ATE526876T1 - Verfahren und gerät zur überwachung der intravenösen konzentration von medikamenten mittels ausatemluft - Google Patents

Verfahren und gerät zur überwachung der intravenösen konzentration von medikamenten mittels ausatemluft

Info

Publication number
ATE526876T1
ATE526876T1 AT03710743T AT03710743T ATE526876T1 AT E526876 T1 ATE526876 T1 AT E526876T1 AT 03710743 T AT03710743 T AT 03710743T AT 03710743 T AT03710743 T AT 03710743T AT E526876 T1 ATE526876 T1 AT E526876T1
Authority
AT
Austria
Prior art keywords
medication
monitoring
exhausted air
concentration
intravenous concentration
Prior art date
Application number
AT03710743T
Other languages
English (en)
Inventor
Richard J Melker
David G Bjoraker
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32823171&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE526876(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Florida filed Critical Univ Florida
Application granted granted Critical
Publication of ATE526876T1 publication Critical patent/ATE526876T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/083—Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption
    • A61B5/0836—Measuring rate of CO2 production
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4821—Determining level or depth of anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physiology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT03710743T 2003-01-23 2003-01-23 Verfahren und gerät zur überwachung der intravenösen konzentration von medikamenten mittels ausatemluft ATE526876T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2003/002287 WO2004066839A1 (en) 2003-01-23 2003-01-23 Method and apparatus for monitoring intravenous (iv) drug concentration using exhaled breath

Publications (1)

Publication Number Publication Date
ATE526876T1 true ATE526876T1 (de) 2011-10-15

Family

ID=32823171

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03710743T ATE526876T1 (de) 2003-01-23 2003-01-23 Verfahren und gerät zur überwachung der intravenösen konzentration von medikamenten mittels ausatemluft

Country Status (6)

Country Link
EP (2) EP2055233B1 (de)
JP (1) JP4773098B2 (de)
AT (1) ATE526876T1 (de)
AU (1) AU2003214900A1 (de)
ES (1) ES2369903T3 (de)
WO (1) WO2004066839A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050054942A1 (en) * 2002-01-22 2005-03-10 Melker Richard J. System and method for therapeutic drug monitoring
US20060062734A1 (en) * 2004-09-20 2006-03-23 Melker Richard J Methods and systems for preventing diversion of prescription drugs
JP2007198829A (ja) * 2006-01-25 2007-08-09 Kao Corp 経血臭判定指標剤
US20070224128A1 (en) * 2006-03-07 2007-09-27 Donn Michael Dennis Drug adherence monitoring system
US20120143515A1 (en) * 2006-09-28 2012-06-07 Smiths Detection Inc. Multi-detector gas identification system
JP4854490B2 (ja) * 2006-12-11 2012-01-18 大塚製薬株式会社 １３ｃ−呼気試験を用いた麻酔深度の測定方法
DE102012203897B4 (de) 2012-03-13 2014-11-27 Kist Europe Forschungsgesellschaft Mbh Vorrichtung zur Durchführung einer Anästhesie oder Analgosedierung und Verfahren zum Betreiben einer Vorrichtung zur Durchführung einer Anästhesie oder Analgosedierung
CN103048382B (zh) * 2012-12-21 2015-02-11 浙江大学 在线监测异丙酚麻醉药的系统和方法
WO2014173558A1 (en) 2013-04-24 2014-10-30 Fresenius Kabi Deutschland Gmbh Method of operating a control device for controlling an infusion device
EP3224616B1 (de) * 2014-11-27 2020-04-22 Koninklijke Philips N.V. Chemische analyse von urin- und fäkalienausdünstungen
CN108801678B (zh) * 2018-06-27 2020-10-16 楚广民 一种改进型多功能病理取样切片装置
CN112533533B (zh) * 2018-08-07 2024-04-12 罗斯特姆医疗创新有限公司 用于监测不与患者的通气肺相互作用的血流的系统和方法
CN114431898B (zh) * 2021-12-23 2024-06-04 新绎健康科技有限公司 基于呼吸气的酮体检测装置
US20250216369A1 (en) * 2022-03-23 2025-07-03 Becton, Dickinson And Company Gas Detection, Identification, and Quantification Systems and Devices for Medical Applications
DE102025116826A1 (de) * 2024-05-27 2025-11-27 Löwenstein Medical Technology S.A. Schätzen einer Konzentration eines Atemgases im Blut eines Patienten
CN119818764B (zh) * 2024-12-23 2025-09-23 江苏省人民医院（南京医科大学第一附属医院） 基于ai与有创血压监测的血管活性药物注射系统

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4202352A (en) 1978-04-06 1980-05-13 Research Development Corporation Apparatus for measurement of expired gas concentration in infants
US4312228A (en) 1979-07-30 1982-01-26 Henry Wohltjen Methods of detection with surface acoustic wave and apparati therefor
DE3344274A1 (de) 1982-12-07 1984-06-07 Canon K.K., Tokio/Tokyo Bildaufnahme-einrichtung mit einer belichtungssteuereinrichtung
US5034192A (en) 1984-11-23 1991-07-23 Massachusetts Institute Of Technology Molecule-based microelectronic devices
EP0265834B1 (de) 1986-10-28 1992-07-22 Figaro Engineering Inc. Fühler und Verfahren zu dessen Herstellung
US4796639A (en) 1987-11-05 1989-01-10 Medical Graphics Corporation Pulmonary diagnostic system
US5003985A (en) * 1987-12-18 1991-04-02 Nippon Colin Co., Ltd. End tidal respiratory monitor
US4992244A (en) 1988-09-27 1991-02-12 The United States Of America As Represented By The Secretary Of The Navy Films of dithiolene complexes in gas-detecting microsensors
US4895017A (en) 1989-01-23 1990-01-23 The Boeing Company Apparatus and method for early detection and identification of dilute chemical vapors
US5081871A (en) 1989-02-02 1992-01-21 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Breath sampler
EP0398286A3 (de) 1989-05-18 1991-09-25 Nisshinbo Industries, Inc. Ammoniak-Fühler
US5071770A (en) 1989-09-05 1991-12-10 The United States Of America As Represented By The Secretary Of The Air Force Method for gaseous component indentification with #3 polymeric film
US5042501A (en) 1990-05-01 1991-08-27 Battelle Memorial Institute Apparatus and method for analysis of expired breath
US5145645A (en) 1990-06-15 1992-09-08 Spectral Sciences, Inc. Conductive polymer selective species sensor
JP3240171B2 (ja) * 1992-01-27 2001-12-17 日機装株式会社 麻酔監視装置
US5468467A (en) * 1993-04-23 1995-11-21 Bracco International B.V. Methods for the in vivo measurement of the concentration of non-imaging nmr-detectable xenobiotic compounds
FR2710153B1 (fr) 1993-09-17 1995-12-01 Alpha Mos Sa Procédés et appareils de détection des substances odorantes et applications.
DE69428173T2 (de) 1993-09-30 2002-03-28 Nittan Co., Ltd. Sensorvorrichtung und elektronische Anlage mit eingebauter Sensorvorrichtung
US5605612A (en) 1993-11-11 1997-02-25 Goldstar Electron Co., Ltd. Gas sensor and manufacturing method of the same
DE4423289C1 (de) 1994-07-02 1995-11-02 Karlsruhe Forschzent Gassensor für reduzierende oder oxidierende Gase
US5865784A (en) * 1995-06-07 1999-02-02 Alliance Pharmaceutical Corp. Method of hemodilution facilitated by monitoring oxygenation status
FI102511B (fi) 1995-06-26 1998-12-31 Instrumentarium Oy Pitoisuusmittaus hengitysilmasta
JPH0954040A (ja) * 1995-08-09 1997-02-25 Kdk Corp 呼気中成分の光学的測定方法
US5945069A (en) 1996-03-21 1999-08-31 California Institute Of Technology Gas sensor test chip
JPH09271516A (ja) * 1996-04-05 1997-10-21 Nippon Koden Corp 麻酔深度判定方法及び装置
US6010459A (en) 1996-04-09 2000-01-04 Silkoff; Philip E. Method and apparatus for the measurement of components of exhaled breath in humans
US5756879A (en) 1996-07-25 1998-05-26 Hughes Electronics Volatile organic compound sensors
SE519902C2 (sv) * 1996-11-06 2003-04-22 Servotek Ab Sätt och apparat för att indirekt bestämma koncentrationen av ett förutbestämt ämne i blodet
DE19709704C2 (de) * 1997-03-10 1999-11-04 Michael Georgieff Verwendung einer flüssigen Präparation von Xenon zur intravenösen Verabreichung bei Einleitung und/oder Aufrechterhaltung der Anaesthesie
US6186977B1 (en) 1997-04-24 2001-02-13 Joseph L. Riley Anesthesia Associates Apparatus and method for total intravenous anesthesia delivery and associated patient monitoring
AU8131198A (en) * 1997-07-15 1999-02-10 Daiichi Pharmaceutical Co., Ltd. Prophylactic or therapeutic agent for amnesia
EP1082056B1 (de) * 1998-06-03 2007-11-14 Scott Laboratories, Inc. Gerät zur linderung von schmerz bei bewusstsein und angstzuständen im zusammenhang mit medizinischen und chirurgischen eingriffen
US6319724B1 (en) * 1998-06-19 2001-11-20 Cyrano Sciences, Inc. Trace level detection of analytes using artificial olfactometry
US6286360B1 (en) * 1999-02-25 2001-09-11 Metasensors, Inc. Methods and apparatus for real time fluid analysis
NZ518740A (en) * 1999-11-08 2004-04-30 Univ Florida Marker detection method and apparatus to monitor drug compliance
US6609068B2 (en) * 2000-02-22 2003-08-19 Dow Global Technologies Inc. Personal computer breath analyzer for health-related behavior modification and method
AU2001275290A1 (en) * 2000-06-07 2001-12-17 Healthetech, Inc. Breath ketone analyzer
US6938619B1 (en) * 2000-06-13 2005-09-06 Scott Laboratories, Inc. Mask free delivery of oxygen and ventilatory monitoring
WO2001097779A2 (en) * 2000-06-16 2001-12-27 Rtp Pharma Inc. Improved injectable dispersions of propofol
JP2002136569A (ja) * 2000-11-02 2002-05-14 Motoharu Sakai 足裏押圧具
US20020160043A1 (en) * 2001-02-27 2002-10-31 Dennis Coleman Compositions and method of manufacture for oral dissolvable dosage forms
US7076371B2 (en) * 2001-03-03 2006-07-11 Chi Yung Fu Non-invasive diagnostic and monitoring method and apparatus based on odor detection
US6631291B2 (en) * 2001-05-18 2003-10-07 Instrumentarium Corp. Closed loop drug administration method and apparatus using EEG complexity for control purposes
WO2002095359A2 (en) * 2001-05-23 2002-11-28 University Of Florida Method and apparatus for detecting illicit substances

Also Published As

Publication number Publication date
WO2004066839A1 (en) 2004-08-12
EP2055233B1 (de) 2012-10-10
AU2003214900A1 (en) 2004-08-23
JP4773098B2 (ja) 2011-09-14
EP2055233A1 (de) 2009-05-06
ES2369903T3 (es) 2011-12-09
EP1610681B1 (de) 2011-10-05
EP1610681A1 (de) 2006-01-04
JP2006513435A (ja) 2006-04-20

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Denisco Comments by Richard A. Denisco

Legal Events

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