DK1520030T3 - Microorganismer og fremgangsmåder til forøget produktion af pantothenat - Google Patents

Microorganismer og fremgangsmåder til forøget produktion af pantothenat

Info

Publication number
DK1520030T3
DK1520030T3 DK02746888.3T DK02746888T DK1520030T3 DK 1520030 T3 DK1520030 T3 DK 1520030T3 DK 02746888 T DK02746888 T DK 02746888T DK 1520030 T3 DK1520030 T3 DK 1520030T3
Authority
DK
Denmark
Prior art keywords
microorganisms
pantothenate
methods
featured
invention features
Prior art date
Application number
DK02746888.3T
Other languages
English (en)
Inventor
R Rogers Yocum
Thomas A Patterson
Janice G Pero
Theron Hermann
Original Assignee
Basf Se
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Se filed Critical Basf Se
Application granted granted Critical
Publication of DK1520030T3 publication Critical patent/DK1520030T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1014—Hydroxymethyl-, formyl-transferases (2.1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK02746888.3T 2002-07-03 2002-07-03 Microorganismer og fremgangsmåder til forøget produktion af pantothenat DK1520030T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/021336 WO2004005527A1 (en) 2002-07-03 2002-07-03 Microorganisms and processes for enhanced production of pantothenate

Publications (1)

Publication Number Publication Date
DK1520030T3 true DK1520030T3 (da) 2012-02-27

Family

ID=30113576

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02746888.3T DK1520030T3 (da) 2002-07-03 2002-07-03 Microorganismer og fremgangsmåder til forøget produktion af pantothenat

Country Status (12)

Country Link
US (1) US20060099692A1 (da)
EP (1) EP1520030B1 (da)
JP (1) JP2005531326A (da)
CN (1) CN100455669C (da)
AT (1) ATE530639T1 (da)
AU (1) AU2002316575A1 (da)
CA (1) CA2491137A1 (da)
DK (1) DK1520030T3 (da)
HU (1) HUP0500383A2 (da)
MX (1) MXPA04012807A (da)
WO (1) WO2004005527A1 (da)
ZA (1) ZA200500949B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2491145A1 (en) 2002-07-03 2004-01-15 Basf Aktiengesellschaft Microorganisms and processes for enhanced production of pantothenate
CN101448950B (zh) 2006-05-16 2014-02-12 帝斯曼知识产权资产管理有限公司 用于生产泛醇的工艺
CN104928336B (zh) 2009-10-26 2020-05-08 弗·哈夫曼-拉罗切有限公司 用于生产糖基化免疫球蛋白的方法
WO2012175574A1 (en) 2011-06-21 2012-12-27 Dsm Ip Assets B.V. Increased pantothenate (vitamin b5) production
EP2723878B1 (en) 2011-06-21 2020-05-20 DSM IP Assets B.V. Vitamin b5 production
JP6254151B2 (ja) * 2012-04-27 2017-12-27 レトロフィン， インコーポレイテッド 神経系の障害の処置のためのパントテン酸誘導体
CN108456701B (zh) * 2018-03-23 2020-10-16 精晶药业股份有限公司 一种d-泛解酸内酯的制备方法
CN114134135B (zh) * 2020-12-01 2023-11-28 北京化工大学 一种h-蛋白突变体
CN113637618B (zh) * 2021-06-04 2024-02-02 浙江工业大学 一种d-泛酸生产菌、构建方法及应用
CN115595328B (zh) * 2022-03-07 2026-02-13 中国科学院微生物研究所 天冬氨酸脱羧酶在发酵生产维生素b5中的应用
CN116590209A (zh) * 2023-06-13 2023-08-15 浙江工业大学 一种产d-泛酸的基因工程菌、构建方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19846499A1 (de) * 1998-10-09 2000-04-20 Degussa Verfahren zur Herstellung von Pantothensäure durch Verstärkung von für Ketopantoat-Reduktase kodierenden Nukleotidsequenzen
BRPI0014115B8 (pt) * 1999-09-21 2021-05-25 Basf Ag métodos de produzir um panto-composto, pantotenato e beta-alanina, de aumentar a produção de um panto-composto e de edentificar compostos que modulam a atividade da pantotenato cinase, micro-organismo recombinante, vetor recombinante, e, vetor
CZ20031886A3 (cs) * 2001-01-19 2003-10-15 Basf Aktiengesellschaft Způsob přípravy pantothenátu ve vyšším výtěžku a mikroorganizmy používané při tomto způsobu
IL156613A0 (en) * 2001-01-19 2004-01-04 Basf Ag Processes for enhanced production of pantothenate
EP1402046A1 (en) * 2001-07-03 2004-03-31 Degussa AG Process for the fermentative preparation of d-pantothenic acid and/or salts thereof

Also Published As

Publication number Publication date
CN100455669C (zh) 2009-01-28
WO2004005527A1 (en) 2004-01-15
US20060099692A1 (en) 2006-05-11
EP1520030B1 (en) 2011-10-26
AU2002316575A1 (en) 2004-01-23
JP2005531326A (ja) 2005-10-20
EP1520030A4 (en) 2010-03-17
EP1520030A1 (en) 2005-04-06
MXPA04012807A (es) 2005-02-24
HUP0500383A2 (hu) 2005-08-29
ATE530639T1 (de) 2011-11-15
CN1639349A (zh) 2005-07-13
CA2491137A1 (en) 2004-01-15
ZA200500949B (en) 2006-12-27

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