ATE532874T1 - Verfahren zum nachweis in hefe für mittels die proteinfaltung beeinflussen - Google Patents
Verfahren zum nachweis in hefe für mittels die proteinfaltung beeinflussenInfo
- Publication number
- ATE532874T1 ATE532874T1 AT06024213T AT06024213T ATE532874T1 AT E532874 T1 ATE532874 T1 AT E532874T1 AT 06024213 T AT06024213 T AT 06024213T AT 06024213 T AT06024213 T AT 06024213T AT E532874 T1 ATE532874 T1 AT E532874T1
- Authority
- AT
- Austria
- Prior art keywords
- disease
- protein
- yeast
- detecting
- protein folding
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 2
- 230000012846 protein folding Effects 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000012216 screening Methods 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 230000001537 neural effect Effects 0.000 abstract 1
- 230000004770 neurodegeneration Effects 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000004845 protein aggregation Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4703—Regulators; Modulating activity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2835—Movement disorders, e.g. Parkinson, Huntington, Tourette
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26915701P | 2001-02-15 | 2001-02-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE532874T1 true ATE532874T1 (de) | 2011-11-15 |
Family
ID=23026039
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02718994T ATE382704T1 (de) | 2001-02-15 | 2002-02-15 | Verfahren zum nachweis in hefe für mittels die proteinfaltung beeinflussen |
| AT06024213T ATE532874T1 (de) | 2001-02-15 | 2002-02-15 | Verfahren zum nachweis in hefe für mittels die proteinfaltung beeinflussen |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02718994T ATE382704T1 (de) | 2001-02-15 | 2002-02-15 | Verfahren zum nachweis in hefe für mittels die proteinfaltung beeinflussen |
Country Status (8)
| Country | Link |
|---|---|
| US (7) | US7045290B2 (de) |
| EP (2) | EP1392849B2 (de) |
| JP (2) | JP4344138B2 (de) |
| AT (2) | ATE382704T1 (de) |
| AU (3) | AU2002250102B2 (de) |
| CA (1) | CA2438661C (de) |
| DE (1) | DE60224383T3 (de) |
| WO (1) | WO2002065136A2 (de) |
Families Citing this family (60)
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|---|---|---|---|---|
| US7799535B1 (en) | 1997-12-09 | 2010-09-21 | Arch Development Corporation | Methods for identifying factors that control the folding of amyloid proteins of diverse origin |
| US7045290B2 (en) * | 2001-02-15 | 2006-05-16 | The University Of Chicago | Yeast screens for treatment of human disease |
| US8183350B2 (en) | 2002-05-04 | 2012-05-22 | Acorda Therapeutics, Inc. | Compositions and methods for promoting neuronal outgrowth |
| KR20050053607A (ko) * | 2002-08-07 | 2005-06-08 | 유니버시티 오브 델라웨어 | 단백질 오조립 및 응집을 나타내는 질병을 치료하기 위한조성물 및 방법 |
| FR2846009B1 (fr) | 2002-10-18 | 2007-10-12 | Centre Nat Rech Scient | Criblage de molecules a activite anti-prion:kits, methodes et molecules criblees |
| FR2846008B1 (fr) * | 2002-10-18 | 2006-06-02 | Centre Nat Rech Scient | Criblage de molecules a activite anti-prion:kits, methodes et molecules criblees |
| CA2522497A1 (en) * | 2003-04-16 | 2004-11-04 | Whitehead Institute For Biomedical Research | Yeast ectopically expressing abnormally processed proteins and uses therefor |
| EP3211084B1 (de) * | 2003-05-16 | 2019-03-27 | Acorda Therapeutics, Inc. | Proteoglycan-abbauende mutanten zur behandlung des zns |
| US7959914B2 (en) | 2003-05-16 | 2011-06-14 | Acorda Therapeutics, Inc. | Methods of reducing extravasation of inflammatory cells |
| US20060008894A1 (en) * | 2003-07-11 | 2006-01-12 | Gerard Griffioen | Yeast model for amyloidogenic protein toxicity |
| US7452670B2 (en) | 2003-12-04 | 2008-11-18 | University Of Washington | Methods of identifying agents that diminish cellular toxicity associated with an α-synuclein polypeptide of Parkinson's disease in yeast |
| WO2005108599A2 (en) * | 2004-05-05 | 2005-11-17 | Whitehead Institute For Biomedical Research | Compositions and methods for treatment of protein misfolding diseases |
| MXPA06013345A (es) | 2004-05-18 | 2008-10-31 | Acorda Therapeutics Inc | Metodos para purificar condrointinasa y sus formulaciones estables. |
| EP1754052B1 (de) * | 2004-06-03 | 2015-07-22 | Phylogica Limited | Modulatoren biochemischer eigenschaften |
| CA2580767A1 (en) | 2004-09-17 | 2006-03-30 | Whitehead Institute For Biomedical Research | Compounds, compositions and methods of inhibiting alpha-synuclein toxicity |
| US7618793B2 (en) * | 2004-10-20 | 2009-11-17 | The Regents Of The University Of Washington | Identifying agents for decreasing cellular toxicity associated with huntingin polypeptide |
| US7504227B2 (en) * | 2004-10-20 | 2009-03-17 | University Of Washington | Drug targets for the treatment of neurodegenerative disorders |
| JP4939432B2 (ja) | 2004-12-01 | 2012-05-23 | ホワイトヘッド インスティテュート フォー バイオメディカル リサーチ | α−シヌクレイン毒性のモジュレーター |
| US9018003B2 (en) | 2005-05-13 | 2015-04-28 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| US7368258B1 (en) * | 2005-06-06 | 2008-05-06 | University Of Maryland, Baltimore County | Devices and methods for profiling enzyme substrates |
| JP5189985B2 (ja) | 2005-09-26 | 2013-04-24 | アコーダ セラピューティクス、インク. | コンドロイチナーゼabci変異体を用いた組成物およびその使用方法 |
| US20100273776A1 (en) * | 2006-03-29 | 2010-10-28 | FOLDRx PHARMACEUTICALS, INC | Inhibition of alpha-synuclein toxicity |
| GB0610792D0 (en) * | 2006-06-02 | 2006-07-12 | Remynd Nv | Methods and tools for the screening of factors affecting protein misfolding |
| CA3009034C (en) | 2006-10-10 | 2020-08-18 | Acorda Therapeutics, Inc. | Compositions and methods of using chondroitinase abci mutants |
| WO2008067070A2 (en) | 2006-10-19 | 2008-06-05 | California Institute Of Technology | Compositions and methods for producing benzylisoquinolines alkaloids |
| US8323952B2 (en) * | 2007-12-13 | 2012-12-04 | Archer Daniels Midland Company | Alcoholic xylose fermentation at high temperatures by the thermotolerant yeast Hansenula polymorpha |
| WO2009086306A1 (en) | 2007-12-21 | 2009-07-09 | Whitehead Institute For Biomedical Research | Modulators of alpha-synuclein toxicity |
| US9738898B2 (en) | 2008-02-15 | 2017-08-22 | Whitehead Institute For Biomedical Research | Yeast cells expressing TAR DNA-binding protein 43 and uses therefor |
| ES2418459B1 (es) * | 2008-10-09 | 2014-08-12 | Universitat Autònoma De Barcelona | Relacionando agregación proteica con supervivencia de levadura |
| US8865411B2 (en) | 2009-03-26 | 2014-10-21 | National Institutes Of Health (Nih) | Methods of identifying modulators of TDP-43 mediated cellular toxicity |
| EP2524040B1 (de) | 2010-01-12 | 2017-03-15 | The Whitehead Institute for Biomedical Research | Hefezellen zur expression von amyloid-beta und verwendungen davon |
| CN101858910B (zh) * | 2010-03-25 | 2013-03-27 | 辽宁大学 | 一种在蛋白质水平精确定量检测抗朊病毒药物作用效果的方法 |
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| US10642376B2 (en) | 2012-11-28 | 2020-05-05 | Intel Corporation | Multi-function stylus with sensor controller |
| HK1220233A1 (zh) * | 2013-03-15 | 2017-04-28 | 怀特黑德生物医学研究院 | 用於神经变性疾病的细胞性发现平台 |
| DK3553177T3 (da) | 2013-03-15 | 2021-02-15 | Univ Leland Stanford Junior | Benzylisoquinolinalkaloider (bia) som producerer mikrober, og fremgangsmåder til fremstilling og anvendelse deraf |
| CN112410379B (zh) | 2013-11-04 | 2024-12-31 | 小利兰·斯坦福大学托管委员会 | 产生苄基异喹啉生物碱(bia)前体的微生物以及制备和使用所述前体的方法 |
| CH709681A1 (de) | 2014-05-21 | 2015-11-30 | Explo Engineering Ag | Pulsdetonationsantrieb. |
| EP3155003B9 (de) | 2014-06-13 | 2020-12-30 | Whitehead Institute for Biomedical Research | Amyloid-beta-expression-konstrukte und verwendungen davon |
| CA2954738A1 (en) * | 2014-07-29 | 2016-02-04 | Neurimmune Holding Ag | Human-derived anti-huntingtin (htt) antibodies and uses thereof |
| EP3191578B1 (de) * | 2014-09-12 | 2020-11-04 | Whitehead Institute for Biomedical Research | Zellen zur expression von apolipoprotein e und verwendungen davon |
| WO2016081371A1 (en) | 2014-11-17 | 2016-05-26 | The Board Of Trustees Of The Leland Stanford Junior University | Noscapinoid-producing microbes and methods of making and using the same |
| EP3292203A4 (de) | 2015-05-04 | 2019-10-09 | The Board of Trustees of the Leland Stanford Junior University | Benzylisochinolin-alkaloid (bia)-vorläufer produzierende mikroben sowie verfahren zur herstellung und verwendung davon |
| JP7266966B2 (ja) | 2015-05-08 | 2023-05-01 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | エピメラーゼ及びベンジルイソキノリンアルカロイドを産生する方法 |
| US11674952B2 (en) | 2016-02-24 | 2023-06-13 | The Rockefeller University | Embryonic cell-based therapeutic candidate screening systems, models for Huntington's Disease and uses thereof |
| EP3566055B1 (de) | 2017-01-06 | 2025-03-12 | Janssen Pharmaceutica NV | Scd-hemmer zur behandlung von neurologischen erkrankungen |
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| US10550550B2 (en) * | 2017-09-13 | 2020-02-04 | Dominic P. Ismert | Modular two-part sillcock |
| US20200255487A1 (en) * | 2017-10-12 | 2020-08-13 | The Regents Of The University Of California | A Cell-Based Seeding Assay for Huntingtin Aggregation |
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| CN120399912A (zh) | 2019-03-08 | 2025-08-01 | 小利兰·斯坦福大学托管委员会 | 产生莨菪烷生物碱(ta)的非植物宿主细胞及其制备和使用方法 |
| US12352719B2 (en) | 2019-09-20 | 2025-07-08 | KYCERA AVX Components Corporation | Somatic cell-based electrical biosensor |
| WO2023284782A1 (zh) * | 2021-07-14 | 2023-01-19 | 复旦大学 | 筛选用于治疗或预防mHTT相关的神经退行性疾病的化合物的方法,靶蛋白,以及化合物 |
| US20250093332A1 (en) * | 2022-01-12 | 2025-03-20 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods and related aspects of quantifying protein stability and misfolding |
| CN114990049B (zh) * | 2022-04-26 | 2024-01-16 | 鼎康(武汉)生物医药有限公司 | 一种同时调节细胞表达产物的糖型和电荷异质性的方法 |
| EP4594342A2 (de) | 2022-09-29 | 2025-08-06 | Antheia, Inc. | Verfahren zur verbesserung der produktion von morphinan-alkaloiden und derivaten |
| DE202022107272U1 (de) | 2022-12-28 | 2023-01-30 | Centurion University of Technology and Management | Ein System zur Analyse der Infektion mit Pseudomonas Syringae durch gezielte Ansprache von Cochaperonen, die eine J-Domäne enthalten |
| WO2024172061A1 (ja) * | 2023-02-17 | 2024-08-22 | 国立大学法人京都大学 | Rnaアプタマー |
| GB202315164D0 (en) | 2023-10-03 | 2023-11-15 | Univ Edinburgh | Nanochromosome |
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| IT1317922B1 (it) | 2000-10-24 | 2003-07-15 | S I S S A Scuola Internaz Supe | Metodo per identificare in vivo epitopi intracellulari. |
| US7045290B2 (en) * | 2001-02-15 | 2006-05-16 | The University Of Chicago | Yeast screens for treatment of human disease |
| GB0104685D0 (en) * | 2001-02-26 | 2001-04-11 | Leuven K U Res & Dev | Tau-opathy model |
| AU2002310497A1 (en) * | 2001-06-20 | 2003-01-08 | Caprion Pharmaceuticals Inc. | Protein aggregation assays and uses thereof |
| US20060008894A1 (en) | 2003-07-11 | 2006-01-12 | Gerard Griffioen | Yeast model for amyloidogenic protein toxicity |
-
2002
- 2002-02-15 US US10/077,584 patent/US7045290B2/en not_active Expired - Lifetime
- 2002-02-15 EP EP02718994A patent/EP1392849B2/de not_active Expired - Lifetime
- 2002-02-15 EP EP10180773A patent/EP2319936A3/de not_active Withdrawn
- 2002-02-15 AT AT02718994T patent/ATE382704T1/de not_active IP Right Cessation
- 2002-02-15 AT AT06024213T patent/ATE532874T1/de active
- 2002-02-15 DE DE60224383T patent/DE60224383T3/de not_active Expired - Lifetime
- 2002-02-15 JP JP2002564603A patent/JP4344138B2/ja not_active Expired - Lifetime
- 2002-02-15 WO PCT/US2002/004632 patent/WO2002065136A2/en not_active Ceased
- 2002-02-15 CA CA2438661A patent/CA2438661C/en not_active Expired - Lifetime
- 2002-02-15 AU AU2002250102A patent/AU2002250102B2/en not_active Expired
-
2006
- 2006-02-27 US US11/363,869 patent/US20060147902A1/en not_active Abandoned
- 2006-02-27 US US11/363,870 patent/US8039209B2/en not_active Expired - Fee Related
-
2007
- 2007-10-10 AU AU2007221933A patent/AU2007221933B2/en not_active Ceased
-
2008
- 2008-04-17 JP JP2008108214A patent/JP5152977B2/ja not_active Expired - Lifetime
-
2011
- 2011-02-22 AU AU2011200744A patent/AU2011200744B2/en not_active Expired
- 2011-04-20 US US13/090,653 patent/US20110300533A1/en not_active Abandoned
-
2012
- 2012-05-02 US US13/462,478 patent/US20130005608A1/en not_active Abandoned
-
2013
- 2013-12-13 US US14/105,500 patent/US9518284B2/en not_active Expired - Fee Related
-
2016
- 2016-11-08 US US15/345,739 patent/US20170306386A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US20130005608A1 (en) | 2013-01-03 |
| EP1392849B2 (de) | 2012-01-18 |
| EP2319936A2 (de) | 2011-05-11 |
| US20060147902A1 (en) | 2006-07-06 |
| EP1392849B1 (de) | 2008-01-02 |
| JP5152977B2 (ja) | 2013-02-27 |
| CA2438661C (en) | 2011-05-31 |
| DE60224383T2 (de) | 2009-01-08 |
| AU2007221933B2 (en) | 2010-12-16 |
| JP4344138B2 (ja) | 2009-10-14 |
| WO2002065136A3 (en) | 2003-12-11 |
| AU2002250102B2 (en) | 2007-07-12 |
| US20030073610A1 (en) | 2003-04-17 |
| US20140273074A1 (en) | 2014-09-18 |
| US20060141449A1 (en) | 2006-06-29 |
| AU2007221933A1 (en) | 2007-11-01 |
| EP2319936A3 (de) | 2012-10-17 |
| JP2004537973A (ja) | 2004-12-24 |
| US7045290B2 (en) | 2006-05-16 |
| US20170306386A1 (en) | 2017-10-26 |
| DE60224383D1 (de) | 2008-02-14 |
| JP2008259509A (ja) | 2008-10-30 |
| US20110300533A1 (en) | 2011-12-08 |
| US9518284B2 (en) | 2016-12-13 |
| US8039209B2 (en) | 2011-10-18 |
| AU2011200744A1 (en) | 2011-03-17 |
| DE60224383T3 (de) | 2012-06-28 |
| ATE382704T1 (de) | 2008-01-15 |
| EP1392849A2 (de) | 2004-03-03 |
| AU2011200744B2 (en) | 2013-04-04 |
| CA2438661A1 (en) | 2002-08-22 |
| WO2002065136A2 (en) | 2002-08-22 |
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