ATE554390T1 - Verfahren zur gewinnung von antikörpern - Google Patents

Verfahren zur gewinnung von antikörpern

Info

Publication number
ATE554390T1
ATE554390T1 AT04768084T AT04768084T ATE554390T1 AT E554390 T1 ATE554390 T1 AT E554390T1 AT 04768084 T AT04768084 T AT 04768084T AT 04768084 T AT04768084 T AT 04768084T AT E554390 T1 ATE554390 T1 AT E554390T1
Authority
AT
Austria
Prior art keywords
antigen
obtaining antibodies
cells
antibody
enriching
Prior art date
Application number
AT04768084T
Other languages
English (en)
Inventor
Alastair D G Lawson
Meryn Ruth Griffiths
Original Assignee
Ucb Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0319587A external-priority patent/GB0319587D0/en
Priority claimed from GB0402641A external-priority patent/GB0402641D0/en
Application filed by Ucb Pharma Sa filed Critical Ucb Pharma Sa
Application granted granted Critical
Publication of ATE554390T1 publication Critical patent/ATE554390T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT04768084T 2003-08-20 2004-08-12 Verfahren zur gewinnung von antikörpern ATE554390T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0319587A GB0319587D0 (en) 2003-08-20 2003-08-20 Biological products
GB0402641A GB0402641D0 (en) 2004-02-06 2004-02-06 Antibodies
PCT/GB2004/003523 WO2005019824A1 (en) 2003-08-20 2004-08-12 Methods for obtaining antibodies

Publications (1)

Publication Number Publication Date
ATE554390T1 true ATE554390T1 (de) 2012-05-15

Family

ID=34219619

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04768084T ATE554390T1 (de) 2003-08-20 2004-08-12 Verfahren zur gewinnung von antikörpern

Country Status (5)

Country Link
US (2) US20060263353A1 (de)
EP (1) EP1658500B1 (de)
AT (1) ATE554390T1 (de)
ES (1) ES2385829T3 (de)
WO (1) WO2005019824A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0605965D0 (en) 2006-03-24 2006-05-03 Univ East Anglia Fluorescence based detection of substances
EP2021463B1 (de) 2006-05-19 2016-11-23 Alder Biopharmaceuticals, Inc. Anbauverfahren zum erhalten einer klonpopulation von antigenspezifischen b-zellen
GB0619291D0 (en) 2006-09-29 2006-11-08 Ucb Sa Altered antibodies
US9512236B2 (en) 2006-12-19 2016-12-06 Ablynx N.V. Amino acid sequences directed against GPCRS and polypeptides comprising the same for the treatment of GPCR-related diseases and disorders
CA2673331A1 (en) 2006-12-19 2008-06-26 Ablynx N.V. Amino acid sequences directed against gpcrs and polypeptides comprising the same for the treatment of gpcr-related diseases and disorders
EP2102244A2 (de) 2006-12-19 2009-09-23 Ablynx N.V. Gegen metalloproteinase aus der adam-familie gerichtete aminosäuresequenzen und diese enthaltende polypeptide zur behandlung von mit adam in zusammenhang stehenden krankheiten und störungen
EP2650311A3 (de) 2007-11-27 2014-06-04 Ablynx N.V. Gegen heterodimere Cytokine und/oder deren Rezeptoren gerichtete Aminosäuresequenzen und Polypeptide damit
JP2011516520A (ja) 2008-04-07 2011-05-26 アブリンクス エン．ヴェー． Ｎｏｔｃｈ経路に指向性を有するアミノ酸配列及びその使用
EP2285833B1 (de) 2008-05-16 2014-12-17 Ablynx N.V. Gegen cxcr4 und andere gpcr gerichtete aminosäuresequenzen sowie verbindungen damit
LT2285408T (lt) 2008-06-05 2019-01-25 Ablynx N.V. Aminorūgščių sekos, nukreiptos prieš viruso apvalkalo baltymus, ir tokias sekas turintys polipeptidai, skirti virusinių ligų gydymui
CN102257003B (zh) 2008-12-19 2017-04-05 埃博灵克斯股份有限公司 用于产生针对细胞相关抗原如p2x7、cxcr7或cxcr4的免疫球蛋白的基因免疫
GB0903207D0 (en) 2009-02-25 2009-04-08 Ucb Pharma Sa Method for expressing multimeric proteins
ES2700442T3 (es) 2009-02-25 2019-02-15 Ucb Biopharma Sprl Método para producir anticuerpos
CA2781736A1 (en) * 2009-11-24 2011-06-03 Biassex Pty Ltd. Method for influencing sex selection in artificial insemination and apparatus for same
US20120321640A1 (en) 2009-12-01 2012-12-20 Ablynx N.V. Von willebrand factor specific binding agents and uses thereof
EP3309176B1 (de) 2009-12-14 2025-10-01 Ablynx N.V. Variable einzeldomänen-antikörper gegen ox40l, konstrukte und ihre therapeutische verwendung
US9120855B2 (en) 2010-02-10 2015-09-01 Novartis Ag Biologic compounds directed against death receptor 5
WO2011117423A1 (en) 2010-03-26 2011-09-29 Ablynx N.V. Immunoglobulin single variable domains directed against cxcr7
EP2571901B1 (de) 2010-05-20 2019-01-02 Ablynx N.V. Biologische stoffe im zusammenhang mit her3
AU2011328246B2 (en) 2010-11-08 2016-06-30 Ablynx N.V. CXCR2 binding polypeptides
CN103917560B (zh) 2011-03-28 2017-05-24 埃博灵克斯股份有限公司 双特异性抗‑cxcr7免疫球蛋白单可变结构域
UA117218C2 (uk) 2011-05-05 2018-07-10 Мерк Патент Гмбх Поліпептид, спрямований проти il-17a, il-17f та/або il17-a/f
US9328174B2 (en) 2012-05-09 2016-05-03 Novartis Ag Chemokine receptor binding polypeptides
WO2014093786A1 (en) * 2012-12-14 2014-06-19 Abbvie, Inc. Methods for increasing the efficiency of hybridoma generation
CA2862067A1 (en) * 2012-12-24 2014-07-03 Sorrento Therapeutics, Inc. Pharmaceutical composition of recombinant polyclonal immunoglobulins
US20160075766A1 (en) * 2013-05-21 2016-03-17 Roche Diagnostics Operations, Inc. Method for producing antibodies using ovine b-cells and uses thereof
EP3146040B1 (de) * 2014-05-19 2023-03-08 F. Hoffmann-La Roche AG Verfahren zur herstellung von schaf- b-zellen und deren verwendung
CN117321076A (zh) 2021-02-19 2023-12-29 美国卫生及公众服务部代表 中和SARS-CoV-2的单结构域抗体
EP4605077A1 (de) 2022-10-18 2025-08-27 Confo Therapeutics N.V. Gegen den melanocortin-4-rezeptor gerichtete aminosäuresequenzen und polypeptide damit zur behandlung von mc4r-bedingten erkrankungen und störungen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2090126C (en) 1990-08-02 2002-10-22 John W. Schrader Methods for the production of proteins with a desired function
US5256542A (en) * 1992-03-09 1993-10-26 Tanox Biosystems, Inc. Selecting low frequency antigen-specific single B lymphocytes with correction for background noise
US5213960A (en) * 1992-03-09 1993-05-25 Tanox Biosystems, Inc. Methods for selecting low frequency antigen-specific single B lymphocytes
JP3731891B2 (ja) * 1992-10-21 2006-01-05 ミルテンイ，ステファン 分泌生成物による細胞の直接選択
GB0118337D0 (en) * 2001-07-27 2001-09-19 Lonza Biologics Plc Method for selecting antibody expressing cells
ES2374068T3 (es) * 2002-12-03 2012-02-13 Ucb Pharma, S.A. Ensayo para identificar células productoras de anticuerpos.

Also Published As

Publication number Publication date
EP1658500A1 (de) 2006-05-24
ES2385829T3 (es) 2012-08-01
WO2005019824A1 (en) 2005-03-03
US20060263353A1 (en) 2006-11-23
EP1658500B1 (de) 2012-04-18
US8304200B2 (en) 2012-11-06
US20090275056A1 (en) 2009-11-05

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