ATE526378T1 - Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen - Google Patents
Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungenInfo
- Publication number
- ATE526378T1 ATE526378T1 AT06813260T AT06813260T ATE526378T1 AT E526378 T1 ATE526378 T1 AT E526378T1 AT 06813260 T AT06813260 T AT 06813260T AT 06813260 T AT06813260 T AT 06813260T AT E526378 T1 ATE526378 T1 AT E526378T1
- Authority
- AT
- Austria
- Prior art keywords
- coatings
- silk fibroin
- methods
- layered
- deposition
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 108010022355 Fibroins Proteins 0.000 title abstract 3
- 230000008021 deposition Effects 0.000 title 1
- 238000000576 coating method Methods 0.000 abstract 3
- 239000000463 material Substances 0.000 abstract 2
- 102000004127 Cytokines Human genes 0.000 abstract 1
- 108090000695 Cytokines Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000012620 biological material Substances 0.000 abstract 1
- 238000012993 chemical processing Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 238000009501 film coating Methods 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 239000010409 thin film Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/08—Materials for coatings
- A61L31/10—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
- A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
- C09D189/00—Coating compositions based on proteins; Coating compositions based on derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/43—Hormones, e.g. dexamethasone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31725—Of polyamide
- Y10T428/31768—Natural source-type polyamide [e.g., casein, gelatin, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Botany (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Materials For Medical Uses (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70462205P | 2005-08-02 | 2005-08-02 | |
| US72883705P | 2005-10-21 | 2005-10-21 | |
| PCT/US2006/029826 WO2007016524A2 (en) | 2005-08-02 | 2006-07-28 | Methods for stepwise deposition of silk fibroin coatings |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE526378T1 true ATE526378T1 (de) | 2011-10-15 |
Family
ID=37603233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06813260T ATE526378T1 (de) | 2005-08-02 | 2006-07-28 | Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US8354501B2 (de) |
| EP (1) | EP1915436B1 (de) |
| AT (1) | ATE526378T1 (de) |
| CA (1) | CA2645934C (de) |
| ES (1) | ES2374428T3 (de) |
| WO (1) | WO2007016524A2 (de) |
Families Citing this family (112)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003249366A1 (en) * | 2002-06-24 | 2004-01-06 | Tufts University | Silk biomaterials and methods of use thereof |
| WO2004062697A2 (en) | 2003-01-07 | 2004-07-29 | Tufts University | Silk fibroin materials and use thereof |
| EP1613796B1 (de) | 2003-04-10 | 2017-03-22 | Tufts University | Konzentrierte wässrige seidenfibroinlösung und deren verwendung |
| WO2005000483A1 (en) * | 2003-06-06 | 2005-01-06 | Tufts University | Method for forming inorganic coatings |
| KR101260981B1 (ko) | 2004-06-04 | 2013-05-10 | 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 | 인쇄가능한 반도체소자들의 제조 및 조립방법과 장치 |
| ATE526378T1 (de) | 2005-08-02 | 2011-10-15 | Tufts College | Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen |
| CA2704768A1 (en) * | 2006-11-03 | 2008-10-23 | Trustees Of Tufts College | Biopolymer sensor and method of manufacturing the same |
| US9969134B2 (en) | 2006-11-03 | 2018-05-15 | Trustees Of Tufts College | Nanopatterned biopolymer optical device and method of manufacturing the same |
| WO2008127403A2 (en) | 2006-11-03 | 2008-10-23 | Trustees Of Tufts College | Biopolymer optofluidic device and method of manufacturing the same |
| WO2008108838A2 (en) * | 2006-11-21 | 2008-09-12 | Charles Stark Draper Laboratory, Inc. | Microfluidic devices and methods for fabricating the same |
| US9102916B2 (en) * | 2007-02-27 | 2015-08-11 | Trustees Of Tufts College | Tissue-engineered silk organs |
| US8187616B2 (en) | 2007-05-29 | 2012-05-29 | Trustees Of Tufts College | Method for silk fibroin gelation using sonication |
| WO2009023615A1 (en) * | 2007-08-10 | 2009-02-19 | Trustees Of Tufts College | Tubular silk compositions and methods of use thereof |
| CN101406713B (zh) * | 2007-10-12 | 2012-09-19 | 微创医疗器械(上海)有限公司 | 一种人工血管支架及其制备方法 |
| WO2009100280A2 (en) * | 2008-02-07 | 2009-08-13 | Trustees Of Tufts College | 3-dimensional silk hydroxyapatite compositions |
| US8206774B2 (en) * | 2008-03-13 | 2012-06-26 | Trustees Of Tufts College | Diazonium salt modification of silk polymer |
| WO2009126689A2 (en) * | 2008-04-08 | 2009-10-15 | Trustees Of Tufts College | System and method for making biomaterial structures |
| WO2009140588A1 (en) * | 2008-05-15 | 2009-11-19 | Trustees Of Tufts College | Silk polymer-based adenosine release: therapeutic potential for epilepsy |
| US8501172B2 (en) | 2008-09-26 | 2013-08-06 | Trustees Of Tufts College | pH-induced silk gels and uses thereof |
| US8372726B2 (en) | 2008-10-07 | 2013-02-12 | Mc10, Inc. | Methods and applications of non-planar imaging arrays |
| JP5646492B2 (ja) | 2008-10-07 | 2014-12-24 | エムシー10 インコーポレイテッドMc10,Inc. | 伸縮可能な集積回路およびセンサアレイを有する装置 |
| US8886334B2 (en) | 2008-10-07 | 2014-11-11 | Mc10, Inc. | Systems, methods, and devices using stretchable or flexible electronics for medical applications |
| US8097926B2 (en) | 2008-10-07 | 2012-01-17 | Mc10, Inc. | Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy |
| US8389862B2 (en) | 2008-10-07 | 2013-03-05 | Mc10, Inc. | Extremely stretchable electronics |
| JP5896743B2 (ja) * | 2008-10-09 | 2016-03-30 | タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ | グリセロールを含有する改変された絹フィルム |
| US9308070B2 (en) | 2008-12-15 | 2016-04-12 | Allergan, Inc. | Pliable silk medical device |
| EP2421549B1 (de) * | 2009-04-20 | 2013-06-12 | Allergan, Inc. | Seiden-fibroin-hydrogele und ihre verwendungen |
| US9861725B2 (en) | 2009-05-28 | 2018-01-09 | Addbio Ab | Multilayer protein films, methods of making, and drug delivery devices and biomedical implants employing the films |
| EP2453931A4 (de) | 2009-07-14 | 2014-04-30 | Tufts College | Wundheilungssysteme mit einem elektrogesponnenen seidenmaterial |
| US9440005B2 (en) * | 2009-08-21 | 2016-09-13 | National Institute Of Agrobiological Sciences | Substrate for feeding cells and/or tissues, cell/tissue-feeder and method for the production of the same, method for the regeneration of tissues, and method for the production of porous bodies |
| EP2483460B1 (de) | 2009-09-28 | 2015-09-02 | Trustees Of Tufts College | Verfahren zur herstellung gezogene seiden-egel-fasern |
| IN2012DN02358A (de) | 2009-09-29 | 2015-08-21 | Tufts College | |
| WO2011041727A1 (en) | 2009-10-01 | 2011-04-07 | Mc10, Inc. | Protective cases with integrated electronics |
| WO2011115643A1 (en) | 2010-03-17 | 2011-09-22 | The Board Of Trustees Of The University Of Illinois | Implantable biomedical devices on bioresorbable substrates |
| US9936574B2 (en) | 2009-12-16 | 2018-04-03 | The Board Of Trustees Of The University Of Illinois | Waterproof stretchable optoelectronics |
| US10441185B2 (en) | 2009-12-16 | 2019-10-15 | The Board Of Trustees Of The University Of Illinois | Flexible and stretchable electronic systems for epidermal electronics |
| EP2513953B1 (de) | 2009-12-16 | 2017-10-18 | The Board of Trustees of the University of Illionis | Elektrophysiologie unter verwendung konformer elektronischer vorrichtungen |
| WO2011109691A2 (en) | 2010-03-05 | 2011-09-09 | Trustees Of Tufts College | Silk-based ionomeric compositions |
| WO2011112931A1 (en) | 2010-03-12 | 2011-09-15 | The Board Of Trustees Of The University Of Illinois | Waterproof stretchable optoelectronics |
| CN103181025A (zh) | 2010-04-12 | 2013-06-26 | 塔夫茨大学 | 丝电子部件 |
| US9566365B2 (en) | 2010-09-01 | 2017-02-14 | Trustees Of Tufts College | Silk fibroin and polyethylene glycol-based biomaterials |
| WO2012031282A2 (en) | 2010-09-03 | 2012-03-08 | Tufts University/Trustees Of Tufts College | Plasmonic nanoparticle-doped silk materials |
| JP2014502416A (ja) | 2010-09-27 | 2014-01-30 | タフツ ユニバーシティー/トラスティーズ オブ タフツ カレッジ | 絹ベースの圧電性材料 |
| EP3495015B1 (de) | 2010-10-19 | 2022-12-07 | Trustees Of Tufts College | Mikronadeln auf seidenfibroinbasis und verfahren zur herstellung davon |
| EP2638507B1 (de) * | 2010-11-12 | 2016-01-27 | AbbVie Inc. | Optisches hochdurchsatzverfahren und system zur bestimmung der wirkung einer testsubstanz auf lebende zellen |
| WO2012145652A1 (en) * | 2011-04-20 | 2012-10-26 | Trustees Of Tufts College | Dynamic silk coatings for implantable devices |
| BR112013027057A2 (pt) * | 2011-04-21 | 2020-08-11 | Trustees Of Tufts College | composições e métodos para a estabilização de agentes ativos |
| US9765934B2 (en) | 2011-05-16 | 2017-09-19 | The Board Of Trustees Of The University Of Illinois | Thermally managed LED arrays assembled by printing |
| KR102000302B1 (ko) | 2011-05-27 | 2019-07-15 | 엠씨10, 인크 | 전자, 광학, 및/또는 기계 장치 및 시스템, 그리고 이를 제조하기 위한 방법 |
| US8934965B2 (en) | 2011-06-03 | 2015-01-13 | The Board Of Trustees Of The University Of Illinois | Conformable actively multiplexed high-density surface electrode array for brain interfacing |
| US20140370094A1 (en) | 2011-11-08 | 2014-12-18 | Tufts University | Silk-based scaffold platform for engineering tissue constructs |
| JP6362540B2 (ja) | 2011-11-09 | 2018-07-25 | トラスティーズ・オブ・タフツ・カレッジTrustees Of Tufts College | 注射可能なシルクフィブロイン粒子およびその使用 |
| AU2012335122B2 (en) | 2011-11-09 | 2016-09-22 | Trustees Of Tufts College | Injectable silk fibroin foams and uses thereof |
| WO2013089867A2 (en) | 2011-12-01 | 2013-06-20 | The Board Of Trustees Of The University Of Illinois | Transient devices designed to undergo programmable transformations |
| US10126467B2 (en) | 2011-12-05 | 2018-11-13 | Tufts University | Signal enhancement by silk photonic crystals |
| HK1201761A1 (en) | 2011-12-29 | 2015-09-11 | Trustees Of Tufts College | Functionalization of biomaterials to control regeneration and inflammation responses |
| EP3884931A3 (de) | 2012-02-06 | 2021-12-01 | Children's Medical Center, Corp. | Mehrschichtiges biomaterial zur geweberegenerierung und wundheilung |
| US9554484B2 (en) | 2012-03-30 | 2017-01-24 | The Board Of Trustees Of The University Of Illinois | Appendage mountable electronic devices conformable to surfaces |
| WO2013152265A1 (en) | 2012-04-06 | 2013-10-10 | Trustees Of Tufts College | Methods of producing and using silk microfibers |
| JP2015512944A (ja) | 2012-04-13 | 2015-04-30 | トラスティーズ・オブ・タフツ・カレッジTrustees Of Tufts College | 絹マイクロスフェアを調製するための方法および組成物 |
| HK1207977A1 (en) | 2012-04-25 | 2016-02-19 | Trustees Of Tufts College | Silk microspheres and methods for surface lubrication |
| US9171794B2 (en) | 2012-10-09 | 2015-10-27 | Mc10, Inc. | Embedding thin chips in polymer |
| CA2887495A1 (en) * | 2012-10-11 | 2014-04-17 | Tufts University | Silk reservoirs for sustained delivery of anti-cancer agents |
| WO2014066884A1 (en) | 2012-10-26 | 2014-05-01 | Tufts University | Silk-based fabrication techniques to prepare high strength calcium phosphate ceramic scaffolds |
| WO2014077881A1 (en) * | 2012-11-14 | 2014-05-22 | Hollister Incorporated | Urinary catheters having varying flexibility |
| EP2925822A4 (de) | 2012-11-27 | 2016-10-12 | Univ Tufts | Biopolymerbasierte tinten und verwendung davon |
| US20150368417A1 (en) * | 2013-02-15 | 2015-12-24 | Tufts University | Silk-based nanoimprinting |
| US10464361B2 (en) | 2013-03-15 | 2019-11-05 | Tufts University | Silk water lithography |
| US11376329B2 (en) | 2013-03-15 | 2022-07-05 | Trustees Of Tufts College | Low molecular weight silk compositions and stabilizing silk compositions |
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| US9731052B2 (en) | 2017-08-15 |
| US20090202614A1 (en) | 2009-08-13 |
| US20130156844A1 (en) | 2013-06-20 |
| EP1915436A2 (de) | 2008-04-30 |
| EP1915436B1 (de) | 2011-09-28 |
| CA2645934C (en) | 2014-04-29 |
| US8354501B2 (en) | 2013-01-15 |
| ES2374428T3 (es) | 2012-02-16 |
| WO2007016524A2 (en) | 2007-02-08 |
| US20150231311A1 (en) | 2015-08-20 |
| WO2007016524A3 (en) | 2007-04-05 |
| US20130287835A1 (en) | 2013-10-31 |
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