ATE536178T1 - Therapeutische anwendung von methionin zur behandlung oder prävention von mucositis - Google Patents
Therapeutische anwendung von methionin zur behandlung oder prävention von mucositisInfo
- Publication number
- ATE536178T1 ATE536178T1 AT04810055T AT04810055T ATE536178T1 AT E536178 T1 ATE536178 T1 AT E536178T1 AT 04810055 T AT04810055 T AT 04810055T AT 04810055 T AT04810055 T AT 04810055T AT E536178 T1 ATE536178 T1 AT E536178T1
- Authority
- AT
- Austria
- Prior art keywords
- methionine
- mucositis
- treatment
- prevention
- therapeutic use
- Prior art date
Links
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 title abstract 2
- 206010028116 Mucosal inflammation Diseases 0.000 title abstract 2
- 201000010927 Mucositis Diseases 0.000 title abstract 2
- 229930182817 methionine Natural products 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 abstract 4
- 230000000259 anti-tumor effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052697 platinum Inorganic materials 0.000 abstract 2
- 206010073306 Exposure to radiation Diseases 0.000 abstract 1
- 239000003223 protective agent Substances 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/694,436 US20050090551A1 (en) | 2003-10-27 | 2003-10-27 | Therapeutic use of methionine for the treatment or prevention of mucositis |
| PCT/US2004/035626 WO2005039554A2 (en) | 2003-10-27 | 2004-10-27 | Therapeutic use of methionine for the treatment or prevention of mucositis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE536178T1 true ATE536178T1 (de) | 2011-12-15 |
Family
ID=34522601
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04810055T ATE536178T1 (de) | 2003-10-27 | 2004-10-27 | Therapeutische anwendung von methionin zur behandlung oder prävention von mucositis |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20050090551A1 (de) |
| EP (1) | EP1677775B1 (de) |
| JP (1) | JP4884974B2 (de) |
| AT (1) | ATE536178T1 (de) |
| AU (1) | AU2004283756B2 (de) |
| CA (1) | CA2543870C (de) |
| ES (1) | ES2376102T3 (de) |
| WO (1) | WO2005039554A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7071230B2 (en) * | 1997-10-02 | 2006-07-04 | Board Of Trustees Of Southern Illinois University | Therapeutic use of D-methionine to reduce the toxicity of noise |
| EP2001460A4 (de) * | 2006-03-28 | 2011-01-12 | Novus Int Inc | Zusammensetzungen zur förderung des haarwachstums |
| GB0704718D0 (en) * | 2007-03-12 | 2007-04-18 | Prendergast Patrick T | Compounds and methods for preventing and treating mucositis |
| WO2009094172A2 (en) * | 2008-01-22 | 2009-07-30 | Araim Pharmaceuticals, Inc. | Tissue protective peptides and peptide analogs for preventing and treating diseases and disorders associated with tissue damage |
| JP2011514349A (ja) | 2008-03-07 | 2011-05-06 | サイドース・エルエルシー | フルベストラント配合物 |
| US20120148509A1 (en) * | 2009-09-14 | 2012-06-14 | Shiseido Company, Ltd. | Composition for alleviating ultraviolet irradiation-induced damage |
| JP5703228B2 (ja) * | 2009-09-30 | 2015-04-15 | 株式会社 資生堂 | 紫外線障害軽減経口組成物 |
| US8541465B2 (en) | 2009-10-19 | 2013-09-24 | Scidose, Llc | Docetaxel formulations with lipoic acid and/or dihydrolipoic acid |
| US7772274B1 (en) | 2009-10-19 | 2010-08-10 | Scidose, Llc | Docetaxel formulations with lipoic acid |
| US8912228B2 (en) | 2009-10-19 | 2014-12-16 | Scidose Llc | Docetaxel formulations with lipoic acid |
| US8476310B2 (en) | 2009-10-19 | 2013-07-02 | Scidose Llc | Docetaxel formulations with lipoic acid |
| JP5578997B2 (ja) * | 2010-09-16 | 2014-08-27 | 国立大学法人 大分大学 | がん化学療法誘発脱毛に対する抗脱毛用組成物 |
| US11179468B2 (en) | 2012-04-09 | 2021-11-23 | Eagle Pharmaceuticals, Inc. | Fulvestrant formulations |
| WO2020036975A1 (en) * | 2018-08-14 | 2020-02-20 | Tosk, Inc. | Methods and compositions for reducing fluorouracil induced toxicity |
| US11446303B2 (en) | 2019-06-21 | 2022-09-20 | Tosk, Inc. | Uridine phosphorylase (UPase) inhibitors for treatment of liver conditions |
| WO2022010778A1 (en) | 2020-07-07 | 2022-01-13 | Tosk, Inc. | Uridine phosphorylase inhibitors to treat or prevent pulmonary disease |
| CN114051974B (zh) * | 2021-11-10 | 2023-01-17 | 广西医科大学 | 一种肝癌模型及其构建方法与应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3652290A (en) * | 1970-08-10 | 1972-03-28 | Merck & Co Inc | Beverages containing stabilized vitamin c |
| US3962429A (en) * | 1973-08-01 | 1976-06-08 | Chugai Seiyaku Kabushiki Kaisha | Method for reducing side effects of aminoglycoside antibiotics and composition therefor |
| US4961926A (en) * | 1987-11-19 | 1990-10-09 | Sloan-Kettering Institute For Cancer Research | Methods for prevention and treatment of mucositis with granulocyte colony stimulating factor |
| US5122369A (en) * | 1990-03-30 | 1992-06-16 | Harmony Health Products, Inc. | Nutrient composition for preventing hair loss |
| WO1996001101A1 (en) * | 1994-07-01 | 1996-01-18 | The Procter & Gamble Company | Desquamation compositions |
| JPH08190187A (ja) * | 1995-01-11 | 1996-07-23 | Canon Inc | 情報記録装置 |
| US5667791A (en) * | 1996-05-31 | 1997-09-16 | Thione International, Inc. | X-ray induced skin damage protective composition |
| EP0930877B1 (de) * | 1996-10-03 | 2006-04-19 | Southern Illinois University | D-methionin zur reduzierung der toxizität von platin-enthaltenden antitumor verbindungen |
| US6187817B1 (en) * | 1996-10-03 | 2001-02-13 | Southern Illinois University School Of Medicine | Therapeutic use of d-methionine to reduce the toxicity of platinum-containing anti-tumor compounds |
| ES2338946T3 (es) * | 1998-02-13 | 2010-05-13 | Nutramax Laboratories, Inc. | Agentes y procedimientos para la proteccion, tratamiento y reparacion del tejido conjuntivo. |
| EP1194161B1 (de) * | 1999-07-13 | 2005-11-23 | Biovitrum Ab | Zusammensetzungen mit stabilem faktor viii |
| ATE355087T1 (de) * | 2000-10-24 | 2006-03-15 | Cis Bio Int | Stabilisierung von radiopharmazeutischen zusammensetzungen mit einem hydrophilen thioether oder einem hydrophilen 6-hydroxy-chroman |
| JP4822652B2 (ja) * | 2000-11-22 | 2011-11-24 | エンド ファーマシューティカルズ インコーポレイテッド | 粘膜炎の治療 |
| BR0207948A (pt) * | 2001-03-09 | 2004-07-27 | Produits Nestel S A Soc D | Composição que melhora os déficits fisiológicos relacionados com a idade e que aumenta a longevidade |
| US20030157191A1 (en) * | 2001-11-29 | 2003-08-21 | Sound Pharmaceuticals Incorporated | Methods and compositions for ameliorating the undesirable effects of chemotherapy |
| WO2004080429A2 (en) * | 2003-03-13 | 2004-09-23 | Oregon Health & Science University | Use of thiol-based compositions in ameliorating mucosal injury |
| US20060058390A1 (en) * | 2004-09-14 | 2006-03-16 | Molecular Therapeutics, Inc. | D-methionine formulation with improved biopharmaceutical properties |
-
2003
- 2003-10-27 US US10/694,436 patent/US20050090551A1/en not_active Abandoned
-
2004
- 2004-10-27 AT AT04810055T patent/ATE536178T1/de active
- 2004-10-27 ES ES04810055T patent/ES2376102T3/es not_active Expired - Lifetime
- 2004-10-27 AU AU2004283756A patent/AU2004283756B2/en not_active Ceased
- 2004-10-27 EP EP04810055A patent/EP1677775B1/de not_active Expired - Lifetime
- 2004-10-27 JP JP2006538213A patent/JP4884974B2/ja not_active Expired - Fee Related
- 2004-10-27 WO PCT/US2004/035626 patent/WO2005039554A2/en not_active Ceased
- 2004-10-27 CA CA2543870A patent/CA2543870C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005039554A2 (en) | 2005-05-06 |
| JP2007509955A (ja) | 2007-04-19 |
| EP1677775B1 (de) | 2011-12-07 |
| JP4884974B2 (ja) | 2012-02-29 |
| CA2543870C (en) | 2013-03-12 |
| WO2005039554A3 (en) | 2005-12-15 |
| CA2543870A1 (en) | 2005-05-06 |
| AU2004283756A2 (en) | 2005-05-06 |
| AU2004283756B2 (en) | 2010-07-29 |
| EP1677775A2 (de) | 2006-07-12 |
| AU2004283756A1 (en) | 2005-05-06 |
| US20050090551A1 (en) | 2005-04-28 |
| ES2376102T3 (es) | 2012-03-09 |
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