ATE532553T1 - Transdermales arzneiverabreichungsgerät mit mikronadeln - Google Patents

Transdermales arzneiverabreichungsgerät mit mikronadeln

Info

Publication number
ATE532553T1
ATE532553T1 AT07713903T AT07713903T ATE532553T1 AT E532553 T1 ATE532553 T1 AT E532553T1 AT 07713903 T AT07713903 T AT 07713903T AT 07713903 T AT07713903 T AT 07713903T AT E532553 T1 ATE532553 T1 AT E532553T1
Authority
AT
Austria
Prior art keywords
microneedles
absorbent
drug
dissolving solution
disposed
Prior art date
Application number
AT07713903T
Other languages
English (en)
Inventor
Seiji Tokumoto
Toshiyuki Matsudo
Tetsuji Kuwahara
Original Assignee
Hisamitsu Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co filed Critical Hisamitsu Pharmaceutical Co
Application granted granted Critical
Publication of ATE532553T1 publication Critical patent/ATE532553T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023—Drug applicators using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/003—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a lumen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046—Solid microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303—Constructional details
    • A61N1/306—Arrangements where at least part of the apparatus is introduced into the body

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT07713903T 2006-02-10 2007-02-07 Transdermales arzneiverabreichungsgerät mit mikronadeln ATE532553T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006034483 2006-02-10
PCT/JP2007/052143 WO2007091608A1 (ja) 2006-02-10 2007-02-07 マイクロニードル付き経皮薬物投与装置

Publications (1)

Publication Number Publication Date
ATE532553T1 true ATE532553T1 (de) 2011-11-15

Family

ID=38345204

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07713903T ATE532553T1 (de) 2006-02-10 2007-02-07 Transdermales arzneiverabreichungsgerät mit mikronadeln

Country Status (5)

Country Link
US (1) US8419708B2 (de)
EP (1) EP1992386B1 (de)
JP (1) JPWO2007091608A1 (de)
AT (1) ATE532553T1 (de)
WO (1) WO2007091608A1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1992386B1 (de) 2006-02-10 2011-11-09 Hisamitsu Pharmaceutical Co., Inc. Transdermales arzneiverabreichungsgerät mit mikronadeln
US20100221314A1 (en) * 2007-10-18 2010-09-02 Hisamitsu Pharmaceutical Co., Inc. Microneedle Device
USD610690S1 (en) 2008-04-16 2010-02-23 Hisamitsu Pharmaceutical Co., Inc. Combined medical patch and package
USD617463S1 (en) 2008-04-16 2010-06-08 Hisamitsu Pharmaceutical Co., Inc. Combined medical patch and package
EP2433664B1 (de) * 2008-06-06 2016-08-10 Wockhardt Limited Vorrichtung zur Freisetzung von biologischem Material
JP5476062B2 (ja) * 2008-07-25 2014-04-23 南部化成株式会社 経皮投薬デバイス
KR101039078B1 (ko) * 2009-08-04 2011-06-07 (주)마이티시스템 이동되는 약물 저장 캡슐이 있는 미세바늘 약물 전달 시스템
WO2010070628A1 (en) * 2008-12-19 2010-06-24 Janisys Limited A fluid transfer device and an active substance cartridge for the fluid transfer device, and a method for controlling the pressure at which an active substance is delivered to a subject from a fluid transfer device
EP2383013A4 (de) * 2008-12-26 2012-11-28 Hisamitsu Pharmaceutical Co Mikronadelvorrichtung
KR101033513B1 (ko) * 2009-01-20 2011-05-09 (주)마이티시스템 미세바늘을 이용한 유용성분 피부전달용 용기
EP2392378B1 (de) * 2009-01-30 2017-03-15 Hisamitsu Pharmaceutical Co., Inc. Mikronadelvorrichtung
US8891425B2 (en) * 2009-04-10 2014-11-18 Qualcomm Incorporated Paging access terminals in a wireless communications system
KR101759354B1 (ko) 2009-06-10 2017-07-18 히사미쓰 세이야꾸 가부시키가이샤 마이크로니들 디바이스
EP2457592B1 (de) 2009-07-23 2020-09-16 Hisamitsu Pharmaceutical Co., Inc. Mikronadelarray
US8834423B2 (en) 2009-10-23 2014-09-16 University of Pittsburgh—of the Commonwealth System of Higher Education Dissolvable microneedle arrays for transdermal delivery to human skin
JPWO2011105496A1 (ja) 2010-02-24 2013-06-20 久光製薬株式会社 マイクロニードルデバイス
KR20110115377A (ko) * 2010-04-15 2011-10-21 (주)마이티시스템 유출량 조절이 가능한 미세바늘 뚜껑 시스템
MX345837B (es) 2010-04-28 2017-02-16 Kimberly-Clark Worldwide Incorporated Dispositivo para la entrega de un medicamento para la artritis reumatoide.
WO2011135531A2 (en) 2010-04-28 2011-11-03 Kimberly-Clark Worldwide, Inc. MEDICAL DEVICES FOR DELIVERY OF siRNA
EP2563455A4 (de) 2010-04-28 2014-02-19 Kimberly Clark Co Verfahren zur erhöhung der durchlässigkeit einer epithelialbarriere
KR20130058012A (ko) 2010-04-28 2013-06-03 킴벌리-클라크 월드와이드, 인크. 사출 성형된 마이크로니들 어레이 및 마이크로니들 어레이의 형성 방법
EP2954916A3 (de) * 2010-08-13 2016-04-20 Seventh Sense Biosystems, Inc. Klinische und/oder verbraucherverfahren und -vorrichtungen
AU2015201453B2 (en) * 2010-09-13 2017-04-27 Ndm Technologies Limited Devices for transdermal drug delivery
JP5695731B2 (ja) * 2011-02-24 2015-04-08 久光製薬株式会社 マイクロニードルデバイス用生理活性非水組成物及びマイクロニードル上に付着している生理活性非水組成物
US8696637B2 (en) 2011-02-28 2014-04-15 Kimberly-Clark Worldwide Transdermal patch containing microneedles
US8636696B2 (en) 2011-06-10 2014-01-28 Kimberly-Clark Worldwide, Inc. Transdermal device containing microneedles
EP2764887B1 (de) 2011-10-06 2020-12-02 Hisamitsu Pharmaceutical Co., Inc. Applikator
US20170246439A9 (en) 2011-10-27 2017-08-31 Kimberly-Clark Worldwide, Inc. Increased Bioavailability of Transdermally Delivered Agents
JP6535464B2 (ja) 2011-10-27 2019-06-26 ソレント・セラピューティクス・インコーポレイテッド 生理活性薬剤の送達のための移植可能な装置
MX343262B (es) 2011-10-27 2016-10-28 Kimberly Clark Co Administración transdérmica de agentes bioactivos de alta viscosidad.
DE102011089752A1 (de) 2011-12-23 2013-06-27 Robert Bosch Gmbh Verfahren zur Herstellung von Silizium-Mikronadelarrays mit Löchern und Mikronadelarray
US8632501B2 (en) * 2012-03-01 2014-01-21 Joseph Wayne Kraft Device for the rapid injection of local anesthesia through a plurality of needles
HK1209658A1 (en) 2012-05-01 2016-04-08 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Tip-loaded microneedle arrays for transdermal insertion
JP6003338B2 (ja) * 2012-07-26 2016-10-05 凸版印刷株式会社 針状体パッケージ
CN105073102B (zh) 2012-10-01 2018-06-19 香港科技大学 透皮贴装置
EP2961471B1 (de) 2013-02-28 2023-10-25 Sorrento Therapeutics, Inc. Vorrichtung zur transdermalen wirkstofffreisetzung
WO2014132239A1 (en) 2013-02-28 2014-09-04 Kimberly-Clark Worldwide, Inc. Drug delivery device
KR102083658B1 (ko) * 2013-07-19 2020-03-02 주식회사 엘지생활건강 내부 유로를 가진 마이크로니들 시스템
JP7229653B2 (ja) * 2013-09-30 2023-02-28 ジョージア テック リサーチ コーポレイション マイクロニードルパッチ、システム、及び方法
US10238847B2 (en) * 2014-01-22 2019-03-26 Geelux Holdings, Ltd. Devices and methods for transdermal drug delivery
ES3059965T3 (en) 2014-04-24 2026-03-24 Georgia Tech Res Inst Microneedles and methods of manufacture thereof
CN106535979B (zh) 2014-04-30 2018-12-21 金伯利-克拉克环球有限公司 透皮药物递送设备的控制器部分和方法
WO2015168210A1 (en) 2014-04-30 2015-11-05 Kimberly-Clark Worldwide, Inc. Transdermal drug delivery apparatus and methods
CA3160375C (en) 2014-04-30 2024-04-30 Sorrento Therapeutics, Inc. Receptacle portion of transdermal drug delivery apparatus and methods
CN106413798A (zh) 2014-05-06 2017-02-15 穆医药有限公司 非侵入性剂施用器
EP3218043A4 (de) 2014-11-12 2018-07-11 Mupharma Pty Ltd Nichtinvasiver wirkstoffapplikator
US10441768B2 (en) 2015-03-18 2019-10-15 University of Pittsburgh—of the Commonwealth System of Higher Education Bioactive components conjugated to substrates of microneedle arrays
WO2017066768A1 (en) 2015-10-16 2017-04-20 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Mullti-component biio-active drug delivery and controlled release to the skin by microneedle array devices
GB2544559A (en) * 2015-11-23 2017-05-24 Owen Mumford Ltd Apparatus for medicament delivery
US11744889B2 (en) 2016-01-05 2023-09-05 University of Pittsburgh—of the Commonwealth System of Higher Education Skin microenvironment targeted delivery for promoting immune and other responses
KR101898473B1 (ko) * 2016-11-01 2018-09-13 (주)에보소닉 음파진동을 이용한 마이크로니들 미용장치
EP3595515A4 (de) 2017-03-14 2020-12-30 University of Connecticut Biologisch abbaubarer drucksensor
CN108785844A (zh) * 2017-05-02 2018-11-13 江苏金甙生物技术有限公司 一种冲击波可触变药物及护肤品微流体输送装置
GB201716391D0 (en) 2017-10-06 2017-11-22 Xobaderm Ltd Kit for delivery of an active compound into a biological barrier
EP3875141B1 (de) * 2018-10-31 2022-12-14 FUJIFILM Corporation Mikronadelfeldvorrichtung
US11826495B2 (en) 2019-03-01 2023-11-28 University Of Connecticut Biodegradable piezoelectric ultrasonic transducer system
JP2022532215A (ja) 2019-05-16 2022-07-13 ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション 皮膚および非皮膚薬物送達のためのアンダーカット特徴を有するマイクロニードルアレイ
CN110860029B (zh) * 2019-10-09 2022-04-22 杭州未名信科科技有限公司 一种经皮给药贴及经皮给药方法
US11745001B2 (en) 2020-03-10 2023-09-05 University Of Connecticut Therapeutic bandage
US12491290B2 (en) 2020-06-08 2025-12-09 University Of Connecticut Biodegradable piezoelectric composite materials
FR3113843B1 (fr) * 2020-09-07 2024-03-15 Oreal Kit et traitement cosmetique utilisant une feuille de micro-aiguilles
KR102297883B1 (ko) * 2021-02-17 2021-09-03 주식회사 지엘캄퍼니 마이크로 니들조립체
US20230270448A1 (en) * 2022-02-09 2023-08-31 Golden Hour Medical, Llc Automated emergency pneumatic tourniquet
KR102857955B1 (ko) * 2022-04-06 2025-09-11 서울대학교산학협력단 약물 주입 장치
US12070229B1 (en) 2023-09-14 2024-08-27 Golden Hour Medical, Inc. Method, device, and network for stopping blood loss

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4573996A (en) * 1984-01-03 1986-03-04 Jonergin, Inc. Device for the administration of an active agent to the skin or mucosa
JPS63102768A (ja) * 1986-10-20 1988-05-07 山之内製薬株式会社 イオントフオレ−シス用の新規プラスタ−構造体
EP0429842B1 (de) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
JP2808503B2 (ja) 1991-09-25 1998-10-08 三菱電機ホーム機器株式会社 電気掃除機用床ブラシ
US5310404A (en) * 1992-06-01 1994-05-10 Alza Corporation Iontophoretic delivery device and method of hydrating same
JP2533039B2 (ja) 1992-07-02 1996-09-11 照男 小林 滅菌用液化混合ガス気化供給装置
US7184826B2 (en) 1996-06-18 2007-02-27 Alza Corporation Device and method for enhancing transdermal flux of agents being delivered or sampled
JPH114655A (ja) 1997-06-16 1999-01-12 Ishikawajima Harima Heavy Ind Co Ltd 食鳥腿肉のホック部カット装置
JP4412874B2 (ja) * 1999-06-08 2010-02-10 アルテア セラピューティクス コーポレイション 薄膜組織インターフェイスデバイスを使用する生物学的膜のミクロポレーションのための装置、およびそのための方法
US6656147B1 (en) 2000-07-17 2003-12-02 Becton, Dickinson And Company Method and delivery device for the transdermal administration of a substance
GB0017999D0 (en) 2000-07-21 2000-09-13 Smithkline Beecham Biolog Novel device
ES2333849T3 (es) * 2001-04-20 2010-03-02 Alza Corporation Disposicion de microsalientes que presenta un revestimiento que contiene un agente beneficioso.
US6881203B2 (en) * 2001-09-05 2005-04-19 3M Innovative Properties Company Microneedle arrays and methods of manufacturing the same
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6908453B2 (en) * 2002-01-15 2005-06-21 3M Innovative Properties Company Microneedle devices and methods of manufacture
US7858112B2 (en) * 2002-02-28 2010-12-28 Lintec Corporation Percutaneous absorption system and percutaneous absorption method
US7047070B2 (en) 2002-04-02 2006-05-16 Becton, Dickinson And Company Valved intradermal delivery device and method of intradermally delivering a substance to a patient
US7015262B2 (en) * 2002-05-01 2006-03-21 Lifescan, Inc. Hydrophilic coatings for medical implements
EP1656178A1 (de) 2003-08-04 2006-05-17 Alza Corporation Verfahren und vorrichtung zur verbesserung des flusses transdermaler agentien
AU2004285481A1 (en) * 2003-10-24 2005-05-12 Alza Corporation Apparatus and method for enhancing transdermal drug delivery
JP4721902B2 (ja) * 2003-12-26 2011-07-13 久光製薬株式会社 用時活性化型イオントフォレーシスデバイス
EP1992386B1 (de) 2006-02-10 2011-11-09 Hisamitsu Pharmaceutical Co., Inc. Transdermales arzneiverabreichungsgerät mit mikronadeln
JP5084180B2 (ja) 2006-06-06 2012-11-28 トヨタ自動車株式会社 チューブ型固体電解質燃料電池

Also Published As

Publication number Publication date
US8419708B2 (en) 2013-04-16
EP1992386B1 (de) 2011-11-09
JPWO2007091608A1 (ja) 2009-07-02
EP1992386A4 (de) 2010-03-17
WO2007091608A1 (ja) 2007-08-16
US20090030365A1 (en) 2009-01-29
EP1992386A1 (de) 2008-11-19

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