ATE268477T1 - Verfahren, reagenz und messkartusche zur bestimmung der gerinnungszeit - Google Patents
Verfahren, reagenz und messkartusche zur bestimmung der gerinnungszeitInfo
- Publication number
- ATE268477T1 ATE268477T1 AT00957770T AT00957770T ATE268477T1 AT E268477 T1 ATE268477 T1 AT E268477T1 AT 00957770 T AT00957770 T AT 00957770T AT 00957770 T AT00957770 T AT 00957770T AT E268477 T1 ATE268477 T1 AT E268477T1
- Authority
- AT
- Austria
- Prior art keywords
- reagent
- clotting time
- heparin
- measuring cartridge
- determining clotting
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 4
- 206010053567 Coagulopathies Diseases 0.000 title abstract 3
- 230000035602 clotting Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 abstract 4
- 229960002897 heparin Drugs 0.000 abstract 4
- 229920000669 heparin Polymers 0.000 abstract 4
- 102000002262 Thromboplastin Human genes 0.000 abstract 2
- 108010000499 Thromboplastin Proteins 0.000 abstract 2
- 239000008280 blood Substances 0.000 abstract 2
- 210000004369 blood Anatomy 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/108331—Preservative, buffer, anticoagulant or diluent
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15245099P | 1999-09-03 | 1999-09-03 | |
| PCT/US2000/023249 WO2001018551A1 (en) | 1999-09-03 | 2000-08-24 | Method, reagent and test cartridge for determining clotting time |
| US09/645,786 US6699718B1 (en) | 1999-09-03 | 2000-08-24 | Method, reagent and test cartridge for determining clotting time |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE268477T1 true ATE268477T1 (de) | 2004-06-15 |
Family
ID=22542977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00957770T ATE268477T1 (de) | 1999-09-03 | 2000-08-24 | Verfahren, reagenz und messkartusche zur bestimmung der gerinnungszeit |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US6699718B1 (de) |
| EP (1) | EP1208383B1 (de) |
| AT (1) | ATE268477T1 (de) |
| AU (1) | AU6933900A (de) |
| CA (1) | CA2382143C (de) |
| DE (1) | DE60011274T2 (de) |
| ES (1) | ES2222228T3 (de) |
| WO (1) | WO2001018551A1 (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6933900A (en) | 1999-09-03 | 2001-04-10 | Roche Diagnostics Corporation | Method, reagent and test cartridge for determining clotting time |
| US6448024B1 (en) * | 2000-10-03 | 2002-09-10 | Roche Diagnostics Corporation | Method, reagent, cartridge, and device for determining fibrinogen |
| JP3905833B2 (ja) * | 2002-12-27 | 2007-04-18 | 伊那食品工業株式会社 | 増粘用添加物 |
| EP1745145A4 (de) * | 2004-05-11 | 2008-03-26 | Heptest Lab Inc | Zusammensetzung, kit und einstufiges verfahren zur überwachung von verbindungen mit anti-faktor-xa- und/oder anti-faktor-iia-wirkungen |
| US7674616B2 (en) * | 2006-09-14 | 2010-03-09 | Hemosense, Inc. | Device and method for measuring properties of a sample |
| US20080114549A1 (en) * | 2006-11-09 | 2008-05-15 | Mark Evan Schafer | Rapid response blood analyzer |
| US20080297169A1 (en) * | 2007-05-31 | 2008-12-04 | Greenquist Alfred C | Particle Fraction Determination of A Sample |
| EP2040073A1 (de) | 2007-09-20 | 2009-03-25 | Iline Microsystems, S.L. | Mikrofluidische Vorrichtung und Verfahren zur Flüssigkeitsgerinnungs-Zeitbestimmung |
| US8448499B2 (en) | 2008-12-23 | 2013-05-28 | C A Casyso Ag | Cartridge device for a measuring system for measuring viscoelastic characteristics of a sample liquid, a corresponding measuring system, and a corresponding method |
| US20100285583A1 (en) * | 2009-05-08 | 2010-11-11 | Capelluto Daniel G S | Compounds and methods for inhibiting platelet aggregation |
| WO2011094279A1 (en) * | 2010-01-26 | 2011-08-04 | The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations | Planar labyrinth micromixer systems and methods |
| EP2371284A1 (de) | 2010-03-24 | 2011-10-05 | C A Casyso AG | Verfahren und Vorrichtung zur Bestimmung von mindestens einem Auswertungsparameter einer Blutprobe |
| US9518905B2 (en) | 2012-01-16 | 2016-12-13 | Abram Scientific, Inc. | Methods, devices, and systems for measuring physical properties of fluid |
| CN107083319B (zh) | 2012-03-16 | 2026-01-16 | 统计诊断与创新有限公司 | 具有集成传送模块的测试盒 |
| US9075042B2 (en) | 2012-05-15 | 2015-07-07 | Wellstat Diagnostics, Llc | Diagnostic systems and cartridges |
| US9213043B2 (en) | 2012-05-15 | 2015-12-15 | Wellstat Diagnostics, Llc | Clinical diagnostic system including instrument and cartridge |
| US9625465B2 (en) | 2012-05-15 | 2017-04-18 | Defined Diagnostics, Llc | Clinical diagnostic systems |
| US10539579B2 (en) | 2014-09-29 | 2020-01-21 | C A Casyso Gmbh | Blood testing system and method |
| US9897618B2 (en) | 2014-09-29 | 2018-02-20 | C A Casyso Gmbh | Blood testing system |
| US10288630B2 (en) | 2014-09-29 | 2019-05-14 | C A Casyso Gmbh | Blood testing system and method |
| US10816559B2 (en) | 2014-09-29 | 2020-10-27 | Ca Casyso Ag | Blood testing system and method |
| US10175225B2 (en) | 2014-09-29 | 2019-01-08 | C A Casyso Ag | Blood testing system and method |
| USD777343S1 (en) | 2015-05-28 | 2017-01-24 | C A Casyso Ag | Body fluid cartridge device |
| US10295554B2 (en) | 2015-06-29 | 2019-05-21 | C A Casyso Gmbh | Blood testing system and method |
| DE202015104762U1 (de) * | 2015-09-08 | 2016-12-09 | Jürgen Schulz | Kartusche für eine Koagulationsmessung |
| US10473674B2 (en) | 2016-08-31 | 2019-11-12 | C A Casyso Gmbh | Controlled blood delivery to mixing chamber of a blood testing cartridge |
| US10843185B2 (en) | 2017-07-12 | 2020-11-24 | Ca Casyso Gmbh | Autoplatelet cartridge device |
| WO2020163213A1 (en) | 2019-02-04 | 2020-08-13 | Abram Scientific, Inc. | Fluid property measurement devices and methods |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3311287A1 (de) | 1983-03-28 | 1984-10-04 | Behringwerke Ag, 3550 Marburg | Verfahren zur fotometrischen bestimmung der aktivierten partiellen thromboplastinzeit und reagenz dazu |
| DE3407280A1 (de) | 1984-02-28 | 1985-09-19 | Gödecke AG, 1000 Berlin | Testsatz zur bestimmung der aktivierten partiellen thromboplastinzeit (ptt) mit erhoehter heparinempfindlichkeit |
| DE3504405A1 (de) * | 1985-02-08 | 1986-08-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Bestimmung von prokallikrein |
| US4666831A (en) | 1985-02-19 | 1987-05-19 | The Liposome Company, Inc. | Lipid-dependent diagnostic assays |
| US4756884A (en) | 1985-08-05 | 1988-07-12 | Biotrack, Inc. | Capillary flow device |
| US5164598A (en) | 1985-08-05 | 1992-11-17 | Biotrack | Capillary flow device |
| US4946775A (en) | 1985-09-05 | 1990-08-07 | Yin E Thye | Composition, kit and method for assaying heparin and a method for making the composition |
| US4755461A (en) | 1986-04-17 | 1988-07-05 | Bio/Data Corporation | Tableted blood plasma microconcentrated thromboplastin coagulation reagent |
| US5039617A (en) | 1989-04-20 | 1991-08-13 | Biotrack, Inc. | Capillary flow device and method for measuring activated partial thromboplastin time |
| US5314695A (en) * | 1990-11-13 | 1994-05-24 | Corvas International, Inc. | Tissue factor based prothrombin time reagent |
| AT395597B (de) | 1991-01-25 | 1993-01-25 | Immuno Ag | Reagens zur bestimmung von faktor viii-aktivitaet |
| US5254350A (en) | 1991-07-22 | 1993-10-19 | Helena Laboratories Corporation | Method of preparing a thromboplastin extract |
| JP3180824B2 (ja) | 1991-08-30 | 2001-06-25 | シスメックス株式会社 | 血液凝固試薬 |
| ATE163768T1 (de) * | 1991-10-04 | 1998-03-15 | Dade Int Inc | Herstellung von prothrombinzeit-reagenzien aus rekombinantem menschlichem gewebefaktor und sythetischen phospholipiden |
| ES2130244T3 (es) * | 1992-05-15 | 1999-07-01 | Immuno Ag | Reactivo para la determinacion del tiempo de tromboplastina parcialmente activa (iipa). |
| US5443959A (en) | 1992-09-09 | 1995-08-22 | Tokuyama Corporation | Method of assaying fibrinogen, dry reagent therefor, and process for the preparation thereof |
| US5472852A (en) | 1993-09-15 | 1995-12-05 | Oklahoma Medical Research Foundation | Assay for detection of selective Protein C inhibition by patients |
| EP0677171B1 (de) | 1993-11-04 | 2000-03-29 | Dade Behring Inc. | Tetrahydroxychinon als eine aktivatorkomponente für den aktivierten partiellen thromboplastinzeit-test der blutgerinnung und als anzeiger von blutgerinnungsstörungen |
| US5589571A (en) | 1994-10-28 | 1996-12-31 | Cor Therapeutics, Inc. | Process for production of inhibited forms of activated blood factors |
| US5705395A (en) | 1994-11-14 | 1998-01-06 | The Scripps Research Institute | Method for diagnosis of thrombotic disorders |
| DE69832628T2 (de) * | 1997-04-23 | 2006-09-07 | Instrumentation Laboratory S.P.A. | Rekombinant-kaninchengewebefaktor basiertes prothrombinzeitreagenz |
| US6183979B1 (en) * | 1999-03-24 | 2001-02-06 | International Technidyne Corporation | Preparation of dried synthetic prothrombin time reagents |
| AU6933900A (en) * | 1999-09-03 | 2001-04-10 | Roche Diagnostics Corporation | Method, reagent and test cartridge for determining clotting time |
-
2000
- 2000-08-24 AU AU69339/00A patent/AU6933900A/en not_active Abandoned
- 2000-08-24 DE DE60011274T patent/DE60011274T2/de not_active Expired - Fee Related
- 2000-08-24 EP EP00957770A patent/EP1208383B1/de not_active Expired - Lifetime
- 2000-08-24 US US09/645,786 patent/US6699718B1/en not_active Expired - Fee Related
- 2000-08-24 CA CA002382143A patent/CA2382143C/en not_active Expired - Fee Related
- 2000-08-24 WO PCT/US2000/023249 patent/WO2001018551A1/en not_active Ceased
- 2000-08-24 AT AT00957770T patent/ATE268477T1/de not_active IP Right Cessation
- 2000-08-24 ES ES00957770T patent/ES2222228T3/es not_active Expired - Lifetime
-
2003
- 2003-09-18 US US10/666,421 patent/US20040077097A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2382143A1 (en) | 2001-03-15 |
| EP1208383A1 (de) | 2002-05-29 |
| ES2222228T3 (es) | 2005-02-01 |
| DE60011274T2 (de) | 2005-07-07 |
| DE60011274D1 (de) | 2004-07-08 |
| EP1208383B1 (de) | 2004-06-02 |
| US20040077097A1 (en) | 2004-04-22 |
| WO2001018551A1 (en) | 2001-03-15 |
| US6699718B1 (en) | 2004-03-02 |
| CA2382143C (en) | 2005-10-18 |
| AU6933900A (en) | 2001-04-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |