ATE538790T1 - Scopolamin für die behandlung von depression und ängstlichkeit - Google Patents
Scopolamin für die behandlung von depression und ängstlichkeitInfo
- Publication number
- ATE538790T1 ATE538790T1 AT06760136T AT06760136T ATE538790T1 AT E538790 T1 ATE538790 T1 AT E538790T1 AT 06760136 T AT06760136 T AT 06760136T AT 06760136 T AT06760136 T AT 06760136T AT E538790 T1 ATE538790 T1 AT E538790T1
- Authority
- AT
- Austria
- Prior art keywords
- scopolamine
- anxiety
- depression
- treatment
- analog
- Prior art date
Links
- 229930000680 A04AD01 - Scopolamine Natural products 0.000 title abstract 3
- STECJAGHUSJQJN-GAUPFVANSA-N Hyoscine Natural products C1([C@H](CO)C(=O)OC2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-GAUPFVANSA-N 0.000 title abstract 3
- STECJAGHUSJQJN-UHFFFAOYSA-N N-Methyl-scopolamin Natural products C1C(C2C3O2)N(C)C3CC1OC(=O)C(CO)C1=CC=CC=C1 STECJAGHUSJQJN-UHFFFAOYSA-N 0.000 title abstract 3
- 229960002646 scopolamine Drugs 0.000 title abstract 3
- 208000019901 Anxiety disease Diseases 0.000 title abstract 2
- 208000020401 Depressive disease Diseases 0.000 title abstract 2
- 230000036506 anxiety Effects 0.000 title abstract 2
- STECJAGHUSJQJN-VJQRDGCPSA-N chembl3084722 Chemical compound C1([C@@H](CO)C(=O)O[C@@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-VJQRDGCPSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- STECJAGHUSJQJN-FWXGHANASA-N scopolamine Chemical compound C1([C@@H](CO)C(=O)O[C@H]2C[C@@H]3N([C@H](C2)[C@@H]2[C@H]3O2)C)=CC=CC=C1 STECJAGHUSJQJN-FWXGHANASA-N 0.000 abstract 2
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229940001470 psychoactive drug Drugs 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/137,114 US8859585B2 (en) | 2005-05-25 | 2005-05-25 | Scopolamine for the treatment of depression and anxiety |
| PCT/US2006/019335 WO2006127418A1 (en) | 2005-05-25 | 2006-05-18 | Scopolamine for the treatment of depression and anxiety |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE538790T1 true ATE538790T1 (de) | 2012-01-15 |
Family
ID=36942428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06760136T ATE538790T1 (de) | 2005-05-25 | 2006-05-18 | Scopolamin für die behandlung von depression und ängstlichkeit |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8859585B2 (de) |
| EP (1) | EP1896025B1 (de) |
| AT (1) | ATE538790T1 (de) |
| AU (1) | AU2006251893A1 (de) |
| CA (1) | CA2610025C (de) |
| WO (1) | WO2006127418A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8859585B2 (en) | 2005-05-25 | 2014-10-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Scopolamine for the treatment of depression and anxiety |
| US20070010550A1 (en) * | 2005-07-08 | 2007-01-11 | The Board Of Regents Of The University Of Texas | Scopolamine to Reduce or Eliminate Hot Flashes, Night Sweats, and Insomnia |
| US8653145B2 (en) * | 2005-09-22 | 2014-02-18 | Eaton Scientific Systems, Ltd. | Method for alleviating climacteric symptoms |
| US7893053B2 (en) | 2006-06-16 | 2011-02-22 | Theracos, Inc. | Treating psychological conditions using muscarinic receptor M1 antagonists |
| US8748419B2 (en) | 2006-06-16 | 2014-06-10 | Theracos, Inc. | Treating obesity with muscarinic receptor M1 antagonists |
| US20100266682A1 (en) * | 2008-12-10 | 2010-10-21 | Nipun Davar | Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same |
| US20100143486A1 (en) * | 2008-12-10 | 2010-06-10 | Nipun Davar | Polyethylene glycol-coated sodium carbonate as a pharmaceutical excipient and compositions produced from the same |
| WO2011163231A2 (en) | 2010-06-21 | 2011-12-29 | Theracos, Inc. | Combination therapy for the treatment of diabetes |
| EP2830604A4 (de) * | 2012-03-30 | 2015-08-19 | Gen Hospital Corp | Zusammensetzungen mit scopolamin und ketamin zur behandlung von depressionen |
| CN102813649A (zh) * | 2012-08-01 | 2012-12-12 | 新乡医学院 | 氢溴酸樟柳碱在制备治疗抑郁症药物中的应用 |
| CN106714790A (zh) | 2014-07-22 | 2017-05-24 | 托马斯·P·杜利 | 使用β肾上腺素能受体拮抗剂和毒蕈碱受体拮抗剂组合的治疗惊恐和焦虑症状的药物组合物和方法 |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| US20220000881A1 (en) * | 2018-10-31 | 2022-01-06 | Repurposed Therapeutics, Inc. Dba Defender | Treatment of exposure to chlorine gas with scopolamine |
| US12396988B2 (en) * | 2019-04-04 | 2025-08-26 | Board Of Regents, The University Of Texas System | Methods of using muscarinic antagonists in the treatment of depression |
| KR20220009954A (ko) | 2019-04-17 | 2022-01-25 | 컴퍼스 패쓰파인더 리미티드 | 신경인지 장애, 만성 통증을 치료하고 염증을 감소시키는 방법 |
| US20230256004A1 (en) * | 2020-07-09 | 2023-08-17 | Light Aqua Llc | Compositions and methods for treating mood disorders and circadian rhythm sleep disorders |
| US20240050502A1 (en) * | 2020-12-16 | 2024-02-15 | Caamtech, Inc. | Amanita muscaria compounds |
| CN114848613A (zh) * | 2022-05-09 | 2022-08-05 | 山东中医药大学 | 一种东莨菪碱可溶性微针贴片及其制备方法和应用 |
| CN116731007B (zh) * | 2023-08-16 | 2023-10-24 | 成都第一制药有限公司 | 一种氢溴酸东莨菪碱的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1601438A (de) * | 1968-10-17 | 1970-08-24 | ||
| CA1022930A (en) | 1974-12-24 | 1977-12-20 | Rudolf Bauer | Anti-bronchial disease compounds |
| DE3926751A1 (de) | 1989-08-12 | 1991-02-14 | Lettko Herbert Aerochem | Lagerfaehige, alkoholische alkaloid-loesung, sowie verfahren zu deren stabilisierung und verfahren zur ausbringung einer exakten menge von 1,65 mg atropin-base pro einzelanwendung |
| DE69732306T2 (de) | 1997-01-16 | 2006-01-12 | Massachusetts Institute Of Technology, Cambridge | Zubereitung von partikelhaltigen arzneimitteln zur inhalation |
| US20040087576A1 (en) * | 2002-11-05 | 2004-05-06 | Haracz John L. | Antimnemonic therapy for hypermemory syndromes |
| AU2005232748A1 (en) * | 2004-04-13 | 2005-10-27 | The Mclean Hospital Corporation | R(-)-11-hydroxyaporphine derivatives and uses thereof |
| US8859585B2 (en) | 2005-05-25 | 2014-10-14 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Scopolamine for the treatment of depression and anxiety |
-
2005
- 2005-05-25 US US11/137,114 patent/US8859585B2/en active Active
-
2006
- 2006-05-18 AT AT06760136T patent/ATE538790T1/de active
- 2006-05-18 WO PCT/US2006/019335 patent/WO2006127418A1/en not_active Ceased
- 2006-05-18 EP EP06760136A patent/EP1896025B1/de active Active
- 2006-05-18 CA CA2610025A patent/CA2610025C/en active Active
- 2006-05-18 AU AU2006251893A patent/AU2006251893A1/en not_active Abandoned
-
2014
- 2014-09-05 US US14/478,442 patent/US9707220B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20060270698A1 (en) | 2006-11-30 |
| US9707220B2 (en) | 2017-07-18 |
| EP1896025B1 (de) | 2011-12-28 |
| WO2006127418A1 (en) | 2006-11-30 |
| US20140378501A1 (en) | 2014-12-25 |
| US8859585B2 (en) | 2014-10-14 |
| CA2610025A1 (en) | 2006-11-30 |
| CA2610025C (en) | 2014-07-22 |
| AU2006251893A1 (en) | 2006-11-30 |
| EP1896025A1 (de) | 2008-03-12 |
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