ATE527258T1 - Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung - Google Patents

Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung

Info

Publication number
ATE527258T1
ATE527258T1 AT05768664T AT05768664T ATE527258T1 AT E527258 T1 ATE527258 T1 AT E527258T1 AT 05768664 T AT05768664 T AT 05768664T AT 05768664 T AT05768664 T AT 05768664T AT E527258 T1 ATE527258 T1 AT E527258T1
Authority
AT
Austria
Prior art keywords
compound
pyrroloä2
cupyridine
production
proton pump
Prior art date
Application number
AT05768664T
Other languages
English (en)
Inventor
Atsushi Hasuoka
Yasuyoshi Arikawa
Original Assignee
Takeda Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35786398&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE527258(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical
Application granted granted Critical
Publication of ATE527258T1 publication Critical patent/ATE527258T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT05768664T 2004-07-28 2005-07-28 Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung ATE527258T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2004220788 2004-07-28
PCT/JP2005/014263 WO2006011670A1 (ja) 2004-07-28 2005-07-28 ピロロ［２，３－ｃ］ピリジン化合物、その製造方法および用途

Publications (1)

Publication Number Publication Date
ATE527258T1 true ATE527258T1 (de) 2011-10-15

Family

ID=35786398

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05768664T ATE527258T1 (de) 2004-07-28 2005-07-28 Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung

Country Status (6)

Country Link
US (2) US20070293532A1 (de)
EP (1) EP1787991B2 (de)
JP (1) JP4977465B2 (de)
KR (7) KR101764575B1 (de)
AT (1) ATE527258T1 (de)
WO (1) WO2006011670A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100958829B1 (ko) * 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법
US9101160B2 (en) 2005-11-23 2015-08-11 The Coca-Cola Company Condiments with high-potency sweetener
US8017168B2 (en) 2006-11-02 2011-09-13 The Coca-Cola Company High-potency sweetener composition with rubisco protein, rubiscolin, rubiscolin derivatives, ace inhibitory peptides, and combinations thereof, and compositions sweetened therewith
JP6211522B2 (ja) 2011-10-06 2017-10-11 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ ヘテロシクリルピリ（ミ）ジニルピラゾール
MX355016B (es) 2011-10-06 2018-04-02 Bayer Ip Gmbh Heterociclilpiri(mi)dinilpirazoles como fungicidas.
WO2014182033A1 (en) * 2013-05-08 2014-11-13 Yuhan Corporation Process for the preparation of pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof
WO2014189238A1 (en) * 2013-05-20 2014-11-27 Yuhan Corporation Process for the preparation of pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof
WO2016021742A1 (en) 2014-08-07 2016-02-11 Takeda Pharmaceutical Company Limited Heterocyclic compounds as ep4 receptor antagonists
EP3325490B1 (de) 2015-07-23 2019-12-18 Takeda Pharmaceutical Company Limited 1-substituierte 1,2,3,4-tetrahydro-1,7-naphthyridin-8-amin- derivate und ihre verwendung als ep4 rezeptor antagonisten
JP7353295B2 (ja) * 2018-04-10 2023-09-29 バイエル・アクチエンゲゼルシヤフト ２，６－ジアルキルフェニル酢酸の製造方法
KR102100725B1 (ko) * 2018-09-10 2020-04-14 윤민수 그래핀접촉패드부·사선줄기형 방열파이프·도트형 히트싱크를 통한 써드이펙트형 스마트폰용 케이스접촉방열장치 및 방법
CA3120866A1 (en) * 2018-11-30 2020-06-04 Nimbus Lakshmi, Inc. Tyk2 inhibitors and uses thereof
CN120752237A (zh) * 2022-12-22 2025-10-03 普罗泰克特治疗有限公司 吡咯并吡啶和吡咯并哒嗪类化合物及其作为pkr抑制剂的用途

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3555037A (en) * 1969-12-05 1971-01-12 American Cyanamid Co Certain 5,6,7,8-tetrahydro-beta-carbolines
JPS5936919B2 (ja) * 1978-10-14 1984-09-06 日本新薬株式会社 インド−ル誘導体
FR2687402B1 (fr) * 1992-02-14 1995-06-30 Lipha Nouveaux azaindoles, procedes de preparation et medicaments les contenant.
JP3465827B2 (ja) * 1993-02-24 2003-11-10 株式会社日清製粉グループ本社 アザインドール誘導体およびこれを有効成分とする抗潰瘍薬
GB2298199A (en) * 1995-02-21 1996-08-28 Merck Sharp & Dohme Synthesis of azaindoles
SE9700661D0 (sv) * 1997-02-25 1997-02-25 Astra Ab New compounds
EP1034167A1 (de) * 1997-09-25 2000-09-13 PHARMACIA & UPJOHN COMPANY Alpha-alkylsubstituierte pyrimidinether und -thioether als hemmer der viralen reversen transkriptase
SE9704404D0 (sv) * 1997-11-28 1997-11-28 Astra Ab New compounds
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
FR2804429B1 (fr) * 2000-01-31 2003-05-09 Adir Nouveaux derives de 4-sulfonamides piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2001294587A (ja) * 2000-02-10 2001-10-23 Sankyo Co Ltd ピロロピリダジン化合物
ES2286094T3 (es) * 2000-02-10 2007-12-01 Sankyo Company, Limited Compuesto de pirrolopiridacina.
WO2001058869A2 (en) * 2000-02-11 2001-08-16 Bristol-Myers Squibb Company Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases
EP1209158A1 (de) * 2000-11-18 2002-05-29 Aventis Pharma Deutschland GmbH Substitutierte beta-Carboline
US6825201B2 (en) * 2001-04-25 2004-11-30 Bristol-Myers Squibb Company Indole, azaindole and related heterocyclic amidopiperazine derivatives
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
CA2478156C (en) * 2002-03-26 2011-02-15 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
AU2003288071A1 (en) * 2002-11-19 2004-06-15 Altana Pharma Ag 8-substituted imidazopyridines
US7608627B2 (en) 2004-04-05 2009-10-27 Takeda Pharmaceutical Company Limited 6-azaindole compound
KR20070034049A (ko) * 2004-06-09 2007-03-27 글락소 그룹 리미티드 피롤로피리딘 유도체
KR100958829B1 (ko) † 2004-09-03 2010-05-25 주식회사유한양행 피롤로[2,3-ｃ]피리딘 유도체 및 그의 제조방법

Also Published As

Publication number Publication date
KR20150006071A (ko) 2015-01-15
US20070293532A1 (en) 2007-12-20
KR20070053231A (ko) 2007-05-23
US20180148446A1 (en) 2018-05-31
KR20220084426A (ko) 2022-06-21
KR20180118255A (ko) 2018-10-30
EP1787991B1 (de) 2011-10-05
EP1787991A4 (de) 2008-10-01
EP1787991B2 (de) 2020-06-24
KR20120132582A (ko) 2012-12-05
WO2006011670A1 (ja) 2006-02-02
EP1787991A1 (de) 2007-05-23
KR20170091178A (ko) 2017-08-08
KR101913531B1 (ko) 2018-10-30
JP4977465B2 (ja) 2012-07-18
KR20200105967A (ko) 2020-09-09
KR102152809B1 (ko) 2020-09-07
KR101764575B1 (ko) 2017-08-03
JPWO2006011670A1 (ja) 2008-05-01

Similar Documents

Publication Publication Date Title
ATE527258T1 (de) Pyrroloä2,3-cüpyridinverbindung, verfahren zu deren herstellung und anwendung
WO2007092641A3 (en) Method for substituted 1h-imidazo[4,5-c]pyridines
WO2008082487A3 (en) Novel jnk inhibitors
MXPA05007516A (es) Derivados de hexahidropirazino[1,2-a]pirimidina -4, 7-diona sustituidos, metodo para producirlos y su uso como medicamentos.
WO2005082907A3 (de) Pyrazolopyrimidine zur bekämpfung unerwünschter mikroorganismen
DE60311599D1 (de) Verfahren zur herstellung von duloxetin und deren verwendeten zwischenprodukten
ATE533765T1 (de) Pyrroloä2,3-cüpyridinderivate und verfahren für deren herstellung
DE602004018494D1 (de) Fluvastatin-natrium in der kristallform xiv, verfahren zu deren herstellung, diese enthaltende zusammensetzungen und enstprechende anwendungsverfahren
ATE468907T1 (de) Keramische nanofiltrationsmembran für die verwendung in organischen lösungsmitteln und verfahren zu deren herstellung
WO2009018065A3 (en) Novel glucokinase activators and methods of using same
DE602004005888D1 (de) Herstellung von selbstorganisierten monoschichten
DE502004002037D1 (de) Umgelagerte pentanole, ein verfahren zu ihrer herstellung und ihre verwendung als entz ndungshemmer
ATE506352T1 (de) Verfahren zur herstellung von optional 2- substituierten 1,6-dihydro-6-oxo-4- pyrimidincarboxylsäuren
WO2006066950A3 (de) Tricyclische aminoalkohole, verfahren zu ihrer herstellung und ihre verwendung als entzündungshemmer
EP1405917A3 (de) Verfahren zur Herstellung von 3-Heteroaryl-3-hydroxy-propansäurederivaten durch enantionselektive mikrobielle Reduktion
ATE415404T1 (de) Lösungsmittelfreies verfahren zur herstellung von diketopyrrolopyrrol-derivaten
WO2006061215A3 (de) 2-alkyl-cycloalk(en)yl-carboxamide
DE60313157D1 (de) Ein verfahren zur herstellung von clopidogrel
ATE550313T1 (de) Verfahren zur herstellung von xylitol
ATE526312T1 (de) Verfahren zur herstellung von reinen 4- pyrrolidinophenylbenzyletherderivaten als maob- inhibitoren
ATE444323T1 (de) Neuartige epoxidverbindungen und verfahren zu ihrer herstellung
DE60014936D1 (de) Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel
ATE489385T1 (de) Verfahren zur herstellung von imidazopyridinen
DE602006014001D1 (de) Herstellung von 2-aminothiazol-5-carbonsäurederivaten
ATE356116T1 (de) Neues verfahren zur herstellung von 2- aminomethylpyridinderivaten

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties