ATE526403T1 - L-threonin-überproduktions-mikroorganismus und verfahren zur herstellung von l-threonin damit - Google Patents

L-threonin-überproduktions-mikroorganismus und verfahren zur herstellung von l-threonin damit

Info

Publication number
ATE526403T1
ATE526403T1 AT07768570T AT07768570T ATE526403T1 AT E526403 T1 ATE526403 T1 AT E526403T1 AT 07768570 T AT07768570 T AT 07768570T AT 07768570 T AT07768570 T AT 07768570T AT E526403 T1 ATE526403 T1 AT E526403T1
Authority
AT
Austria
Prior art keywords
threonine
producing
microorganism
overproduction
therefrom
Prior art date
Application number
AT07768570T
Other languages
English (en)
Inventor
Sang Yup Lee
Kwang Ho Lee
Jin Hwan Park
Tae Yong Kim
Original Assignee
Korea Advanced Inst Sci & Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Advanced Inst Sci & Tech filed Critical Korea Advanced Inst Sci & Tech
Application granted granted Critical
Publication of ATE526403T1 publication Critical patent/ATE526403T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT07768570T 2007-03-09 2007-07-02 L-threonin-überproduktions-mikroorganismus und verfahren zur herstellung von l-threonin damit ATE526403T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20070023370 2007-03-09
KR1020070039971A KR100858913B1 (ko) 2007-03-09 2007-04-24 부위특이적 변이에 의해 제조된 고수율의 ｌ－쓰레오닌생산균주 및 이를 이용한 ｌ－쓰레오닌의 제조방법
PCT/KR2007/003200 WO2008111708A1 (en) 2007-03-09 2007-07-02 L-threonine overproducing microorganism and method for preparing l-threonine using the same

Publications (1)

Publication Number Publication Date
ATE526403T1 true ATE526403T1 (de) 2011-10-15

Family

ID=40022014

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07768570T ATE526403T1 (de) 2007-03-09 2007-07-02 L-threonin-überproduktions-mikroorganismus und verfahren zur herstellung von l-threonin damit

Country Status (6)

Country Link
US (1) US8852898B2 (de)
EP (1) EP2121918B1 (de)
JP (1) JP4846021B2 (de)
KR (1) KR100858913B1 (de)
AT (1) ATE526403T1 (de)
WO (1) WO2008111708A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112012016908B1 (pt) * 2009-12-30 2020-03-31 Evonik Degussa Gmbh Linhagens e métodos para a produção de metionina
CN105821014A (zh) * 2015-01-07 2016-08-03 中国科学院天津工业生物技术研究所 嗜热共生杆菌meso-二氨基庚二酸脱氢酶突变体
KR101804017B1 (ko) * 2015-10-23 2017-12-04 씨제이제일제당 (주) Ｌ-쓰레오닌을 생산하는 재조합 미생물 및 이를 이용하여 ｌ-쓰레오닌을 생산하는 방법
US11535830B2 (en) 2017-07-11 2022-12-27 Adisseo France S.A.S. Threonine-producing yeast
KR102183209B1 (ko) * 2019-09-09 2020-11-26 씨제이제일제당 주식회사 L-쓰레오닌 배출 단백질의 변이체 및 이를 이용한 l-쓰레오닌 생산 방법
WO2021048353A1 (en) * 2019-09-11 2021-03-18 Evonik Operations Gmbh Coryneform bacteria with a heterologous threonine transporter and their use in the production of l-threonine
KR102126951B1 (ko) * 2019-09-26 2020-06-26 씨제이제일제당 주식회사 디하이드로디피콜린산 리덕타제 변이형 폴리펩티드 및 이를 이용한 l-쓰레오닌 생산방법
CN110590920B (zh) * 2019-09-30 2020-12-29 江南大学 一种l-丝氨酸转运蛋白及其应用
KR102527895B1 (ko) * 2021-01-11 2023-04-28 씨제이제일제당 (주) GlxR 단백질 변이체 또는 이를 이용한 쓰레오닌 생산방법
WO2022191358A1 (ko) * 2021-03-09 2022-09-15 대상 주식회사 L-라이신 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-라이신의 생산 방법
CN115404224B (zh) * 2021-05-27 2024-09-03 廊坊梅花生物技术开发有限公司 产l-苏氨酸基因工程菌及其构建方法与应用
CN116555251A (zh) * 2022-01-28 2023-08-08 廊坊梅花生物技术开发有限公司 一种生产苏氨酸的重组微生物及其应用
KR102801642B1 (ko) * 2022-03-07 2025-04-29 씨제이제일제당 주식회사 변이형 l-쓰레오닌 배출 단백질 및 이를 이용한 l-쓰레오닌 생산 방법
KR102931070B1 (ko) * 2023-03-23 2026-02-26 씨제이제일제당 주식회사 변이형 트레오닌/호모세린 배출 단백질 및 이를 이용한 l-아미노산 생산 방법
KR102931069B1 (ko) * 2023-03-23 2026-02-26 씨제이제일제당 주식회사 변이형 트레오닌/호모세린 배출 단백질 및 이를 이용한 l-아미노산 생산 방법
KR20240143214A (ko) * 2023-03-23 2024-10-02 씨제이제일제당 (주) 변이형 트레오닌/호모세린 배출 단백질 및 이를 이용한 l-아미노산 생산 방법
CN116463304B (zh) * 2023-06-14 2023-09-05 黑龙江伊品生物科技有限公司 苏氨酸脱氢酶基因突变体及其应用
KR102893595B1 (ko) * 2024-02-29 2025-12-02 씨제이제일제당 주식회사 신규한 변이형 l-쓰레오닌 배출 단백질 및 이를 이용한 l-쓰레오닌 생산 방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2231772T3 (es) * 1992-08-10 2005-05-16 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Adn codante para la descarbamilasa con termoestabilidad mejorada y uso del mismo.
US5939307A (en) * 1996-07-30 1999-08-17 The Archer-Daniels-Midland Company Strains of Escherichia coli, methods of preparing the same and use thereof in fermentation processes for l-threonine production
JP4265093B2 (ja) * 2000-08-11 2009-05-20 味の素株式会社 スレオニン及びイソロイシンの製造法
KR100397423B1 (ko) 2001-02-13 2003-09-13 씨제이 주식회사 Ｌ-쓰레오닌의 제조방법
KR100426807B1 (ko) 2001-06-19 2004-04-13 씨제이 주식회사 엘-쓰레오닌 생산 미생물 및 이를 이용한 엘-쓰레오닌 제조방법
US20050032178A1 (en) 2002-07-10 2005-02-10 Degussa Ag Process for the fermentative preparation of L-amino acids using strains of the enterobacteriaceae family
DE10314618A1 (de) 2003-04-01 2004-10-14 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung von Stämmen der Familie Enterobacteriaceae
KR100498971B1 (ko) * 2003-04-04 2005-07-04 씨제이 주식회사 염색체 내 ｔｄｃＢＣ 및 ｐｃｋＡ 유전자가 불활성화된 미생물 및 이를 이용하여 Ｌ-쓰레오닌을 제조하는 방법
RU2376371C2 (ru) * 2003-06-18 2009-12-20 Дженелюкс Корпорейшн Модифицированные рекомбинантные вакцинирующие вирусы и другие микроорганизмы и их применение
KR100608084B1 (ko) 2004-02-05 2006-08-02 씨제이 주식회사 ｉｃｌＲ 유전자가 불활성화된 Ｌ-쓰레오닌을 생산하는 미생물, 그를 제조하는 방법 및 그를 이용한 Ｌ-쓰레오닌의 제조방법
KR100596372B1 (ko) 2004-12-06 2006-07-04 씨제이 주식회사 염색체 상의 ｌｙｓＲ유전자가 불활성화된 Ｌ-쓰레오닌생성 미생물, 그를 제조하는 방법 및 상기 미생물을이용한 Ｌ-쓰레오닌의 제조방법

Also Published As

Publication number Publication date
JP2009517088A (ja) 2009-04-30
KR20080082880A (ko) 2008-09-12
WO2008111708A1 (en) 2008-09-18
KR100858913B1 (ko) 2008-09-17
US8852898B2 (en) 2014-10-07
EP2121918B1 (de) 2011-09-28
EP2121918A4 (de) 2009-11-25
EP2121918A1 (de) 2009-11-25
US20110003349A1 (en) 2011-01-06
JP4846021B2 (ja) 2011-12-28

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