UA101478C2 - Соединения, полезные как ингибиторы raf-киназы - Google Patents

Соединения, полезные как ингибиторы raf-киназы

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Publication number
UA101478C2
UA101478C2 UAA200913589A UAA200913589A UA101478C2 UA 101478 C2 UA101478 C2 UA 101478C2 UA A200913589 A UAA200913589 A UA A200913589A UA A200913589 A UAA200913589 A UA A200913589A UA 101478 C2 UA101478 C2 UA 101478C2
Authority
UA
Ukraine
Prior art keywords
inhibitors
protein kinase
compounds useful
raf protein
raf
Prior art date
Application number
UAA200913589A
Other languages
English (en)
Ukrainian (uk)
Inventor
Вейжун Чень
Дженніфер Коссроу
Ллойд Франклін
Бін Гуань
Джон Ховард ДЖОУНЗ
Гнанасамбандам Кумаравел
Бенджамін Лейн
Адам Літтке
Алєксєй Луговской
Хайжо Пен
Ноель Пауелл
Брайан РАЙМУНДО
Хіроко Танака
Джеффрі Весселз
Томас Уінн
Чжилі Сінь
Original Assignee
Санесіс Фармасьютікалз, Інк.
Байоджен Айдек Ма Інк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40029124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA101478(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Санесіс Фармасьютікалз, Інк., Байоджен Айдек Ма Інк. filed Critical Санесіс Фармасьютікалз, Інк.
Publication of UA101478C2 publication Critical patent/UA101478C2/ru

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    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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Abstract

Данное изобретение касается карбоксамидных производных пиримидина, полезных в качестве ингибиторов Raf-протеинкиназы. Данное изобретение также касается композиций, содержащих упомянутые соединения, и способов лечения Raf-опосредствованных заболеваний.
UAA200913589A 2007-06-29 2008-06-30 Соединения, полезные как ингибиторы raf-киназы UA101478C2 (ru)

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US9920048B2 (en) 2018-03-20
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JP2010532380A (ja) 2010-10-07
BRPI0813499B1 (pt) 2020-02-11
EP2167489A2 (en) 2010-03-31
US9556177B2 (en) 2017-01-31
KR20160027992A (ko) 2016-03-10
WO2009006389A8 (en) 2009-03-26
BRPI0813499A2 (pt) 2015-01-06
CN104370828B (zh) 2017-01-18
ES2635729T3 (es) 2017-10-04
US20090036419A1 (en) 2009-02-05
TW200916467A (en) 2009-04-16
KR20100033384A (ko) 2010-03-29
DK3231798T3 (da) 2020-01-20
IL202835A0 (en) 2010-06-30
RU2492166C2 (ru) 2013-09-10
JP2013256534A (ja) 2013-12-26
EP3231798A1 (en) 2017-10-18
TWI444379B (zh) 2014-07-11
IL202835A (en) 2014-12-31
CN106957314A (zh) 2017-07-18
NZ582352A (en) 2012-06-29
CN104370828A (zh) 2015-02-25
AU2008273002B2 (en) 2013-10-03
AU2008273002A1 (en) 2009-01-08
WO2009006389A2 (en) 2009-01-08
US8802657B2 (en) 2014-08-12
AR067354A1 (es) 2009-10-07
JP5649445B2 (ja) 2015-01-07
CA2693182A1 (en) 2009-01-08
KR101764076B1 (ko) 2017-08-01
CN101784545B (zh) 2016-04-20
CN106957314B (zh) 2019-12-31

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