ATE529097T1 - Pharmazeutische zubereitung in form einer paste mit einem säurelabilen wirkstoff - Google Patents

Pharmazeutische zubereitung in form einer paste mit einem säurelabilen wirkstoff

Info

Publication number
ATE529097T1
ATE529097T1 AT01991781T AT01991781T ATE529097T1 AT E529097 T1 ATE529097 T1 AT E529097T1 AT 01991781 T AT01991781 T AT 01991781T AT 01991781 T AT01991781 T AT 01991781T AT E529097 T1 ATE529097 T1 AT E529097T1
Authority
AT
Austria
Prior art keywords
active ingredient
pharmaceutical preparation
acid
paste
paste containing
Prior art date
Application number
AT01991781T
Other languages
English (en)
Inventor
Rango Dietrich
Rudolf Linder
Original Assignee
Nycomed Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nycomed Gmbh filed Critical Nycomed Gmbh
Application granted granted Critical
Publication of ATE529097T1 publication Critical patent/ATE529097T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT01991781T 2000-12-07 2001-12-05 Pharmazeutische zubereitung in form einer paste mit einem säurelabilen wirkstoff ATE529097T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00126828 2000-12-07
PCT/EP2001/014253 WO2002045686A2 (en) 2000-12-07 2001-12-05 Pharmaceutical paste comprising an acid-labile active ingredient

Publications (1)

Publication Number Publication Date
ATE529097T1 true ATE529097T1 (de) 2011-11-15

Family

ID=8170595

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01991781T ATE529097T1 (de) 2000-12-07 2001-12-05 Pharmazeutische zubereitung in form einer paste mit einem säurelabilen wirkstoff

Country Status (15)

Country Link
US (1) US7988999B2 (de)
EP (1) EP1341524B1 (de)
JP (1) JP4241041B2 (de)
KR (1) KR20030059314A (de)
CN (1) CN100536844C (de)
AT (1) ATE529097T1 (de)
AU (1) AU2002231654A1 (de)
BR (1) BR0115985A (de)
CA (1) CA2430816C (de)
CY (1) CY1112510T1 (de)
DK (1) DK1341524T3 (de)
ES (1) ES2375269T3 (de)
PT (1) PT1341524E (de)
SI (1) SI1341524T1 (de)
WO (1) WO2002045686A2 (de)

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MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EA009985B1 (ru) 2003-03-10 2008-04-28 Никомед Гмбх Новый способ получения рофлумиласта
JP4109286B2 (ja) * 2003-05-02 2008-07-02 順也 藤森 親水性ブレンドゲル
WO2004112756A1 (en) * 2003-06-26 2004-12-29 Isa Odidi Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient
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EP1711179A2 (de) * 2004-01-28 2006-10-18 Altana Pharma AG Calcium-, kalium-, zink-, lithium- und aluminiumsalze von pantoprazol und (s)-pantoprazol
US8394409B2 (en) * 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
JP2006176461A (ja) * 2004-12-24 2006-07-06 Dai Ichi Seiyaku Co Ltd 粒状物
ES2421916T3 (es) * 2005-03-16 2013-09-06 Nycomed Gmbh Forma farmacéutica de sabor enmascarado que contiene roflumilast
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
CN104825397A (zh) * 2006-04-03 2015-08-12 伊萨·奥迪迪 含有机溶胶涂层的受控释放递送物件
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US10960077B2 (en) * 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
EP2079477B1 (de) 2006-10-10 2017-07-26 Wisconsin Alumni Research Foundation Intramammäre zitzen-abdichtungsformulierung und verfahren zu ihrer verwendung zur verringerung oder eliminierung von visuellen defekten in reifem käse
CN105944095B (zh) * 2008-03-05 2021-04-02 赛诺菲巴斯德有限公司 一种使含佐剂的疫苗组合物稳定的方法
WO2009136398A2 (en) 2008-05-06 2009-11-12 Dexcel Ltd Stable benzimidazole formulation
KR20120005497A (ko) * 2009-04-08 2012-01-16 위스콘신 얼럼나이 리서어치 화운데이션 유방내 유두 밀봉 제제 및 이를 사용하여 숙성된 치즈에서 시각적 결함을 감소 또는 제거시키는 방법
EP2526931B1 (de) * 2011-05-23 2014-12-17 Deva Holding Anonim Sirketi Nasse Granulationsmethoden für Cetylmyristat und/oder Cetylpalmitat
FR2994390B1 (fr) 2012-08-10 2014-08-15 Adocia Procede d'abaissement de la viscosite de solutions de proteines a concentration elevee
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
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WO2021016134A1 (en) * 2019-07-19 2021-01-28 Spi Pharma, Inc. Preparation of lipophilic active ingredients

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Also Published As

Publication number Publication date
CN1479611A (zh) 2004-03-03
JP2004514733A (ja) 2004-05-20
US7988999B2 (en) 2011-08-02
CY1112510T1 (el) 2015-12-09
EP1341524A2 (de) 2003-09-10
WO2002045686A3 (en) 2002-12-12
KR20030059314A (ko) 2003-07-07
PT1341524E (pt) 2011-12-30
BR0115985A (pt) 2003-12-23
CA2430816A1 (en) 2002-06-13
EP1341524B1 (de) 2011-10-19
AU2002231654A1 (en) 2002-06-18
CN100536844C (zh) 2009-09-09
ES2375269T3 (es) 2012-02-28
DK1341524T3 (da) 2012-01-16
SI1341524T1 (sl) 2012-02-29
CA2430816C (en) 2012-05-15
US20040101558A1 (en) 2004-05-27
WO2002045686A2 (en) 2002-06-13
JP4241041B2 (ja) 2009-03-18

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