ATE538122T1 - Acetamid- und carboxamid-derivate von azaadamantan sowie verfahren zu ihrer verwendung - Google Patents

Acetamid- und carboxamid-derivate von azaadamantan sowie verfahren zu ihrer verwendung

Info

Publication number: ATE538122T1
Authority: AT; Austria
Prior art keywords: acetamide; methods; azaadamantan; carboxamide derivatives; compounds
Prior art date: 2007-03-23

Application number

AT08732554T

Other languages

English (en)

Inventor

Marc J Scanio

Lei Shi

William BUNNELLE

Michael Schrimpf

Original Assignee

Abbott Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-03-23

Filing date

2008-03-20

Publication date

2012-01-15

2008-03-20 Application filed by Abbott Lab filed Critical Abbott Lab

2012-01-15 Application granted granted Critical

2012-01-15 Publication of ATE538122T1 publication Critical patent/ATE538122T1/de

Links

DLFVBJFMPXGRIB-UHFFFAOYSA-N Acetamide Chemical compound CC(N)=O DLFVBJFMPXGRIB-UHFFFAOYSA-N 0.000 title abstract 4
229940053202 antiepileptics carboxamide derivative Drugs 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 3
239000000203 mixture Substances 0.000 abstract 2
WENISBCJPGSITQ-UHFFFAOYSA-N 1-azatricyclo[3.3.1.13,7]decane Chemical class C1C(C2)CC3CC1CN2C3 WENISBCJPGSITQ-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Neurology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT08732554T 2007-03-23 2008-03-20 Acetamid- und carboxamid-derivate von azaadamantan sowie verfahren zu ihrer verwendung ATE538122T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US89674907P	2007-03-23	2007-03-23
PCT/US2008/057643 WO2008118743A1 (en)	2007-03-23	2008-03-20	Acetamide and carboxamide derivatives of azaadamantane and methods of use thereof

Publications (1)

Publication Number	Publication Date
ATE538122T1 true ATE538122T1 (de)	2012-01-15

Family

ID=39788935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT08732554T ATE538122T1 (de)	2007-03-23	2008-03-20	Acetamid- und carboxamid-derivate von azaadamantan sowie verfahren zu ihrer verwendung

Country Status (9)

Country	Link
US (2)	US8163914B2 (de)
EP (1)	EP2069346B1 (de)
JP (1)	JP5364878B2 (de)
CN (1)	CN101641356B (de)
AT (1)	ATE538122T1 (de)
CA (1)	CA2679874A1 (de)
ES (1)	ES2378116T3 (de)
MX (1)	MX2009010175A (de)
WO (1)	WO2008118743A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2010145208A1 (en) *	2009-06-19	2010-12-23	Abbott Laboratories	Diazahomoadamantane derivatives and methods of use thereof
CA2971413A1 (en)	2014-12-16	2016-06-23	Axovant Sciences Gmbh	Geminal substituted quinuclidine amide compounds as agonists of alpha-7 nicotinic acetylcholine receptors
CN107847494A (zh)	2015-06-10	2018-03-27	阿考温特科学股份有限公司	作为α7‑烟碱乙酰胆碱受体激动剂的氨基苯并异噁唑化合物
US10428062B2 (en)	2015-08-12	2019-10-01	Axovant Sciences Gmbh	Geminal substituted aminobenzisoxazole compounds as agonists of α7-nicotinic acetylcholine receptors

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8523211D0 (en)	1985-09-19	1985-10-23	Beecham Group Plc	Compounds
US5260303A (en)	1991-03-07	1993-11-09	G. D. Searle & Co.	Imidazopyridines as serotonergic 5-HT3 antagonists
US5280028A (en)	1992-06-24	1994-01-18	G. D. Searle & Co.	Benzimidazole compounds
US5521193A (en) *	1992-06-24	1996-05-28	G. D. Searle & Co.	Benzimidazole compounds
US5434151A (en)	1992-08-24	1995-07-18	Cytomed, Inc.	Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5840903A (en) *	1992-07-27	1998-11-24	G. D. Searle & Co.	4-aminomethyl-1-azaadamantane derived benzamides
US5399562A (en)	1994-02-04	1995-03-21	G. D. Searle & Co.	Indolones useful as serotonergic agents
BR9907172A (pt) *	1998-04-02	2000-10-10	Reynolds Tobacco Co R	Derivados de azatriciclo[3.3.1.1] decano e composições farmacêuticas contendo-os
US5986100A (en) *	1998-04-02	1999-11-16	Crooks; Peter Anthony	Pharmaceutical compositions and methods for use
KR20010072784A (ko) *	1998-08-18	2001-07-31	지. 카파트	무스카린성 작용제 및 길항제
CN1332726A (zh) *	1998-11-02	2002-01-23	卫福有限公司	吡咯烷化合物及其药物用途
US7897766B2 (en) *	2005-09-23	2011-03-01	Abbott Laboratories	Amino-aza-adamantane derivatives and methods of use

2008
- 2008-03-20 MX MX2009010175A patent/MX2009010175A/es active IP Right Grant
- 2008-03-20 ES ES08732554T patent/ES2378116T3/es active Active
- 2008-03-20 EP EP08732554A patent/EP2069346B1/de active Active
- 2008-03-20 AT AT08732554T patent/ATE538122T1/de active
- 2008-03-20 CN CN2008800095112A patent/CN101641356B/zh not_active Expired - Fee Related
- 2008-03-20 JP JP2009554737A patent/JP5364878B2/ja not_active Expired - Fee Related
- 2008-03-20 WO PCT/US2008/057643 patent/WO2008118743A1/en not_active Ceased
- 2008-03-20 US US12/052,050 patent/US8163914B2/en not_active Expired - Fee Related
- 2008-03-20 CA CA002679874A patent/CA2679874A1/en not_active Abandoned
2012
- 2012-03-23 US US13/428,040 patent/US20120190706A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP5364878B2 (ja)	2013-12-11
CA2679874A1 (en)	2008-10-02
CN101641356A (zh)	2010-02-03
EP2069346A4 (de)	2009-09-02
HK1131609A1 (en)	2010-01-29
US20120190706A1 (en)	2012-07-26
CN101641356B (zh)	2012-09-05
ES2378116T3 (es)	2012-04-09
JP2010522202A (ja)	2010-07-01
EP2069346A1 (de)	2009-06-17
MX2009010175A (es)	2009-10-12
EP2069346B1 (de)	2011-12-21
US20080255179A1 (en)	2008-10-16
WO2008118743A1 (en)	2008-10-02
US8163914B2 (en)	2012-04-24

Publication	Publication Date	Title
CY1112653T1 (el)	2016-02-10	Κρυσταλλικες τροποποιησεις της πυρακλοστροβινης
EA201000777A1 (ru)	2010-12-30	Ингибиторы репликации вируса иммунодефицита человека
BRPI1015043A2 (pt)	2019-07-09	derivados de diazahomoadamantano e métodos de uso dos mesmos
CY1115919T1 (el)	2017-01-25	Ενωσεις ενεργοποιησης τελομερασης και μεθοδοι χρησης αυτων
WO2007125103A3 (en)	2008-04-10	Benzamide glucokinase activators
DK2137537T3 (da)	2013-07-29	Sammensætninger og anvendelser til behandling af multipel sklerose
EA201170227A1 (ru)	2011-06-30	Имидазолкарбоксамиды
EA201490922A1 (ru)	2015-03-31	ПРОИЗВОДНЫЕ ГИДАНТОИНА, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ Kv3-КАНАЛОВ
DK1836169T5 (da)	2023-10-09	Sammensætninger og fremgangsmåder til behandling af celleproliferationslidelser
EA201070238A1 (ru)	2010-08-30	Соединения пиримидина
PA8713501A1 (es)	2009-09-17	INHIBIDORES DE 11-BETA HIDROXIESTEROIDE DEHIDROGENASA - 11ßHSD1
UA99936C2 (en)	2012-10-25	Biaryl substituted azabicyclic alkane derivatives
TW201713640A (en)	2017-04-16	Bruton's tyrosine kinase inhibitors
DE602007012072D1 (de)	2011-03-03	Orantagonisten
ATE509931T1 (de)	2011-06-15	Azaadamantanester- und carbamatderivate sowie anwendungsverfahren dafür
ATE489371T1 (de)	2010-12-15	Benzamidglucokinaseaktivatoren
MA32544B1 (fr)	2011-08-01	Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
WO2010030983A3 (en)	2010-07-01	Pyrazole carboxamide inhibitors of factor xa
WO2010053573A3 (en)	2010-07-29	Screen for inhibitors of filovirus and uses therefor
WO2009002440A3 (en)	2009-02-26	Compositions comprising human egfr-sirna and methods of use
UA96994C2 (ru)	2011-12-26	Производные 7-алкинил-1,8-нафтиридонов, способ их получения и их применения в терапии
EA201001481A1 (ru)	2011-06-30	Производные третичного амина в качестве ингибиторов фосфодиэстеразы-4
WO2009086163A3 (en)	2009-09-03	Thiazolylidine urea and amide derivatives and methods of use thereof
MX2009010176A (es)	2009-10-12	Derivados de aza-adamantano 4-substituidos y metodos de uso de los mismos.
ATE448234T1 (de)	2009-11-15	Olanzapin-analoga und verfahren zu ihrer verwendung