ATE524236T1 - Hybridisierungsvorrichtung - Google Patents

Hybridisierungsvorrichtung

Info

Publication number
ATE524236T1
ATE524236T1 AT03713303T AT03713303T ATE524236T1 AT E524236 T1 ATE524236 T1 AT E524236T1 AT 03713303 T AT03713303 T AT 03713303T AT 03713303 T AT03713303 T AT 03713303T AT E524236 T1 ATE524236 T1 AT E524236T1
Authority
AT
Austria
Prior art keywords
chambers
substrate
hybridization device
pliable
probes
Prior art date
Application number
AT03713303T
Other languages
English (en)
Inventor
Tim Patno
Mark Fisher
George Aye
Tom Westberg
Original Assignee
Nanosphere Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nanosphere Inc filed Critical Nanosphere Inc
Application granted granted Critical
Publication of ATE524236T1 publication Critical patent/ATE524236T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50853—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/505—Flexible containers without fluid transport within
    • B01L3/5055—Hinged, e.g. opposable surfaces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT03713303T 2002-01-28 2003-01-27 Hybridisierungsvorrichtung ATE524236T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US35234602P 2002-01-28 2002-01-28
US42631602P 2002-11-14 2002-11-14
PCT/US2003/002486 WO2003064045A1 (en) 2002-01-28 2003-01-27 Hybridization device and method

Publications (1)

Publication Number Publication Date
ATE524236T1 true ATE524236T1 (de) 2011-09-15

Family

ID=27669056

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03713303T ATE524236T1 (de) 2002-01-28 2003-01-27 Hybridisierungsvorrichtung

Country Status (7)

Country Link
US (2) US7163823B2 (de)
EP (1) EP1487580B1 (de)
JP (1) JP2005515773A (de)
AT (1) ATE524236T1 (de)
AU (1) AU2003217261B2 (de)
CA (1) CA2474020A1 (de)
WO (1) WO2003064045A1 (de)

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US6582921B2 (en) * 1996-07-29 2003-06-24 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses thereof
US20030096321A1 (en) * 1999-05-19 2003-05-22 Jose Remacle Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips
ATE423975T1 (de) * 2001-08-03 2009-03-15 Nanosphere Inc Nanopartikelabbildungssystem und -verfahren
US20040146917A1 (en) * 2001-08-03 2004-07-29 Nanosphere, Inc. Nanoparticle imaging system and method
US7163823B2 (en) * 2002-01-28 2007-01-16 Nanosphere, Inc. DNA hybridization device and method
US7341865B1 (en) * 2002-10-25 2008-03-11 Perlegen Sciences, Inc. Liquid delivery devices and methods
US7011794B2 (en) * 2002-11-25 2006-03-14 Immunivest Corporation Upon a cartridge for containing a specimen sample for optical analysis
US20040126766A1 (en) * 2002-12-26 2004-07-01 Amorese Douglas A. Breakaway seal for processing a subarray of an array
DE10306018A1 (de) * 2003-02-13 2004-09-09 Siemens Ag Analyse- und Diagnostikinstrument
ES2614425T3 (es) 2004-01-08 2017-05-31 Dako Denmark A/S Aparato y métodos para el procesamiento de muestras biológicas y un depósito para los mismos
JP2008507296A (ja) * 2004-07-26 2008-03-13 ナノスフェアー　インコーポレイテッド 混合培養物中でメチシリン耐性黄色ブドウ球菌とメチシリン感受性黄色ブドウ球菌とを区別する方法
EP1835019A1 (de) * 2004-07-29 2007-09-19 Ngk Insulators, Ltd. Hybridisierungsvorrichtung und verfahren
US7524672B2 (en) * 2004-09-22 2009-04-28 Sandia Corporation Microfluidic microarray systems and methods thereof
KR20070122465A (ko) * 2005-03-25 2007-12-31 니뽄 가이시 가부시키가이샤 프로브 어레이 및 프로브 어레이의 제조 방법
EP2004328B1 (de) * 2006-03-09 2014-06-04 Agency for Science, Technology and Research Verfahren zur durchführung einer reaktion in einem tröpfchen
WO2008063135A1 (en) * 2006-11-24 2008-05-29 Agency For Science, Technology And Research Apparatus for processing a sample in a liquid droplet and method of using the same
US9874501B2 (en) 2006-11-24 2018-01-23 Curiox Biosystems Pte Ltd. Use of chemically patterned substrate for liquid handling, chemical and biological reactions
WO2013114217A1 (en) 2012-02-05 2013-08-08 Curiox Biosystems Pte Ltd. Array plates and methods for making and using same
US10725020B2 (en) 2007-11-14 2020-07-28 Curiox Biosystems Pte Ltd. High throughput miniaturized assay system and methods
WO2009091535A1 (en) * 2008-01-15 2009-07-23 Empire Genomics Llc Method and device for dual array hybridization karyotype analysis
US8784752B2 (en) 2009-04-17 2014-07-22 Curiox Biosystems Pte Ltd Use of chemically patterned substrate for liquid handling, chemical and biological reactions
US9878328B2 (en) 2010-07-23 2018-01-30 Curiox Biosystems Pte Ltd. Apparatus and method for multiple reactions in small volumes
IT1403765B1 (it) * 2011-01-31 2013-10-31 Fond G B Bietti Per Lo Studio E La Ricerca In Oftalmologia Onlus Irccs Dispositivo per l'analisi di campioni biologici.
US9557318B2 (en) 2013-07-09 2017-01-31 Curiox Biosystems Pte Ltd. Array plates for washing samples
US9827567B2 (en) 2014-04-22 2017-11-28 Nanosphere, Inc. Diagnostic cartridges having flexible seals
US10545139B2 (en) 2015-06-16 2020-01-28 Curiox Biosystems Pte Ltd. Methods and devices for performing biological assays using magnetic components
CN118558386A (zh) 2017-04-05 2024-08-30 科睿思生物科技(私人)有限公司 用于清洗阵列板上的样品的方法、设备和装置
TWI738328B (zh) 2017-09-28 2021-09-01 美商伊路米納有限公司 流體施配器總成與用於將流體施配至流體匣中的方法
EP3820610A1 (de) 2018-07-12 2021-05-19 Luminex Corporation Systeme und verfahren zur durchführung variabler probenvorbereitung und analyseverfahren

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US3745091A (en) 1970-11-18 1973-07-10 Miles Lab Biological reaction chamber apparatus
US5346672A (en) * 1989-11-17 1994-09-13 Gene Tec Corporation Devices for containing biological specimens for thermal processing
US5192503A (en) 1990-05-23 1993-03-09 Mcgrath Charles M Probe clip in situ assay apparatus
US5587128A (en) * 1992-05-01 1996-12-24 The Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification devices
US6258325B1 (en) 1993-04-19 2001-07-10 Ashok Ramesh Sanadi Method and apparatus for preventing cross-contamination of multi-well test plates
US5512492A (en) * 1993-05-18 1996-04-30 University Of Utah Research Foundation Waveguide immunosensor with coating chemistry providing enhanced sensitivity
US5472672A (en) * 1993-10-22 1995-12-05 The Board Of Trustees Of The Leland Stanford Junior University Apparatus and method for polymer synthesis using arrays
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US5605813A (en) 1995-06-06 1997-02-25 Becton, Dickinson And Company Culture slide assembly
ATE194387T1 (de) 1995-11-14 2000-07-15 Loders Croklaan Bv Prozess für die präparation von substanzen mit hohem gehalt an isomeren von konjugierte linölsäure
US6143496A (en) * 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US6159368A (en) * 1998-10-29 2000-12-12 The Perkin-Elmer Corporation Multi-well microfiltration apparatus
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US6258593B1 (en) * 1999-06-30 2001-07-10 Agilent Technologies Inc. Apparatus for conducting chemical or biochemical reactions on a solid surface within an enclosed chamber
AU2001244687A1 (en) * 2000-07-10 2002-01-21 Wakunaga Pharmaceutical Co., Ltd Micro-array
US20020048754A1 (en) 2000-10-24 2002-04-25 Lockhart David J. Apparatus and method for processing multiple arrays of biological probes
US6905816B2 (en) 2000-11-27 2005-06-14 Intelligent Medical Devices, Inc. Clinically intelligent diagnostic devices and methods
EP1524028B1 (de) * 2001-05-25 2008-09-24 Tecan Trading AG Vorrichtung und Verfahrenseinheit zum Bereitstellen eines Hybridisierraums
US6514750B2 (en) 2001-07-03 2003-02-04 Pe Corporation (Ny) PCR sample handling device
US6475774B1 (en) 2001-09-18 2002-11-05 Hemant Gupta Reaction plate sealing means
US7163823B2 (en) * 2002-01-28 2007-01-16 Nanosphere, Inc. DNA hybridization device and method

Also Published As

Publication number Publication date
US7163823B2 (en) 2007-01-16
EP1487580A1 (de) 2004-12-22
US20030224505A1 (en) 2003-12-04
US20070134785A1 (en) 2007-06-14
JP2005515773A (ja) 2005-06-02
EP1487580A4 (de) 2006-04-19
EP1487580B1 (de) 2011-09-14
AU2003217261B2 (en) 2007-03-22
CA2474020A1 (en) 2003-08-07
WO2003064045A1 (en) 2003-08-07

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Legal Events

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