ATE527340T1 - Hemmung der stammzelldifferenzierung, verbesserung der proliferation und selektive induktion von apoptose durch wnt-faktoren - Google Patents

Hemmung der stammzelldifferenzierung, verbesserung der proliferation und selektive induktion von apoptose durch wnt-faktoren

Info

Publication number
ATE527340T1
ATE527340T1 AT04808705T AT04808705T ATE527340T1 AT E527340 T1 ATE527340 T1 AT E527340T1 AT 04808705 T AT04808705 T AT 04808705T AT 04808705 T AT04808705 T AT 04808705T AT E527340 T1 ATE527340 T1 AT E527340T1
Authority
AT
Austria
Prior art keywords
population
proliferation
differentiation
apoptosis
cells
Prior art date
Application number
AT04808705T
Other languages
English (en)
Inventor
Menno Kielman
Original Assignee
Deltacell B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Deltacell B V filed Critical Deltacell B V
Application granted granted Critical
Publication of ATE527340T1 publication Critical patent/ATE527340T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0603—Embryonic cells ; Embryoid bodies
    • C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0688—Cells from the lungs or the respiratory tract
    • C12N5/0689—Stem cells; Progenitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/40—Regulators of development
    • C12N2501/415—Wnt; Frizzeled

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • General Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT04808705T 2003-11-11 2004-11-11 Hemmung der stammzelldifferenzierung, verbesserung der proliferation und selektive induktion von apoptose durch wnt-faktoren ATE527340T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US51940303P 2003-11-11 2003-11-11
EP03078549A EP1548100A1 (de) 2003-11-11 2003-11-11 Inhibierung der differenzierung von stammzellen, förderung des wachstums und selektive induktion von apoptose durch wnt faktoren
PCT/NL2004/000789 WO2005052141A1 (en) 2003-11-11 2004-11-11 Inhibition of stem cell differentiation, enhancement of proliferation and selective induction of apoptosis by wnt factors

Publications (1)

Publication Number Publication Date
ATE527340T1 true ATE527340T1 (de) 2011-10-15

Family

ID=34530748

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04808705T ATE527340T1 (de) 2003-11-11 2004-11-11 Hemmung der stammzelldifferenzierung, verbesserung der proliferation und selektive induktion von apoptose durch wnt-faktoren

Country Status (7)

Country Link
US (2) US20060270035A1 (de)
EP (2) EP1548100A1 (de)
AT (1) ATE527340T1 (de)
CA (1) CA2545520A1 (de)
DK (1) DK1689856T3 (de)
ES (1) ES2374729T3 (de)
WO (1) WO2005052141A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2308877B1 (es) * 2005-11-28 2009-10-26 Consejo Superior Investig. Cientificas Empleo de nuemocitos tipo ii en el tratamiento de enfermedades pulmonares que cursan con fibrosis pulmonar.
KR102045130B1 (ko) * 2014-12-05 2019-11-14 메리디젠 바이오테크 컴퍼니 리미티드 중간엽 줄기세포를 구별하는 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0736034A4 (de) 1993-12-22 1999-02-03 Merck & Co Inc Den wnt-x wachstumsfaktor kodierende dns
EP1235485A4 (de) * 1999-12-07 2005-08-31 Los Angeles Childrens Hospital Lungenstammzellen und lungenregeneration
EP1222933A1 (de) * 2001-01-15 2002-07-17 Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum Bildung und/oder Reduktion von neuem Lungengewebe in einer erkranketen Lunge, durch Modulierung des Wnt-Signalwegs
US9414708B2 (en) 2014-03-14 2016-08-16 Ming-Tung Liu Brewing container with double-layer filtering structure

Also Published As

Publication number Publication date
DK1689856T3 (da) 2012-01-30
EP1548100A1 (de) 2005-06-29
ES2374729T3 (es) 2012-02-21
EP1689856B1 (de) 2011-10-05
EP1689856A1 (de) 2006-08-16
WO2005052141A1 (en) 2005-06-09
US20060270035A1 (en) 2006-11-30
CA2545520A1 (en) 2005-06-09
US20100203634A1 (en) 2010-08-12

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