ATE535231T1 - Verfahren zur herstellung von poly-iclc und seine verwendung - Google Patents
Verfahren zur herstellung von poly-iclc und seine verwendungInfo
- Publication number
- ATE535231T1 ATE535231T1 AT03819324T AT03819324T ATE535231T1 AT E535231 T1 ATE535231 T1 AT E535231T1 AT 03819324 T AT03819324 T AT 03819324T AT 03819324 T AT03819324 T AT 03819324T AT E535231 T1 ATE535231 T1 AT E535231T1
- Authority
- AT
- Austria
- Prior art keywords
- iclc
- poly
- producing poly
- neoplastic
- effective dose
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39371302P | 2002-07-03 | 2002-07-03 | |
| PCT/US2003/020828 WO2005102278A1 (en) | 2002-07-03 | 2003-07-01 | Method for preparation of poly-iclc and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE535231T1 true ATE535231T1 (de) | 2011-12-15 |
Family
ID=35196710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03819324T ATE535231T1 (de) | 2002-07-03 | 2003-07-01 | Verfahren zur herstellung von poly-iclc und seine verwendung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7439349B2 (de) |
| EP (1) | EP1778186B1 (de) |
| AT (1) | ATE535231T1 (de) |
| AU (1) | AU2003248791A1 (de) |
| ES (1) | ES2378150T3 (de) |
| WO (1) | WO2005102278A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1838338A2 (de) * | 2004-12-29 | 2007-10-03 | Mannkind Corporation | Verfahren zum auslösen, erhalten und manipulieren von immunantworten durch gezielte verabreichung von biologischen response-modifikatoren in lymphoiden organen |
| EP1723971A1 (de) * | 2005-05-20 | 2006-11-22 | Immunoclin Limited | Methoden und Zusammensetzungen zur Behandlung von viralen Erkrankungen |
| JP5373616B2 (ja) * | 2006-11-03 | 2013-12-18 | ハー マジェスティー ザ クイーン, イン ライト オブ カナダ, アズ リプレゼンティッド バイ ザ ミニスター オブ ナショナル ディフェンス | 鳥インフルエンザウイルス感染の予防的治療のためのポリiclcカプセル化リポソーム |
| CA2680060A1 (en) * | 2007-03-07 | 2008-09-12 | Nventa Biopharmaceuticals Corporation | Double-stranded locked nucleic acid compositions |
| US20090088401A1 (en) * | 2007-09-27 | 2009-04-02 | Andres Salazar | In-situ cancer autovaccination with intratumoral stabilized dsRNA viral mimic |
| EP2275085A1 (de) * | 2009-07-07 | 2011-01-19 | University of Rostock | Biologisch abbaubares Copolymer zur Freisetzung von Nukleinsäurematerial in Zellen |
| US8569255B2 (en) | 2011-02-02 | 2013-10-29 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence | Post-exposure therapy of influenza A infections |
| EP2744502B1 (de) * | 2011-08-17 | 2016-03-30 | Oregon Health & Science University | Verfahren zur prävention von hypoxischen läsionen |
| CN105555303A (zh) | 2013-06-28 | 2016-05-04 | 贝勒研究院 | 用于多发性硬化症的树突细胞asgpr靶向免疫治疗剂 |
| AU2014315124A1 (en) * | 2013-09-06 | 2016-04-07 | Altimmune Inc. | Methods and compositions for viral vectored vaccines |
| EP3319587B1 (de) | 2015-11-17 | 2019-08-21 | Bioncotech Therapeutics, S.L | Neuartige pharmazeutische zusammensetzung umfassend partikel umfassend einen komplex eines doppelsträngigen polyribonucleotids und eines polyalkylenimins |
| US10849921B2 (en) | 2017-05-17 | 2020-12-01 | Bioncotech Therapeutics Sl | Pharmaceutical composition comprising particles comprising a complex of a double-stranded polyribonucleotide and a polyalkyleneimine |
| WO2021003365A1 (en) | 2019-07-03 | 2021-01-07 | Aim Immunotech Inc. | Compositions and methods useful for ebola virus infection |
| NL2030835B1 (en) | 2020-01-24 | 2022-12-29 | Aim Immunotech Inc | Methods, compositions, and vaccinces for treating a virus infection |
| WO2022061309A1 (en) | 2020-09-21 | 2022-03-24 | Aim Immunotech Inc. | Compositions and methods for treating cancer |
| WO2022235984A1 (en) | 2021-05-05 | 2022-11-10 | Aim Immunotech Inc. | Methods and compositions for treating neuroinflammation |
| WO2022271199A1 (en) * | 2021-06-21 | 2022-12-29 | Oncovir, Inc. | Method for prophylaxis and attenuation of covid-19 and other inflammatory microbial acute respiratory disease syndromes through modulation of innate and adaptive immunity with poly- iclc |
| UY39877A (es) * | 2021-07-30 | 2023-02-28 | Esteban Celis | Actividad biológica multidimensional optimizada de poli-iclc con tamaño y formulación de componentes |
| NL2032813B1 (en) | 2021-08-20 | 2024-12-09 | Aim Immunotech Inc | Compositions and methods for treating post-covid conditions of fatigue |
| WO2023049904A1 (en) | 2021-09-24 | 2023-03-30 | Aim Immunotech Inc. | Compositions and methods for enhancing and expanding infection induced immunity |
| CN120789234B (zh) * | 2025-07-21 | 2026-04-14 | 神州智康(北京)生物科技有限公司 | 一种增强细胞免疫的复合佐剂及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1364987A (en) * | 1971-06-19 | 1974-08-29 | Merck Patent Gmbh | Biologically active two component complexes |
| US4024241A (en) * | 1974-09-27 | 1977-05-17 | The United States Of America As Represented By The Secretary Of Health, Education And Welfare | Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
| US4349538A (en) * | 1979-12-07 | 1982-09-14 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Nuclease-resistant hydrophilic complex of polyriboinosinic-polyribocytidylic acid |
| US4388306A (en) * | 1980-06-04 | 1983-06-14 | Merck & Co., Inc. | Pharmaceutical composition comprising modified polyriboinosinic-polyribocytidylic acid, for induction of interferon in primates |
| US4389395A (en) * | 1981-01-09 | 1983-06-21 | Lerner A Martin | Low molecular weight complex of polyriboinosinic-polyribocytidylic acid and method of inducing interferon |
| JPS5993097A (ja) * | 1982-11-16 | 1984-05-29 | Yamasa Shoyu Co Ltd | ポリヌクレオチド複合体 |
| CA2203843C (en) * | 1997-04-28 | 2013-07-23 | Her Majesty The Queen, In Right Of Canada, As Represented By The Ministe R Of National Defence | Liposome-encapsulated poly iclc |
| AT410173B (de) * | 2000-06-08 | 2003-02-25 | Cistem Biotechnologies Gmbh | Antigene zusammensetzung |
-
2003
- 2003-07-01 AU AU2003248791A patent/AU2003248791A1/en not_active Abandoned
- 2003-07-01 EP EP03819324A patent/EP1778186B1/de not_active Expired - Lifetime
- 2003-07-01 WO PCT/US2003/020828 patent/WO2005102278A1/en not_active Ceased
- 2003-07-01 US US10/611,614 patent/US7439349B2/en not_active Expired - Lifetime
- 2003-07-01 AT AT03819324T patent/ATE535231T1/de active
- 2003-07-01 ES ES03819324T patent/ES2378150T3/es not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2378150T3 (es) | 2012-04-09 |
| AU2003248791A1 (en) | 2005-11-09 |
| EP1778186B1 (de) | 2011-11-30 |
| EP1778186A4 (de) | 2007-05-09 |
| EP1778186A1 (de) | 2007-05-02 |
| WO2005102278A1 (en) | 2005-11-03 |
| US7439349B2 (en) | 2008-10-21 |
| US20040005998A1 (en) | 2004-01-08 |
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