022-11-30 Brianza Stefano Dispositivo per fissazione variabile di frammenti ossei.
GB201619923D0 (en) * 2016-11-24 2017-01-11 Vetsos Ltd Orthopaedic Apparatus
NL2020071B1 (en) 2017-12-12 2019-06-21 Umc Utrecht Holding Bv Deformable body and combination of such deformable body and a surgical screw element.
US11039865B2 (en) 2018-03-02 2021-06-22 Stryker European Operations Limited Bone plates and associated screws
US11701150B2 (en) * 2018-08-24 2023-07-18 Laboratoires Bodycad Inc. Patient-specific fixation plate with spacing elements
US11324538B2 (en) 2019-12-04 2022-05-10 Biomet Manufacturing, Llc Active bone plate
WO2022182987A1 (en) * 2021-02-25 2022-09-01 Biomedtrix, Llc Orthopedic implant for bone realignment

Family Cites Families (282)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH497891A (de) * 1968-09-03 1970-10-31 Straumann Inst Ag Für die operative Knochenbehandlung dienendes Implantat aus Titan oder einer Legierung auf Titanbasis
US3605123A (en) * 1969-04-29 1971-09-20 Melpar Inc Bone implant
US4004064A (en) * 1974-01-02 1977-01-18 Joseph W. Aidlin Protective coating for articles
US4338926A (en) * 1980-11-21 1982-07-13 Howmedica, Inc. Bone fracture prosthesis with controlled stiffness
US4570271A (en) * 1981-07-27 1986-02-18 Battelle Development Corporation Porous coatings from wire mesh for bone implants
US4563489A (en) 1984-02-10 1986-01-07 University Of California Biodegradable organic polymer delivery system for bone morphogenetic protein
DE3414924A1 (de) 1984-04-19 1985-10-31 Klaus Dr.med. Dr.med.habil. 8000 München Draenert Beschichtetes verankerungsteil fuer implantate
DE3445738A1 (de) 1984-12-14 1986-06-19 Draenert Klaus Implantat zur knochenverstaerkung und verankerung von knochenschrauben, implantaten oder implantatteilen
CH657519A5 (en) 1985-05-17 1986-09-15 Ines Blaettler Surgical implants and repair plates
US5470829A (en) 1988-11-17 1995-11-28 Prisell; Per Pharmaceutical preparation
US5306500A (en) 1988-11-21 1994-04-26 Collagen Corporation Method of augmenting tissue with collagen-polymer conjugates
DE3841286A1 (de) 1988-12-08 1990-06-13 Appel Hans Guenter Osteosyntheseimplantate
US4923471A (en) * 1989-10-17 1990-05-08 Timesh, Inc. Bone fracture reduction and fixation devices with identity tags
CA1317173C (en) * 1989-11-08 1993-05-04 Amnon Foux Plate for broken bone fixation
US5492697A (en) 1990-03-05 1996-02-20 Board Of Regents, Univ. Of Texas System Biodegradable implant for fracture nonunions
AU7998091A (en) 1990-05-17 1991-12-10 Harbor Medical Devices, Inc. Medical device polymer
DE69016433T2 (de) * 1990-05-19 1995-07-20 Papyrin Anatolij Nikiforovic Beschichtungsverfahren und -vorrichtung.
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5198308A (en) * 1990-12-21 1993-03-30 Zimmer, Inc. Titanium porous surface bonded to a cobalt-based alloy substrate in an orthopaedic implant device
DE4106971C1 (de) 1991-03-05 1992-03-19 Eska Medical Luebeck Medizintechnik Gmbh & Co, 2400 Luebeck, De
SE9101853D0 (sv) 1991-06-17 1991-06-17 Jonas Wadstroem Improved tissue ashesive
EP0523926A3 (en) 1991-07-15 1993-12-01 Smith & Nephew Richards Inc Prosthetic implants with bioabsorbable coating
US5573934A (en) 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
US5383934A (en) * 1992-03-04 1995-01-24 Implant Sciences, Corporation Method for ion beam treating orthopaedic implant components
US5282861A (en) * 1992-03-11 1994-02-01 Ultramet Open cell tantalum structures for cancellous bone implants and cell and tissue receptors
US5334640A (en) 1992-04-08 1994-08-02 Clover Consolidated, Ltd. Ionically covalently crosslinked and crosslinkable biocompatible encapsulation compositions and methods
DE4213634A1 (de) 1992-04-24 1993-10-28 Cassella Ag 2,4-Dioxo-imidazolidin-Derivate
DE4228717A1 (de) 1992-08-28 1994-03-03 Cassella Ag Imidazolidin-Derivate
DE4308034A1 (de) 1993-03-13 1994-09-15 Cassella Ag Neue Heterocyclen, ihre Herstellung und ihre Verwendung
NO940913L (no) 1993-03-26 1994-09-27 Bristol Myers Squibb Co Preparater for kontrollert frigivelse av biologisk aktiv TGF-
US5824651A (en) 1993-05-10 1998-10-20 Universite De Montreal Process for modification of implant surface with bioactive conjugates for improved integration
CA2175049A1 (en) 1993-10-28 1995-05-04 Timothy Ringeisen Improved process and device for treating and healing a bone void
US5565407A (en) 1993-12-27 1996-10-15 University Of Kansas Center For Research, Inc. Biologically active agent encapsulated in biodegradable starch/polymer matrices
CA2142636C (en) * 1994-02-18 2005-09-20 Salvatore Caldarise Implantable articles with as-cast macrotextured surface regions and method of manufacturing the same
US5665118A (en) * 1994-02-18 1997-09-09 Johnson & Johnson Professional, Inc. Bone prostheses with direct cast macrotextured surface regions and method for manufacturing the same
US5947893A (en) 1994-04-27 1999-09-07 Board Of Regents, The University Of Texas System Method of making a porous prothesis with biodegradable coatings
US5534524A (en) 1994-05-09 1996-07-09 Board Of Regents, The University Of Texas System Suppression of bone resorption by quinolines
US5788979A (en) 1994-07-22 1998-08-04 Inflow Dynamics Inc. Biodegradable coating with inhibitory properties for application to biocompatible materials
US6339130B1 (en) 1994-07-22 2002-01-15 United States Surgical Corporation Bioabsorbable branched polymers containing units derived from dioxanone and medical/surgical devices manufactured therefrom
US6179817B1 (en) 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
US6120536A (en) 1995-04-19 2000-09-19 Schneider (Usa) Inc. Medical devices with long term non-thrombogenic coatings
US6099562A (en) 1996-06-13 2000-08-08 Schneider (Usa) Inc. Drug coating with topcoat
US5693515A (en) 1995-04-28 1997-12-02 Arris Pharmaceutical Corporation Metal complexed serine protease inhibitors
US5688855A (en) 1995-05-01 1997-11-18 S.K.Y. Polymers, Inc. Thin film hydrophilic coatings
EP0842209B1 (de) 1995-07-28 2006-10-11 Genzyme Corporation Biologische abbaubare multiblokhydrogene und ihre verwendung wie trägerstoffe fur kontrollierte freisetzung pharmakologisch activen werstoffe und gewebekontaktmaterialen
US5535810A (en) * 1995-07-28 1996-07-16 Zimmer, Inc. Cast orthopaedic implant and method of making same
CN1052915C (zh) 1995-11-27 2000-05-31 中国医学科学院生物医学工程研究所 用于携载基因的蛋白质涂层医用载体及其制作方法
US7883693B2 (en) 1995-12-18 2011-02-08 Angiodevice International Gmbh Compositions and systems for forming crosslinked biomaterials and methods of preparation of use
PT876165E (pt) 1995-12-18 2006-10-31 Angiotech Biomaterials Corp Composicoes de polimeros reticulados e processos para a sua utilizacao
ATE273723T1 (de) 1996-02-29 2004-09-15 Bioactive Bone Substitute Oy A Osteogene vorrichtungen und methode zur herstellung derselben
US5932299A (en) 1996-04-23 1999-08-03 Katoot; Mohammad W. Method for modifying the surface of an object
US5928916A (en) 1996-04-25 1999-07-27 Medtronic, Inc. Ionic attachment of biomolecules with a guanidino moiety to medical device surfaces
US5925552A (en) 1996-04-25 1999-07-20 Medtronic, Inc. Method for attachment of biomolecules to medical devices surfaces
US20040106985A1 (en) 1996-04-26 2004-06-03 Jang G. David Intravascular stent
US5893846A (en) * 1996-05-15 1999-04-13 Symbiosis Corp. Ceramic coated endoscopic scissor blades and a method of making the same
US5811151A (en) 1996-05-31 1998-09-22 Medtronic, Inc. Method of modifying the surface of a medical device
US6143037A (en) 1996-06-12 2000-11-07 The Regents Of The University Of Michigan Compositions and methods for coating medical devices
ZA978537B (en) 1996-09-23 1998-05-12 Focal Inc Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
AU7178698A (en) 1996-11-15 1998-06-03 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
DE69732721T2 (de) 1996-12-03 2006-05-18 Osteobiologics, Inc., San Antonio Biologisch abbaubare kunstoff-folien
US5980551A (en) 1997-02-07 1999-11-09 Endovasc Ltd., Inc. Composition and method for making a biodegradable drug delivery stent
KR20010006026A (ko) 1997-04-03 2001-01-15 존스 홉킨스 유니버시티 스쿨 오브 메디슨 생물분해성 테레프탈레이트 폴리에스테르-폴리(포스페이트) 중합체, 조성물, 약품 및 그의 제조방법과 이용방법
UA54505C2 (uk) 1997-04-03 2003-03-17 Гілфорд Фармасьютікалз Інк. Полімери, що біологічно розкладаються, зшиті фосфатами, композиції, вироби і способи для їх виготовлення і використання
ATE229038T1 (de) 1997-04-04 2002-12-15 Fidia Advanced Biopolymers Srl N-sulfatierte hyaluronsäureverbindungen, ihre derivate und verfahren zu ihrer herstellung
US5912225A (en) 1997-04-14 1999-06-15 Johns Hopkins Univ. School Of Medicine Biodegradable poly (phosphoester-co-desaminotyrosyl L-tyrosine ester) compounds, compositions, articles and methods for making and using the same
AU7121198A (en) 1997-04-18 1998-11-13 California Institute Of Technology Multifunctional polymeric tissue coatings
US6486232B1 (en) 1997-04-18 2002-11-26 Cambridge Scientific, Inc. Bioerodible polymeric semi-interpenetrating network alloys for internal fixation devices and bone cements
WO1998057671A2 (en) 1997-06-18 1998-12-23 Boston Scientific Corporation Polycarbonate-polyurethane dispersions for thrombo-resistant coatings
US6121027A (en) 1997-08-15 2000-09-19 Surmodics, Inc. Polybifunctional reagent having a polymeric backbone and photoreactive moieties and bioactive groups
US6316522B1 (en) 1997-08-18 2001-11-13 Scimed Life Systems, Inc. Bioresorbable hydrogel compositions for implantable prostheses
EP0933367A1 (de) 1997-12-19 1999-08-04 Hoechst Marion Roussel Deutschland GmbH Acylguanidin Derivate als Inhibitoren von Knochenaufsauge und als Vitronectin Rezeptor Antagonisten
GB9801061D0 (en) 1998-01-20 1998-03-18 Univ Nottingham Patterning technique
US6313119B1 (en) 1998-01-23 2001-11-06 Adventis Pharma Deutschland Gmbh Sulfonamide derivatives as inhibitors of bone resorption and as inhibitors of cell adhesion
US6221425B1 (en) 1998-01-30 2001-04-24 Advanced Cardiovascular Systems, Inc. Lubricious hydrophilic coating for an intracorporeal medical device
US5938664A (en) * 1998-03-31 1999-08-17 Zimmer, Inc. Orthopaedic bone plate
US6364856B1 (en) 1998-04-14 2002-04-02 Boston Scientific Corporation Medical device with sponge coating for controlled drug release
US6254634B1 (en) 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
US6500481B1 (en) 1998-06-11 2002-12-31 Johnson & Johnson Vision Care, Inc. Biomedical devices with amid-containing coatings
US20020087184A1 (en) 1998-06-18 2002-07-04 Eder Joseph C. Water-soluble coating for bioactive devices
US6153252A (en) 1998-06-30 2000-11-28 Ethicon, Inc. Process for coating stents
US6551355B1 (en) 1998-08-14 2003-04-22 Cambridge Scientific, Inc. Tissue transplant coated with biocompatible biodegradable polymer
ES2187195T3 (es) 1998-09-11 2003-05-16 Gerhard Dr Schmidmaier Implantes biologicamente activos.
US6921811B2 (en) 1998-09-22 2005-07-26 Biosurface Engineering Technologies, Inc. Bioactive coating composition and methods
US20030007991A1 (en) 1998-09-25 2003-01-09 Masters David B. Devices including protein matrix materials and methods of making and using thereof
US20040009535A1 (en) 1998-11-27 2004-01-15 Celltech R&D, Inc. Compositions and methods for increasing bone mineralization
JP2002532160A (ja) 1998-12-17 2002-10-02 ケンブリッジ サイエンティフィック， インコーポレイテッド 皮質骨同種移植片の順序付けられた組み込み
US6395029B1 (en) 1999-01-19 2002-05-28 The Children's Hospital Of Philadelphia Sustained delivery of polyionic bioactive agents
US6514515B1 (en) 1999-03-04 2003-02-04 Tepha, Inc. Bioabsorbable, biocompatible polymers for tissue engineering
US6368658B1 (en) 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
NZ515911A (en) 1999-06-04 2004-02-27 Alza Corp Implantable gel compositions and method of manufacture
WO2000077281A1 (en) 1999-06-10 2000-12-21 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Encapsulation of crystals via multilayer coatings
FR2794649B1 (fr) 1999-06-11 2003-04-11 Solutions Biomateriau a base d'un derive de dextrane insolubilise et d'un facteur de croissance, son procede de preparation et ses applications
US6258121B1 (en) 1999-07-02 2001-07-10 Scimed Life Systems, Inc. Stent coating
US6309660B1 (en) 1999-07-28 2001-10-30 Edwards Lifesciences Corp. Universal biocompatible coating platform for medical devices
FI19991852A7 (fi) 1999-09-01 2001-03-02 Yli Urpo Antti Uusi monikerroksinen materiaali, joka käsittää vaikuttavan ainesosan, ja sen valmistus
US6540746B1 (en) * 1999-09-30 2003-04-01 Sulzer Orthopedics Ltd. Bone plate for splinting a fracture at a bone with a plurality of bone screws
US6461631B1 (en) 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
JP2003521973A (ja) * 1999-11-30 2003-07-22 ビオンクス インプランツ オサケユイチア 生体吸収性骨促進性固定プレート
US20060013850A1 (en) 1999-12-03 2006-01-19 Domb Abraham J Electropolymerizable monomers and polymeric coatings on implantable devices prepared therefrom
AU2623201A (en) 1999-12-30 2001-07-16 Kam W Leong Controlled delivery of therapeutic agents by insertable medical devices
ATE431165T1 (de) 2000-01-25 2009-05-15 Edwards Lifesciences Corp Bioaktive beschichtungen zur vermeidung von gewebewachstum auf künstlichen herzklappen
JP2003521351A (ja) 2000-02-04 2003-07-15 イソティス エヌ．ブイ． 蛋白質性コーティング
US20070055367A1 (en) 2000-03-15 2007-03-08 Orbus Medical Technologies, Inc. Medical device with coating that promotes endothelial cell adherence and differentiation
US9522217B2 (en) 2000-03-15 2016-12-20 Orbusneich Medical, Inc. Medical device with coating for capturing genetically-altered cells and methods for using same
US20050271701A1 (en) 2000-03-15 2005-12-08 Orbus Medical Technologies, Inc. Progenitor endothelial cell capturing with a drug eluting implantable medical device
US20030229393A1 (en) 2001-03-15 2003-12-11 Kutryk Michael J. B. Medical device with coating that promotes cell adherence and differentiation
US6869445B1 (en) 2000-05-04 2005-03-22 Phillips Plastics Corp. Packable ceramic beads for bone repair
US6673385B1 (en) 2000-05-31 2004-01-06 Advanced Cardiovascular Systems, Inc. Methods for polymeric coatings stents
DE10029520A1 (de) 2000-06-21 2002-01-17 Merck Patent Gmbh Beschichtung für metallische Implantatmaterialien
CN1471412B8 (zh) 2000-06-29 2016-06-15 生物合成技术加拿大公司 用于修复和再生软骨和其它组织的组合物以及该组合物的用途
US6939568B2 (en) 2001-04-23 2005-09-06 Nucryst Pharmaceuticals Corp. Treatment of inflammatory skin conditions
US6451373B1 (en) 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis
ES2169681B1 (es) 2000-08-10 2003-10-01 Osfarma S L Metodo de produccion de filmes de quitosan con una alta capacidad de adherencia celular, producto obrenido y aplicaciones.
JP2004520088A (ja) 2000-08-15 2004-07-08 サーモディックス，インコーポレイティド 薬剤混和マトリックス
EP1309279A4 (de) 2000-08-17 2008-04-09 Tyco Healthcare Nähte und beschichtungen aus therapeutischen absorbierbarem glas
US20060286064A1 (en) 2000-08-30 2006-12-21 Medivas, Llc Therapeutic polymers and methods
US7766956B2 (en) 2000-09-22 2010-08-03 Boston Scientific Scimed, Inc. Intravascular stent and assembly
US7261735B2 (en) 2001-05-07 2007-08-28 Cordis Corporation Local drug delivery devices and methods for maintaining the drug coatings thereon
US20060222756A1 (en) 2000-09-29 2006-10-05 Cordis Corporation Medical devices, drug coatings and methods of maintaining the drug coatings thereon
US20020111590A1 (en) 2000-09-29 2002-08-15 Davila Luis A. Medical devices, drug coatings and methods for maintaining the drug coatings thereon
US6506437B1 (en) 2000-10-17 2003-01-14 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device having depots formed in a surface thereof
US6692498B1 (en) * 2000-11-27 2004-02-17 Linvatec Corporation Bioabsorbable, osteopromoting fixation plate
WO2002041931A2 (en) 2000-11-27 2002-05-30 Medtronic, Inc. Stents and methods for preparing stents
US6545097B2 (en) 2000-12-12 2003-04-08 Scimed Life Systems, Inc. Drug delivery compositions and medical devices containing block copolymer
US20020103526A1 (en) 2000-12-15 2002-08-01 Tom Steinke Protective coating for stent
US20020119179A1 (en) 2000-12-22 2002-08-29 Alireza Rezania Implantable biodegradable devices for musculoskeletal repair or regeneration
US7192604B2 (en) 2000-12-22 2007-03-20 Ethicon, Inc. Implantable biodegradable devices for musculoskeletal repair or regeneration
AU2002246785A1 (en) * 2000-12-28 2002-08-06 The Board Of Regents Of The University Of Nebraska Electrolytic deposition of coatings for prosthetic metals and alloys
US6596402B2 (en) 2000-12-29 2003-07-22 Kimberly-Clark Worldwide, Inc. Absorbent, lubricious coating and articles coated therewith
US6544582B1 (en) 2001-01-05 2003-04-08 Advanced Cardiovascular Systems, Inc. Method and apparatus for coating an implantable device
WO2002060507A1 (en) 2001-01-30 2002-08-08 Isotis S.A. A method for applying a bioactive coating on a medical device
US20020120333A1 (en) 2001-01-31 2002-08-29 Keogh James R. Method for coating medical device surfaces
US6558734B2 (en) 2001-02-09 2003-05-06 Medtronic, Inc. Methods for modifying surfaces of articles
DE10106546A1 (de) 2001-02-13 2002-08-22 Ethicon Gmbh Verfahren zum Herstellen eines medizinischen Implantats
WO2003047462A1 (en) 2001-03-12 2003-06-12 Clemson University Polysaccharide-based polmerizable hydrogels
US7771468B2 (en) 2001-03-16 2010-08-10 Angiotech Biocoatings Corp. Medicated stent having multi-layer polymer coating
EP1247537A1 (de) 2001-04-04 2002-10-09 Isotis B.V. Beschichtung für medizinische Vorrichtungen
FR2823675B1 (fr) 2001-04-19 2004-03-12 Inst Nat Sante Rech Med Biomateriaux avec recouvrements bioactifs
US6730324B2 (en) 2001-04-20 2004-05-04 The University Of British Columbia Biofunctional hydroxyapatite coatings and microspheres for in-situ drug encapsulation
US20040022853A1 (en) * 2001-04-26 2004-02-05 Control Delivery Systems, Inc. Polymer-based, sustained release drug delivery system
US20030004568A1 (en) 2001-05-04 2003-01-02 Concentric Medical Coated combination vaso-occlusive device
US7201940B1 (en) * 2001-06-12 2007-04-10 Advanced Cardiovascular Systems, Inc. Method and apparatus for thermal spray processing of medical devices
US6967234B2 (en) 2002-12-18 2005-11-22 Ethicon, Inc. Alkyd-lactone copolymers for medical applications
FI117667B (fi) 2001-07-05 2007-01-15 Univ Zuerich Farmaseuttinen koostumus, joka soveltuu käytettäväksi ortopediassa ja hammaslääketieteessä
US7316687B2 (en) * 2001-08-24 2008-01-08 Zimmer Technology, Inc. Blade plate and instruments
US6749639B2 (en) 2001-08-27 2004-06-15 Mayo Foundation For Medical Education And Research Coated prosthetic implant
US20040137066A1 (en) 2001-11-26 2004-07-15 Swaminathan Jayaraman Rationally designed therapeutic intravascular implant coating
US6669980B2 (en) 2001-09-18 2003-12-30 Scimed Life Systems, Inc. Method for spray-coating medical devices
EP1434571B1 (de) 2001-10-05 2005-05-11 SurModics, Inc. Beschichtungen mit immobilisierten partikeln sowie verwendungen derselben
CN100515504C (zh) 2001-10-12 2009-07-22 美国英佛曼公司 涂层,涂布体及其制造方法
DK1435877T3 (da) 2001-10-15 2009-08-03 Hemoteq Ag Overtrækning af stents for at forhindre restenose
US20030077310A1 (en) 2001-10-22 2003-04-24 Chandrashekhar Pathak Stent coatings containing HMG-CoA reductase inhibitors
US7722894B2 (en) 2001-10-22 2010-05-25 Massachusetts Institute Of Technology Biodegradable polymer
US7112361B2 (en) 2001-10-25 2006-09-26 Massachusetts Institute Of Technology Methods of making decomposable thin films of polyelectrolytes and uses thereof
US20040063654A1 (en) 2001-11-02 2004-04-01 Davis Mark E. Methods and compositions for therapeutic use of RNA interference
AU2002368202B2 (en) 2001-11-02 2008-06-05 Insert Therapeutics, Inc Methods and compositions for therapeutic use of RNA interference
US20030088307A1 (en) 2001-11-05 2003-05-08 Shulze John E. Potent coatings for stents
US7402318B2 (en) 2001-11-14 2008-07-22 Novartis Ag Medical devices having antimicrobial coatings thereon
US20030185870A1 (en) 2001-11-20 2003-10-02 Grinstaff Mark W. Interfacial biomaterials
US20030113478A1 (en) 2001-12-12 2003-06-19 Dang Mai Huong Surface coating method and coated device
JP2005522418A (ja) 2002-01-24 2005-07-28 スマート ドラッグ システムズ インコーポレイティド 徐放性医薬組成物
EP1469893A1 (de) 2002-02-01 2004-10-27 Sustech GmbH & Co. KG Sternformige prapolymere fur die herstellung ultradunner hydrogel-bildender beschichtungen
US20030153971A1 (en) 2002-02-14 2003-08-14 Chandru Chandrasekaran Metal reinforced biodegradable intraluminal stents
ATE348643T1 (de) 2002-02-15 2007-01-15 Cv Therapeutics Inc Polymerüberzug für medizinische vorrichtungen
EP1482841B1 (de) * 2002-03-14 2005-12-07 Yeung, Jeffery E. Nahtanker und adaptationsvorrichtung
WO2003080119A1 (en) 2002-03-26 2003-10-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Responsive biomedical composites
US7326426B2 (en) 2002-03-29 2008-02-05 Ethicon, Inc. Compositions and medical devices utilizing bioabsorbable liquid polymers
US20040051201A1 (en) 2002-04-11 2004-03-18 Greenhalgh Skott E. Coated stent and method for coating by treating an electrospun covering with heat or chemicals
US7008979B2 (en) 2002-04-30 2006-03-07 Hydromer, Inc. Coating composition for multiple hydrophilic applications
AU2003221582A1 (en) 2002-05-03 2003-11-17 Millenium Biologix Inc. Connective tissue stimulating peptides
EP1505931A1 (de) 2002-05-20 2005-02-16 Orbus Medical Technologies, Inc. Arznei-eluierende implantierbare medizinische vorrichtung
US7368125B2 (en) 2002-06-05 2008-05-06 Ethicon, Inc. Amphiphilic polymers for medical applications
US20040138695A1 (en) 2002-06-18 2004-07-15 Shu-Tung Li Coatings of implants
US6945448B2 (en) * 2002-06-18 2005-09-20 Zimmer Technology, Inc. Method for attaching a porous metal layer to a metal substrate
WO2004000276A1 (en) 2002-06-20 2003-12-31 Royer Biomedical, Inc. Resorbable matrices with coatings for delivery of bioactive compounds
US7049348B2 (en) 2002-07-06 2006-05-23 Kensey Nash Corporation Resorbable structure for treating and healing of tissue defects
US20060246103A1 (en) 2002-07-22 2006-11-02 Ralph James D Implantable devices for the delivery of therapeutic agents to an orthopaedic surgical site
AU2003268167B2 (en) 2002-08-20 2009-10-22 Exactech, Inc. Composition for the carrying and delivery of bone growth inducing material and methods for producing and applying the composition
EP1550477B1 (de) 2002-08-23 2015-11-04 National Cerebral and Cardiovascular Center Stent und verfahren zu seiner herstellung
US7438925B2 (en) 2002-08-26 2008-10-21 Biovention Holdings Ltd. Drug eluting coatings for medical implants
US20040044404A1 (en) 2002-08-30 2004-03-04 Stucke Sean M. Retention coatings for delivery systems
US7732535B2 (en) 2002-09-05 2010-06-08 Advanced Cardiovascular Systems, Inc. Coating for controlled release of drugs from implantable medical devices
US7862831B2 (en) 2002-10-09 2011-01-04 Synthasome, Inc. Method and material for enhanced tissue-biomaterial integration
US20040062882A1 (en) 2002-09-30 2004-04-01 Andrea Liebmann-Vinson Cell adhesion resisting surfaces
US8105652B2 (en) 2002-10-24 2012-01-31 Massachusetts Institute Of Technology Methods of making decomposable thin films of polyelectrolytes and uses thereof
US7348364B2 (en) 2002-10-31 2008-03-25 Poly-Med, Inc. Segmented copolyesters as compliant, absorbable coatings and sealants for vascular devices
US20050095267A1 (en) 2002-12-04 2005-05-05 Todd Campbell Nanoparticle-based controlled release polymer coatings for medical implants
AU2003286425A1 (en) 2002-12-05 2004-06-23 Cardio Incorporated Layered bioresorbable implant
US6872799B2 (en) 2002-12-18 2005-03-29 Ethicon, Inc. Functionalized polymers for medical applications
US6866860B2 (en) 2002-12-19 2005-03-15 Ethicon, Inc. Cationic alkyd polyesters for medical applications
US20040120982A1 (en) 2002-12-19 2004-06-24 Zanini Diana Biomedical devices with coatings attached via latent reactive components
US7736365B2 (en) * 2002-12-20 2010-06-15 Zimmer Technology, Inc. Provisional bone plate
US20040126405A1 (en) 2002-12-30 2004-07-01 Scimed Life Systems, Inc. Engineered scaffolds for promoting growth of cells
US20040147999A1 (en) 2003-01-24 2004-07-29 Kishore Udipi Stent with epoxy primer coating
US7314480B2 (en) 2003-02-27 2008-01-01 Boston Scientific Scimed, Inc. Rotating balloon expandable sheath bifurcation delivery
PL1603603T3 (pl) 2003-02-28 2015-07-31 Biointeractions Ltd System sieci polimerowych dla urządzeń medycznych oraz sposoby zastosowania
US7001421B2 (en) 2003-02-28 2006-02-21 Medtronic Vascular, Inc. Stent with phenoxy primer coating
US8088404B2 (en) 2003-03-20 2012-01-03 Medtronic Vasular, Inc. Biocompatible controlled release coatings for medical devices and related methods
WO2004085712A2 (en) 2003-03-24 2004-10-07 Penn State Research Foundation Multi-functional polymeric materials and their uses
US20040215313A1 (en) 2003-04-22 2004-10-28 Peiwen Cheng Stent with sandwich type coating
US8518097B2 (en) 2003-04-25 2013-08-27 Medtronic Vascular, Inc. Plasticized stent coatings
US20060105018A1 (en) 2004-11-17 2006-05-18 Epstein Samuel J Therapeutic driving layer for a medical device
US6923996B2 (en) 2003-05-06 2005-08-02 Scimed Life Systems, Inc. Processes for producing polymer coatings for release of therapeutic agent
BRPI0410377A (pt) 2003-05-16 2006-06-13 Blue Membranes Gmbh implantes medicinais revestidos bio-compatìveis
US7875293B2 (en) 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
US20040241234A1 (en) 2003-06-02 2004-12-02 Alpharma, Inc. Controlled release press-coated formulations of water-soluble active agents
US7662864B2 (en) 2003-06-04 2010-02-16 Rutgers, The State University Of New Jersey Solution polymerization processes to prepare a polymer that degrades to release a physiologically active agent
US7169404B2 (en) 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same
US7318944B2 (en) 2003-08-07 2008-01-15 Medtronic Vascular, Inc. Extrusion process for coating stents
US7790141B2 (en) 2003-08-11 2010-09-07 Pathak Holdings, Llc Radio-opaque compounds, compositions containing same and methods of their synthesis and use
JP2007507306A (ja) 2003-09-30 2007-03-29 ジンテーズ　アクチエンゲゼルシャフト　クール 整形外科用インプラントの抗微生物ヒアルロン酸被覆物
US20050129731A1 (en) 2003-11-03 2005-06-16 Roland Horres Biocompatible, biostable coating of medical surfaces
WO2005065079A2 (en) * 2003-11-10 2005-07-21 Angiotech International Ag Medical implants and fibrosis-inducing agents
US9114198B2 (en) 2003-11-19 2015-08-25 Advanced Cardiovascular Systems, Inc. Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
US20050112170A1 (en) 2003-11-20 2005-05-26 Hossainy Syed F. Coatings for implantable devices comprising polymers of lactic acid and methods for fabricating the same
US20070026043A1 (en) 2003-11-20 2007-02-01 Angiotech International Ag Medical devices combined with diblock copolymer compositions
US7807722B2 (en) 2003-11-26 2010-10-05 Advanced Cardiovascular Systems, Inc. Biobeneficial coating compositions and methods of making and using thereof
WO2005058199A1 (en) 2003-12-16 2005-06-30 Avery Dennison Corporation Electrostatically self-assembled antimicrobial coating for medical applications
US8309112B2 (en) 2003-12-24 2012-11-13 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices comprising hydrophilic substances and methods for fabricating the same
CA2552241C (en) 2003-12-30 2013-10-01 Durect Corporation Co-polymeric devices for controlled release of active agents
US7402170B2 (en) 2003-12-30 2008-07-22 Scimed Life Systems, Inc. Crimp and weld wire connection
US7284401B2 (en) 2004-01-12 2007-10-23 Boston Scientific Scimed, Inc. Stent reducing system and device
US7922753B2 (en) 2004-01-13 2011-04-12 Boston Scientific Scimed, Inc. Bifurcated stent delivery system
US7976858B2 (en) 2004-01-13 2011-07-12 The Hospital For Special Surgery Drug delivery to a joint
US20050180919A1 (en) 2004-02-12 2005-08-18 Eugene Tedeschi Stent with radiopaque and encapsulant coatings
US8012192B2 (en) 2004-02-18 2011-09-06 Boston Scientific Scimed, Inc. Multi-stent delivery system
US7225518B2 (en) 2004-02-23 2007-06-05 Boston Scientific Scimed, Inc. Apparatus for crimping a stent assembly
US7744619B2 (en) 2004-02-24 2010-06-29 Boston Scientific Scimed, Inc. Rotatable catheter assembly
EP1729675A4 (de) 2004-03-05 2011-05-18 Univ Columbia Mehrphasiges biologisch abbaubares und osteointegratives kompositgerüst für die biologische fixierung von skelettmuskelweichgewebe an knochen
US7744644B2 (en) 2004-03-19 2010-06-29 Boston Scientific Scimed, Inc. Medical articles having regions with polyelectrolyte multilayer coatings for regulating drug release
US20050208093A1 (en) 2004-03-22 2005-09-22 Thierry Glauser Phosphoryl choline coating compositions
CA2560507C (en) 2004-03-26 2011-08-16 Surmodics, Inc. Composition and method for preparing biocompatible surfaces
US20050214339A1 (en) 2004-03-29 2005-09-29 Yiwen Tang Biologically degradable compositions for medical applications
CN1964748A (zh) 2004-04-06 2007-05-16 苏莫迪克斯公司 用于生物活性剂的涂料组合物
US8293890B2 (en) 2004-04-30 2012-10-23 Advanced Cardiovascular Systems, Inc. Hyaluronic acid based copolymers
US7820732B2 (en) 2004-04-30 2010-10-26 Advanced Cardiovascular Systems, Inc. Methods for modulating thermal and mechanical properties of coatings on implantable devices
JP5026956B2 (ja) 2004-05-12 2012-09-19 サーモディクス，インコーポレイティド 医療用具のための天然生分解性多糖コーティング
US9561309B2 (en) 2004-05-27 2017-02-07 Advanced Cardiovascular Systems, Inc. Antifouling heparin coatings
US20050271700A1 (en) 2004-06-03 2005-12-08 Desnoyer Jessica R Poly(ester amide) coating composition for implantable devices
JP4874970B2 (ja) 2004-06-07 2012-02-15 ジンテス ゲゼルシャフト ミット ベシュレンクテル ハフツング センサ付き整形外科用インプラント
US7216689B2 (en) * 2004-06-14 2007-05-15 United Technologies Corporation Investment casting
US7794490B2 (en) 2004-06-22 2010-09-14 Boston Scientific Scimed, Inc. Implantable medical devices with antimicrobial and biodegradable matrices
US20060018948A1 (en) 2004-06-24 2006-01-26 Guire Patrick E Biodegradable implantable medical devices, methods and systems
US8696564B2 (en) 2004-07-09 2014-04-15 Cardiac Pacemakers, Inc. Implantable sensor with biocompatible coating for controlling or inhibiting tissue growth
US20060009839A1 (en) 2004-07-12 2006-01-12 Scimed Life Systems, Inc. Composite vascular graft including bioactive agent coating and biodegradable sheath
WO2006127694A2 (en) 2004-07-13 2006-11-30 Dexcom, Inc. Analyte sensor
US20060025848A1 (en) 2004-07-29 2006-02-02 Jan Weber Medical device having a coating layer with structural elements therein and method of making the same
WO2006020616A1 (en) 2004-08-13 2006-02-23 Reva Medical, Inc. Inherently radiopaque bioresorbable polymers for multiple uses
US20060039950A1 (en) 2004-08-23 2006-02-23 Zhengrong Zhou Multi-functional biocompatible coatings for intravascular devices
US8119153B2 (en) 2004-08-26 2012-02-21 Boston Scientific Scimed, Inc. Stents with drug eluting coatings
WO2006031532A2 (en) 2004-09-10 2006-03-23 Surmodics, Inc. Methods, devices, and coatings for controlled active agent release
WO2006037049A2 (en) 2004-09-28 2006-04-06 Atrium Medical Corporation Application of a coating on a medical device
US20060173458A1 (en) 2004-10-07 2006-08-03 Micah Forstein Bone fracture fixation system
AU2005302484A1 (en) 2004-10-28 2006-05-11 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
US20060198868A1 (en) 2005-01-05 2006-09-07 Dewitt David M Biodegradable coating compositions comprising blends
US7988987B2 (en) 2005-01-25 2011-08-02 Boston Scientific Scimed, Inc. Medical devices containing crazed polymeric release regions for drug delivery
CA2535938C (en) 2005-02-10 2014-11-25 Cardinal Health 529, Llc Biodegradable medical devices with enhanced mechanical strength and pharmacological functions
US8221504B2 (en) 2005-02-23 2012-07-17 Wright Medical Technology, Inc. Coating an implant for increased bone in-growth
US8728463B2 (en) 2005-03-11 2014-05-20 Wake Forest University Health Science Production of tissue engineered digits and limbs
US7517914B2 (en) 2005-04-04 2009-04-14 Boston Scientificscimed, Inc. Controlled degradation materials for therapeutic agent delivery
US20060233941A1 (en) 2005-04-15 2006-10-19 Boston Scientific Scimed, Inc. Method of coating a medical device utilizing an ion-based thin film deposition technique, a system for coating a medical device, and a medical device produced by the method
EP1874222A4 (de) 2005-04-18 2012-08-22 Univ Duke Dreidimensionale fasergerüste für gewebe-engineering
US8414907B2 (en) 2005-04-28 2013-04-09 Warsaw Orthopedic, Inc. Coatings on medical implants to guide soft tissue healing
US9119901B2 (en) 2005-04-28 2015-09-01 Warsaw Orthopedic, Inc. Surface treatments for promoting selective tissue attachment to medical impants
US20060251824A1 (en) 2005-05-05 2006-11-09 Boulais Dennis R Coating of medical devices with solids
JP4863655B2 (ja) 2005-06-17 2012-01-25 国立大学法人 東京医科歯科大学 細胞含有シート
US20060286071A1 (en) 2005-06-21 2006-12-21 Epstein Samuel J Therapeutic pastes for medical device coating
WO2007001624A2 (en) 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
US8367096B2 (en) 2005-07-19 2013-02-05 Boston Scientific Scimed, Inc. Polymers having covalently bound therapeutic agents
JP5908664B2 (ja) 2005-07-20 2016-04-26 サーモディクス，インコーポレイティド ポリマーコーティング及び細胞接着方法
US7824414B2 (en) 2005-07-22 2010-11-02 Kensey Nash Corporation System and devices for the repair of a vertebral disc defect
WO2007014241A1 (en) 2005-07-25 2007-02-01 Boston Scientific Scimed, Inc. Pelvic floor repair system
WO2007025059A1 (en) 2005-08-26 2007-03-01 Surmodics, Inc. Silane coating compositions, coating systems, and methods
US7185695B1 (en) * 2005-09-01 2007-03-06 United Technologies Corporation Investment casting pattern manufacture
WO2007044229A2 (en) 2005-09-28 2007-04-19 Calcitec, Inc. Surface treatments for calcium phosphate-based implants
US8403985B2 (en) * 2005-11-02 2013-03-26 Zimmer, Inc. Joint spacer implant
US8187660B2 (en) 2006-01-05 2012-05-29 Howmedica Osteonics Corp. Method for fabricating a medical implant component and such component
US20070191848A1 (en) * 2006-02-01 2007-08-16 Zimmer Technology, Inc. Hydrogel bone plate spacer
KR20090102789A (ko) * 2006-12-06 2009-09-30 퓨전 멀티시스템즈, 인크.(디비에이 퓨전-아이오) 프로그레시브 ｒａｉｄ를 이용한 데이터 저장 장치, 시스템 및 방법
US20080183172A1 (en) * 2007-01-26 2008-07-31 Zimmer Technology, Inc. Retention feature for plate guides
US20080234749A1 (en) * 2007-01-26 2008-09-25 Zimmer Technology, Inc. Bone plate providing threaded locking head screw capture
US8343155B2 (en) * 2008-05-15 2013-01-01 Zimmer, Inc. Cable button

Also Published As

Publication number Publication date
EP2005978A1 (de) 2008-12-24
JP2009011825A (ja) 2009-01-22
EP2005978B1 (de) 2011-09-14
CA2635320A1 (en) 2008-12-19
US8309521B2 (en) 2012-11-13
US20080317812A1 (en) 2008-12-25

Similar Documents

Publication Publication Date Title
DE602007011908D1 (de) Verwendung von gpr119-rezeptoragonisten zur vermehrung der knochenmasse und zur behandlung von osteoporose sowie kombinationstherapie dafür
WO2006116559A3 (en) Coatings on medical implants to guide soft tissue healing
DE602006012039D1 (de) Verfahren zur sterilisierung einer medizinischen vorrichtung mit hydrophiler beschichtung
DE112007003309A5 (de) Knochenimplantat sowie Set zur Herstellung von Knochenimplantaten
DE602004013257D1 (de) Implantate mit lebender Gewebe zur Reparatur von Gewebeschäden oder Gewebedefekten
SE9901973L (sv) Implantat för applicering i ben och förfarande och användning vid sådant implantat
DE602004031134D1 (de) Pharmazeutische zusammensetzungen und verfahren zur verwendung von levodopa und carbidopa
ATE523248T1 (de) Oberflächenbehandeltes calciumcarbonat und dessen verwendung zur abwasserbehandlung
BRPI0811668A2 (pt) "método de ativação da atividade osteogênica ou condrogênica em um sítio em um indivíduo com necessidade do mesmo, método de tratamento de uma deficiência de osso ou de cartilagem em um indivíduo, uso de um aparelho de pressão reduzida, composição para tratamento de uma deficiência de osso ou de cartilagem e uso de um aparelho de pressão reduzida e de uma estrutura de suporte biocompatível"
EP1931418A4 (de) Elektrode zur stimulation von knochenwuchs, gewebeheilung und/oder schmerzkontrolle und anwendungsverfahren
ATE438346T1 (de) Implantat zur dynamischen fixation einer korrekturosteotomie
ATE487441T1 (de) Gerät zur erzeugung des zugspannungsinduzierten wachstums von biologischem gewebe
ATE402663T1 (de) Flächiges implantat
ATE493157T1 (de) Implantate mit befestigten silylierten therapeutischen mitteln
TW200633733A (en) Biomaterials for guided tissue regeneration and drug delivery
DE602005025682D1 (de) Dentalfüllstoffe und zusammensetzungen mit phosphatsalzen
EP1789088A4 (de) Verfahren zur durchführung von medizinischen verfahren zur förderung des knochenwachstums, verfahren zur herstellung von zusammensetzungen zur förderung des knochenwachstums und gerät zur verwendung bei solchen verfahren
WO2009066283A3 (en) Calcium-mediated effects of coral and methods of use thereof
BRPI0419111A (pt) dispositivo de implante no osso revestido com ácido hialurÈnico
WO2007060507A3 (en) Lateral implant system and apparatus for reduction and reconstruction
WO2008130989A3 (en) Prosthetic implants
BR112012026636A2 (pt) implantes médicos com hidrofilicidade aumentada
EP1744766A4 (de) Zusammensetzung zur stimulierung des knochenwachstums und differenzierung und isolationsverfahren dafür
WO2014053906A8 (en) The application of stem cells in the orthodontic maxillary expansion
WO2012158208A3 (en) Implant and fastener fixation devices and delivery instrumentation

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties