ATE536552T1 - Kompetitven differential screening - Google Patents

Kompetitven differential screening

Info

Publication number
ATE536552T1
ATE536552T1 AT05810831T AT05810831T ATE536552T1 AT E536552 T1 ATE536552 T1 AT E536552T1 AT 05810831 T AT05810831 T AT 05810831T AT 05810831 T AT05810831 T AT 05810831T AT E536552 T1 ATE536552 T1 AT E536552T1
Authority
AT
Austria
Prior art keywords
binders
present
competitive
differential screening
provides methods
Prior art date
Application number
AT05810831T
Other languages
English (en)
Inventor
Anthony Day
David Estell
Paul Jedzejewski
Christopher Murray
Original Assignee
Danisco Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc filed Critical Danisco Us Inc
Application granted granted Critical
Publication of ATE536552T1 publication Critical patent/ATE536552T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05810831T 2004-10-15 2005-10-14 Kompetitven differential screening ATE536552T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61956204P 2004-10-15 2004-10-15
US63290804P 2004-12-03 2004-12-03
PCT/US2005/037004 WO2006044650A2 (en) 2004-10-15 2005-10-14 Competitive differential screening

Publications (1)

Publication Number Publication Date
ATE536552T1 true ATE536552T1 (de) 2011-12-15

Family

ID=36203551

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05810831T ATE536552T1 (de) 2004-10-15 2005-10-14 Kompetitven differential screening

Country Status (7)

Country Link
US (2) US20110098184A1 (de)
EP (1) EP1800136B1 (de)
JP (1) JP5255841B2 (de)
CN (1) CN101044405B (de)
AT (1) ATE536552T1 (de)
DK (1) DK1800136T3 (de)
WO (1) WO2006044650A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008292474A (ja) * 2007-04-27 2008-12-04 Nationa Hospital Organization 成人ｔ細胞白血病発症リスク判定方法
ES2678143T3 (es) 2010-01-19 2018-08-09 President And Fellows Of Harvard College Opsonina obtenida por ingeniería genética para la detección y el tratamiento de microorganismos patógenos
EP2734843A2 (de) 2011-07-18 2014-05-28 President and Fellows of Harvard College Manipulierte moleküle zur anzielung von mikroben und ihre verwendungen
JP6362543B2 (ja) 2012-02-23 2018-07-25 ジュノ セラピューティクス ゲーエムベーハー 細胞および他の複雑な生物学的材料のクロマトグラフィーによる単離
CN103012561B (zh) * 2012-12-26 2014-06-25 首都医科大学附属北京朝阳医院 一种肿瘤靶向诊断用小肽
EP2976642A4 (de) * 2013-03-15 2016-09-21 Harvard College Verfahren und zusammensetzungen zur verbesserung der erkennung und/oder aufnahme einer zieleinheit
US9988617B2 (en) 2013-05-21 2018-06-05 President And Fellows Of Harvard College Engineered heme-binding compositions and uses thereof
EP3546474B1 (de) 2013-12-18 2021-07-07 President and Fellows of Harvard College Crp-erfassung/-detektion von grampositiven bakterien
LT3132247T (lt) 2014-04-16 2021-12-10 Juno Therapeutics Gmbh Ląstelių populiacijos padauginimo būdai, rinkiniai ir priemonės
IL313845A (en) 2014-04-23 2024-08-01 Juno Therapeutics Inc Methods for enriching or producing immune cell populations for adoptive therapy
CN108289928B (zh) 2015-08-06 2024-09-17 哈佛大学校长及研究员协会 改进的微生物-结合分子和其用途
US11466253B2 (en) 2015-10-22 2022-10-11 Juno Therapeutics Gmbh Methods for culturing cells and kits and apparatus for same
HK1258932A1 (zh) 2015-10-22 2019-11-22 Juno Therapeutics Gmbh 用於转导的方法、反应剂盒、反应剂和设备
CN108474791B (zh) 2015-10-22 2022-07-08 朱诺治疗学有限公司 培养细胞的方法及用于该方法的试剂盒和设备
MA49288A (fr) 2017-04-27 2020-03-04 Juno Therapeutics Gmbh Reactifs particulaires oligomères et leurs méthodes d'utilisation
SG11202101204TA (en) 2018-08-09 2021-03-30 Juno Therapeutics Inc Processes for generating engineered cells and compositions thereof
EP3874024A1 (de) 2018-10-31 2021-09-08 Juno Therapeutics GmbH Verfahren zur selektion und stimulation von zellen und vorrichtung dafür

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4458066A (en) * 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4946778A (en) * 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5965132A (en) * 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
US5677136A (en) * 1994-11-14 1997-10-14 Systemix, Inc. Methods of obtaining compositions enriched for hematopoietic stem cells, compositions derived therefrom and methods of use thereof
GB9719176D0 (en) * 1997-09-09 1997-11-12 Glaxo Group Ltd New therapeutic method
AU4643300A (en) * 1999-04-12 2000-11-14 Regents Of The University Of California, The Engineering ecotin-variant modulators of serine proteases
WO2000061782A1 (en) * 1999-04-12 2000-10-19 The Regents Of The University Of California Ecotine derivatives
DE602004030212D1 (de) * 2003-01-16 2011-01-05 Caprotec Bioanalytics Gmbh Verfahren zur identifizierung von auf arzneimittel nicht-zielgerichteten proteinen
JP2006514299A (ja) * 2003-10-27 2006-04-27 センス プロテオミック リミテッド 酵素アレイ及びアッセイ
CA2544820C (en) * 2003-11-06 2014-02-18 Genencor International, Inc. Bacterial expression of protease inhibitors and variants thereof

Also Published As

Publication number Publication date
EP1800136B1 (de) 2011-12-07
JP5255841B2 (ja) 2013-08-07
WO2006044650A9 (en) 2006-08-31
CN101044405A (zh) 2007-09-26
DK1800136T3 (da) 2012-03-26
WO2006044650A3 (en) 2006-12-14
US20130029850A1 (en) 2013-01-31
JP2008517275A (ja) 2008-05-22
US20110098184A1 (en) 2011-04-28
WO2006044650A2 (en) 2006-04-27
CN101044405B (zh) 2015-06-10
EP1800136A2 (de) 2007-06-27

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