ATE530639T1 - Mikroorganismen und verfahren zur verbesserten produktion von panthothenat - Google Patents

Mikroorganismen und verfahren zur verbesserten produktion von panthothenat

Info

Publication number
ATE530639T1
ATE530639T1 AT02746888T AT02746888T ATE530639T1 AT E530639 T1 ATE530639 T1 AT E530639T1 AT 02746888 T AT02746888 T AT 02746888T AT 02746888 T AT02746888 T AT 02746888T AT E530639 T1 ATE530639 T1 AT E530639T1
Authority
AT
Austria
Prior art keywords
microorganisms
methods
featured
panthothenate
invention features
Prior art date
Application number
AT02746888T
Other languages
English (en)
Inventor
R Yocum
Thomas Patterson
Janice Pero
Theron Hermann
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Application granted granted Critical
Publication of ATE530639T1 publication Critical patent/ATE530639T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT02746888T 2002-07-03 2002-07-03 Mikroorganismen und verfahren zur verbesserten produktion von panthothenat ATE530639T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/021336 WO2004005527A1 (en) 2002-07-03 2002-07-03 Microorganisms and processes for enhanced production of pantothenate

Publications (1)

Publication Number Publication Date
ATE530639T1 true ATE530639T1 (de) 2011-11-15

Family

ID=30113576

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02746888T ATE530639T1 (de) 2002-07-03 2002-07-03 Mikroorganismen und verfahren zur verbesserten produktion von panthothenat

Country Status (12)

Country Link
US (1) US20060099692A1 (de)
EP (1) EP1520030B1 (de)
JP (1) JP2005531326A (de)
CN (1) CN100455669C (de)
AT (1) ATE530639T1 (de)
AU (1) AU2002316575A1 (de)
CA (1) CA2491137A1 (de)
DK (1) DK1520030T3 (de)
HU (1) HUP0500383A2 (de)
MX (1) MXPA04012807A (de)
WO (1) WO2004005527A1 (de)
ZA (1) ZA200500949B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA04012812A (es) 2002-07-03 2005-02-24 Basf Ag Microorganismos y proceso para la produccion aumentada de pantotenato.
CN101448950B (zh) 2006-05-16 2014-02-12 帝斯曼知识产权资产管理有限公司 用于生产泛醇的工艺
US20110117087A1 (en) 2009-10-26 2011-05-19 Reinhard Franze Method for the production of a glycosylated immunoglobulin
WO2012175574A1 (en) 2011-06-21 2012-12-27 Dsm Ip Assets B.V. Increased pantothenate (vitamin b5) production
EP2723878B1 (de) 2011-06-21 2020-05-20 DSM IP Assets B.V. Herstellung von vitamin b5
SI3112372T1 (sl) * 2012-04-27 2019-04-30 Retrophin, Inc. Derivati pantotenata za zdravljenje nevroloških motenj
CN108456701B (zh) * 2018-03-23 2020-10-16 精晶药业股份有限公司 一种d-泛解酸内酯的制备方法
CN114058609B (zh) * 2020-12-01 2023-11-28 北京化工大学 一种h-蛋白及其应用
CN113637618B (zh) * 2021-06-04 2024-02-02 浙江工业大学 一种d-泛酸生产菌、构建方法及应用
CN115595328B (zh) * 2022-03-07 2026-02-13 中国科学院微生物研究所 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN116590209A (zh) * 2023-06-13 2023-08-15 浙江工业大学 一种产d-泛酸的基因工程菌、构建方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19846499A1 (de) * 1998-10-09 2000-04-20 Degussa Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen
MXPA02003017A (es) * 1999-09-21 2004-09-06 Basf Ag Metodos y microorganismos para la produccion de panto-compuestos.
BR0206587A (pt) * 2001-01-19 2005-12-13 Basf Ag Processo para a produção de uma composição de pantotenato livre de hmbpa, produto, composição de pantotenato livre de hmbpa, composição sintetizada por um microorganismo possuindo uma rota biossintética de pantotenato desregulada, microorganismo recombinante para a produção de composições de pantotenato livres de hmbpa, e, processo para a produção de uma composição de pantotenato: hmbpa seletivamente misturada
PL369009A1 (en) * 2001-01-19 2005-04-18 Basf Aktiengesellschaft Microorganisms and processes for enhanced production of pantothenate
EP1402046A1 (de) * 2001-07-03 2004-03-31 Degussa AG Verfahren zur fermentativen herstellung von pantothensäure und/oder ihren salzen

Also Published As

Publication number Publication date
MXPA04012807A (es) 2005-02-24
WO2004005527A1 (en) 2004-01-15
CA2491137A1 (en) 2004-01-15
EP1520030A1 (de) 2005-04-06
ZA200500949B (en) 2006-12-27
AU2002316575A1 (en) 2004-01-23
EP1520030B1 (de) 2011-10-26
CN1639349A (zh) 2005-07-13
CN100455669C (zh) 2009-01-28
EP1520030A4 (de) 2010-03-17
JP2005531326A (ja) 2005-10-20
US20060099692A1 (en) 2006-05-11
DK1520030T3 (da) 2012-02-27
HUP0500383A2 (hu) 2005-08-29

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