ATE526045T1 - Materialien für ophthalmische und otorhinolaryngologische geräte mit geringer haftung - Google Patents

Materialien für ophthalmische und otorhinolaryngologische geräte mit geringer haftung

Info

Publication number
ATE526045T1
ATE526045T1 AT07813161T AT07813161T ATE526045T1 AT E526045 T1 ATE526045 T1 AT E526045T1 AT 07813161 T AT07813161 T AT 07813161T AT 07813161 T AT07813161 T AT 07813161T AT E526045 T1 ATE526045 T1 AT E526045T1
Authority
AT
Austria
Prior art keywords
ophthalmic
materials
low adhesion
otorhinolaryngological devices
otorhinolaryngological
Prior art date
Application number
AT07813161T
Other languages
English (en)
Inventor
Diana M Cordova
Mutlu Karakelle
Chance Lehman
Douglas C Schlueter
Weinschenk, Iii
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE526045T1 publication Critical patent/ATE526045T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/16—Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A61F2/1616—Pseudo-accommodative, e.g. multifocal or enabling monovision
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/16—Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
AT07813161T 2006-07-21 2007-07-20 Materialien für ophthalmische und otorhinolaryngologische geräte mit geringer haftung ATE526045T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83247806P 2006-07-21 2006-07-21
PCT/US2007/073984 WO2008011566A2 (en) 2006-07-21 2007-07-20 Low-tack ophthalmic and otorhinolaryngological device materials

Publications (1)

Publication Number Publication Date
ATE526045T1 true ATE526045T1 (de) 2011-10-15

Family

ID=38802372

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07813161T ATE526045T1 (de) 2006-07-21 2007-07-20 Materialien für ophthalmische und otorhinolaryngologische geräte mit geringer haftung

Country Status (19)

Country Link
US (1) US7585900B2 (de)
EP (1) EP2043699B1 (de)
JP (1) JP5177823B2 (de)
KR (1) KR101403316B1 (de)
CN (1) CN101563115B (de)
AR (1) AR062015A1 (de)
AT (1) ATE526045T1 (de)
AU (1) AU2007275227B2 (de)
BR (1) BRPI0715431B8 (de)
CA (1) CA2657633C (de)
ES (1) ES2371576T3 (de)
IL (1) IL196467A (de)
MX (1) MX2009000821A (de)
NO (1) NO20090793L (de)
NZ (1) NZ574812A (de)
RU (1) RU2433837C2 (de)
TW (1) TWI399228B (de)
WO (1) WO2008011566A2 (de)
ZA (1) ZA200900319B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201006846A (en) * 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
US8058323B2 (en) * 2006-07-21 2011-11-15 Novartis Ag Low-tack ophthalmic and otorhinolaryngological device materials
US7714039B2 (en) * 2006-07-21 2010-05-11 Alcon, Inc. Low-tack ophthalmic and otorhinolaryngological device materials
TW200916531A (en) * 2007-08-09 2009-04-16 Alcon Inc Ophthalmic lens materials containing chromophores that absorb both UV and short wavelength visible light
US8148445B1 (en) 2009-01-14 2012-04-03 Novartis Ag Ophthalmic and otorhinolaryngological device materials containing a multi-arm PEG macromer
US8109997B2 (en) * 2009-01-18 2012-02-07 Eyeon Medical Ltd. Hydrophobic pseudo-endothelial implants for treating corneal edema
TWI464151B (zh) * 2009-07-06 2014-12-11 Alcon Inc 用於眼用鏡片材料之uv/可見光吸收劑
AU2010289896B2 (en) 2009-08-24 2013-08-29 Alcon Inc. Ophthalmic and otorhinolaryngological device materials
US8362177B1 (en) 2010-05-05 2013-01-29 Novartis Ag High refractive index ophthalmic device materials with reduced tack
TWI473823B (zh) * 2010-06-21 2015-02-21 Novartis Ag 具有經降低的閃光之高折射率、丙烯酸系眼科裝置材料
EP2591025B1 (de) 2010-07-05 2016-10-05 Dave, Jagrat Natavar Polymere zusammensetzung für okulare vorrichtungen
TWI517861B (zh) * 2011-02-08 2016-01-21 諾華公司 低黏度疏水性眼科裝置材料
TWI513768B (zh) * 2011-06-01 2015-12-21 Novartis Ag 疏水性丙烯酸系眼內水晶體材料
TWI551646B (zh) * 2011-06-03 2016-10-01 諾華公司 疏水性丙烯酸系眼內水晶體材料
EP3527348B1 (de) 2011-08-04 2021-11-10 Husky Injection Molding Systems Limited Werkzeug mit einer rückstandsreinigungsfunktion
EP2864285B1 (de) 2012-06-21 2016-10-19 Council of Scientific & Industrial Research (meth)acrylate mit hohem brechungsindex
JP6023340B2 (ja) * 2012-10-15 2016-11-09 ノバルティス アーゲー 粘着性の低い高屈折率眼用デバイス材料
US20150353667A1 (en) 2013-01-07 2015-12-10 Council Of Scientific & Industrial Research Flexible, high refractive index hydrophobic copolymer
WO2015038577A1 (en) 2013-09-10 2015-03-19 Colorado State University Research Foundation Synthetic polymeric materials and devices thereof
CN103483507A (zh) * 2013-10-14 2014-01-01 海昌隐形眼镜有限公司 一种软性亲水接触镜材料及其制备方法
EP3077429B1 (de) 2013-12-04 2018-09-26 Novartis AG Weiche hydrophobe acrylmaterial
CN105792860B (zh) 2013-12-04 2019-06-04 诺华股份有限公司 具有高折光指数和最小化的反光的软质丙烯酸材料
ES2750562T3 (es) 2014-12-16 2020-03-26 Alcon Inc Copolímeros hidrofóbicos de acrilato-acrilamida para dispositivos oftálmicos
EP3200840B1 (de) 2014-12-16 2021-11-17 Alcon Inc. Acrylat-acrylamid-copolymere mit geringem wassergehalt für ophthalmische vorrichtungen
JP6397136B2 (ja) 2015-02-16 2018-09-26 ノバルティス アーゲー 高屈折率を有するウエットパック眼内レンズ材料
WO2017015614A1 (en) * 2015-07-23 2017-01-26 The University Of North Carolina At Chapel Hill Solvent-free supersoft and superelastic materials
JP6262286B2 (ja) * 2016-05-27 2018-01-17 大日精化工業株式会社 高屈折率ポリマー及びその製造方法
JP7087004B2 (ja) 2017-06-05 2022-06-20 アルコン インコーポレイティド 高屈折率、高アッベ数の眼内レンズ材料
RU2726130C1 (ru) * 2019-11-05 2020-07-09 Общество с ограниченной ответственностью "Терагерцовая и инфракрасная фотоника" (ООО "ТИНФОТОНИКА") Способ оценки гидратации роговицы глаза в субтерагерцевом диапазоне частот
CN112279959B (zh) * 2020-10-26 2022-05-03 康小林 眼科聚合物材料、制备方法及其用途
CN121218954A (zh) * 2023-06-02 2025-12-26 Rx视觉股份有限公司 具有先进聚合控制的光可调人工晶状体
JP7609389B1 (ja) * 2023-10-25 2025-01-07 Fuloジャパン株式会社 眼内レンズ材料及び眼内レンズ

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3842059A (en) 1971-02-22 1974-10-15 M Chiang Acrylate and methacrylate terminated polystyrene macromolecular monomers having a substantially uniform molecular weight distribution
US3862077A (en) 1971-02-22 1975-01-21 Cpc International Inc Stable latexes of a chemically joined, phase separated thermoplastic graft copolymer and method for preparing the same
US4528311A (en) * 1983-07-11 1985-07-09 Iolab Corporation Ultraviolet absorbing polymers comprising 2-hydroxy-5-acrylyloxyphenyl-2H-benzotriazoles
US4834750A (en) 1987-09-17 1989-05-30 Ioptex Research, Inc. Deformable-elastic intraocular lens
US5290892A (en) 1990-11-07 1994-03-01 Nestle S.A. Flexible intraocular lenses made from high refractive index polymers
US5331073A (en) 1992-11-09 1994-07-19 Allergan, Inc. Polymeric compositions and intraocular lenses made from same
US5603774A (en) 1993-09-27 1997-02-18 Alcon Laboratories, Inc. Method for reducing tackiness of soft acrylic polymers
US5470932A (en) 1993-10-18 1995-11-28 Alcon Laboratories, Inc. Polymerizable yellow dyes and their use in opthalmic lenses
JP3377266B2 (ja) * 1993-12-10 2003-02-17 株式会社メニコン 軟質眼用レンズ材料
KR100331456B1 (ko) 1995-06-07 2002-10-25 알콘 래보레이토리스, 인코퍼레이티드 개선된고굴절율안과용렌즈물질
US6822016B2 (en) * 2001-09-10 2004-11-23 Johnson & Johnson Vision Care, Inc. Biomedical devices containing internal wetting agents
SE9800853D0 (sv) 1998-03-16 1998-03-16 Pharmacia & Upjohn Bv Intraocular lens
US6245106B1 (en) 1998-10-29 2001-06-12 Allergan Sales, Inc. Intraocular lenses made from polymeric compositions and monomers useful in said compositions
US6241766B1 (en) 1998-10-29 2001-06-05 Allergan Sales, Inc. Intraocular lenses made from polymeric compositions
USRE38935E1 (en) 1998-10-29 2006-01-10 Advanced Medical Optics, Inc. Intraocular lenses made from polymeric compositions and monomers useful in said compositions
US6450642B1 (en) * 1999-01-12 2002-09-17 California Institute Of Technology Lenses capable of post-fabrication power modification
EP1210380B1 (de) * 1999-09-07 2005-03-16 Alcon Inc. Material für faltbare ophtalmische und otorhinolaryngologische gegenstände
CA2381177A1 (en) 1999-09-07 2001-03-15 Charles Freeman Ophthalmic and otorhinolaryngological device materials
US6703466B1 (en) * 2001-06-18 2004-03-09 Alcon, Inc. Foldable intraocular lens optics having a glassy surface
US6730767B2 (en) 2001-11-02 2004-05-04 Bausch & Lomb Incorporated High refractive index aromatic-based siloxane monofunctional macromonomers
US6762271B2 (en) 2001-11-02 2004-07-13 Bausch & Lomb Incorporated High refractive index aromatic-based silyl monomers
US6723816B2 (en) 2001-11-02 2004-04-20 Bausch & Lomb Incorporated High refractive index aromatic-based siloxane difunctional macromonomers
ES2301830T3 (es) 2002-07-16 2008-07-01 Alcon, Inc. Materiales para dispositivos oftalmicos y otorrinolaringologicos.
US6983814B2 (en) 2003-07-11 2006-01-10 Harley-Davidson Motor Company Group, Inc. Oil tank cap
US6872793B1 (en) 2003-08-07 2005-03-29 Alcon, Inc. Ophthalmic and otorhinolaryngological device materials
JP4566536B2 (ja) * 2003-09-18 2010-10-20 株式会社メニコン 眼用レンズ材料
GB0410582D0 (en) 2004-05-12 2004-06-16 Vista Optics Ltd Compositions for use in the manufacture of lenses
RU2269552C1 (ru) * 2004-12-23 2006-02-10 Институт Катализа Им. Г.К. Борескова Сибирского Отделения Российской Академии Наук Полимерная композиция для мягких контактных линз продленного ношения и способ ее получения
KR101308951B1 (ko) 2005-06-13 2013-09-24 알콘, 인코퍼레이티드 안과적 및 이비인후과적 장치용 물질
CN101193929B (zh) 2005-06-13 2012-02-01 爱尔康公司 眼科和耳鼻喉科装置材料
US20070197681A1 (en) 2006-02-22 2007-08-23 Advanced Medical Optics Lens surface enhancement

Also Published As

Publication number Publication date
EP2043699A2 (de) 2009-04-08
AU2007275227A1 (en) 2008-01-24
ES2371576T3 (es) 2012-01-05
JP2009544364A (ja) 2009-12-17
TW200812654A (en) 2008-03-16
AU2007275227B2 (en) 2012-03-15
US7585900B2 (en) 2009-09-08
RU2009106049A (ru) 2010-08-27
IL196467A (en) 2012-10-31
JP5177823B2 (ja) 2013-04-10
AR062015A1 (es) 2008-08-10
KR20090064530A (ko) 2009-06-19
CA2657633C (en) 2014-05-06
BRPI0715431A2 (pt) 2013-07-23
CN101563115B (zh) 2013-06-19
RU2433837C2 (ru) 2011-11-20
NZ574812A (en) 2010-09-30
ZA200900319B (en) 2010-03-31
KR101403316B1 (ko) 2014-06-16
BRPI0715431B1 (pt) 2018-07-03
US20080021129A1 (en) 2008-01-24
NO20090793L (no) 2009-04-20
CA2657633A1 (en) 2008-01-24
WO2008011566A3 (en) 2009-04-09
TWI399228B (zh) 2013-06-21
CN101563115A (zh) 2009-10-21
BRPI0715431B8 (pt) 2021-06-22
MX2009000821A (es) 2009-02-03
IL196467A0 (en) 2009-11-18
WO2008011566A2 (en) 2008-01-24
EP2043699B1 (de) 2011-09-28

Similar Documents

Publication Publication Date Title
ATE507853T1 (de) Materialien für ophthalmische und otorhinolaryngologische geräte
ATE510568T1 (de) Materialien für ophthalmische und otorhinolaryngologische geräte
ATE507852T1 (de) Materialien für ophthalmische und otorhinolaryngologische geräte
EP2265234A4 (de) Medizinische verbände mit ventil und diese enthaltende kits
IL196467A0 (en) Low-tack ophthalmic and otorhinolaryngological device materials
DE602008006745D1 (de) Materialien für ophthalmische und otorhinolaryngologische geräte mit einem alkylphenolethoxylat
ATE505217T1 (de) Materialien für ophthalmische und otorhinolaryngologische geräte mit einem alkylethoxylat
CR10769A (es) Improvements in and relating to drive mechanisms suitable for use in drug delicery devices
IL196468A0 (en) Low-tack ophthalmic and otorhinolaryngological device materials
DE602008004639D1 (de) Materialien für ophthalmische und otorhinolaryngologische geräte mit phenylen-siloxan-makromeren
SM200600005006S2 (it) Orologi e vetri per orologi
SM200600005022S2 (it) Orologi e vetri per orologi
SM200600005010S2 (it) Orologi e vetri per orologi
SM200600005023S3 (it) Orologi e vetri per orologi
SM200600005007S2 (it) Orologi e vetri per orologi
SM200600005018S3 (it) Orologi e vetri per orologi
SM200600005025S2 (it) Orologi e vetri per orologi
SM200600005011S3 (it) Orologi e vetri per orologi
SM200600005014S2 (it) Orologi e vetri per orologi
SM200600005009S2 (it) Orologi e vetri per orologi
SM200600005003S3 (it) Orologi e vetri per orologi
SM200600005027S3 (it) Orologi e vetri per orologi
SM200600005024S2 (it) Orologi e vetri per orologi
SM200600005019S2 (it) Orologi e vetri per orologi
SM200600005020S2 (it) Orologi e vetri per orologi

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties