ATE530632T1 - Verfahren zur herstellung eines biopolymers (z.b. polypeptids) in einem kontinuierlichen fermentationsverfahren - Google Patents

Verfahren zur herstellung eines biopolymers (z.b. polypeptids) in einem kontinuierlichen fermentationsverfahren

Info

Publication number
ATE530632T1
ATE530632T1 AT08774069T AT08774069T ATE530632T1 AT E530632 T1 ATE530632 T1 AT E530632T1 AT 08774069 T AT08774069 T AT 08774069T AT 08774069 T AT08774069 T AT 08774069T AT E530632 T1 ATE530632 T1 AT E530632T1
Authority
AT
Austria
Prior art keywords
biopolymer
polypeptide
producing
fermentation process
continuous fermentation
Prior art date
Application number
AT08774069T
Other languages
English (en)
Inventor
Mads Laustsen
Original Assignee
Cmc Biolog As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38229532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE530632(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cmc Biolog As filed Critical Cmc Biolog As
Application granted granted Critical
Publication of ATE530632T1 publication Critical patent/ATE530632T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT08774069T 2007-06-13 2008-06-11 Verfahren zur herstellung eines biopolymers (z.b. polypeptids) in einem kontinuierlichen fermentationsverfahren ATE530632T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07110227A EP2014760A1 (de) 2007-06-13 2007-06-13 Methode zur Produktion eines Biopolymers (z.B. eines Polypeptides) in einem kontinuierlichen Fermentationsprozess
PCT/EP2008/057332 WO2008152075A1 (en) 2007-06-13 2008-06-11 A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process

Publications (1)

Publication Number Publication Date
ATE530632T1 true ATE530632T1 (de) 2011-11-15

Family

ID=38229532

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08774069T ATE530632T1 (de) 2007-06-13 2008-06-11 Verfahren zur herstellung eines biopolymers (z.b. polypeptids) in einem kontinuierlichen fermentationsverfahren

Country Status (6)

Country Link
US (1) US8679778B2 (de)
EP (2) EP2014760A1 (de)
AT (1) ATE530632T1 (de)
DK (1) DK2171034T3 (de)
ES (1) ES2375780T3 (de)
WO (1) WO2008152075A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101685246B1 (ko) 2006-07-14 2016-12-09 디피엑스 홀딩스 비.브이. 개선된 세포 배양 방법
EP2957628A1 (de) * 2010-10-05 2015-12-23 Novo Nordisk Health Care AG Verfahren zur proteinherstellung
JP6375112B2 (ja) * 2010-12-23 2018-08-15 ジェノヴァ バイオファーマシューティカルズ リミテッド テネクテプラーゼの医薬組成物
TWI815599B (zh) 2011-04-22 2023-09-11 美商惠氏有限責任公司 與難養芽胞梭菌（Ｃｌｏｓｔｒｉｄｉｕｍ ｄｉｆｆｉｃｉｌｅ）之突變毒素有關之組成物及彼之方法
BR112014009146A8 (pt) 2011-10-18 2017-06-20 Coherus Biosciences Inc formulações de etanercepte estabilizadas com aminoácidos
US10485869B2 (en) 2011-10-18 2019-11-26 Coherus Biosciences, Inc. Etanercept formulations stabilized with meglumine
JP5975236B2 (ja) * 2011-11-02 2016-08-23 ユニバーシティ プトゥラ マレーシア 生体高分子の製造方法
EP2682168A1 (de) 2012-07-02 2014-01-08 Millipore Corporation Reinigung biologischer Moleküle
HK1209343A1 (en) 2012-07-09 2016-04-01 Coherus Biosciences, Inc. Etanercept formulations exhibiting marked reduction in sub-visible particles
SI2895188T1 (en) 2012-09-11 2018-05-31 Coherus Biosciences, Inc. CORRECTED QUALITY ETHANERCEPT WITH HIGH QUALITY AND EXCELLENT EXPERIENCE
BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
ES2842350T3 (es) 2013-03-19 2021-07-13 Cmc Biologics As Un procedimiento para la producción de un producto (por ejemplo, polipéptido) en un proceso de fermentación de cultivo celular continuo
SG10201802023RA (en) * 2013-03-26 2018-05-30 Coherus Biosciences Inc Protein production method
US11286292B2 (en) 2014-02-07 2022-03-29 Cmc Biologics A/S Bioreactor arrangement and continuous process for producing and capturing a biopolymer
NZ724826A (en) * 2014-04-16 2022-07-29 Cmc Biologics As A high cell density fill and draw fermentation process
AU2015269365A1 (en) 2014-06-04 2016-12-15 Amgen Inc. Methods for harvesting mammalian cell cultures
CN106414719B (zh) * 2014-06-13 2020-02-14 杰特有限公司 生物反应器中重组von Willebrand因子的改进生产
JP6530171B2 (ja) * 2014-09-09 2019-06-12 旭化成メディカル株式会社 培養産生物の回収方法
EP3303557B1 (de) 2015-05-29 2021-05-05 Glycotope GmbH Kultivierungsverfahren in kleinem massstab für suspensionszellen
US11339775B2 (en) * 2016-07-25 2022-05-24 Repligen Corporation Alternating tangential flow rapid harvesting
KR20220129006A (ko) * 2020-01-15 2022-09-22 우시 바이올로직스 아일랜드 리미티드 배양 세포로부터 생산된 생체 물질을 연속적으로 수확하기 위한 장치 및 방법
WO2021255690A2 (en) 2020-06-19 2021-12-23 Pfizer Inc. Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof
EP4228794A1 (de) 2020-10-15 2023-08-23 AGC Biologics, Inc. Kontinuierliche kultur mit hoher zelldichte und tangentialer strömungsfiltration mit zwei behältern

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US5286646A (en) * 1985-11-25 1994-02-15 Boehringer Mannheim Gmbh Method for mammalian cell culture
US4709442A (en) * 1986-10-21 1987-12-01 Advance Machine Company Portable extractor
DE3641824A1 (de) * 1986-12-06 1988-06-16 Bayer Ag Verfahren und vorrichtung zur kultivierung immobilisierter oder adhaerierter saeugerzellen sowie dessen verwendung bei der herstellung von proteinen
US4806484A (en) * 1987-08-07 1989-02-21 Igb Products, Ltd. Perfusion airlift bioreactor
US5342781A (en) * 1993-07-15 1994-08-30 Su Wei Wen W External-loop perfusion air-lift bioreactor
US6544424B1 (en) * 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
AU2002252704A1 (en) * 2001-04-20 2002-11-05 E.I. Du Pont De Nemours And Company A product removal process for use in a biofermentation system
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
CA2557046A1 (en) 2004-03-05 2005-10-13 John Crowley Process for cell culturing by continuous perfusion and alternating tangential flow

Also Published As

Publication number Publication date
ES2375780T3 (es) 2012-03-06
US8679778B2 (en) 2014-03-25
EP2171034A1 (de) 2010-04-07
EP2171034B1 (de) 2011-10-26
EP2014760A1 (de) 2009-01-14
WO2008152075A1 (en) 2008-12-18
DK2171034T3 (da) 2012-02-13
US20100184149A1 (en) 2010-07-22

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