DK2171034T3 - Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces - Google Patents

Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces

Info

Publication number
DK2171034T3
DK2171034T3 DK08774069.2T DK08774069T DK2171034T3 DK 2171034 T3 DK2171034 T3 DK 2171034T3 DK 08774069 T DK08774069 T DK 08774069T DK 2171034 T3 DK2171034 T3 DK 2171034T3
Authority
DK
Denmark
Prior art keywords
biopolymer
preparing
fermentation process
continuous perfusion
perfusion fermentation
Prior art date
Application number
DK08774069.2T
Other languages
English (en)
Inventor
Mads Laustsen
Original Assignee
Cmc Biolog As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38229532&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2171034(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cmc Biolog As filed Critical Cmc Biolog As
Application granted granted Critical
Publication of DK2171034T3 publication Critical patent/DK2171034T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DK08774069.2T 2007-06-13 2008-06-11 Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces DK2171034T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07110227A EP2014760A1 (en) 2007-06-13 2007-06-13 A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process
PCT/EP2008/057332 WO2008152075A1 (en) 2007-06-13 2008-06-11 A method for producing a biopolymer (e.g. polypeptide) in a continuous fermentation process

Publications (1)

Publication Number Publication Date
DK2171034T3 true DK2171034T3 (da) 2012-02-13

Family

ID=38229532

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08774069.2T DK2171034T3 (da) 2007-06-13 2008-06-11 Metode til fremstilling af en biopolymer i en kontinuerlig perfusionsgæringsproces

Country Status (6)

Country Link
US (1) US8679778B2 (da)
EP (2) EP2014760A1 (da)
AT (1) ATE530632T1 (da)
DK (1) DK2171034T3 (da)
ES (1) ES2375780T3 (da)
WO (1) WO2008152075A1 (da)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0714347A2 (pt) 2006-07-14 2013-05-07 Dsm Ip Assets Bv processo aperfeiÇoado para o cultivo de cÉlulas
WO2012045769A1 (en) 2010-10-05 2012-04-12 Novo Nordisk Health Care Ag Process for protein production
AU2011346515B2 (en) * 2010-12-23 2017-01-19 Gennova Biopharmaceuticals Ltd. Pharmaceutical compositions of tenecteplase
ES2969952T3 (es) 2011-04-22 2024-05-23 Wyeth Llc Composiciones relacionadas con una toxina mutante de Clostridium difficile y sus procedimientos
US10493151B2 (en) 2011-10-18 2019-12-03 Coherus Biosciences, Inc. Etanercept formulations stabilized with sodium chloride
SG11201401562RA (en) 2011-10-18 2014-09-26 Coherus Biosciences Inc Etanercept formulations stabilized with sodium chloride
GB2508569A (en) * 2011-11-02 2014-06-04 Univ Putra Malaysia A method for producing a biopolymer
EP2682168A1 (en) 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
JP6271536B2 (ja) 2012-07-09 2018-01-31 コヒラス・バイオサイエンシズ・インコーポレイテッド 肉眼不可視粒子の著しい低減を示すエタネルセプト製剤
AU2013315750B9 (en) 2012-09-11 2018-11-15 Coherus Biosciences, Inc. Correctly folded etanercept in high purity and excellent yield
BR122016023101B1 (pt) 2012-10-21 2022-03-22 Pfizer Inc Polipeptídeo, composição imunogênica que o compreende, bem como célula recombinante derivada de clostridium difficile
ES2842350T3 (es) 2013-03-19 2021-07-13 Cmc Biologics As Un procedimiento para la producción de un producto (por ejemplo, polipéptido) en un proceso de fermentación de cultivo celular continuo
SG11201507875RA (en) * 2013-03-26 2015-10-29 Coherus Biosciences Inc Protein production method
US11286292B2 (en) 2014-02-07 2022-03-29 Cmc Biologics A/S Bioreactor arrangement and continuous process for producing and capturing a biopolymer
WO2015158696A1 (en) * 2014-04-16 2015-10-22 Cmc Biologics A/S A high cell density fill and draw fermentation process
SG10202113019XA (en) * 2014-06-04 2021-12-30 Amgen Inc Methods for harvesting mammalian cell cultures
CN106414719B (zh) * 2014-06-13 2020-02-14 杰特有限公司 生物反应器中重组von Willebrand因子的改进生产
JP6530171B2 (ja) * 2014-09-09 2019-06-12 旭化成メディカル株式会社 培養産生物の回収方法
BR112017023624A2 (pt) 2015-05-29 2018-07-17 Glycotope Gmbh método de cultivo em pequena escala para células em suspensão
KR20230080504A (ko) * 2016-07-25 2023-06-07 리플리겐 코포레이션 교번 접선 유동식의 신속한 수확
WO2021143699A1 (en) * 2020-01-15 2021-07-22 Wuxi Biologics (Shanghai) Co. Ltd. An apparatus and a method for continuously harvesting a biological substance produced by a cultured cell
WO2021255690A2 (en) 2020-06-19 2021-12-23 Pfizer Inc. Immunogenic compositions against clostridioides (clostridium) difficile and methods thereof
JP2023546736A (ja) 2020-10-15 2023-11-07 エージーシー バイオロジクス，インコーポレーテッド 二重容器接線流濾過による連続的高細胞密度培養

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US5286646A (en) 1985-11-25 1994-02-15 Boehringer Mannheim Gmbh Method for mammalian cell culture
US4709442A (en) * 1986-10-21 1987-12-01 Advance Machine Company Portable extractor
DE3641824A1 (de) * 1986-12-06 1988-06-16 Bayer Ag Verfahren und vorrichtung zur kultivierung immobilisierter oder adhaerierter saeugerzellen sowie dessen verwendung bei der herstellung von proteinen
US4806484A (en) 1987-08-07 1989-02-21 Igb Products, Ltd. Perfusion airlift bioreactor
US5342781A (en) 1993-07-15 1994-08-30 Su Wei Wen W External-loop perfusion air-lift bioreactor
US6544424B1 (en) 1999-12-03 2003-04-08 Refined Technology Company Fluid filtration system
CA2441774A1 (en) * 2001-04-20 2002-10-31 E.I. Du Pont De Nemours And Company A product removal process for use in a biofermentation system
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
EP1720972B1 (en) 2004-03-05 2014-01-08 DSM IP Assets B.V. Process for cell culturing by continuous perfusion and alternating tangential flow

Also Published As

Publication number Publication date
EP2171034A1 (en) 2010-04-07
EP2171034B1 (en) 2011-10-26
US8679778B2 (en) 2014-03-25
US20100184149A1 (en) 2010-07-22
ES2375780T3 (es) 2012-03-06
ATE530632T1 (de) 2011-11-15
EP2014760A1 (en) 2009-01-14
WO2008152075A1 (en) 2008-12-18

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