ATE526957T1 - Hemmung der biofilmbildung - Google Patents
Hemmung der biofilmbildungInfo
- Publication number
- ATE526957T1 ATE526957T1 AT10002928T AT10002928T ATE526957T1 AT E526957 T1 ATE526957 T1 AT E526957T1 AT 10002928 T AT10002928 T AT 10002928T AT 10002928 T AT10002928 T AT 10002928T AT E526957 T1 ATE526957 T1 AT E526957T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibition
- biofilm formation
- ybik
- cysd
- cysj
- Prior art date
Links
- 230000032770 biofilm formation Effects 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 101100232366 Escherichia coli (strain K12) iaaA gene Proteins 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 101150058227 cysB gene Proteins 0.000 abstract 1
- 101150052442 cysD gene Proteins 0.000 abstract 1
- 101150100268 cysI gene Proteins 0.000 abstract 1
- 101150036205 cysJ gene Proteins 0.000 abstract 1
- 101150094831 cysK gene Proteins 0.000 abstract 1
- 101150112941 cysK1 gene Proteins 0.000 abstract 1
- 101150029709 cysM gene Proteins 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/28—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Vibrionaceae (F)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58768004P | 2004-07-14 | 2004-07-14 | |
| US60976304P | 2004-09-14 | 2004-09-14 | |
| US11/085,279 US7604978B2 (en) | 2004-07-14 | 2005-03-21 | Inhibition of biofilm formation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE526957T1 true ATE526957T1 (de) | 2011-10-15 |
Family
ID=35599971
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT10002928T ATE526957T1 (de) | 2004-07-14 | 2005-07-14 | Hemmung der biofilmbildung |
| AT05791359T ATE462793T1 (de) | 2004-07-14 | 2005-07-14 | Hemmung von biofilmbildung |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05791359T ATE462793T1 (de) | 2004-07-14 | 2005-07-14 | Hemmung von biofilmbildung |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7604978B2 (de) |
| EP (2) | EP1771558B1 (de) |
| AT (2) | ATE526957T1 (de) |
| CA (1) | CA2573440A1 (de) |
| DE (1) | DE602005020303D1 (de) |
| DK (2) | DK2213287T3 (de) |
| ES (2) | ES2374152T3 (de) |
| WO (1) | WO2006019926A2 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060264411A1 (en) * | 2005-05-20 | 2006-11-23 | Eldridge Gary R | Control of biofilm formation |
| US20060014285A1 (en) * | 2004-07-14 | 2006-01-19 | Eldridge Gary R | Methods and compositions for inhibiting biofilms |
| US7604978B2 (en) | 2004-07-14 | 2009-10-20 | Sequoia Sciences, Inc. | Inhibition of biofilm formation |
| CA2580078A1 (en) | 2004-09-14 | 2006-03-23 | Gary R. Eldridge | Compounds, compositions and methods for controlling biofilms and bacterial infections |
| US9919014B2 (en) * | 2005-04-05 | 2018-03-20 | Membrane Protective Technologies, Inc. | Reproductive cell maintenance system |
| US11857588B2 (en) | 2005-04-05 | 2024-01-02 | Membrane Protective Technologies, Inc. | Reproductive cell maintenance system |
| US20060228384A1 (en) * | 2005-04-06 | 2006-10-12 | Sequoia Sciences, Inc. | Control of biofilm with a biofilm inhibitor |
| US20070014739A1 (en) * | 2005-07-14 | 2007-01-18 | Eldridge Gary R | Compositions and methods for controlling biofilms and bacterial infections |
| ES2568730T3 (es) | 2010-10-06 | 2016-05-04 | The Board Of Trustees Of The University Of Arkansas | Composiciones anti-biopelícula y métodos de uso |
| US8324264B1 (en) | 2011-07-22 | 2012-12-04 | Sequoia Sciences, Inc. | Inhibitors of bacterial biofilms and related methods |
| WO2014193410A1 (en) | 2013-05-31 | 2014-12-04 | Empire Technology Development Llc | Method and device for detecting device colonization |
| WO2014193401A1 (en) | 2013-05-31 | 2014-12-04 | Empire Technology Development Llc | Color change indicator of biofilm formation |
| WO2019046409A1 (en) | 2017-08-30 | 2019-03-07 | Ecolab Usa Inc. | MOLECULES HAVING A HYDROPHOBIC GROUP AND TWO IDENTICAL HYDROPHILIC IONIC GROUPS AND CORRESPONDING COMPOSITIONS |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| CA3110686C (en) | 2018-08-29 | 2025-11-04 | Ecolab Usa Inc. | IONIC COMPOUNDS WITH MULTIPLE CHARGES DERIVED FROM POLYAMINES AND COMPOSITIONS BASED ON THESE COMPOUNDS AND ASSOCIATED PREPARATION PROCESSES |
| WO2020047181A1 (en) | 2018-08-29 | 2020-03-05 | Ecolab Usa Inc. | Use of multiple charged ionic compounds derived from polyamines for waste water clarification |
| CN116082183A (zh) | 2018-08-29 | 2023-05-09 | 埃科莱布美国股份有限公司 | 衍生自多胺的带多个电荷的离子化合物及其组合物和其作为反相破乳剂用于油气操作的用途 |
| CN113365498B (zh) | 2019-01-29 | 2022-10-25 | 埃科莱布美国股份有限公司 | 阳离子糖基化合物用于在水系统中进行微生物结垢控制的用途 |
| KR102486905B1 (ko) * | 2019-03-05 | 2023-01-11 | 연세대학교 산학협력단 | 항균제 내성 균주의 내성 극복용 약학 조성물 |
| CA3136427C (en) | 2019-04-16 | 2023-10-24 | Ecolab Usa Inc. | Use of multiple charged cationic compounds derived from polyamines and compositions thereof for corrosion inhibition in a water system |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3996132A (en) | 1974-07-18 | 1976-12-07 | Ortho Pharmaceutical Corporation | Purification of utero-evacuant extracts from plant substances |
| JPS6136213A (ja) | 1984-07-27 | 1986-02-20 | Rooto Seiyaku Kk | 口腔用組成物 |
| US5075109A (en) | 1986-10-24 | 1991-12-24 | Southern Research Institute | Method of potentiating an immune response |
| JPH06880Y2 (ja) * | 1986-12-10 | 1994-01-05 | 三洋電機株式会社 | 基板支持装置 |
| US4897268A (en) | 1987-08-03 | 1990-01-30 | Southern Research Institute | Drug delivery system and method of making the same |
| US4929365A (en) | 1989-09-18 | 1990-05-29 | Phillips Petroleum Co. | Biofilm control |
| WO1992019286A1 (en) | 1991-05-03 | 1992-11-12 | University Technologies International, Inc. | Biofilm reduction method |
| US6004438A (en) | 1991-12-31 | 1999-12-21 | 3M Innovative Properties Company | Biofilm reduction sterilizer |
| CN1067976C (zh) | 1994-12-03 | 2001-07-04 | 东国制药株式会社 | 积雪草酸衍生物及其制备方法和包含该衍生物的皮科制剂 |
| US5985601A (en) | 1995-06-05 | 1999-11-16 | Human Genome Sciences, Inc. | DNA encoding human cystatin E |
| US5789239A (en) | 1995-06-05 | 1998-08-04 | Betzdearborn Inc. | Composition and process for the avoidance of slime formation and/or for the removal of biofilm in water-bearing systems |
| US5882916A (en) | 1996-02-15 | 1999-03-16 | Nouveau Technolgies, Inc. | Decontamination process |
| US6599714B1 (en) | 1996-03-13 | 2003-07-29 | University Technologies International Inc. | Method of growing and analyzing a biofilm |
| FR2750326B1 (fr) | 1996-06-28 | 1998-07-31 | Oreal | Composition cosmetique et/ou dermatologique acide contenant un poly(acide 2-acrylamido 2-methylpropane sulfonique) reticule et neutralise a au moins 90 % |
| AU4062497A (en) | 1996-08-23 | 1998-03-06 | Isis Pharmaceuticals, Inc. | Normalization of combinatorial reactions |
| US6455031B1 (en) | 1997-06-18 | 2002-09-24 | David G Davies | Methods and compositions for controlling biofilm development |
| CA2301746C (en) | 1997-08-26 | 2011-02-15 | Board Of Regents, The University Of Texas System | Chelators in combination with biocides: treatment of microbially induced biofilm and corrosion |
| US20020037260A1 (en) | 1997-10-16 | 2002-03-28 | Budny John A. | Compositions for treating biofilm |
| US5906825A (en) | 1997-10-20 | 1999-05-25 | Magellan Companies, Inc. | Polymers containing antimicrobial agents and methods for making and using same |
| US6555055B1 (en) | 1998-07-29 | 2003-04-29 | Lynntech, Inc. | System for preventing and remediating biofilms in dental equipment |
| JP2002529545A (ja) | 1998-11-06 | 2002-09-10 | ユニベルシテ ドゥ モントリオール | バイオフィルムを除去するための改良型の殺菌性及び非殺菌性溶液 |
| US7326542B2 (en) | 1998-12-02 | 2008-02-05 | Princeton University | Compositions and methods for regulating bacterial pathogenesis |
| US6264926B1 (en) | 1999-02-12 | 2001-07-24 | Council Of Scientific And Industrial Research | Formulation useful as a natural herbal tooth powder |
| US6080323A (en) | 1999-02-17 | 2000-06-27 | Nalco Chemical Company | Method of removing biofilms from surfaces submerged in a fouled water system |
| US6369101B1 (en) | 1999-02-26 | 2002-04-09 | Regents Of The University Of Minnesota | Therapeutic method to treat herpes virus infection |
| US6395189B1 (en) | 1999-03-01 | 2002-05-28 | Polymer Ventures, Inc. | Method for the control of biofilms |
| US6498862B1 (en) | 1999-05-18 | 2002-12-24 | The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration | Evaluation of biofilms and the effects of biocides thereon |
| US20040033549A1 (en) | 1999-09-03 | 2004-02-19 | Greenberg E. Peter | Quorum sensing signaling in bacteria |
| US6482447B2 (en) | 1999-09-10 | 2002-11-19 | Glenn Braswell | Method and composition for the treatment of benign prostate hypertrophy (BPH) and prevention of prostate cancer |
| US6423219B1 (en) | 1999-09-14 | 2002-07-23 | James W. Chandler | System and method for controlling microorganisms and biofilms |
| WO2001070213A2 (en) | 2000-03-23 | 2001-09-27 | Influx, Inc. | Bactericidal antimicrobial methods and compositions for use in treating gram positive infections comprising an antibiotic potentiator having acyl hydrazide oxy amide or 8-hydroxy quinoline structure |
| US6596505B2 (en) | 2000-04-17 | 2003-07-22 | University Technologies International, Inc. | Apparatus and methods for testing effects of materials and surface coatings on the formation of biofilms |
| US6267897B1 (en) | 2000-05-04 | 2001-07-31 | Nalco Chemical Company | Method of inhibiting biofilm formation in commercial and industrial water systems |
| EP1409443A2 (de) * | 2000-12-20 | 2004-04-21 | Warner-Lambert Company | Nichthalogenierte naphtholverbindungen, diese enthaltende antimikrobielle zusammensetzungen und verfahren zu deren anwendung |
| FR2819410B1 (fr) | 2001-01-18 | 2003-02-21 | Oreal | Composition cosmetique irisee et ses utilisations |
| AU2002307448A1 (en) * | 2001-04-20 | 2002-11-05 | President And Fellows Of Harvard College | Methods and compositions for the modulation of biofilm formation |
| US6585961B1 (en) | 2001-11-30 | 2003-07-01 | Richard F. Stockel | Antimicrobial compositions |
| DE10204390A1 (de) | 2002-02-04 | 2003-08-14 | Bayer Cropscience Ag | Disubstituierte Thiazolylcarboxanilide |
| US6669929B1 (en) | 2002-12-30 | 2003-12-30 | Colgate Palmolive Company | Dentifrice containing functional film flakes |
| US20050137259A1 (en) | 2003-09-22 | 2005-06-23 | Use- Techno Corporation | Insulin secretion potentiator |
| US20060014285A1 (en) | 2004-07-14 | 2006-01-19 | Eldridge Gary R | Methods and compositions for inhibiting biofilms |
| WO2006010147A2 (en) | 2004-07-14 | 2006-01-26 | Eldridge Gary R | Control of biofilm formation |
| US20060264411A1 (en) | 2005-05-20 | 2006-11-23 | Eldridge Gary R | Control of biofilm formation |
| US7604978B2 (en) | 2004-07-14 | 2009-10-20 | Sequoia Sciences, Inc. | Inhibition of biofilm formation |
| CA2580078A1 (en) | 2004-09-14 | 2006-03-23 | Gary R. Eldridge | Compounds, compositions and methods for controlling biofilms and bacterial infections |
| WO2006102255A1 (en) | 2005-03-21 | 2006-09-28 | Sequoia Sciences, Inc. | Inhibition of biofilm formation |
| US20060228384A1 (en) | 2005-04-06 | 2006-10-12 | Sequoia Sciences, Inc. | Control of biofilm with a biofilm inhibitor |
| US20070014739A1 (en) | 2005-07-14 | 2007-01-18 | Eldridge Gary R | Compositions and methods for controlling biofilms and bacterial infections |
-
2005
- 2005-03-21 US US11/085,279 patent/US7604978B2/en not_active Expired - Fee Related
- 2005-07-14 WO PCT/US2005/025016 patent/WO2006019926A2/en not_active Ceased
- 2005-07-14 AT AT10002928T patent/ATE526957T1/de not_active IP Right Cessation
- 2005-07-14 DE DE602005020303T patent/DE602005020303D1/de not_active Expired - Lifetime
- 2005-07-14 DK DK10002928.9T patent/DK2213287T3/da active
- 2005-07-14 EP EP05791359A patent/EP1771558B1/de not_active Expired - Lifetime
- 2005-07-14 DK DK05791359.2T patent/DK1771558T3/da active
- 2005-07-14 AT AT05791359T patent/ATE462793T1/de not_active IP Right Cessation
- 2005-07-14 ES ES10002928T patent/ES2374152T3/es not_active Expired - Lifetime
- 2005-07-14 EP EP10002928A patent/EP2213287B1/de not_active Expired - Lifetime
- 2005-07-14 ES ES05791359T patent/ES2342411T3/es not_active Expired - Lifetime
- 2005-07-14 CA CA002573440A patent/CA2573440A1/en not_active Abandoned
-
2009
- 2009-10-08 US US12/576,022 patent/US20100041753A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2213287A1 (de) | 2010-08-04 |
| DK2213287T3 (da) | 2012-01-02 |
| WO2006019926A3 (en) | 2006-05-04 |
| US20060014290A1 (en) | 2006-01-19 |
| ES2374152T3 (es) | 2012-02-14 |
| EP1771558B1 (de) | 2010-03-31 |
| EP1771558A4 (de) | 2007-08-08 |
| US20100041753A1 (en) | 2010-02-18 |
| ES2342411T3 (es) | 2010-07-06 |
| EP2213287B1 (de) | 2011-10-05 |
| EP1771558A2 (de) | 2007-04-11 |
| CA2573440A1 (en) | 2006-02-23 |
| DE602005020303D1 (de) | 2010-05-12 |
| ATE462793T1 (de) | 2010-04-15 |
| WO2006019926A2 (en) | 2006-02-23 |
| US7604978B2 (en) | 2009-10-20 |
| DK1771558T3 (da) | 2010-07-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |