ATE53588T1 - Herstellung von cytosin-nukleosiden. - Google Patents

Herstellung von cytosin-nukleosiden.

Info

Publication number: ATE53588T1
Authority: AT; Austria
Prior art keywords: production; cytosine; hydroxy; cytosine nucleosides; protected
Prior art date: 1985-03-05

Application number

AT86102695T

Other languages

English (en)

Inventor

Mitsuru Kawada

Kiyoharu Matsumoto

Masaaki Tsurushima

Original Assignee

Takeda Chemical Industries Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-03-05

Filing date

1986-03-01

Publication date

1990-06-15

1986-03-01 Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd

1990-06-15 Application granted granted Critical

1990-06-15 Publication of ATE53588T1 publication Critical patent/ATE53588T1/de

Links

OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 title abstract 5
229940104302 cytosine Drugs 0.000 title abstract 3
239000002777 nucleoside Substances 0.000 title abstract 3
-1 cytosine nucleoside Chemical class 0.000 abstract 1
150000002772 monosaccharides Chemical class 0.000 abstract 1
150000003833 nucleoside derivatives Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Saccharide Compounds (AREA)

AT86102695T 1985-03-05 1986-03-01 Herstellung von cytosin-nukleosiden. ATE53588T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP60044219A JPS61204193A (ja)	1985-03-05	1985-03-05	シトシンヌクレオシド類の製造法
EP86102695A EP0193903B1 (de)	1985-03-05	1986-03-01	Herstellung von Cytosin-Nukleosiden

Publications (1)

Publication Number	Publication Date
ATE53588T1 true ATE53588T1 (de)	1990-06-15

Family

ID=12685429

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86102695T ATE53588T1 (de)	1985-03-05	1986-03-01	Herstellung von cytosin-nukleosiden.

Country Status (9)

Country	Link
US (1)	US4689404A (de)
EP (1)	EP0193903B1 (de)
JP (1)	JPS61204193A (de)
KR (1)	KR920004486B1 (de)
CN (1)	CN1012366B (de)
AT (1)	ATE53588T1 (de)
CA (1)	CA1262897A (de)
DE (1)	DE3671896D1 (de)
ES (1)	ES8707971A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS6393796A (ja) *	1986-10-09	1988-04-25	Shin Etsu Chem Co Ltd	ペプチド合成の脱保護基用薬剤
MY164523A (en) *	2000-05-23	2017-12-29	Univ Degli Studi Cagliari	Methods and compositions for treating hepatitis c virus
JP5230052B2 (ja) *	2000-05-26	2013-07-10	イデニクス（ケイマン）リミテツド	フラビウイルスおよびペスチウイルス治療のための方法および組成物
AP2005003213A0 (en) *	2002-06-28	2005-03-31	Univ Cagliari	2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections.
NZ537662A (en)	2002-06-28	2007-10-26	Idenix Cayman Ltd	2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections
US7608600B2 (en) *	2002-06-28	2009-10-27	Idenix Pharmaceuticals, Inc.	Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
US7824851B2 (en)	2002-11-15	2010-11-02	Idenix Pharmaceuticals, Inc.	2′-branched nucleosides and Flaviviridae mutation
MXPA05006230A (es)	2002-12-12	2005-09-20	Idenix Cayman Ltd	Proceso para la produccion de nucleosidos ramificados-2'.
US7595390B2 (en) *	2003-04-28	2009-09-29	Novartis Ag	Industrially scalable nucleoside synthesis
KR100588741B1 (ko) *	2003-05-23	2006-06-12	엘지전자 주식회사	세탁기의 자동 건조방법
EP1639121A4 (de) *	2003-06-30	2008-04-16	Idenix Cayman Ltd	Synthese von beta-l-2-desoxynukleosiden
ES2422290T3 (es)	2005-12-23	2013-09-10	Idenix Pharmaceuticals Inc	Procedimiento para preparar un producto intermedio sintético para la preparación de nucleósidos ramificados
CN104955458A (zh) *	2012-11-07	2015-09-30	Z·索	取代的吉西他滨芳基酰胺类似物和使用所述类似物的治疗方法
US10435429B2 (en)	2017-10-03	2019-10-08	Nucorion Pharmaceuticals, Inc.	5-fluorouridine monophosphate cyclic triester compounds
KR102708995B1 (ko)	2018-01-10	2024-09-23	누코리온 파마슈티컬스, 인코포레이티드.	포스포르(포스포론)아미다타세탈 및 포스프(온)아탈세탈 화합물
US11427550B2 (en)	2018-01-19	2022-08-30	Nucorion Pharmaceuticals, Inc.	5-fluorouracil compounds
AU2020315394A1 (en)	2019-07-17	2022-02-17	Nucorion Pharmaceuticals, Inc.	Cyclic deoxyribonucleotide compounds
EP4143199B1 (de)	2020-04-21	2025-11-19	Ligand Pharmaceuticals, Inc.	Nukleotid-prodrug-verbindungen
CN115768778A (zh)	2020-04-21	2023-03-07	配体药物公司	苄氧基磷酸(膦酸)酯化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3328388A (en) *	1964-09-02	1967-06-27	Merck & Co Inc	Arabinofuranosyl pyrimidines and methods of preparing same
US4211773A (en) *	1978-10-02	1980-07-08	Sloan Kettering Institute For Cancer Research	5-Substituted 1-(2'-Deoxy-2'-substituted-β-D-arabinofuranosyl)pyrimidine nucleosides
US4423212A (en) *	1980-12-18	1983-12-27	The Upjohn Company	Nucleosides and process

1985
- 1985-03-05 JP JP60044219A patent/JPS61204193A/ja active Pending
1986
- 1986-02-20 US US06/831,441 patent/US4689404A/en not_active Expired - Fee Related
- 1986-03-01 EP EP86102695A patent/EP0193903B1/de not_active Expired - Lifetime
- 1986-03-01 DE DE8686102695T patent/DE3671896D1/de not_active Expired - Fee Related
- 1986-03-01 AT AT86102695T patent/ATE53588T1/de active
- 1986-03-04 KR KR1019860001506A patent/KR920004486B1/ko not_active Expired
- 1986-03-04 CA CA000503231A patent/CA1262897A/en not_active Expired
- 1986-03-04 ES ES552620A patent/ES8707971A1/es not_active Expired
- 1986-03-05 CN CN86101400A patent/CN1012366B/zh not_active Expired

Also Published As

Publication number	Publication date
EP0193903B1 (de)	1990-06-13
ES552620A0 (es)	1987-09-01
EP0193903A2 (de)	1986-09-10
EP0193903A3 (en)	1988-01-07
ES8707971A1 (es)	1987-09-01
CN1012366B (zh)	1991-04-17
JPS61204193A (ja)	1986-09-10
CN86101400A (zh)	1986-09-10
US4689404A (en)	1987-08-25
DE3671896D1 (de)	1990-07-19
KR860007282A (ko)	1986-10-10
KR920004486B1 (ko)	1992-06-05
CA1262897A (en)	1989-11-14

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