ATE529746T1 - Zusammensetzung und verfahren zum nachweis von analyten über eine polymerisierungsbasierte signalverstärkung - Google Patents

Zusammensetzung und verfahren zum nachweis von analyten über eine polymerisierungsbasierte signalverstärkung

Info

Publication number
ATE529746T1
ATE529746T1 AT08780435T AT08780435T ATE529746T1 AT E529746 T1 ATE529746 T1 AT E529746T1 AT 08780435 T AT08780435 T AT 08780435T AT 08780435 T AT08780435 T AT 08780435T AT E529746 T1 ATE529746 T1 AT E529746T1
Authority
AT
Austria
Prior art keywords
composition
signal amplification
based signal
detecting analytes
via polymerization
Prior art date
Application number
AT08780435T
Other languages
English (en)
Inventor
Su Lu
John Yupeng Gui
Bahram Moasser
Wei Cai
Zhixin Zheng
John R Nelson
Original Assignee
Gen Electric
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Electric filed Critical Gen Electric
Application granted granted Critical
Publication of ATE529746T1 publication Critical patent/ATE529746T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT08780435T 2007-02-28 2008-02-20 Zusammensetzung und verfahren zum nachweis von analyten über eine polymerisierungsbasierte signalverstärkung ATE529746T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/680,597 US8741813B2 (en) 2005-12-15 2007-02-28 Composition, device and associated method
PCT/US2008/054357 WO2008127779A2 (en) 2007-02-28 2008-02-20 Composition and method for the detection of analytes using polymerization based signal amplification

Publications (1)

Publication Number Publication Date
ATE529746T1 true ATE529746T1 (de) 2011-11-15

Family

ID=39744062

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08780435T ATE529746T1 (de) 2007-02-28 2008-02-20 Zusammensetzung und verfahren zum nachweis von analyten über eine polymerisierungsbasierte signalverstärkung

Country Status (4)

Country Link
US (1) US8741813B2 (de)
EP (1) EP2122351B1 (de)
AT (1) ATE529746T1 (de)
WO (1) WO2008127779A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5775004B2 (ja) * 2009-03-03 2015-09-09 アクセス メディカル システムズ,リミティド 高感度蛍光分析のための検出システム及び方法
GB201003594D0 (en) * 2010-03-04 2010-04-21 Eluceda Ltd Method for detecting the presence of specific micro-organisms and device for the same
KR20120128440A (ko) * 2011-05-17 2012-11-27 삼성전자주식회사 표적 물질 검출용 키트 및 이를 이용한 표적 물질 검출 방법
US9033159B1 (en) * 2011-06-07 2015-05-19 Clemson University Membrane surface modification
US20250230272A1 (en) * 2022-04-13 2025-07-17 Inkbit, LLC Materials for free-radical activation of a latent catalyst for ring-opening metathesis polymerization (romp) and uses thereof

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4511478A (en) * 1983-11-10 1985-04-16 Genetic Systems Corporation Polymerizable compounds and methods for preparing synthetic polymers that integrally contain polypeptides
US5035997A (en) 1989-02-17 1991-07-30 Gerald Oster Redox polymerization diagnostic test composition and method for immunoassay and nuclei acid assay
US5176966A (en) * 1990-11-19 1993-01-05 Ballard Power Systems Inc. Fuel cell membrane electrode and seal assembly
US5424413A (en) * 1992-01-22 1995-06-13 Gen-Probe Incorporated Branched nucleic acid probes
FR2710075B1 (fr) 1993-09-15 1995-10-27 Bio Merieux Réactif et procédé pour la détection d'une séquence nucléotidique avec amplification de signal.
US7125938B2 (en) * 1997-03-11 2006-10-24 Carnegie Mellon University Atom or group transfer radical polymerization
WO2000046257A1 (en) 1999-02-05 2000-08-10 Materia, Inc. Metathesis-active adhesion agents and methods for enhancing polymer adhesion to surfaces
US6692914B1 (en) * 1999-07-02 2004-02-17 Symyx Technologies, Inc. Polymer brushes for immobilizing molecules to a surface or substrate, where the polymers have water-soluble or water-dispersible segments and probes bonded thereto
US20030113740A1 (en) 2001-04-26 2003-06-19 Mirkin Chad A. Oligonucleotide-modified ROMP polymers and co-polymers
AU2002336613A1 (en) 2001-09-18 2003-04-01 U.S. Genomics, Inc. Differential tagging of polymers for high resolution linear analysis
AU2002357178A1 (en) * 2001-12-14 2003-06-30 Cygene, Inc. Diagnostic assays for bcwa
DE10210224A1 (de) 2002-03-08 2003-09-25 Infineon Technologies Ag Analysesystem zum Nachweis von Analyten
US6992156B2 (en) * 2002-12-31 2006-01-31 The Goodyear Tire & Rubber Company Controlled polymerization
ATE464399T1 (de) 2003-09-09 2010-04-15 Univ Colorado Regents Verwendung der photopolymerisierung zur amplifikation und zum nachweis eines molekularen erkennungsereignisses
US20050196790A1 (en) 2004-02-05 2005-09-08 U.S. Genomics, Inc. Methods for detection and quantitation of minimum length polymers
JP2007529758A (ja) 2004-03-19 2007-10-25 ユー.エス. ジェノミクス, インコーポレイテッド 単一分子の検出のための組成物および方法

Also Published As

Publication number Publication date
WO2008127779A2 (en) 2008-10-23
US20140072956A1 (en) 2014-03-13
EP2122351A2 (de) 2009-11-25
US8741813B2 (en) 2014-06-03
WO2008127779A3 (en) 2008-12-18
EP2122351B1 (de) 2011-10-19

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