ATE532151T1 - Automatisierte segmentierung von bildstrukturen - Google Patents

Automatisierte segmentierung von bildstrukturen

Info

Publication number
ATE532151T1
ATE532151T1 AT07840517T AT07840517T ATE532151T1 AT E532151 T1 ATE532151 T1 AT E532151T1 AT 07840517 T AT07840517 T AT 07840517T AT 07840517 T AT07840517 T AT 07840517T AT E532151 T1 ATE532151 T1 AT E532151T1
Authority
AT
Austria
Prior art keywords
image structures
automated segmentation
extent
images
subcellular region
Prior art date
Application number
AT07840517T
Other languages
English (en)
Inventor
Harvey Ellis Cline
Paulo Ricardo Mendonca
Ali Can
Xiaodong Tao
Original Assignee
Gen Electric
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/500,028 external-priority patent/US8131476B2/en
Application filed by Gen Electric filed Critical Gen Electric
Priority claimed from PCT/US2007/074386 external-priority patent/WO2008024589A2/en
Application granted granted Critical
Publication of ATE532151T1 publication Critical patent/ATE532151T1/de

Links

Classifications

    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/0002Inspection of images, e.g. flaw detection
    • G06T7/0012Biomedical image inspection
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00Image analysis
    • G06T7/40Analysis of texture
    • G06T7/41Analysis of texture based on statistical description of texture
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/698Matching; Classification
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V40/00Recognition of biometric, human-related or animal-related patterns in image or video data
    • G06V40/10Human or animal bodies, e.g. vehicle occupants or pedestrians; Body parts, e.g. hands
    • G06V40/18Eye characteristics, e.g. of the iris
    • G06V40/193Preprocessing; Feature extraction
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/10Image acquisition modality
    • G06T2207/10116X-ray image
    • GPHYSICS
    • G06COMPUTING OR CALCULATING; COUNTING
    • G06TIMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00Indexing scheme for image analysis or image enhancement
    • G06T2207/30Subject of image; Context of image processing
    • G06T2207/30004Biomedical image processing
    • G06T2207/30068Mammography; Breast

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Multimedia (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Human Computer Interaction (AREA)
  • Radiology & Medical Imaging (AREA)
  • Quality & Reliability (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Probability & Statistics with Applications (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Image Analysis (AREA)
  • Image Processing (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT07840517T 2006-08-07 2007-07-26 Automatisierte segmentierung von bildstrukturen ATE532151T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/500,028 US8131476B2 (en) 2006-08-07 2006-08-07 System and method for co-registering multi-channel images of a tissue micro array
US11/606,582 US8060348B2 (en) 2006-08-07 2006-11-30 Systems for analyzing tissue samples
US11/680,063 US8036462B2 (en) 2006-08-07 2007-02-28 Automated segmentation of image structures
PCT/US2007/074386 WO2008024589A2 (en) 2006-08-07 2007-07-26 Automated segmentation of image structures

Publications (1)

Publication Number Publication Date
ATE532151T1 true ATE532151T1 (de) 2011-11-15

Family

ID=39029233

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07840517T ATE532151T1 (de) 2006-08-07 2007-07-26 Automatisierte segmentierung von bildstrukturen

Country Status (8)

Country Link
US (2) US8060348B2 (de)
EP (3) EP2050070A2 (de)
JP (2) JP4917647B2 (de)
AT (1) ATE532151T1 (de)
AU (1) AU2007284207B2 (de)
CA (1) CA2660113C (de)
ES (1) ES2374443T3 (de)
WO (1) WO2008021679A2 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8594410B2 (en) * 2006-08-28 2013-11-26 Definiens Ag Context driven image mining to generate image-based biomarkers
US9697582B2 (en) 2006-11-16 2017-07-04 Visiopharm A/S Methods for obtaining and analyzing images
WO2010017822A1 (en) 2008-08-15 2010-02-18 Visiopharm A/S A method and a system for determining a target in a biological sample by image analysis
US8170369B2 (en) * 2006-11-30 2012-05-01 Jeremy Adler Correlation between sets of data
US7783107B2 (en) * 2007-09-06 2010-08-24 Seiko Epson Corporation Characterization of a printed droplet
US8189884B2 (en) * 2008-03-26 2012-05-29 General Electric Company Methods for assessing molecular expression of subcellular molecules
US8135187B2 (en) 2008-03-26 2012-03-13 General Electric Company Method and apparatus for removing tissue autofluorescence
US8170320B2 (en) 2009-03-03 2012-05-01 Hologic, Inc. Mammography/tomosynthesis systems and methods automatically deriving breast characteristics from breast x-ray images and automatically adjusting image processing parameters accordingly
US8781201B2 (en) * 2009-03-04 2014-07-15 Robert E. Sandstrom Method of operating a pathology laboratory
US9111179B2 (en) 2009-09-18 2015-08-18 Rutgers, The State University Of New Jersey High-throughput biomarker segmentation utilizing hierarchical normalized cuts
US20110091081A1 (en) * 2009-10-16 2011-04-21 General Electric Company Method and system for analyzing the expression of biomarkers in cells in situ in their tissue of origin
US8824769B2 (en) * 2009-10-16 2014-09-02 General Electric Company Process and system for analyzing the expression of biomarkers in a cell
US8300938B2 (en) * 2010-04-09 2012-10-30 General Electric Company Methods for segmenting objects in images
US8730396B2 (en) * 2010-06-23 2014-05-20 MindTree Limited Capturing events of interest by spatio-temporal video analysis
US8634626B2 (en) * 2010-06-29 2014-01-21 The Chinese University Of Hong Kong Registration of 3D tomography images
WO2012123718A1 (en) * 2011-03-14 2012-09-20 The University Of Warwick Histology analysis
WO2012178069A1 (en) 2011-06-22 2012-12-27 The Johns Hopkins University System and device for characterizing cells
US8639013B2 (en) 2011-08-17 2014-01-28 General Electric Company System and methods for generating a brightfield image using fluorescent images
US9042630B2 (en) * 2011-10-26 2015-05-26 Definiens Ag Biomarker evaluation through image analysis
US8885912B2 (en) 2011-11-03 2014-11-11 General Electric Company Generate percentage of positive cells for biomarkers by normalizing and autothresholding the image intensity produced by immunohistochemistry technique
US9176032B2 (en) 2011-12-23 2015-11-03 General Electric Company Methods of analyzing an H and E stained biological sample
US8568991B2 (en) 2011-12-23 2013-10-29 General Electric Company Photoactivated chemical bleaching of dyes
US11573235B2 (en) 2012-03-30 2023-02-07 Leica Microsystems Cms Gmbh Methods for generating an image of a biological sample
US8737709B2 (en) 2012-04-30 2014-05-27 General Electric Company Systems and methods for performing correlation analysis on clinical outcome and characteristics of biological tissue
US9036888B2 (en) 2012-04-30 2015-05-19 General Electric Company Systems and methods for performing quality review scoring of biomarkers and image analysis methods for biological tissue
US20140024024A1 (en) * 2012-07-17 2014-01-23 General Electric Company Methods of detecting dna, rna and protein in biological samples
RU2015120176A (ru) 2012-12-11 2017-01-19 Клариент Дайагностик Сервисез, Инк. Фотоактивированное химическое обесцвечивание красителей
JP2016513794A (ja) 2013-03-06 2016-05-16 ゼネラル・エレクトリック・カンパニイ H&e染色された生体試料を分析する方法
US8995740B2 (en) * 2013-04-17 2015-03-31 General Electric Company System and method for multiplexed biomarker quantitation using single cell segmentation on sequentially stained tissue
US9953417B2 (en) * 2013-10-04 2018-04-24 The University Of Manchester Biomarker method
US9519823B2 (en) * 2013-10-04 2016-12-13 The University Of Manchester Biomarker method
CA2921325C (en) * 2013-10-07 2020-05-12 Ventana Medical Systems, Inc. Systems and methods for comprehensive multi-assay tissue analysis
US9322051B2 (en) 2013-10-07 2016-04-26 General Electric Company Probing of biological samples
EP4057215A1 (de) * 2013-10-22 2022-09-14 Eyenuk, Inc. Systeme und verfahren zur automatischen analyse von netzhautbildern
US20160307305A1 (en) * 2013-10-23 2016-10-20 Rutgers, The State University Of New Jersey Color standardization for digitized histological images
WO2015069824A2 (en) * 2013-11-06 2015-05-14 Lehigh University Diagnostic system and method for biological tissue analysis
US9430830B2 (en) * 2014-01-30 2016-08-30 Case Western Reserve University Spatially aware cell cluster (SPACCL) graphs
US10101322B2 (en) 2015-02-13 2018-10-16 General Electric Company Photoactivated chemical bleaching of dyes using borates
US9708349B2 (en) 2015-02-13 2017-07-18 General Electric Company Borates for photoactivated chemical bleaching
JP6841609B2 (ja) 2015-07-10 2021-03-10 3スキャン インコーポレイテッド 組織学的染色の空間的多重化
US10019796B2 (en) * 2015-10-16 2018-07-10 General Electric Company System and method for blood vessel analysis and quantification in highly multiplexed fluorescence imaging
CA3012360C (en) * 2016-03-01 2021-12-14 Ventana Medical Systems, Inc. Improved image analysis algorithms using control slides
US10896490B2 (en) * 2016-12-23 2021-01-19 Oregon Health & Science University Systems and methods for reflectance-based projection-resolved optical coherence tomography angiography
US11222194B2 (en) * 2016-12-30 2022-01-11 Ventana Medical Systems, Inc. Automated system and method for creating and executing a scoring guide to assist in the analysis of tissue specimen
CN111492368B (zh) * 2017-12-22 2024-03-05 文塔纳医疗系统公司 用于基于膜特征对组织图像中的细胞进行分类的系统和方法
TWI664424B (zh) * 2018-05-30 2019-07-01 國立臺灣科技大學 應用於協助癌症診斷的跨染色及多生物標記方法
EP3611695A1 (de) 2018-08-15 2020-02-19 Koninklijke Philips N.V. Erzeugung von anmerkungsdaten von gewebebildern
JP7228688B2 (ja) 2018-10-15 2023-02-24 ベンタナ メディカル システムズ, インコーポレイテッド 改善された核検出およびセグメンテーションを可能にする画像強化
US20200141475A1 (en) 2018-11-05 2020-05-07 Jtekt Corporation Ball screw device
WO2020124084A1 (en) * 2018-12-15 2020-06-18 The Brigham And Women's Hospital, Inc. Augmented digital microscopy for lesion analysis
WO2020227710A1 (en) * 2019-05-09 2020-11-12 H. Lee Moffitt Cancer Center And Research Institute, Inc. Systems and methods for slide image alignment
US12008747B2 (en) * 2019-07-29 2024-06-11 Case Western Reserve University Population-specific prediction of prostate cancer recurrence based on stromal morphology features
CN112191286B (zh) * 2020-09-29 2021-05-04 生物岛实验室 微流控芯片、用于空间组学测序及载玻片定位标识的方法

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5888743A (en) 1987-04-24 1999-03-30 Das; Kiron M. In vitro method for diagnosing benign Barrett's Epithelium
GB8813628D0 (en) 1988-06-09 1988-07-13 Shandon Southern Prod Immunostaining
US5995645A (en) 1993-08-18 1999-11-30 Applied Spectral Imaging Ltd. Method of cancer cell detection
US5859700A (en) 1995-11-22 1999-01-12 Kairos Scientific, Inc. High resolution imaging microscope (HIRIM) and uses thereof
DE19709348C2 (de) * 1996-05-29 1999-07-01 Schubert Walter Dr Md Automatisches Multi-Epitop-Ligand-Kartierungsverfahren
US20030036855A1 (en) * 1998-03-16 2003-02-20 Praelux Incorporated, A Corporation Of New Jersey Method and apparatus for screening chemical compounds
US6372439B2 (en) 1998-10-01 2002-04-16 James R. Goldenring Screen for gastric adenocarcinoma
US6573043B1 (en) * 1998-10-07 2003-06-03 Genentech, Inc. Tissue analysis and kits therefor
DE69903337T2 (de) * 1998-10-30 2003-08-21 Cellomics, Inc. Ein screeningsystem auf zellbasis
CN1384949A (zh) 1999-04-13 2002-12-11 色品视觉医学体系股份有限公司 组织重现和图像自动分析
US6195451B1 (en) 1999-05-13 2001-02-27 Advanced Pathology Ststems, Inc. Transformation of digital images
JP3534009B2 (ja) * 1999-09-24 2004-06-07 日本電気株式会社 輪郭抽出方法及び装置
US6835549B2 (en) 2000-02-24 2004-12-28 University Of Medicine & Dentistry Of New Jersey Immunoassay method for the diagnosis of gastric intestinal metaplasia associated with gastric carcinoma
AT411066B (de) 2000-10-24 2003-09-25 Steiner Georg E Verfahren und anordnung zur untersuchung von zellen
US6956961B2 (en) * 2001-02-20 2005-10-18 Cytokinetics, Inc. Extracting shape information contained in cell images
US7050620B2 (en) * 2001-03-30 2006-05-23 Heckman Carol A Method of assaying shape and structural features in cells
US7219016B2 (en) 2001-04-20 2007-05-15 Yale University Systems and methods for automated analysis of cells and tissues
US20040241688A1 (en) * 2001-07-19 2004-12-02 Cuneyt Bukusoglu Human tissue specific drug screening procedure
US7756305B2 (en) * 2002-01-23 2010-07-13 The Regents Of The University Of California Fast 3D cytometry for information in tissue engineering
CN1320358C (zh) * 2002-03-13 2007-06-06 Q3Dm有限责任公司 自动彩色分割和测量细胞区室的分部定位强度的最小显著性反应的系统和方法
EP1422526A1 (de) 2002-10-28 2004-05-26 MTM Laboratories AG Verfahren zur verbesserten Diagnose von Dysplasien
DE60202081T2 (de) 2002-10-28 2005-12-08 Mtm Laboratories Ag Verfahren zur verbesserten Diagnose von Dysplasien
US20040197839A1 (en) 2003-04-04 2004-10-07 Bioview Ltd. Methods of detecting cancer cells in biological samples
US7467119B2 (en) * 2003-07-21 2008-12-16 Aureon Laboratories, Inc. Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
US7483554B2 (en) * 2003-11-17 2009-01-27 Aureon Laboratories, Inc. Pathological tissue mapping
US7461048B2 (en) * 2003-07-21 2008-12-02 Aureon Laboratories, Inc. Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition
US6995020B2 (en) * 2003-07-21 2006-02-07 Aureon Laboratories, Inc. Methods and compositions for the preparation and use of fixed-treated cell-lines and tissue in fluorescence in situ hybridization
US7505948B2 (en) * 2003-11-18 2009-03-17 Aureon Laboratories, Inc. Support vector regression for censored data
WO2005022362A2 (en) * 2003-09-02 2005-03-10 The Regents Of The University Of Michigan Chemical address tags
EP1728210A2 (de) * 2004-02-27 2006-12-06 Aureon Laboratories, Inc. Verfahren und system zur vorhersage des auftretens eines ereignisses
DE602005024021D1 (de) 2004-08-10 2010-11-18 Oncotherapy Science Inc GEN ANLN IN VERBINDUNG MIT NICHT-KLEINZELLIGEM LUNGENKREBS UND SEINE WECHSELWIRKUNGEN MIT RhoA
US7933435B2 (en) * 2005-11-21 2011-04-26 Vala Sciences, Inc. System, method, and kit for processing a magnified image of biological material to identify components of a biological object
US8367351B2 (en) * 2006-05-05 2013-02-05 Historx, Inc. Methods for determining signal transduction activity in tumors
EP2027465A2 (de) * 2006-05-17 2009-02-25 Cellumen, Inc. Verfahren für automatisierte gewebeanalyse
JP2009544007A (ja) * 2006-07-13 2009-12-10 イェール・ユニバーシティー バイオマーカーの細胞内局在性に基づいて癌予後を行う方法
US8305579B2 (en) 2006-11-16 2012-11-06 Thomas Pirrie Treynor Sequential analysis of biological samples
US7741045B2 (en) * 2006-11-16 2010-06-22 General Electric Company Sequential analysis of biological samples
US7629125B2 (en) * 2006-11-16 2009-12-08 General Electric Company Sequential analysis of biological samples

Also Published As

Publication number Publication date
WO2008021679A2 (en) 2008-02-21
US8060348B2 (en) 2011-11-15
EP2049678A2 (de) 2009-04-22
ES2374443T3 (es) 2012-02-16
AU2007284207B2 (en) 2012-05-24
US8036462B2 (en) 2011-10-11
EP2050070A2 (de) 2009-04-22
EP2070047A2 (de) 2009-06-17
JP2010500655A (ja) 2010-01-07
AU2007284207A1 (en) 2008-02-21
US20080031521A1 (en) 2008-02-07
JP5058259B2 (ja) 2012-10-24
CA2660113A1 (en) 2008-02-21
WO2008021679A3 (en) 2009-03-12
US20080033657A1 (en) 2008-02-07
CA2660113C (en) 2014-11-18
JP4917647B2 (ja) 2012-04-18
EP2070047B1 (de) 2011-11-02
JP2010500572A (ja) 2010-01-07

Similar Documents

Publication Publication Date Title
ATE532151T1 (de) Automatisierte segmentierung von bildstrukturen
Li et al. Weakly supervised histopathology image segmentation with self-attention
HK1201180A1 (en) Method and system for analyzing biological specimens by spectral imaging
BR112012023504A2 (pt) método de reproduzir som estereofônico, equipamento para reproduzir som estereofônico, e meio de gravação legível por computador.
EA200801928A1 (ru) Система и способ моделирования полёта
BR112012021792A2 (pt) "método de adição de informações de definição de imagem a um sinal de imagem a um sinal de imagem de entrada, aparelho de análise de imagem para adicionar informações de definição de imagem às informações de pixel de imagem de um sinal de imagem de entrada, método de processamento de um sinal de imagem de entrada a ser renderizado com base nas informações de definição de imagem relacionadas ao sinal de imagem de entrada, aparelho para processar um sinal de imagem de entrada a ser renderizado com base nas informações de definição de imagem relacionadas ao sinal de imagem de entrada e sinal de imagem"
EP2405381A3 (de) Lernbildvorlagen zur Inhaltsverankerung und Datenextraktion
EP2461272A3 (de) Fahrunterstützungssystem und Fahrunterstützungsverfahren
WO2015030961A3 (en) Acquiring online meeting data relating to an online meeting
WO2012143561A3 (en) Analyzing the expression of biomarkers in cells with clusters
ES2528321T3 (es) Detección de a-fucosilación en anticuerpos
EP2700364A3 (de) Verfahren und Vorrichtung zum Anzeigen eines Ultraschallbildes
EP1865447A3 (de) Informationsverarbeitungsvorrichtung, Informationsverarbeitungsverfahren und Computerprogramm
EP2426621A3 (de) Informationsverarbeitungsvorrichtung und Informationsverarbeitungsverfahren
EP2688021A3 (de) Verfahren zur Identifikation der maximalen Packungsdichte von automatischen Lagern mit Verschiebeplatten
IL172591A0 (en) A system and method of processing radar information
BR112022024406A2 (pt) Modelo de aprendizado por máquina para análise de dados de patologia a partir de locais metastáticos
WO2008027393A3 (en) Computer aided detection of bone metastasis
BR112022001743A2 (pt) Método para localizar região de interesse em tecido, dispositivo, aparelho e meio de armazenamento
EP2437176A3 (de) System und Verfahren zur Verwendung eines n-fach-Cache
EP1783204A3 (de) Handhabung und Abbildung biologischer Proben
EP2610641A3 (de) Ultraschall und System zum Erzeugen von Doppler Ultraschallbildern
WO2007126901A3 (en) Apparatus and method for predicting disease
WO2007124234A3 (en) Systems and methods for displaying a cellular abnormality
EP2506560A3 (de) Bildverarbeitungsvorrichtung, Bildverarbeitungsverfahren und Speichermedium