ATE527339T1 - Anthrax-kohlenhydrate sowie synthese und verwendungen davon - Google Patents

Anthrax-kohlenhydrate sowie synthese und verwendungen davon

Info

Publication number
ATE527339T1
ATE527339T1 AT07874407T AT07874407T ATE527339T1 AT E527339 T1 ATE527339 T1 AT E527339T1 AT 07874407 T AT07874407 T AT 07874407T AT 07874407 T AT07874407 T AT 07874407T AT E527339 T1 ATE527339 T1 AT E527339T1
Authority
AT
Austria
Prior art keywords
synthesis
anthrax
carbohydrates
oligosaccharides
present
Prior art date
Application number
AT07874407T
Other languages
English (en)
Inventor
Russell Carlson
Geert-Jan Boons
Therese Buskas
Biswa Choudhury
Elmar Kannenberg
Christine Leoff
Alok Mehta
Conrad Quinn
Elke Saile
Patricia Wilkins
Jana Rauvolfova
Original Assignee
Univ Georgia
Us Of America As Represented By The Secretary Of The Dept Of Health And Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Georgia, Us Of America As Represented By The Secretary Of The Dept Of Health And Human Services filed Critical Univ Georgia
Application granted granted Critical
Publication of ATE527339T1 publication Critical patent/ATE527339T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/32—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Bacillus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1278—Bacillus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/32—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Bacillus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT07874407T 2006-06-30 2007-06-29 Anthrax-kohlenhydrate sowie synthese und verwendungen davon ATE527339T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81792906P 2006-06-30 2006-06-30
US93393707P 2007-06-08 2007-06-08
PCT/US2007/015196 WO2008115198A2 (en) 2006-06-30 2007-06-29 Anthrax carbohydrates,synthesis and uses thereof

Publications (1)

Publication Number Publication Date
ATE527339T1 true ATE527339T1 (de) 2011-10-15

Family

ID=39766625

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07874407T ATE527339T1 (de) 2006-06-30 2007-06-29 Anthrax-kohlenhydrate sowie synthese und verwendungen davon

Country Status (6)

Country Link
US (1) US9310366B2 (de)
EP (2) EP2264143A3 (de)
AT (1) ATE527339T1 (de)
AU (1) AU2007349310B2 (de)
CA (1) CA2656606A1 (de)
WO (1) WO2008115198A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8343495B2 (en) * 2009-01-10 2013-01-01 Auburn University Equine antibodies against Bacillus anthracis for passive immunization and treatment
CN118662649A (zh) 2016-12-30 2024-09-20 Vaxcyte公司 具有非天然氨基酸的多肽-抗原缀合物
US11951165B2 (en) 2016-12-30 2024-04-09 Vaxcyte, Inc. Conjugated vaccine carrier proteins
WO2020051566A1 (en) * 2018-09-07 2020-03-12 Immunotope, Inc. Vaccines with enhanced immune response and methods for their preparation

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5677274A (en) 1993-02-12 1997-10-14 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services Anthrax toxin fusion proteins and related methods
US5591631A (en) 1993-02-12 1997-01-07 The United States Of America As Represented By The Department Of Health And Human Services Anthrax toxin fusion proteins, nucleic acid encoding same
US6685949B1 (en) 1998-01-13 2004-02-03 The United States Of America As Represented By The Department Of Health & Human Services Lipooligosaccharide based vaccine for prevention of moraxella (branhamella)catarrhalis infections in humans
US6592872B1 (en) 1996-09-17 2003-07-15 The United States Of America As Represented By The Department Of Health And Human Services Targeting antigens to the MHC class I processing pathway with an anthrax toxin fusion protein
US5952454A (en) 1997-12-12 1999-09-14 The United States Of America As Represented By The Department Of Health And Human Services Linking compounds useful for coupling carbohydrates to amine-containing carriers
WO1999055715A2 (en) * 1998-04-28 1999-11-04 Galenica Pharmaceuticals, Inc. Polysaccharide-antigen conjugates
US6913756B1 (en) 1998-04-29 2005-07-05 The Uab Research Foundation Monoclonal antibodies specific for anthrax and peptides derived from the antibodies thereof
DE69935344D1 (de) 1998-10-06 2007-04-12 Massachusetts Inst Technology Synthese von Oligosacchariden, Reagenzien und Verfahren
CA2363499C (en) 1999-03-05 2010-06-01 Massachusetts Institute Of Technology Linkers for synthesis of oligosaccharides on solid supports
WO2001038337A2 (en) 1999-11-24 2001-05-31 Massachusetts Institute Of Technology Protecting groups useful in the synthesis of polysaccharides, natural products, and combinatorial libraries
CA2396696A1 (en) 2000-01-06 2001-07-12 Biosite Diagnostics, Inc. Assays for detection of bacillus anthracis
EP1280828B1 (de) * 2000-04-28 2006-09-13 Tetracore, Inc. Anthrax-spezifisches antigen, impfstoffe die das antigen enthalten, anthrax-spezifische antikörper, und deren verwendungen
CA2420183C (en) 2000-08-18 2009-11-24 Massachusetts Institute Of Technology Apparatus and methods for the automated synthesis of oligosaccharides
CA2435637A1 (en) 2001-01-23 2002-08-01 Massachusetts Institute Of Technology Solid- and solution -phase synthesis of heparin and other glycosaminoglycans
US7786094B2 (en) 2001-10-09 2010-08-31 Biopolymer Engineering, Inc. Use of beta-glucans against biological warfare weapons and pathogens including anthrax
UA80809C2 (en) 2001-11-05 2007-11-12 Process for preparation of protective antigen protein of anthracis with e.coli
AU2002354047B2 (en) 2001-11-05 2007-11-22 Board Of Regents, The University Of Texas System Recombinant antibodies for the detection and neutralization of anthrax toxin
US20040033546A1 (en) * 2002-04-10 2004-02-19 The Trustees Of Columbia University In The City Of New York Novel microarrays and methods of use thereof
US6916474B2 (en) 2002-07-15 2005-07-12 Board Of Regents, The University Of Texas System Antibodies with increased affinities for anthrax antigens
WO2005007804A2 (en) 2003-04-10 2005-01-27 President And Fellows Of Harvard College Anthrax conjugate vaccine and antibodies
US8673285B2 (en) 2003-06-18 2014-03-18 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Sphingoid polyalkylamine conjugates for vaccination
GB0317376D0 (en) * 2003-07-25 2003-08-27 Secr Defence Immunogenic protein and uses thereof
CA2532881A1 (en) 2003-07-30 2005-06-02 Merck & Co., Inc. Anthrax vaccine
US20050221337A1 (en) 2003-10-02 2005-10-06 Massachusetts Institute Of Technology Microarrays and microspheres comprising oligosaccharides, complex carbohydrates or glycoproteins
WO2005081749A2 (en) 2004-01-23 2005-09-09 Avanir Pharmaceuticals, Inc. Neutralizing human antibodies to anthraxtoxin
US20050107295A1 (en) 2003-11-19 2005-05-19 Naveen Arora Novel protein capable of inhibiting anthrax toxin activity
CA2549914C (en) 2003-12-05 2012-05-29 Council Of Scientific And Industrial Research A novel protein capable of inhibiting anthrax toxin activity
WO2006093524A2 (en) 2004-07-16 2006-09-08 The General Hospital Corporation Antigen-carbohydrate conjugates
US8617819B2 (en) 2004-09-17 2013-12-31 Massachusetts Institute Of Technology Polymers for analyte detection
WO2006055925A2 (en) 2004-11-19 2006-05-26 Swiss Federal Institute Of Technology Microarrays for analyte detection
WO2006068758A2 (en) 2004-11-19 2006-06-29 The Scripps Research Institute Detection, prevention and treatment of breast cancer
WO2007099392A2 (en) 2005-09-27 2007-09-07 Swiss Federal Institute Of Technology Convergent synthesis of carbohydrate building blocks
EP1934244A2 (de) 2005-10-06 2008-06-25 Emthrax LLC Verfahren und zusammensetzungen in verbindung mit milzbrandsporen-glycoproteinen als impfstoffe
EP2012821A2 (de) 2006-04-28 2009-01-14 ETH Zürich Antikörper zum nachweis von bacillus anthracis und impfstoff gegen b. anthracis-infektionen
US8420607B2 (en) 2006-06-30 2013-04-16 University Of Georgia Research Foundation, Inc. Anthrax carbohydrates, synthesis and uses thereof
CN104962586A (zh) 2006-07-21 2015-10-07 希乐克公司 生物质转化系统
WO2008042261A2 (en) 2006-09-28 2008-04-10 Elusys Therapeutics, Inc. Anti-anthrax antibody, formulations thereof, and methods of use

Also Published As

Publication number Publication date
EP2044194A2 (de) 2009-04-08
EP2264143A3 (de) 2012-03-07
EP2264143A2 (de) 2010-12-22
WO2008115198A2 (en) 2008-09-25
US20130260402A1 (en) 2013-10-03
WO2008115198A9 (en) 2008-12-24
AU2007349310B2 (en) 2013-03-14
EP2044194A4 (de) 2009-10-28
WO2008115198A3 (en) 2008-11-13
US9310366B2 (en) 2016-04-12
EP2044194B1 (de) 2011-10-05
CA2656606A1 (en) 2008-09-25
AU2007349310A1 (en) 2008-09-25

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties