ATE525355T1 - 1-ä(4-äbenzoyl(methyl)aminoü-3- (phenyl)butylüazetidinderivate zur behandlung von gastrointestinalen erkrankungen 1 - Google Patents
1-ä(4-äbenzoyl(methyl)aminoü-3- (phenyl)butylüazetidinderivate zur behandlung von gastrointestinalen erkrankungen 1Info
- Publication number
- ATE525355T1 ATE525355T1 AT07748146T AT07748146T ATE525355T1 AT E525355 T1 ATE525355 T1 AT E525355T1 AT 07748146 T AT07748146 T AT 07748146T AT 07748146 T AT07748146 T AT 07748146T AT E525355 T1 ATE525355 T1 AT E525355T1
- Authority
- AT
- Austria
- Prior art keywords
- äbenzoyl
- butyluacetidine
- aminoü
- phenyl
- derivatives
- Prior art date
Links
- 208000018522 Gastrointestinal disease Diseases 0.000 title 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80157706P | 2006-05-18 | 2006-05-18 | |
| PCT/SE2007/000482 WO2007136324A1 (en) | 2006-05-18 | 2007-05-16 | 1- [ (4- [benzoyl (methyl) amino] -3- (phenyl) butyl] azetidine derivatives for the treatment of gastrointestinal disorders 1 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE525355T1 true ATE525355T1 (de) | 2011-10-15 |
Family
ID=38723558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07748146T ATE525355T1 (de) | 2006-05-18 | 2007-05-16 | 1-ä(4-äbenzoyl(methyl)aminoü-3- (phenyl)butylüazetidinderivate zur behandlung von gastrointestinalen erkrankungen 1 |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US8106208B2 (de) |
| EP (1) | EP2024354B1 (de) |
| JP (1) | JP5196381B2 (de) |
| KR (1) | KR101429779B1 (de) |
| CN (1) | CN101472910B (de) |
| AR (1) | AR060956A1 (de) |
| AT (1) | ATE525355T1 (de) |
| AU (1) | AU2007253666B2 (de) |
| BR (1) | BRPI0712405A2 (de) |
| CA (1) | CA2652443C (de) |
| DK (1) | DK2024354T3 (de) |
| ES (1) | ES2373335T3 (de) |
| IL (1) | IL195197A (de) |
| MX (1) | MX2008014686A (de) |
| MY (1) | MY147474A (de) |
| NO (1) | NO20084674L (de) |
| PL (1) | PL2024354T3 (de) |
| PT (1) | PT2024354E (de) |
| RU (1) | RU2439067C2 (de) |
| TW (1) | TW200813006A (de) |
| UY (1) | UY30356A1 (de) |
| WO (1) | WO2007136324A1 (de) |
| ZA (1) | ZA200809909B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR057828A1 (es) * | 2005-09-29 | 2007-12-19 | Astrazeneca Ab | Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica |
| US20100168103A1 (en) * | 2006-09-14 | 2010-07-01 | Neuromed Pharmaceuticals Ltd. | Diaryl piperidine compounds as calcium channel blockers |
| US20110021534A1 (en) | 2007-03-08 | 2011-01-27 | Albireo Ab | 2 -substituted- 3 -phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel disease |
| EP2300422B1 (de) * | 2008-05-08 | 2014-11-05 | Evotec AG | Azetidine als antagonisten des histamin-h3-rezeptors |
| KR20130142137A (ko) * | 2010-10-22 | 2013-12-27 | 얀센 파마슈티카 엔.브이. | 모노아실글리세롤 리파아제 억제제로서의 피페리딘-4-일-아제티딘 다이아미드 |
| JP2014528427A (ja) * | 2011-09-30 | 2014-10-27 | ヤンセン ファーマシューティカ エヌ.ベー. | (1−(4−フルオロフェニル)−1h−インドール−5−イル)−(3−(4−(チアゾール−2−カルボニル)ピペラジン−1−イル)アゼチジン−1−イル)メタノンの結晶性塩酸塩、並びに疼痛及び代謝障害の処置におけるその使用 |
| CN104529833B (zh) * | 2014-12-10 | 2016-04-20 | 广东东阳光药业有限公司 | 取代的环丁烷羧酸类化合物及其用途 |
| KR102476938B1 (ko) | 2017-12-07 | 2022-12-13 | 기초과학연구원 | 핫전자 기반의 산화물-금속 하이브리드 역촉매 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9310066D0 (en) | 1993-05-17 | 1993-06-30 | Zeneca Ltd | Alkyl substituted heterocycles |
| GB9310713D0 (en) | 1993-05-24 | 1993-07-07 | Zeneca Ltd | Aryl substituted heterocycles |
| GB9317104D0 (en) * | 1993-08-17 | 1993-09-29 | Zeneca Ltd | Therapeutic heterocycles |
| GB9322643D0 (en) | 1993-11-03 | 1993-12-22 | Zeneca Ltd | Lactam derivatives |
| GB9325074D0 (en) | 1993-12-07 | 1994-02-02 | Zeneca Ltd | Bicyclic heterocycles |
| TW432061B (en) * | 1994-08-09 | 2001-05-01 | Pfizer Res & Dev | Lactams |
| GB9502644D0 (en) | 1995-02-10 | 1995-03-29 | Zeneca Ltd | Heterocyclic derivatives |
| GB9600235D0 (en) | 1996-01-05 | 1996-03-06 | Pfizer Ltd | Therapeutic agents |
| GB9601202D0 (en) | 1996-01-22 | 1996-03-20 | Pfizer Ltd | Piperidones |
| GB9601680D0 (en) | 1996-01-27 | 1996-03-27 | Pfizer Ltd | Therapeutic agents |
| GB9601697D0 (en) | 1996-01-27 | 1996-03-27 | Pfizer Ltd | Therapeutic agents |
| GB9714129D0 (en) | 1997-07-04 | 1997-09-10 | Pfizer Ltd | Azetidines |
| GB9812037D0 (en) | 1998-06-04 | 1998-07-29 | Pfizer Ltd | Piperidones |
| US6365602B1 (en) | 1998-07-10 | 2002-04-02 | Astra Zeneca Ab | N-substituted naphthalene carboxamides as neurokinin-receptor antagonists |
| GB9922519D0 (en) | 1998-10-07 | 1999-11-24 | Zeneca Ltd | Compounds |
| GB9922521D0 (en) | 1998-10-07 | 1999-11-24 | Zeneca Ltd | Compounds |
| GB9924141D0 (en) | 1998-10-30 | 1999-12-15 | Zeneca Ltd | Treatment of gastric asthma |
| GB9826941D0 (en) | 1998-12-09 | 1999-02-03 | Zeneca Pharmaceuticals | Compounds |
| SE0004827D0 (sv) | 2000-12-22 | 2000-12-22 | Astrazeneca Ab | Therapeutic compounds |
| SE0103795D0 (sv) | 2001-11-02 | 2001-11-02 | Astrazeneca Ab | Compounds and method for the treatment of överactive bladder |
| TW200508221A (en) * | 2003-06-13 | 2005-03-01 | Astrazeneca Ab | New azetidine compounds |
| EP1899318A4 (de) * | 2005-06-23 | 2010-03-17 | Astrazeneca Ab | Neue azetidinderivate als neurokininrezeptorantagonisten zur behandlung von magen-darm-erkrankungen |
| EP1899326A4 (de) * | 2005-06-23 | 2009-12-16 | Albireo Ab | Neue azetidinderivate als neurokininrezeptorantagonisten zur behandlung von magen-darm-erkrankungen |
| AR056087A1 (es) * | 2005-09-29 | 2007-09-19 | Astrazeneca Ab | Derivados de azetidina como antagonistas de receptores de neuroquina nk |
| AR057828A1 (es) * | 2005-09-29 | 2007-12-19 | Astrazeneca Ab | Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica |
-
2007
- 2007-05-11 US US11/747,322 patent/US8106208B2/en not_active Expired - Fee Related
- 2007-05-14 TW TW096117067A patent/TW200813006A/zh unknown
- 2007-05-16 PL PL07748146T patent/PL2024354T3/pl unknown
- 2007-05-16 BR BRPI0712405-8A patent/BRPI0712405A2/pt not_active IP Right Cessation
- 2007-05-16 ES ES07748146T patent/ES2373335T3/es active Active
- 2007-05-16 PT PT07748146T patent/PT2024354E/pt unknown
- 2007-05-16 WO PCT/SE2007/000482 patent/WO2007136324A1/en not_active Ceased
- 2007-05-16 UY UY30356A patent/UY30356A1/es unknown
- 2007-05-16 RU RU2008149927/04A patent/RU2439067C2/ru not_active IP Right Cessation
- 2007-05-16 CA CA2652443A patent/CA2652443C/en not_active Expired - Fee Related
- 2007-05-16 AR ARP070102113A patent/AR060956A1/es not_active Application Discontinuation
- 2007-05-16 AT AT07748146T patent/ATE525355T1/de not_active IP Right Cessation
- 2007-05-16 AU AU2007253666A patent/AU2007253666B2/en not_active Ceased
- 2007-05-16 JP JP2009510922A patent/JP5196381B2/ja not_active Expired - Fee Related
- 2007-05-16 KR KR1020087029057A patent/KR101429779B1/ko not_active Expired - Fee Related
- 2007-05-16 CN CN200780022773.8A patent/CN101472910B/zh not_active Expired - Fee Related
- 2007-05-16 DK DK07748146.3T patent/DK2024354T3/da active
- 2007-05-16 EP EP07748146A patent/EP2024354B1/de not_active Not-in-force
- 2007-05-16 MX MX2008014686A patent/MX2008014686A/es active IP Right Grant
-
2008
- 2008-11-06 NO NO20084674A patent/NO20084674L/no not_active Application Discontinuation
- 2008-11-10 IL IL195197A patent/IL195197A/en not_active IP Right Cessation
- 2008-11-11 MY MYPI20084521A patent/MY147474A/en unknown
- 2008-11-20 ZA ZA200809909A patent/ZA200809909B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009537516A (ja) | 2009-10-29 |
| NO20084674L (no) | 2009-01-29 |
| US20070270398A1 (en) | 2007-11-22 |
| PL2024354T3 (pl) | 2012-02-29 |
| EP2024354B1 (de) | 2011-09-21 |
| HK1121758A1 (en) | 2009-04-30 |
| AU2007253666A1 (en) | 2007-11-29 |
| JP5196381B2 (ja) | 2013-05-15 |
| IL195197A (en) | 2013-10-31 |
| DK2024354T3 (da) | 2012-01-16 |
| RU2008149927A (ru) | 2010-06-27 |
| CN101472910B (zh) | 2014-03-26 |
| TW200813006A (en) | 2008-03-16 |
| BRPI0712405A2 (pt) | 2012-10-16 |
| CN101472910A (zh) | 2009-07-01 |
| AU2007253666B2 (en) | 2012-03-15 |
| RU2439067C2 (ru) | 2012-01-10 |
| KR101429779B1 (ko) | 2014-08-19 |
| CA2652443A1 (en) | 2007-11-29 |
| UY30356A1 (es) | 2008-01-02 |
| MX2008014686A (es) | 2009-02-10 |
| CA2652443C (en) | 2014-01-14 |
| WO2007136324A1 (en) | 2007-11-29 |
| IL195197A0 (en) | 2009-08-03 |
| US8106208B2 (en) | 2012-01-31 |
| EP2024354A4 (de) | 2009-11-11 |
| MY147474A (en) | 2012-12-14 |
| PT2024354E (pt) | 2011-12-19 |
| ZA200809909B (en) | 2009-08-26 |
| ES2373335T3 (es) | 2012-02-02 |
| AR060956A1 (es) | 2008-07-23 |
| EP2024354A1 (de) | 2009-02-18 |
| KR20090018926A (ko) | 2009-02-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |