ATE535240T1 - Nahrungs- oder therapeutische zusammensetzung, enthaltend oleuropein oder seine derivate - Google Patents

Nahrungs- oder therapeutische zusammensetzung, enthaltend oleuropein oder seine derivate

Info

Publication number: ATE535240T1
Authority: AT; Austria
Prior art keywords: bone; derivatives; animals; stimulating; formation
Prior art date: 2003-04-11

Application number

AT04742843T

Other languages

English (en)

Inventor

Veronique Coxam

Leandros Skaltsounis

Caroline Puel

Andre Mazur

Original Assignee

Agronomique Inst Nat Rech

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-04-11

Filing date

2004-04-09

Publication date

2011-12-15

2004-04-09 Application filed by Agronomique Inst Nat Rech filed Critical Agronomique Inst Nat Rech

2011-12-15 Application granted granted Critical

2011-12-15 Publication of ATE535240T1 publication Critical patent/ATE535240T1/de

Links

239000000203 mixture Substances 0.000 title abstract 3
RFWGABANNQMHMZ-UHFFFAOYSA-N 8-acetoxy-7-acetyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxolo[4',5':4,5]benzo[1,2,3-de]quinoline Natural products CC=C1C(CC(=O)OCCC=2C=C(O)C(O)=CC=2)C(C(=O)OC)=COC1OC1OC(CO)C(O)C(O)C1O RFWGABANNQMHMZ-UHFFFAOYSA-N 0.000 title abstract 2
HKVGJQVJNQRJPO-UHFFFAOYSA-N Demethyloleuropein Natural products O1C=C(C(O)=O)C(CC(=O)OCCC=2C=C(O)C(O)=CC=2)C(=CC)C1OC1OC(CO)C(O)C(O)C1O HKVGJQVJNQRJPO-UHFFFAOYSA-N 0.000 title abstract 2
RFWGABANNQMHMZ-HYYSZPHDSA-N Oleuropein Chemical compound O([C@@H]1OC=C([C@H](C1=CC)CC(=O)OCCC=1C=C(O)C(O)=CC=1)C(=O)OC)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RFWGABANNQMHMZ-HYYSZPHDSA-N 0.000 title abstract 2
RFWGABANNQMHMZ-CARRXEGNSA-N oleuropein Natural products COC(=O)C1=CO[C@@H](O[C@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2O)C(=CC)[C@H]1CC(=O)OCCc3ccc(O)c(O)c3 RFWGABANNQMHMZ-CARRXEGNSA-N 0.000 title abstract 2
235000011576 oleuropein Nutrition 0.000 title abstract 2
235000005911 diet Nutrition 0.000 title 1
230000000378 dietary effect Effects 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
210000000988 bone and bone Anatomy 0.000 abstract 6
241001465754 Metazoa Species 0.000 abstract 3
230000015572 biosynthetic process Effects 0.000 abstract 3
230000004936 stimulating effect Effects 0.000 abstract 3
206010061218 Inflammation Diseases 0.000 abstract 2
230000004054 inflammatory process Effects 0.000 abstract 2
230000002401 inhibitory effect Effects 0.000 abstract 2
102000012404 Orosomucoid Human genes 0.000 abstract 1
108010061952 Orosomucoid Proteins 0.000 abstract 1
208000001132 Osteoporosis Diseases 0.000 abstract 1
244000133018 Panax trifolius Species 0.000 abstract 1
235000019483 Peanut oil Nutrition 0.000 abstract 1
235000019484 Rapeseed oil Nutrition 0.000 abstract 1
241000700159 Rattus Species 0.000 abstract 1
206010041660 Splenomegaly Diseases 0.000 abstract 1
239000004480 active ingredient Substances 0.000 abstract 1
230000002456 anti-arthritic effect Effects 0.000 abstract 1
230000000844 anti-bacterial effect Effects 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
229940121375 antifungal agent Drugs 0.000 abstract 1
239000003963 antioxidant agent Substances 0.000 abstract 1
230000003078 antioxidant effect Effects 0.000 abstract 1
230000033558 biomineral tissue development Effects 0.000 abstract 1
230000001054 cortical effect Effects 0.000 abstract 1
239000000824 cytostatic agent Substances 0.000 abstract 1
230000001085 cytostatic effect Effects 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
239000010462 extra virgin olive oil Substances 0.000 abstract 1
235000021010 extra-virgin olive oil Nutrition 0.000 abstract 1
230000002757 inflammatory effect Effects 0.000 abstract 1
229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
239000003550 marker Substances 0.000 abstract 1
230000010534 mechanism of action Effects 0.000 abstract 1
239000011707 mineral Substances 0.000 abstract 1
235000016709 nutrition Nutrition 0.000 abstract 1
210000001672 ovary Anatomy 0.000 abstract 1
239000002504 physiological saline solution Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
238000010254 subcutaneous injection Methods 0.000 abstract 1
239000007929 subcutaneous injection Substances 0.000 abstract 1
239000000454 talc Substances 0.000 abstract 1
229910052623 talc Inorganic materials 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Nutrition Science (AREA)
Molecular Biology (AREA)
Polymers & Plastics (AREA)
Food Science & Technology (AREA)
Mycology (AREA)
Botany (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Orthopedic Medicine & Surgery (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

AT04742843T 2003-04-11 2004-04-09 Nahrungs- oder therapeutische zusammensetzung, enthaltend oleuropein oder seine derivate ATE535240T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0304584A FR2853549B1 (fr)	2003-04-11	2003-04-11	Composition nutritionnelle ou therapeutique contenant le compose oleuropeine ou l'un de ses derives
PCT/FR2004/050156 WO2004091591A2 (fr)	2003-04-11	2004-04-09	Composition nutritionnelle ou therapeutique contenant le compose oleurofeine ou l'un de ses derives

Publications (1)

Publication Number	Publication Date
ATE535240T1 true ATE535240T1 (de)	2011-12-15

Family

ID=33041820

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT04742843T ATE535240T1 (de)	2003-04-11	2004-04-09	Nahrungs- oder therapeutische zusammensetzung, enthaltend oleuropein oder seine derivate

Country Status (9)

Country	Link
US (1)	US8138224B2 (de)
EP (1)	EP1617836B1 (de)
AT (1)	ATE535240T1 (de)
CA (1)	CA2521967C (de)
DK (1)	DK1617836T3 (de)
ES (1)	ES2378154T3 (de)
FR (1)	FR2853549B1 (de)
PL (1)	PL1617836T3 (de)
WO (1)	WO2004091591A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2274721B1 (es) *	2005-11-03	2008-06-01	Laboratorios Belmac, S.A.	Nuevo agente terapeutico para el tratamiento de una condicion asociada a la enfermedad vascular periferica.
CN101646433B (zh) *	2006-10-24	2011-11-16	戴维·W·克雷姆平	抗再吸收的和造骨的食物增补剂和使用方法
EP1982707A1 (de) *	2007-04-18	2008-10-22	DSMIP Assets B.V.	Verwendung von Hydroxytyrosol als Mittel gegen des Altern
JP2009227616A (ja) *	2008-03-24	2009-10-08	Toin Gakuen	オレウロペイン及び／又はヒドロキシチロソールを有効成分として含有する骨形成促進剤
GB0807673D0 (en) *	2008-04-28	2008-06-04	Bio Actor Bcba	Polyphenolic extract
ITMI20082122A1 (it) *	2008-11-28	2010-05-29	New Life Hold S R L	Nuova miscela per panificazione
US7897184B1 (en)	2009-08-13	2011-03-01	Access Business Group International Llc	Topical composition with skin lightening effect
WO2012060884A1 (en) *	2010-11-04	2012-05-10	Nestec S.A.	Methods and compositions for preventing and treating osteoarthritis
JP2016520544A (ja) *	2013-04-05	2016-07-14	ネステクソシエテアノニム	骨成長の刺激における使用のための組成物
CN113101297A (zh) *	2013-05-29	2021-07-13	雀巢产品有限公司	用于软骨破坏的组合物
WO2015055468A1 (en) *	2013-10-14	2015-04-23	Nestec S.A.	Anti-inflammatory phytonutrients for use in the treatment or prevention of synovitis
ITUB20150541A1 (it)	2015-03-03	2016-09-03	Acraf	Composizione comprendente sostanze e/o estratti naturali
ITUA20163791A1 (it) *	2016-05-25	2017-11-25	Alfonso Colacchio	Composto nutraceutico per il potenziamento del sistema immunitario ed il benessere delle ossa
CN106804629B (zh) *	2017-01-17	2020-07-17	长江大学	对节白蜡中具有杀菌活性的提取物及其杀菌组合物
JP7304346B2 (ja) *	2017-11-08	2023-07-06	ソシエテ・デ・プロデュイ・ネスレ・エス・アー	ホモバニリルアルコール（ｈｖａ）、ｈｖａ異性体、このような化合物を含む組成物の作製方法、及びこのような化合物を使用する方法
JP2022533036A (ja) *	2019-05-13	2022-07-21	ソシエテ・デ・プロデュイ・ネスレ・エス・アー	化合物オレウロペイン又はその代謝産物を使用して代謝疲労を治療又は予防する組成物及び方法
CA3140227A1 (en) *	2019-05-13	2020-11-19	Societe Des Produits Nestle S.A.	Compositions and methods using a combination of calcium and at least one of oleuropein or metabolite thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4761406A (en)	1985-06-06	1988-08-02	The Procter & Gamble Company	Regimen for treating osteoporosis
WO1996014064A1 (en) *	1994-11-07	1996-05-17	Strecker, Robert, B.	Method and composition for antiviral therapy
US5714150A (en) *	1997-01-08	1998-02-03	Nachman; Leslie	Method for producing extract of olive leaves
US20010046977A1 (en) *	1997-11-25	2001-11-29	Merck & Co., Inc.	Use of alendronate for the prevention of osteoporosis
US6117476A (en) *	1999-01-04	2000-09-12	Shaul Eger	Healthy food spreads
ES2157178B1 (es) *	1999-12-23	2002-02-16	Asac Compania De Biotecnologia	Procedimiento de obtencion de extractos de olea europaea y aplicaciones de los mismos.
US6437004B1 (en) *	2000-04-06	2002-08-20	Nicholas V. Perricone	Treatment of skin damage using olive oil polyphenols
AU5311301A (en) *	2000-04-20	2001-11-07	Upjohn Co	Use of thioamide oxazolidinones for the treatment of bone resorption and osteoporosis
US6440465B1 (en) *	2000-05-01	2002-08-27	Bioderm, Inc.	Topical composition for the treatment of psoriasis and related skin disorders
JP2002128678A (ja) *	2000-10-17	2002-05-09	Tama Seikagaku Kk	オレウロペインを含有する抽出組成物の製造方法
US6455070B1 (en) *	2001-02-15	2002-09-24	East Park Research, Inc.	Composition for treating symptoms of influenza
PT1397105E (pt) *	2001-05-23	2006-12-29	Hamdi K Hamdi	Composições para inibir angiogénese
CN1646093A (zh) *	2002-02-13	2005-07-27	克雷农业公司	治疗炎症和与aids关联的神经紊乱的方法和组合物
US7445807B2 (en) *	2002-10-15	2008-11-04	Western Holdings, Llc	Agglomerated granular protein-rich nutritional supplement

2003
- 2003-04-11 FR FR0304584A patent/FR2853549B1/fr not_active Expired - Fee Related
2004
- 2004-04-09 US US10/552,723 patent/US8138224B2/en not_active Expired - Fee Related
- 2004-04-09 PL PL04742843T patent/PL1617836T3/pl unknown
- 2004-04-09 CA CA2521967A patent/CA2521967C/fr not_active Expired - Lifetime
- 2004-04-09 AT AT04742843T patent/ATE535240T1/de active
- 2004-04-09 WO PCT/FR2004/050156 patent/WO2004091591A2/fr not_active Ceased
- 2004-04-09 EP EP04742843A patent/EP1617836B1/de not_active Expired - Lifetime
- 2004-04-09 DK DK04742843.8T patent/DK1617836T3/da active
- 2004-04-09 ES ES04742843T patent/ES2378154T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
FR2853549A1 (fr)	2004-10-15
EP1617836B1 (de)	2011-11-30
EP1617836A2 (de)	2006-01-25
ES2378154T3 (es)	2012-04-09
US20060193931A1 (en)	2006-08-31
CA2521967A1 (fr)	2004-10-28
US8138224B2 (en)	2012-03-20
WO2004091591A3 (fr)	2004-11-25
WO2004091591A2 (fr)	2004-10-28
PL1617836T3 (pl)	2012-05-31
DK1617836T3 (da)	2012-03-19
FR2853549B1 (fr)	2007-11-09
CA2521967C (fr)	2012-08-21

Publication	Publication Date	Title
ATE535240T1 (de)	2011-12-15	Nahrungs- oder therapeutische zusammensetzung, enthaltend oleuropein oder seine derivate
El-Kamali	2000	Folk medicinal use of some animal products in Central Sudan
ECSP055680A (es)	2005-05-30	Nuevos compuestos de imidazol como inhibidores del factor de crecimiento transformante (tgf)
ECSP055681A (es)	2005-05-30	Nuevos compuestos de triazol como inhibidores del factor de crecimiento transformante (tgf)
RU95113347A (ru)	1997-06-10	Спиропиперидины и их гомологи, способ получения, способ повышения уровней эндогенного гормона роста, способ лечения остеопороза, фармацевтическая композиция
BR0116001A (pt)	2004-07-06	Métodos para tratar distúrbios neuropsiquiátricos com antagonistas receptores nmda
IL192557A (en)	2013-09-30	Imidazole derivatives are conserved and used as ptpase inhibitors
ECSP055679A (es)	2005-05-30	Derivados de pirazol como inhibidores del factor del crecimiento transformante (tgf)
BRPI0515446A (pt)	2008-07-29	amidas bicìclicas como inibidores de cinases
ATE432072T1 (de)	2009-06-15	Verwendung von adapalen zur behandlung dermatologischer erkrankungen
BR0013879A (pt)	2002-05-07	Melhoria da condição de saúde de animais de estimação de idade avançada
BRPI0512274A (pt)	2008-02-19	derivados de piperazina aril-substituìdos
AR010700A1 (es)	2000-06-28	Derivados de purina sustituidos, procedimiento para su preparacion, su empleo y su agente que los contiene
BR0214902A (pt)	2004-11-30	Preparação bacteriana, frações de preparação bacteriana, composição farmacêutica, uso da preparação bacteriana ou suas frações, método para a produção da preparação de bactérias mortas liofilizadas estendidas, kit para o tratamento de uma doença compreendendo uma desregulação imune, e, produtos
ATE289293T1 (de)	2005-03-15	Substituierte aminoalkylamid-derivate als antagonisten des follikel-stimulierenden hormons
DE60315842D1 (de)	2007-10-04	Verwendung von hesperidin oder einem seiner derivate zur herstellung eines medikaments für die stimulierung der knochenbildung
DE60018409D1 (de)	2005-04-07	Verwendung von antiseptika zur herstelllung von arzneimitteln zur prophylaxe und behandlung von infektionen und/ oder funktionellen gewebeumformungen im körperinneren
ATE253904T1 (de)	2003-11-15	Verwendung von pharmazeutische zusammensetzungen enthaltend thymol und/oder carvacrol in der behandlung von histomoniasis
BRPI0413083A (pt)	2006-10-03	métodos para tratar inflamação e doenças associadas com inflamação com uma estatina e éter
BR9913337A (pt)	2001-05-15	Derivados tan-1057
BR0210401A (pt)	2004-08-17	Composto, composição farmacêutica, uso de um composto e método para o tratamento de um distúrbio ou de uma doença de um corpo de animal vivo, incluindo um humano
Naser et al.	2014	Central depressant effects and toxicity of propofol in chicks
Gilotra et al.	2012	Capacitive coupling reduces instrumentation-related infection in rabbit spines: a pilot study
Rickert et al.	2021	Growth modulation by stimulating the growth plate: a pilot study
Lambertz et al.	2008	Influence of a chronic myositis on rat spinal field potentials evoked by TTX-resistant unmyelinated skin and muscle afferents