ATE530898T1 - Vorrichtung zum messen der wechselstrommagnetisierung von materialien und verfahren zur erkennung von biomolekülen - Google Patents

Vorrichtung zum messen der wechselstrommagnetisierung von materialien und verfahren zur erkennung von biomolekülen

Info

Publication number
ATE530898T1
ATE530898T1 AT10154646T AT10154646T ATE530898T1 AT E530898 T1 ATE530898 T1 AT E530898T1 AT 10154646 T AT10154646 T AT 10154646T AT 10154646 T AT10154646 T AT 10154646T AT E530898 T1 ATE530898 T1 AT E530898T1
Authority
AT
Austria
Prior art keywords
magnetization
solution
molecules
measuring
sample
Prior art date
Application number
AT10154646T
Other languages
English (en)
Inventor
Chin-Yih Rex Hong
Herng-Er Horng
Hong-Chang Yang
Shieh-Yueh Yang
Original Assignee
Chin-Yih Rex Hong
Herng-Er Horng
Hong-Chang Yang
Shieh-Yueh Yang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chin-Yih Rex Hong, Herng-Er Horng, Hong-Chang Yang, Shieh-Yueh Yang filed Critical Chin-Yih Rex Hong
Application granted granted Critical
Publication of ATE530898T1 publication Critical patent/ATE530898T1/de

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302—Apparatus specially adapted for immunological test procedures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/54333—Modification of conditions of immunological binding reaction, e.g. use of more than one type of particle, use of chemical agents to improve binding, choice of incubation time or application of magnetic field during binding reaction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT10154646T 2009-02-27 2010-02-25 Vorrichtung zum messen der wechselstrommagnetisierung von materialien und verfahren zur erkennung von biomolekülen ATE530898T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12/394,043 US8193804B2 (en) 2005-11-16 2009-02-27 Device for measuring AC magnetization of materials

Publications (1)

Publication Number Publication Date
ATE530898T1 true ATE530898T1 (de) 2011-11-15

Family

ID=42224414

Family Applications (1)

Application Number Title Priority Date Filing Date
AT10154646T ATE530898T1 (de) 2009-02-27 2010-02-25 Vorrichtung zum messen der wechselstrommagnetisierung von materialien und verfahren zur erkennung von biomolekülen

Country Status (6)

Country Link
US (1) US8193804B2 (de)
EP (1) EP2224236B1 (de)
JP (1) JP5243472B2 (de)
CN (1) CN101819180B (de)
AT (1) ATE530898T1 (de)
TW (1) TWI412743B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7878071B2 (en) * 2006-12-22 2011-02-01 California Institute Of Technology Nanoindenter tip for uniaxial tension and compression testing
US10634741B2 (en) 2009-12-04 2020-04-28 Endomagnetics Ltd. Magnetic probe apparatus
US9427186B2 (en) * 2009-12-04 2016-08-30 Endomagnetics Ltd. Magnetic probe apparatus
CN102141540B (zh) * 2010-12-31 2012-07-25 中国科学院物理研究所 一种测量纳米磁性液体交流磁化率的装置和方法
US9546982B2 (en) 2012-12-10 2017-01-17 Arcelormittal Method and apparatus for determining the health and remaining service life of austenitic steel reformer tubes and the like
CN105283202B (zh) 2013-03-11 2019-04-23 安都磁学有限公司 用于淋巴结检测的低渗溶液
US9234877B2 (en) 2013-03-13 2016-01-12 Endomagnetics Ltd. Magnetic detector
EP2972514B1 (de) * 2013-03-13 2020-12-23 Endomagnetics Ltd. Magnetdetektor
US9239314B2 (en) 2013-03-13 2016-01-19 Endomagnetics Ltd. Magnetic detector
CA2902541A1 (en) 2013-03-14 2014-10-02 Bayer Healthcare Llc System error compensation of analyte concentration determinations
CN104237526B (zh) * 2013-06-18 2016-08-17 磁量生技股份有限公司 一种检测阿兹海默症罹患风险的系统
CN113558782B (zh) 2015-06-04 2024-12-10 安都磁学有限公司 用于磁标记定位（mml）的标记材料和形式
FR3038060B1 (fr) * 2015-06-26 2018-11-02 Atware Appareil de mesure d'une quantite de materiau superparamagnetique
BE1023946B1 (fr) * 2016-03-14 2017-09-19 Safran Aero Boosters Sa Capteur de particules dans un fluide d'un systeme de lubrification
WO2018023033A1 (en) 2016-07-29 2018-02-01 Western Michigan University Research Foundation Magnetic nanoparticle-based gyroscopic sensor
CN107462847A (zh) * 2017-06-27 2017-12-12 中国科学院电工研究所 一种磁纳米颗粒检测装置
FR3100616B1 (fr) * 2019-09-06 2021-09-17 Magnisense Se Dispositif de mesure comportant un générateur de champ magnétique et procédé de mesure associé
US12480934B1 (en) * 2020-10-23 2025-11-25 Mary Hitchcock Memorial Hospital, For Itself And On Behalf Of Dartmouth-Hitchcock Clinic System and method for monitoring molecular agents in vivo by estimating magnetic nanoparticle aggregation
CN115266501A (zh) * 2022-07-21 2022-11-01 上海交通大学 一种基于混频检测原理的浓度检测传感器
CN116448817A (zh) * 2023-03-10 2023-07-18 甘肃省科学院传感技术研究所 一种生物磁珠的快速检测系统及检测方法
CN116840094A (zh) * 2023-07-13 2023-10-03 上海交通大学 一种磁标记生物分子检测方法及测量系统

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001424A (en) * 1989-02-03 1991-03-19 Product Resources, Inc. Apparatus for measuring magnetic particles suspended in a fluid based on fluctuations in an induced voltage
DE69324242T2 (de) * 1992-01-31 1999-08-19 Northrop Grumman Corp. Wirbelstromsondensystem in einem array
GB2324154B (en) * 1997-04-01 2001-05-02 Michael John Hutchings Electromagnetic detector for measuring magnetic or conductive properties
RU2166751C1 (ru) * 2000-03-09 2001-05-10 Никитин Петр Иванович Способ анализа смеси биологических и/или химических компонентов с использованием магнитных частиц и устройство для его осуществления
DE50201174D1 (de) * 2002-07-25 2004-11-04 Amepa Verfahren und Vorrichtung zur Auswertung von Wirbelstrom-Messsignalen
DE10309132A1 (de) * 2003-02-28 2004-11-18 Forschungszentrum Jülich GmbH Verfahren und Vorrichtung zum selektiven Nachweis magnetischer Partikel
US7148678B1 (en) * 2003-03-26 2006-12-12 Targosz Thomas C Magnetic taggant system
JP4680587B2 (ja) * 2004-12-28 2011-05-11 旭化成株式会社 バイオセンサ、対象物測定方法、バイオセンサ用カートリッジ及び不織布
US7560289B2 (en) 2005-11-16 2009-07-14 Chin-Yih Rex Hong Methods of quantitatively measuring biomolecules
US20070111331A1 (en) * 2005-11-16 2007-05-17 Chin-Yih Rex Hong Diagnostic methods using magnetic nanoparticles

Also Published As

Publication number Publication date
CN101819180A (zh) 2010-09-01
TW201031915A (en) 2010-09-01
EP2224236B1 (de) 2011-10-26
US20090164161A1 (en) 2009-06-25
TWI412743B (zh) 2013-10-21
JP2010204101A (ja) 2010-09-16
US8193804B2 (en) 2012-06-05
CN101819180B (zh) 2012-07-25
EP2224236A1 (de) 2010-09-01
JP5243472B2 (ja) 2013-07-24

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