ATE526953T1 - Verwendung von 5-ht7-rezeptor-agonisten zur behandlung von schmerzen - Google Patents
Verwendung von 5-ht7-rezeptor-agonisten zur behandlung von schmerzenInfo
- Publication number
- ATE526953T1 ATE526953T1 AT07785870T AT07785870T ATE526953T1 AT E526953 T1 ATE526953 T1 AT E526953T1 AT 07785870 T AT07785870 T AT 07785870T AT 07785870 T AT07785870 T AT 07785870T AT E526953 T1 ATE526953 T1 AT E526953T1
- Authority
- AT
- Austria
- Prior art keywords
- receptor agonists
- pain
- treat pain
- symptoms
- neuropathic pain
- Prior art date
Links
- 208000002193 Pain Diseases 0.000 title abstract 4
- 108091005436 5-HT7 receptors Proteins 0.000 title abstract 2
- 239000000018 receptor agonist Substances 0.000 title abstract 2
- 229940044601 receptor agonist Drugs 0.000 title abstract 2
- 208000004296 neuralgia Diseases 0.000 abstract 3
- 208000021722 neuropathic pain Diseases 0.000 abstract 3
- 208000024891 symptom Diseases 0.000 abstract 2
- 208000004454 Hyperalgesia Diseases 0.000 abstract 1
- 206010053552 allodynia Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06013496A EP1875899A1 (de) | 2006-06-29 | 2006-06-29 | Verwendugng von Agonisten des 5HT7 Rezeptors in der Behandlung von Schmerzen |
| PCT/EP2007/005776 WO2008000495A1 (de) | 2006-06-29 | 2007-06-29 | Use of 5-ht7 receptor agonists for the treatment of pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE526953T1 true ATE526953T1 (de) | 2011-10-15 |
Family
ID=37308928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT07785870T ATE526953T1 (de) | 2006-06-29 | 2007-06-29 | Verwendung von 5-ht7-rezeptor-agonisten zur behandlung von schmerzen |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090326014A1 (de) |
| EP (2) | EP1875899A1 (de) |
| AT (1) | ATE526953T1 (de) |
| ES (1) | ES2374739T3 (de) |
| WO (1) | WO2008000495A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9220054B2 (en) | 2009-12-22 | 2015-12-22 | Intel Corporation | Enhanced service discovery mechanism in wireless communication system |
| EP2676954A1 (de) | 2012-06-19 | 2013-12-25 | Laboratorios del Dr. Esteve S.A. | Heterocyclyl-substituierte Phenylderivate als Vasodilatoren |
| WO2014164756A1 (en) | 2013-03-11 | 2014-10-09 | Temple University Of The Commonwealth System Of Higher Education | Novel 5-hydroxytryptamine receptor 7 activity modulators and their method of use |
| WO2016040554A1 (en) | 2014-09-10 | 2016-03-17 | Temple University-Of The Commonwealth System Of Higher Education | Novel 5-hydroxytryptamine receptor 7 activity modulators and their method of use |
| ES3050660T3 (en) | 2016-11-15 | 2025-12-22 | Univ Temple | 3-(2-(4-phenylpiperazin-1-yl)ethyl)-2-oxa-8-azaspiro[4.5]decan-1-one derivatives and related compounds as 5-hydroxytryptamine receptor 7 (5-ht7) modulators for treating e.g. inflammatory bowel disease, circadian rhythm disorder or depression |
| US11220505B2 (en) | 2017-03-21 | 2022-01-11 | Temple University-Of The Commonwealth System Of Higher Education | 5-hydroxytryptamine receptor 7 modulators and their use as therapeutic agents |
| MA52567A (fr) | 2018-05-11 | 2021-03-17 | Praeventix Llc | Nouveaux lactames fonctionnalisés en tant que modulateurs du récepteur de 5-hydroxytryptamine 7 et leur procédé d'utilisation |
| EP3870292A4 (de) | 2018-10-26 | 2022-11-09 | The Research Foundation for The State University of New York | Kombination von serotonin-spezifischem wiederaufnahmeinhibitor und serotonin-1a-rezeptor-partialagonist zur verminderung von l-dopa-induzierter dyskinesie |
| WO2021097117A2 (en) | 2019-11-13 | 2021-05-20 | Temple University-Of The Commonwealth System Of Higher Education | Novel functionalized lactones as modulators of the 5-hydroxytryptamine receptor 7 and their method of use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19542281C2 (de) * | 1995-11-14 | 1997-12-04 | Boehringer Ingelheim Kg | Verwendung von Epinastin für die Behandlung der Migräne |
| EP1222185A1 (de) * | 1999-10-18 | 2002-07-17 | Smithkline Beecham Plc | Tetrahydrobenzindolon-derivate, deren herstellung und deren verwendung als 5-ht7 rezeptor antagonisten |
| ATE315023T1 (de) * | 2000-10-30 | 2006-02-15 | Warner Lambert Co | Aminoalkylpyrrolidine als serotoninrezeptorliganden sowie diese enthaltende zusammensetzungen, pharmazeutische verwendungen und methoden zu deren synthese |
| EP1676840A1 (de) * | 2004-12-28 | 2006-07-05 | Laboratorios Del Dr. Esteve, S.A. | 5-HT7-Rezeptorantagonisten |
| EP1634081A2 (de) * | 2003-05-28 | 2006-03-15 | Bayer HealthCare AG | Diagnostika und therapeutika für krankheiten, die mit dem 5-hydroxytryptamin (serotonin) receptor 7 (5-ht7) assoziiert sind |
| GB0316128D0 (en) * | 2003-07-10 | 2003-08-13 | Univ Aston | Novel sulfonamide compounds |
| ES2257168B1 (es) * | 2004-08-18 | 2007-06-01 | Laboratorios Del Dr Esteve, S.A. | Ligandos del receptor 5-ht7. |
-
2006
- 2006-06-29 EP EP06013496A patent/EP1875899A1/de not_active Withdrawn
-
2007
- 2007-06-29 ES ES07785870T patent/ES2374739T3/es active Active
- 2007-06-29 EP EP07785870A patent/EP2049090B1/de not_active Not-in-force
- 2007-06-29 AT AT07785870T patent/ATE526953T1/de not_active IP Right Cessation
- 2007-06-29 US US12/308,923 patent/US20090326014A1/en not_active Abandoned
- 2007-06-29 WO PCT/EP2007/005776 patent/WO2008000495A1/de not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP2049090B1 (de) | 2011-10-05 |
| EP2049090A1 (de) | 2009-04-22 |
| US20090326014A1 (en) | 2009-12-31 |
| EP1875899A1 (de) | 2008-01-09 |
| WO2008000495A1 (de) | 2008-01-03 |
| ES2374739T3 (es) | 2012-02-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |