ATE537271T1 - Toll-like-rezeptor-4-dysfunktion und biologische anwendungen davon - Google Patents

Toll-like-rezeptor-4-dysfunktion und biologische anwendungen davon

Info

Publication number
ATE537271T1
ATE537271T1 AT07819905T AT07819905T ATE537271T1 AT E537271 T1 ATE537271 T1 AT E537271T1 AT 07819905 T AT07819905 T AT 07819905T AT 07819905 T AT07819905 T AT 07819905T AT E537271 T1 ATE537271 T1 AT E537271T1
Authority
AT
Austria
Prior art keywords
tlr4
toll
receptor
subject
mutated
Prior art date
Application number
AT07819905T
Other languages
English (en)
Inventor
Lionel Apetoh
Guido Kroemer
Laurence Zitvogel
Original Assignee
Inst Gustave Roussy Igr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Gustave Roussy Igr filed Critical Inst Gustave Roussy Igr
Application granted granted Critical
Publication of ATE537271T1 publication Critical patent/ATE537271T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT07819905T 2006-07-18 2007-07-17 Toll-like-rezeptor-4-dysfunktion und biologische anwendungen davon ATE537271T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06291164A EP1881080A1 (de) 2006-07-18 2006-07-18 Funktionsstörung des Toll-ähnliches Rezeptors 4 und biologische Anwendungen davon
PCT/EP2007/057402 WO2008009693A1 (en) 2006-07-18 2007-07-17 Toll like receptor 4 dysfunction and the biological applications thereof

Publications (1)

Publication Number Publication Date
ATE537271T1 true ATE537271T1 (de) 2011-12-15

Family

ID=37402663

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07819905T ATE537271T1 (de) 2006-07-18 2007-07-17 Toll-like-rezeptor-4-dysfunktion und biologische anwendungen davon

Country Status (7)

Country Link
US (1) US8557517B2 (de)
EP (2) EP1881080A1 (de)
JP (1) JP2009543570A (de)
AT (1) ATE537271T1 (de)
DK (1) DK2038430T3 (de)
ES (1) ES2378847T3 (de)
WO (1) WO2008009693A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2209896B1 (de) 2007-10-26 2017-03-01 Dynavax Technologies Corporation Verfahren und zusammensetzungen zur hemmung von immunantworten und autoimmunität
EP2316032A1 (de) * 2008-08-20 2011-05-04 INSERM - Institut National de la Santé et de la Recherche Médicale Verfahren zur vorhersage des ansprechens auf eine antikrebsbehandlung mit einem agonisten von tlr7 oder einem agonisten von tlr8
EP2582398B1 (de) 2010-06-16 2016-04-13 Dynavax Technologies Corporation Verfahren zur behandlung unter verwendung von tlr7- und/oder tlr9-hemmern
EP2681314B1 (de) * 2011-03-03 2017-11-01 Quark Pharmaceuticals, Inc. Zusammensetzungen und verfahren zur behandlung von lungenerkrankungen und läsionen
WO2012135824A2 (en) * 2011-03-31 2012-10-04 H. Lee Moffitt Cancer Center And Research Institute, Inc. Method of screening for colon cancer using biomarkers
WO2012139945A1 (en) * 2011-04-14 2012-10-18 Universidad De Navarra Method for predicting survival in cancer patients
WO2013122545A1 (en) * 2012-02-14 2013-08-22 National University Of Singapore Synergistic combinations for use in treating cancer
JP2016535060A (ja) 2013-08-27 2016-11-10 ドイチェス クレブスフォルシュングスツェントルムＤｅｕｔｓｃｈｅｓ Ｋｒｅｂｓｆｏｒｓｃｈｕｎｇｓｚｅｎｔｒｕｍ 細胞傷害性ｔ細胞応答の修飾物質
WO2015179098A1 (en) 2014-05-21 2015-11-26 Integenx Inc. Fluidic cartridge with valve mechanism
CN107106983B (zh) 2014-10-22 2021-04-16 尹特根埃克斯有限公司 用于样品制备、处理和分析的系统和方法
EP3455630A4 (de) * 2016-05-13 2020-01-08 MBL International Corp. Peptidaustauschsystem und -verfahren

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0271521A4 (de) * 1986-05-09 1989-11-14 Sloan Kettering Inst Cancer Zubereitungen von lipopolysacchariden und natürlichem faktor zur antitumortherapie und verfahren zur behandlung.
US6982252B2 (en) * 2000-12-04 2006-01-03 Memorial Sloan-Kettering Cancer Center Inhibition of vacuolar proton ATPase activity and/or the modulation of acidic organelle function sensitizes cells to radiation, chemotherapy and biological agents
US20030165479A1 (en) * 2001-03-19 2003-09-04 Velleca Mark A. Methods for isolating proteins expressed by dendritic cells
US7195868B2 (en) * 2001-04-18 2007-03-27 Millennium Pharmaceuticals, Inc. Compositions and methods for the identification, assessment, prevention, and therapy of human cancers
GB0226251D0 (en) * 2002-11-11 2002-12-18 San Raffaele Centro Fond Acetylated protein
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
WO2005040208A2 (en) * 2003-10-21 2005-05-06 Androclus Therapeutics, Soa Peptides derived from heat shock proteins binding toll-like receptors 2 and 4 and their use
MX2007000770A (es) * 2004-07-20 2007-03-26 Schering Corp Induccion de apoptosis en celulas tumorales que expresan el receptor tipo toll.
CA2587676A1 (en) * 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna

Also Published As

Publication number Publication date
DK2038430T3 (da) 2012-01-30
JP2009543570A (ja) 2009-12-10
ES2378847T3 (es) 2012-04-18
US8557517B2 (en) 2013-10-15
US20100004161A1 (en) 2010-01-07
EP1881080A1 (de) 2008-01-23
EP2038430B1 (de) 2011-12-14
WO2008009693A1 (en) 2008-01-24
EP2038430A1 (de) 2009-03-25

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