ATE535609T1 - Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon - Google Patents

Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon

Info

Publication number
ATE535609T1
ATE535609T1 AT06750625T AT06750625T ATE535609T1 AT E535609 T1 ATE535609 T1 AT E535609T1 AT 06750625 T AT06750625 T AT 06750625T AT 06750625 T AT06750625 T AT 06750625T AT E535609 T1 ATE535609 T1 AT E535609T1
Authority
AT
Austria
Prior art keywords
protected
amino
substituted butane
epoxy
present
Prior art date
Application number
AT06750625T
Other languages
English (en)
Inventor
Nigel Bowers
Paul Skonezny
Gregory Stein
Thomas Franceschini
Shu-Jen Chiang
Wendy Anderson
Li You
Zizhuo Xing
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE535609T1 publication Critical patent/ATE535609T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06750625T 2005-05-25 2006-04-19 Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon ATE535609T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68430005P 2005-05-25 2005-05-25
US11/365,275 US7582468B2 (en) 2005-05-25 2006-03-01 Process for preparing (2R,3S)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof
PCT/US2006/014629 WO2006127180A1 (en) 2005-05-25 2006-04-19 A process for preparing (2r,3s)-1,2-epoxy-3-(protected)amino-4-substituted butane and intermediates thereof

Publications (1)

Publication Number Publication Date
ATE535609T1 true ATE535609T1 (de) 2011-12-15

Family

ID=36830991

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06750625T ATE535609T1 (de) 2005-05-25 2006-04-19 Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon

Country Status (6)

Country Link
US (2) US7582468B2 (de)
EP (1) EP1893765B1 (de)
AT (1) ATE535609T1 (de)
ES (1) ES2376345T3 (de)
TW (1) TW200716757A (de)
WO (1) WO2006127180A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0619240D0 (en) * 2006-09-29 2006-11-08 Almac Sciences Ltd Reduction of alpha-halo ketones
CN101778624A (zh) * 2007-06-22 2010-07-14 百时美施贵宝公司 含有阿扎那韦的压片组合物
MX2009013499A (es) * 2007-06-22 2010-01-18 Bristol Myers Squibb Co Composiciones comprimidas que contienen atazanavir.
DE602008005316D1 (de) * 2007-06-22 2011-04-14 Bristol Myers Squibb Co Tablettierte atazanavirhaltige zusammensetzungen
JP2010530892A (ja) * 2007-06-22 2010-09-16 ブリストル−マイヤーズ スクイブ カンパニー アタザナビルを含む錠剤組成物
SG177331A1 (en) 2009-06-22 2012-02-28 Codexis Inc Ketoreductase-mediated stereoselective route to alpha chloroalcohols
WO2011100265A2 (en) 2010-02-10 2011-08-18 Codexis, Inc. Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
WO2014150633A1 (en) * 2013-03-15 2014-09-25 Merck Sharp & Dohme Corp. Immobilized ketoreductases and process for making and using immobilized ketoreductase
CN108558793A (zh) * 2018-06-01 2018-09-21 徐州诺克非医药科技有限公司 一种中间体环氧化氨基苯丁烷的合成方法
CN112892190B (zh) * 2021-01-27 2023-03-10 成都中科绿生环境科技有限公司 一种化学除臭剂及其制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2103932A1 (en) * 1992-11-05 1994-05-06 Ramesh N. Patel Stereoselective reduction of ketones
JP3529904B2 (ja) * 1995-06-19 2004-05-24 鐘淵化学工業株式会社 光学活性１−ハロ−３−アミノ−４−フェニル−２−ブタノール誘導体の製造法
US5849911A (en) * 1996-04-22 1998-12-15 Novartis Finance Corporation Antivirally active heterocyclic azahexane derivatives
ATE250024T1 (de) * 1999-01-21 2003-10-15 Kaneka Corp Methode zur reinigung und abtrennung von (2s,3s)- oder (2r,3s)-halohydrinderivaten
AU2322600A (en) * 1999-01-29 2000-08-18 Kaneka Corporation Processes for the preparation of (threo)-1,2-epoxy-3-amino-4-phenylbutane derivatives
US6605732B1 (en) * 1999-05-03 2003-08-12 Aerojet Fine Chemicals Llc Clean, high-yield preparation of S,S and R,S amino acid isosteres
KR100708221B1 (ko) * 1999-08-31 2007-04-17 아지노모토 가부시키가이샤 에폭사이드 결정의 제조방법
EP1309714B1 (de) * 2000-08-16 2009-05-13 Bristol-Myers Squibb Company Stereoselektive verminderung von substituierten oxo-butanen
US6764545B2 (en) * 2000-12-12 2004-07-20 Ajinomoto Co., Inc. Production method of epoxide crystal

Also Published As

Publication number Publication date
TW200716757A (en) 2007-05-01
US20090286303A1 (en) 2009-11-19
US8119389B2 (en) 2012-02-21
ES2376345T3 (es) 2012-03-13
EP1893765B1 (de) 2011-11-30
WO2006127180A1 (en) 2006-11-30
EP1893765A1 (de) 2008-03-05
US7582468B2 (en) 2009-09-01
US20060270012A1 (en) 2006-11-30

Similar Documents

Publication Publication Date Title
DE50302270D1 (de) Verfahren zur Herstellung von organischen Siliciumverbindungen
DE502005010443D1 (de) Verfahren zur herstellung von isocyanaten
TW200700403A (en) Process for preparing an epoxide from a polyhydroxylated aliphatic hydrocarbon and a chlorinating agent
ATE493392T1 (de) Verfahren zur rückgewinnung von propylenoxid
EA200970605A1 (ru) Ингибиторы mapk/erk-киназ
ATE535609T1 (de) Verfahren zur herstellung von (2r,3s)-1,2-epoxy-3-(geschütztes)amino-4-substi uiertem butan und zwischenstufen davon
ATE475664T1 (de) Verfahren zur herstellung poröser organischer gerüstmaterialien
FI20105583L (fi) Menetelmä ja laite hiilivetyjen tuottamiseksi
MY177112A (en) Process for preparing a chlorohydrin in corrosion-resistant apparatus
ATE463472T1 (de) Verfahren zur herstellung von olefinen
ATE514653T1 (de) Verfahren zur herstellung von trichlorsilan
ATE533794T1 (de) Katalysatorsystem und verfahren zur herstellung von polyethylen in gegenwart dieses katalysatorsystems
DE502005010811D1 (de) Verfahren zur reinigung und aufkonzentrierung von distickstoffmonoxid
ATE540068T1 (de) Verfahren zur kontinuierlichen herstellung von epoxidharzen
DE602006005898D1 (de) Verfahren zur herstellung von cyclohexanon und cyclohexanol
ATE523517T1 (de) Verfahren zur herstellung von aminoorganosilanen
ATE530590T1 (de) Verfahren zur herstellung von polyesterolen
IL180354A0 (en) Process for the preparation of atomoxetine hydrochloride
ATE497942T1 (de) Integriertes verfahren zur herstellung von benzol und ammoniak ausgehend von aliphatischen kohlenwasserstoffen und stickstoff
ATE473963T1 (de) Verfahren zur herstellung eines organischen hydroperoxids, industrielle einrichtung dafür und verfahren mittels verwendung eines derartigen hydroperoxids zur herstellung eines alkylenoxids
ATE537133T1 (de) Verfahren zur herstellung von olefin
ATE477245T1 (de) Verfahren zur herstellung von onium-salzen mit geringem chlorid-gehalt
WO2009013971A1 (ja) 炭化水素油の水素化精製方法
ATE417840T1 (de) Verfahren zur herstellung von alkylenoxid
EA201391427A1 (ru) Способ пуска реактора с суспензионным слоем типа барботажной колонны, растворитель для пуска и способ получения углеводородного масла