ATE526378T1 - Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen - Google Patents

Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen

Info

Publication number
ATE526378T1
ATE526378T1 AT06813260T AT06813260T ATE526378T1 AT E526378 T1 ATE526378 T1 AT E526378T1 AT 06813260 T AT06813260 T AT 06813260T AT 06813260 T AT06813260 T AT 06813260T AT E526378 T1 ATE526378 T1 AT E526378T1
Authority
AT
Austria
Prior art keywords
coatings
silk fibroin
methods
layered
deposition
Prior art date
Application number
AT06813260T
Other languages
English (en)
Inventor
David Kaplan
Xianyan Wang
Original Assignee
Tufts College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37603233&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE526378(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tufts College filed Critical Tufts College
Application granted granted Critical
Publication of ATE526378T1 publication Critical patent/ATE526378T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/32—Proteins, polypeptides; Degradation products or derivatives thereof, e.g. albumin, collagen, fibrin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D189/00—Coating compositions based on proteins; Coating compositions based on derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/43—Hormones, e.g. dexamethasone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/31504—Composite [nonstructural laminate]
    • Y10T428/31725—Of polyamide
    • Y10T428/31768—Natural source-type polyamide [e.g., casein, gelatin, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Paints Or Removers (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
AT06813260T 2005-08-02 2006-07-28 Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen ATE526378T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70462205P 2005-08-02 2005-08-02
US72883705P 2005-10-21 2005-10-21
PCT/US2006/029826 WO2007016524A2 (en) 2005-08-02 2006-07-28 Methods for stepwise deposition of silk fibroin coatings

Publications (1)

Publication Number Publication Date
ATE526378T1 true ATE526378T1 (de) 2011-10-15

Family

ID=37603233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06813260T ATE526378T1 (de) 2005-08-02 2006-07-28 Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen

Country Status (6)

Country Link
US (4) US8354501B2 (de)
EP (1) EP1915436B1 (de)
AT (1) ATE526378T1 (de)
CA (1) CA2645934C (de)
ES (1) ES2374428T3 (de)
WO (1) WO2007016524A2 (de)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004000915A2 (en) * 2002-06-24 2003-12-31 Tufts University Silk biomaterials and methods of use thereof
US7842780B2 (en) 2003-01-07 2010-11-30 Trustees Of Tufts College Silk fibroin materials and use thereof
EP3231846A1 (de) 2003-04-10 2017-10-18 Tufts University Konzentrierte wässrige seidenfibroinlösung und verwendung davon
WO2005000483A1 (en) * 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
EP2650907B1 (de) 2004-06-04 2024-10-23 The Board Of Trustees Of The University Of Illinois Verfahren und Einrichtungen zum Herstellen und Zusammenbauen von druckbaren Halbleiterelementen
ATE526378T1 (de) 2005-08-02 2011-10-15 Tufts College Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen
US9969134B2 (en) 2006-11-03 2018-05-15 Trustees Of Tufts College Nanopatterned biopolymer optical device and method of manufacturing the same
EP2101975A2 (de) * 2006-11-03 2009-09-23 Trustees of Tufts College Biopolymersensor und herstellungsverfahren dafür
US8574461B2 (en) 2006-11-03 2013-11-05 Tufts University Electroactive biopolymer optical and electro-optical devices and method of manufacturing the same
US8975073B2 (en) 2006-11-21 2015-03-10 The Charles Stark Draper Laboratory, Inc. Microfluidic device comprising silk films coupled to form a microchannel
JP2010522583A (ja) 2007-02-27 2010-07-08 トラスティーズ オブ タフツ カレッジ 組織工学的に作製された絹製臓器
EA019118B1 (ru) 2007-05-29 2014-01-30 Трастиз Оф Тафтс Колледж Способ желатинизации фиброина шелка и регулирования времени желатинизации, способ инкапсуляции по меньшей мере одного компонента в фиброин шелка (варианты)
US9808557B2 (en) 2007-08-10 2017-11-07 Trustees Of Tufts College Tubular silk compositions and methods of use thereof
CN101406713B (zh) * 2007-10-12 2012-09-19 微创医疗器械(上海)有限公司 一种人工血管支架及其制备方法
WO2009100280A2 (en) * 2008-02-07 2009-08-13 Trustees Of Tufts College 3-dimensional silk hydroxyapatite compositions
US8206774B2 (en) * 2008-03-13 2012-06-26 Trustees Of Tufts College Diazonium salt modification of silk polymer
US9068282B2 (en) * 2008-04-08 2015-06-30 Trustees Of Tufts College System and method for making biomaterial structures
WO2009140588A1 (en) * 2008-05-15 2009-11-19 Trustees Of Tufts College Silk polymer-based adenosine release: therapeutic potential for epilepsy
US8501172B2 (en) * 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
US8389862B2 (en) 2008-10-07 2013-03-05 Mc10, Inc. Extremely stretchable electronics
US8097926B2 (en) 2008-10-07 2012-01-17 Mc10, Inc. Systems, methods, and devices having stretchable integrated circuitry for sensing and delivering therapy
US8886334B2 (en) 2008-10-07 2014-11-11 Mc10, Inc. Systems, methods, and devices using stretchable or flexible electronics for medical applications
US8372726B2 (en) 2008-10-07 2013-02-12 Mc10, Inc. Methods and applications of non-planar imaging arrays
US9289132B2 (en) 2008-10-07 2016-03-22 Mc10, Inc. Catheter balloon having stretchable integrated circuitry and sensor array
MX2011003618A (es) 2008-10-09 2011-06-16 Tufts College Peliculas de seda modificadas que contienen glicerol.
US9308070B2 (en) 2008-12-15 2016-04-12 Allergan, Inc. Pliable silk medical device
ES2443045T5 (es) * 2009-04-20 2021-05-10 Allergan Inc Hidrogeles de fibroína de seda y usos de éstos
PL2435102T3 (pl) 2009-05-28 2021-01-11 Addbio Ab Wielowarstwowe folie białkowe, sposoby ich wytwarzania, urządzenia do podawania leku oraz implanty biomedyczne wykorzystujące folie
WO2011008842A2 (en) 2009-07-14 2011-01-20 Trustees Of Tufts College Electrospun silk material systems for wound healing
JP5789799B2 (ja) * 2009-08-21 2015-10-07 国立研究開発法人農業生物資源研究所 多孔質体の製造方法、細胞又は組織供給用支持体の製造方法、及び組織供給体の製造方法
JP2013506058A (ja) 2009-09-28 2013-02-21 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ 延伸したシルクｅｇｅｌ繊維およびその製造方法
IN2012DN02358A (de) 2009-09-29 2015-08-21 Tufts College
WO2011041727A1 (en) 2009-10-01 2011-04-07 Mc10, Inc. Protective cases with integrated electronics
US10441185B2 (en) 2009-12-16 2019-10-15 The Board Of Trustees Of The University Of Illinois Flexible and stretchable electronic systems for epidermal electronics
US9936574B2 (en) 2009-12-16 2018-04-03 The Board Of Trustees Of The University Of Illinois Waterproof stretchable optoelectronics
EP2513953B1 (de) 2009-12-16 2017-10-18 The Board of Trustees of the University of Illionis Elektrophysiologie unter verwendung konformer elektronischer vorrichtungen
US9603971B2 (en) 2010-03-05 2017-03-28 Trustees Of Tufts College Silk-based ionomeric compositions
TWI646988B (zh) 2010-03-12 2019-01-11 美國伊利諾大學理事會 生物醫學裝置及其製造方法、流體遞送監視器、監視在管子中流動之流體的方法、近接感測器及感測兩個物件之間的距離的方法
CN104224171B (zh) 2010-03-17 2017-06-09 伊利诺伊大学评议会 基于生物可吸收基质的可植入生物医学装置
JP2013533754A (ja) 2010-04-12 2013-08-29 タフツ・ユニバーシティ 絹電子部品
JP6081358B2 (ja) 2010-09-01 2017-02-15 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 絹フィブロインおよびポリエチレングリコールをベースとする生体材料
CA2847590A1 (en) 2010-09-03 2012-03-08 Tufts University/Trustees Of Tufts College Plasmonic nanoparticle-doped silk materials
WO2012047682A2 (en) * 2010-09-27 2012-04-12 Tufts University Trustees Of Tufts College Silk-based piezoelectric materials
EP4218891A1 (de) 2010-10-19 2023-08-02 Trustees Of Tufts College Mikronadeln auf seidenfibroinbasis und verfahren zur herstellung davon
ES2564855T3 (es) * 2010-11-12 2016-03-29 Abbvie Inc. Método y sistema óptico de alto rendimiento para determinar el efecto de una sustancia de ensayo sobre las células vivas
US10335519B2 (en) 2011-04-20 2019-07-02 Trustees Of Tufts College Dynamic silk coatings for implantable devices
JP6170906B2 (ja) * 2011-04-21 2017-07-26 トラスティーズ・オブ・タフツ・カレッジＴｒｕｓｔｅｅｓ Ｏｆ Ｔｕｆｔｓ Ｃｏｌｌｅｇｅ 活性物質を安定化させるための組成物および方法
WO2012158709A1 (en) 2011-05-16 2012-11-22 The Board Of Trustees Of The University Of Illinois Thermally managed led arrays assembled by printing
WO2012166686A2 (en) 2011-05-27 2012-12-06 Mc10, Inc. Electronic, optical and/or mechanical apparatus and systems and methods for fabricating same
US8934965B2 (en) 2011-06-03 2015-01-13 The Board Of Trustees Of The University Of Illinois Conformable actively multiplexed high-density surface electrode array for brain interfacing
US20140370094A1 (en) 2011-11-08 2014-12-18 Tufts University Silk-based scaffold platform for engineering tissue constructs
MX2014005704A (es) 2011-11-09 2015-02-17 Tufts College Espumas de fibroina de seda inyectables y sus usos.
MX2014005702A (es) 2011-11-09 2015-02-17 Tufts College Particulas de fibroina de seda inyectables y sus usos.
US9691873B2 (en) 2011-12-01 2017-06-27 The Board Of Trustees Of The University Of Illinois Transient devices designed to undergo programmable transformations
US10126467B2 (en) 2011-12-05 2018-11-13 Tufts University Signal enhancement by silk photonic crystals
EP2797641B1 (de) 2011-12-29 2019-07-10 Trustees Of Tufts College Funktionalisierung von biomaterialien zur steuerung von regenerations- und entzündungsreaktionen
ES2856873T3 (es) 2012-02-06 2021-09-28 Childrens Medical Center Biomaterial multicapa para la regeneración de tejidos y la cicatrización de las heridas
JP2015521303A (ja) 2012-03-30 2015-07-27 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシ 表面への形状適合可能な付属物装着可能電子デバイス
WO2013152265A1 (en) 2012-04-06 2013-10-10 Trustees Of Tufts College Methods of producing and using silk microfibers
WO2013155404A1 (en) 2012-04-13 2013-10-17 Trustees Of Tufts College Methods and compositions for preparing a silk microsphere
WO2013163407A1 (en) 2012-04-25 2013-10-31 Trustees Of Tufts College Silk microspheres and methods for surface lubrication
US9171794B2 (en) 2012-10-09 2015-10-27 Mc10, Inc. Embedding thin chips in polymer
US20150238617A1 (en) * 2012-10-11 2015-08-27 Tufts University Silk reservoirs for sustained delivery of anti-cancer agents
WO2014066884A1 (en) 2012-10-26 2014-05-01 Tufts University Silk-based fabrication techniques to prepare high strength calcium phosphate ceramic scaffolds
EP2919844B1 (de) * 2012-11-14 2022-08-10 Hollister Incorporated Harnkatheter mit variabler flexibilität
WO2014085725A1 (en) 2012-11-27 2014-06-05 Tufts University Biopolymer-based inks and use thereof
US20150368417A1 (en) * 2013-02-15 2015-12-24 Tufts University Silk-based nanoimprinting
US11009792B2 (en) 2013-03-15 2021-05-18 Tufts University All water-based nanopatterning
WO2014144971A1 (en) 2013-03-15 2014-09-18 Tufts University Silk water lithography
US11376329B2 (en) 2013-03-15 2022-07-05 Trustees Of Tufts College Low molecular weight silk compositions and stabilizing silk compositions
WO2014169170A1 (en) 2013-04-12 2014-10-16 The Board Of Trustees Of The University Of Illinois Inorganic and organic transient electronic devices
US10292263B2 (en) 2013-04-12 2019-05-14 The Board Of Trustees Of The University Of Illinois Biodegradable materials for multilayer transient printed circuit boards
EP3000125A4 (de) 2013-05-22 2017-02-08 Transient Electronics, Inc. Kontrollierte umwandlung von nicht-transienter elektronik
US20160089854A1 (en) * 2013-05-24 2016-03-31 Tufts University Interface control of semi-crystalline biopolymer films
EP3036098A1 (de) * 2013-08-22 2016-06-29 Allergan, Inc. Implantierbare medizinische vorrichtungen
WO2015048527A1 (en) 2013-09-27 2015-04-02 Tufts University Optically transparent silk hydrogels
WO2015054125A1 (en) 2013-10-08 2015-04-16 Trustees Of Tufts College Tunable covalently crosslinked hydrogels and methods of making the same
WO2015070108A1 (en) 2013-11-08 2015-05-14 Tufts University Peptide-based nanofibrillar materials
WO2016086107A1 (en) * 2014-11-25 2016-06-02 Diagnostic Biochips, Inc. Coated biosensor and method for preserving biosensor during implantation into the brain or other tissues
PE20171791A1 (es) 2014-12-02 2017-12-28 Silk Therapeutics Inc Prendas de vestir de seda y productos de alto rendimiento y metodos para elaborarla
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
KR102625116B1 (ko) 2015-03-12 2024-01-12 터프츠 유니버시티 형상 메모리 실크 재료
EP3304130B1 (de) 2015-06-01 2021-10-06 The Board of Trustees of the University of Illinois Alternativer ansatz zur uv-erfassung
US10677647B2 (en) 2015-06-01 2020-06-09 The Board Of Trustees Of The University Of Illinois Miniaturized electronic systems with wireless power and near-field communication capabilities
HK1255640A1 (zh) 2015-07-14 2019-08-23 Evolved By Nature, Inc. 丝性能服装和产品及其制备方法
US20200054792A1 (en) 2015-07-28 2020-02-20 Trustees Of Tufts College Polypeptide monoliths
US10925543B2 (en) 2015-11-11 2021-02-23 The Board Of Trustees Of The University Of Illinois Bioresorbable silicon electronics for transient implants
US11833272B2 (en) 2015-12-17 2023-12-05 Trustees Of Tufts College Silk-fibroin hydrogels, methods of forming, and uses thereof
KR20190028381A (ko) * 2016-05-16 2019-03-18 스파이버 테크놀러지스 에이비 고체 표면의 거미 실크 코팅
WO2018006037A1 (en) 2016-07-01 2018-01-04 Trustees Of Tufts College Innervated artificial skin
WO2018013612A1 (en) * 2016-07-11 2018-01-18 Trustees Of Tufts College Artificial brain tissue
WO2018026853A1 (en) 2016-08-01 2018-02-08 Trustees Of Tufts College Biomimetic mechanical tension driven fabrication of nanofibrillar architecture
WO2018081815A2 (en) 2016-10-31 2018-05-03 Sofregen Medical, Inc. Compositions comprising silk fibroin particles and uses thereof
US11439728B2 (en) * 2017-03-23 2022-09-13 Council Of Scientific & Industrial Research Process for coating a biomedical implant with a biocompatible polymer and a biomedical implant therefrom
AU2018340499B2 (en) * 2017-09-26 2023-09-07 Spiber Technologies Ab Structuring of surface-active macromolecules
US11390988B2 (en) 2017-09-27 2022-07-19 Evolved By Nature, Inc. Silk coated fabrics and products and methods of preparing the same
US20210085598A1 (en) 2018-04-03 2021-03-25 Vaxess Technologies, Inc. Microneedle comprising silk fibroin applied to a dissolvable base
CN113412061A (zh) * 2018-12-10 2021-09-17 剑桥谷物公司 用于基于聚合物的保质期延长的组合物和方法
TWI691531B (zh) * 2019-02-11 2020-04-21 南臺學校財團法人南臺科技大學 蠶絲蛋白膜的製造方法
US11369473B2 (en) 2019-04-08 2022-06-28 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
US11779683B2 (en) 2019-04-08 2023-10-10 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
WO2020247594A1 (en) 2019-06-04 2020-12-10 Cocoon Biotech Inc. Silk-based products, formulations, and methods of use
US12611489B2 (en) 2019-09-06 2026-04-28 Rensselaer Polytechnic Institute Methods for generating surface coatings via self-assembly of silk fibroin and silk fibroin-like macromolecules
EP4045124A4 (de) 2019-10-15 2024-01-24 Sofregen Medical, Inc. Abgabevorrichtungen für die abgabe und verfahren zur abgabe von zusammensetzungen
CN112043877B (zh) * 2020-08-06 2022-10-14 苏州大学 一种蚕丝抗凝血管支架覆膜及其制备方法
US11976196B2 (en) 2021-04-14 2024-05-07 Cambridge Crops, Inc. Silk packaging applications
WO2022246342A1 (en) 2021-05-21 2022-11-24 Cambridge Crops, Inc. d/b/a Mori Systems and methods for manufacturing a silk fibroin solution and powders containing silk fibroin
US11864569B2 (en) 2021-08-16 2024-01-09 Cambridge Crops, Inc. Systems and methods for improving the performance of cereal using a silk fibroin solution and powders containing silk fibroin
CA3260638A1 (en) 2022-06-24 2023-12-28 Terrestrial Bio, Inc. MEDICATION TAMP APPLICATOR
EP4731294A1 (de) 2023-06-23 2026-04-29 Vaxess Technologies, Inc. Applikator für ein medikamentenpflaster
CN117445491B (zh) * 2023-12-06 2026-05-12 江西丝科生物科技有限公司 一种蛋白膜的复合方法及复合蛋白膜
CN120737363B (zh) * 2025-09-05 2025-11-21 苏州贝彩纳米科技有限公司 一种丝素蛋白基压电材料及其制备方法与应用

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2685570A (en) 1952-02-28 1954-08-03 Verdiers Edward Erlick Process for precipitating synthetic polyamides in combination with silk fiber
US3424164A (en) 1966-05-20 1969-01-28 Ethicon Inc Silk suture
EP0878513B1 (de) * 1993-05-24 2003-11-05 Idemitsu Petrochemical Co. Ltd. Feines Pulver aus natürlicher, organischer Substanz enthaltendes Überzugsmittel
WO1999025811A1 (en) * 1997-11-18 1999-05-27 Japan As Represented By Director General Of National Institute Of Sericultural And Entomological Science Ministry Of Agriculture, Forestry And Fisheries Epidermal cell growth activating material
JPH11243948A (ja) 1998-03-02 1999-09-14 Natl Inst Of Sericultural & Entomological Science 動物細胞増殖用の細胞培養床基材及びその調製方法
GB9806530D0 (en) * 1998-03-26 1998-05-27 Glaxo Group Ltd Inflammatory mediator
US7662409B2 (en) * 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US20030007991A1 (en) * 1998-09-25 2003-01-09 Masters David B. Devices including protein matrix materials and methods of making and using thereof
US20050090641A1 (en) * 2001-10-02 2005-04-28 Regina Valluzzi Self-assembling polymers, and materials fabricated therefrom
US6902932B2 (en) * 2001-11-16 2005-06-07 Tissue Regeneration, Inc. Helically organized silk fibroin fiber bundles for matrices in tissue engineering
JP3803962B2 (ja) 2001-12-28 2006-08-02 独立行政法人科学技術振興機構 絹タンパク質フィルムとその製造方法
JP3772207B2 (ja) * 2002-06-19 2006-05-10 独立行政法人農業生物資源研究所 生分解性生体高分子材料、その製造方法、およびこの高分子材料からなる機能性素材
WO2004000915A2 (en) 2002-06-24 2003-12-31 Tufts University Silk biomaterials and methods of use thereof
EP3231846A1 (de) 2003-04-10 2017-10-18 Tufts University Konzentrierte wässrige seidenfibroinlösung und verwendung davon
AU2004289362A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Intravascular devices and fibrosis-inducing agents
WO2005065079A2 (en) * 2003-11-10 2005-07-21 Angiotech International Ag Medical implants and fibrosis-inducing agents
CA2608862C (en) * 2004-06-11 2020-05-05 Trustees Of Tufts College Silk-based drug delivery system
US20080161251A1 (en) * 2005-01-21 2008-07-03 Astex Therapeutics Limited Pharmaceutical Compounds
US20090088679A1 (en) * 2005-02-07 2009-04-02 Massachusetts Institute Of Technology Electronically-Degradable Layer-by-Layer Thin Films
CN100368026C (zh) 2005-07-01 2008-02-13 复旦大学附属华山医院 一种丝素蛋白涂层钛网及其制备方法和应用
ATE526378T1 (de) 2005-08-02 2011-10-15 Tufts College Verfahren zur stufenweisen ablagerung von seidenfibroinbeschichtungen
US20100150991A1 (en) 2008-12-15 2010-06-17 Bernstein Brent H Combination Wound Therapy
US9732321B2 (en) * 2010-02-16 2017-08-15 The General Hospital Corporation Engineered craniofacial constructs with composite scaffold
JP2013533754A (ja) 2010-04-12 2013-08-29 タフツ・ユニバーシティ 絹電子部品
WO2013152265A1 (en) 2012-04-06 2013-10-10 Trustees Of Tufts College Methods of producing and using silk microfibers

Also Published As

Publication number Publication date
US20130287835A1 (en) 2013-10-31
US20130156844A1 (en) 2013-06-20
ES2374428T3 (es) 2012-02-16
WO2007016524A3 (en) 2007-04-05
WO2007016524A2 (en) 2007-02-08
US9731052B2 (en) 2017-08-15
EP1915436B1 (de) 2011-09-28
EP1915436A2 (de) 2008-04-30
CA2645934A1 (en) 2007-02-08
US20090202614A1 (en) 2009-08-13
CA2645934C (en) 2014-04-29
US8354501B2 (en) 2013-01-15
US20150231311A1 (en) 2015-08-20

Similar Documents

Publication Publication Date Title
WO2007016524A3 (en) Methods for stepwise deposition of silk fibroin coatings
Guo et al. Controlling cell adhesion using layer-by-layer approaches for biomedical applications
Chen et al. Preparation of super-hydrophobic surface on stainless steel
Tserepi et al. Plasma nanotextured polymeric surfaces for controlling cell attachment and proliferation: a short review
Neirinck et al. A current opinion on electrophoretic deposition in pulsed and alternating fields
Sardella et al. Non-equilibrium plasma processing for the preparation of antibacterial surfaces
DE602007008355D1 (de) Verfahren zur Herstellung von mikrofluidischen Vorrichtungen
FR2893266B1 (fr) Produit superhydrophile ou superhydrophobe, procede pour sa realisation et utilisation de ce produit
WO2011156596A3 (en) Articles having non-fouling surfaces and processes for preparing the same including pretreatment of substrates
BR112021020724A2 (pt) Artigo compreendendo um substrato revestido e método para revestir um substrato
AU2017271673A1 (en) Covalently modified surfaces, kits, and methods of preparation and use
WO2009076572A3 (en) Methods of making an article and articles
BR102013032886B8 (pt) composição de duas partes curável por umidade, método para revestir um substrato, e, artigo revestido
EA200801383A1 (ru) Получение наноразмерных материалов
WO2007064597A3 (en) Uniform surfaces for hybrid material substrates and methods for making and using same
Meng et al. Recent progress in biointerfaces with controlled bacterial adhesion by using chemical and physical methods
Islam et al. Nanotextured polymer substrates show enhanced cancer cell isolation and cell culture
WO2015042393A3 (en) Evolved sortases and uses thereof
MX2009010357A (es) Materiales para remover contaminantes de fluidos utilizando soportes con grupos derivados funcionalizados biologicamente y los metodos de formacion y uso de los mismos.
WO2007053326A3 (en) Compositions containing a silanol functional polymer and hydrophilic coating films
Wang et al. Electrostatic adsorption behavior of zwitterionic copolymers on negatively charged surfaces
ATE494322T1 (de) Hydrophiler überzug und herstellungsverfahren dafür
BR112017025317A2 (pt) processo para metalizar uma superfície
Calovi et al. Durability of acrylic cataphoretic coatings additivated with colloidal silver
Kim et al. Long‐term stable hydrophilic surface modification of poly (ether ether ketone) via the multilayered chemical grafting method

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties