ATE539687T1 - Selbstbetätigter applikator für eine mikroprojektionsanordnung - Google Patents

Selbstbetätigter applikator für eine mikroprojektionsanordnung

Info

Publication number
ATE539687T1
ATE539687T1 AT04796104T AT04796104T ATE539687T1 AT E539687 T1 ATE539687 T1 AT E539687T1 AT 04796104 T AT04796104 T AT 04796104T AT 04796104 T AT04796104 T AT 04796104T AT E539687 T1 ATE539687 T1 AT E539687T1
Authority
AT
Austria
Prior art keywords
self
microprojection arrangement
actuated applicator
applicator
actuated
Prior art date
Application number
AT04796104T
Other languages
English (en)
Inventor
Joseph Trautman
Lorin Olson
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE539687T1 publication Critical patent/ATE539687T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/92Impactors or extractors, e.g. for removing intramedullary devices
    • A61B2017/922Devices for impaction, impact element
    • A61B2017/924Impact element driving means
    • A61B2017/925Impact element driving means a spring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT04796104T 2003-10-31 2004-10-21 Selbstbetätigter applikator für eine mikroprojektionsanordnung ATE539687T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51618203P 2003-10-31 2003-10-31
PCT/US2004/035052 WO2005044333A2 (en) 2003-10-31 2004-10-21 Self-actuating applicator for microprojection array

Publications (1)

Publication Number Publication Date
ATE539687T1 true ATE539687T1 (de) 2012-01-15

Family

ID=34572872

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04796104T ATE539687T1 (de) 2003-10-31 2004-10-21 Selbstbetätigter applikator für eine mikroprojektionsanordnung

Country Status (13)

Country Link
US (2) US7097631B2 (de)
EP (1) EP1680154B1 (de)
JP (1) JP4682144B2 (de)
KR (1) KR20060099523A (de)
CN (1) CN100571643C (de)
AR (1) AR046696A1 (de)
AT (1) ATE539687T1 (de)
AU (1) AU2004287414B2 (de)
BR (1) BRPI0415629A (de)
CA (1) CA2543641A1 (de)
ES (1) ES2377647T3 (de)
TW (1) TW200633675A (de)
WO (1) WO2005044333A2 (de)

Families Citing this family (291)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2253549C (en) * 1996-06-18 2005-10-25 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
DE60138411D1 (de) * 2000-10-13 2009-05-28 Alza Corp Vorrichtung und verfahren zum durchstechen der haut mit micronadeln
ATE416692T1 (de) * 2000-10-13 2008-12-15 Alza Corp Mikronadelelementhalter für schlagapplikator
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
NZ525551A (en) * 2000-10-26 2005-09-30 Alza Corp Transdermal drug delivery devices having coated microprotrusions
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DE10057832C1 (de) 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
WO2002074173A1 (en) * 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
AU2002348683A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Method and apparatus for lancet launching device integrated onto a blood-sampling cartridge
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
ATE497731T1 (de) 2001-06-12 2011-02-15 Pelikan Technologies Inc Gerät zur erhöhung der erfolgsrate im hinblick auf die durch einen fingerstich erhaltene blutausbeute
CA2448681C (en) 2001-06-12 2014-09-09 Pelikan Technologies, Inc. Integrated blood sampling analysis system with multi-use sampling module
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
AU2002312521A1 (en) 2001-06-12 2002-12-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
ATE485766T1 (de) 2001-06-12 2010-11-15 Pelikan Technologies Inc Elektrisches betätigungselement für eine lanzette
ES2336081T3 (es) 2001-06-12 2010-04-08 Pelikan Technologies Inc. Dispositivo de puncion de auto-optimizacion con medios de adaptacion a variaciones temporales en las propiedades cutaneas.
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7481776B2 (en) 2002-04-19 2009-01-27 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
WO2004098684A2 (en) * 2003-05-08 2004-11-18 Novo Nordisk A/S Skin mountable injection device with a detachable needle insertion actuation
EP1475113A1 (de) * 2003-05-08 2004-11-10 Novo Nordisk A/S Externer Nadeleinsetzer
WO2004098683A1 (en) 2003-05-08 2004-11-18 Novo Nordisk A/S Internal needle inserter
EP1628567B1 (de) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Verfahren und vorrichtung zur injektion von flüssigkeit
EP1633235B1 (de) 2003-06-06 2014-05-21 Sanofi-Aventis Deutschland GmbH Gerät für die entnahme von körperflüssigkeiten und analyten-nachweis
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7604592B2 (en) 2003-06-13 2009-10-20 Pelikan Technologies, Inc. Method and apparatus for a point of care device
KR20060038407A (ko) * 2003-06-30 2006-05-03 알자 코포레이션 비휘발성 반대이온을 포함하는 코팅된 미세돌출부용 제제
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
EP1502613A1 (de) 2003-08-01 2005-02-02 Novo Nordisk A/S Gerät mit Rückziehvorrichting für eine Nadel
EP1671096A4 (de) 2003-09-29 2009-09-16 Pelikan Technologies Inc Verfahren und apparatur für eine verbesserte probeneinfangvorrichtung
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
BRPI0415466A (pt) * 2003-10-24 2006-12-19 Alza Corp método e sistema de pré-tratamento para intensificar a distribuição transdérmica de fármacos
AU2004287412A1 (en) * 2003-10-28 2005-05-19 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
ES2377647T3 (es) 2003-10-31 2012-03-29 Alza Corporation Aplicador auto-actuado para ordenamiento de microproyecciones
EP1706171A1 (de) * 2003-12-29 2006-10-04 3M Innovative Properties Company Medizinprodukte und diese enthaltende sets
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (de) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Verfahren und vorrichtung zur verbesserung der fluidströmung und der probennahme
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
WO2005094526A2 (en) * 2004-03-24 2005-10-13 Corium International, Inc. Transdermal delivery device
ATE424228T1 (de) 2004-03-26 2009-03-15 Unomedical As Infusionsset
WO2005094920A1 (en) 2004-03-30 2005-10-13 Novo Nordisk A/S Actuator system comprising lever mechanism
CN101120101A (zh) * 2004-04-13 2008-02-06 阿尔扎公司 多联疫苗透皮释放的装置和方法
US7556821B2 (en) 2004-05-13 2009-07-07 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US7591806B2 (en) * 2004-05-18 2009-09-22 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
WO2006011062A2 (en) 2004-05-20 2006-02-02 Albatros Technologies Gmbh & Co. Kg Printable hydrogel for biosensors
WO2005120365A1 (en) 2004-06-03 2005-12-22 Pelikan Technologies, Inc. Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1773444B1 (de) * 2004-06-10 2017-09-20 3M Innovative Properties Company Vorrichtung und kit zur pflasterapplikation
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
WO2006020841A2 (en) * 2004-08-11 2006-02-23 Alza Corporation Apparatus and method for transdermal delivery of natriuretic peptides
CA2579509A1 (en) * 2004-09-08 2006-03-16 Alza Corporation Microprojection array with improved skin adhesion and compliance
JP4927752B2 (ja) 2004-11-18 2012-05-09 スリーエム イノベイティブ プロパティズ カンパニー マイクロニードルアレイアプリケーターおよび保持装置
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
WO2006072004A2 (en) * 2004-12-30 2006-07-06 Pelikan Technologies, Inc. Method and apparatus for analyte measurement test time
JP2008528086A (ja) 2005-01-24 2008-07-31 ノボ・ノルデイスク・エー/エス 保護された穿刺装置を有する医療用装置
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
US10035008B2 (en) 2005-04-07 2018-07-31 3M Innovative Properties Company System and method for tool feedback sensing
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
EP1904158B1 (de) 2005-06-24 2013-07-24 3M Innovative Properties Company Faltbares Pflaster mit Mikronadelnanordnung
EP2474338B1 (de) * 2005-06-27 2013-07-24 3M Innovative Properties Company Vorrichtung zum Aufbringen einer Mikronadelanordnung
AU2006291157A1 (en) * 2005-09-12 2007-03-22 Alza Corporation Coatable transdermal delivery microprojection assembly
ATE480278T1 (de) * 2005-09-12 2010-09-15 Unomedical As Einfürungssystem für ein infusionsset mit einem ersten und zweiten federeinheit
DE602006006477D1 (de) 2005-12-23 2009-06-04 Unomedical As Verabreichungsgerät
AU2007219546B8 (en) 2006-02-28 2012-07-05 Unomedical A/S Inserter for infusion part and infusion part provided with needle protector
EP1997234A1 (de) * 2006-03-13 2008-12-03 Novo Nordisk A/S Medizinisches system mit zweifach verwendbaren kommunikationsmitteln
WO2007104755A1 (en) * 2006-03-13 2007-09-20 Novo Nordisk A/S Secure pairing of electronic devices using dual means of communication
AU2007225056A1 (en) * 2006-03-15 2007-09-20 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
US20070299388A1 (en) * 2006-04-25 2007-12-27 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
WO2007141210A1 (en) 2006-06-06 2007-12-13 Novo Nordisk A/S Assembly comprising skin-mountable device and packaging therefore
WO2007140783A2 (en) 2006-06-07 2007-12-13 Unomedical A/S Inserter for transcutaneous sensor
KR20090028701A (ko) 2006-06-09 2009-03-19 우노메디컬 에이/에스 장착 패드
RU2443436C2 (ru) * 2006-08-02 2012-02-27 Уномедикал А/С Канюльное и доставочное устройство
CA2659077A1 (en) * 2006-08-02 2008-02-07 Unomedical A/S Insertion device
EP1917990A1 (de) 2006-10-31 2008-05-07 Unomedical A/S Infusionsset
WO2008053481A1 (en) * 2006-11-01 2008-05-08 Svip 6 Llc Microneedle arrays
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US8821446B2 (en) * 2007-01-22 2014-09-02 Corium International, Inc. Applicators for microneedles
KR20090117749A (ko) * 2007-02-02 2009-11-12 우노메디컬 에이/에스 약물 공급장치
CA2676811A1 (en) * 2007-02-02 2008-08-07 Unomedical A/S Injection site for injecting medication
ES2817249T3 (es) 2007-04-16 2021-04-06 Corium Inc Matrices de microagujas obtenidas mediante disolución y colada que contienen un principio activo
EP2155311B1 (de) 2007-06-20 2013-01-02 Unomedical A/S Verfahren und gerät zur herstellung dieses katheters
EP2185224A1 (de) 2007-07-03 2010-05-19 Unomedical A/S Einführungsinstrument mit bistabilen gleichgewichtszuständen
RU2010104457A (ru) 2007-07-10 2011-08-20 Уномедикал А/С (Dk) Устройство ввода с двумя пружинами
NZ582226A (en) 2007-07-18 2011-12-22 Unomedical As Insertion device with a pivoting action from a first to a second position and longitudinal action to a third position in the direction of insertion.
AU2008283929B2 (en) 2007-08-06 2013-10-10 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
EP2200677A1 (de) * 2007-09-17 2010-06-30 ICU Medical, Inc. Einführungsinstrumente für infusionsvorrichtungen
GB0719577D0 (en) * 2007-10-08 2007-11-14 Kirby Andrew J Microimplant devices and methods of making and use thereof
WO2009048607A1 (en) 2007-10-10 2009-04-16 Corium International, Inc. Vaccine delivery via microneedle arrays
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
CA2701772A1 (en) 2007-10-31 2009-05-07 Novo Nordisk A/S Non-porous material as sterilization barrier
CA2745339C (en) 2007-12-24 2016-06-28 The University Of Queensland Coating method
AU2009212106B9 (en) 2008-02-07 2014-05-22 Vaxxas Pty Limited Patch production
RU2010137844A (ru) 2008-02-13 2012-03-20 Уномедикал А/С (Dk) Уплотнение между канюльной частью и путем прохождения текучей среды
CA2715667A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
PL2712622T3 (pl) * 2008-05-21 2017-01-31 Ferring B.V. Ulegająca rozpadowi w ustach desmopresyna do zwiększania początkowego okresu snu niezakłócanego przez nokturię
WO2009140735A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection by microneedle patch with analyte selective reagents.
US20110223204A1 (en) * 2008-06-04 2011-09-15 Bradford J Duft Treatment of pain with gap junction modulation compounds
JP2011522616A (ja) * 2008-06-04 2011-08-04 セブンス センス バイオシステムズ,インコーポレーテッド シングルステップ診断のための組成物および方法
EP3187219B2 (de) 2008-12-02 2026-03-04 Allergan, Inc. Injektionsvorrichtung
CN102256657A (zh) 2008-12-22 2011-11-23 犹诺医药有限公司 包括粘合垫的医疗器械
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
US9295417B2 (en) 2011-04-29 2016-03-29 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
WO2010101626A1 (en) 2009-03-02 2010-09-10 Seventh Sense Biosystems, Inc. Techniques and devices associated with blood sampling
US9041541B2 (en) 2010-01-28 2015-05-26 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
KR101030752B1 (ko) * 2009-04-09 2011-04-26 한국생명공학연구원 유체전달을 조절할 수 있는 마이크로 니들 유닛
US20120089117A1 (en) * 2009-04-23 2012-04-12 National University Of Singapore Apparatus that includes nano-sized projections and a method for manufacture thereof
EP2429627B1 (de) * 2009-04-24 2017-06-14 Corium International, Inc. Verfahren zur herstellung von mikroprojektionsarrays
US8690838B2 (en) 2009-05-01 2014-04-08 Nanbu Plastics Co., Ltd. Transdermal administration device
WO2011005971A1 (en) * 2009-07-09 2011-01-13 Cook Incorporated Spring action medical device
JP2013500099A (ja) 2009-07-30 2013-01-07 ウノメディカル・アー/エス 水平方向の可動部材を備えた挿入デバイス
JP5702384B2 (ja) 2009-07-31 2015-04-15 スリーエム イノベイティブ プロパティズ カンパニー 中空マイクロニードルアレイ
CN102548598B (zh) 2009-08-07 2014-09-17 犹诺医药有限公司 具有传感器和一个或多个插管的传送装置
WO2011053787A2 (en) * 2009-10-30 2011-05-05 Seventh Sense Biosystems, Inc. Systems and methods for application to skin and control of actuation, delivery and/or perception thereof
CN102695501A (zh) 2009-11-09 2012-09-26 聚光灯技术合伙有限责任公司 碎裂水凝胶
CN106913902A (zh) 2009-11-09 2017-07-04 聚光灯技术合伙有限责任公司 多糖基水凝胶
WO2011065972A2 (en) * 2009-11-24 2011-06-03 Seventh Sense Biosystems, Inc. Patient-enacted sampling technique
USD638534S1 (en) 2010-01-08 2011-05-24 Ratio, Inc. Drug delivery device
USD619245S1 (en) 2010-01-08 2010-07-06 Ratio, Inc. Drug delivery device
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
CN102791197B (zh) * 2010-01-13 2016-03-23 第七感生物系统有限公司 取样装置接口
CN102811754B (zh) * 2010-01-13 2017-05-17 第七感生物系统有限公司 流体的快速输送和/或抽出
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
CA2792138A1 (en) 2010-03-30 2011-10-06 Unomedical A/S Medical device
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
EP2566501B1 (de) 2010-05-04 2019-03-13 Corium International, Inc. Verfahren und vorrichtung zur transdermalen verabreichung von parathormon mithilfe eines mikroprojektions-arrays
BR112012028263B1 (pt) 2010-05-04 2020-06-02 Corium, Inc. Aplicador e dispositivo para matriz de microprojeção
HUE030072T2 (en) 2010-05-12 2017-04-28 Radius Health Inc Therapeutic prescriptions
WO2012006677A1 (en) 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
US20120016308A1 (en) 2010-07-16 2012-01-19 Seventh Sense Biosystems, Inc. Low-pressure packaging for fluid devices
US20130158482A1 (en) 2010-07-26 2013-06-20 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
US20120039809A1 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
EP2433663A1 (de) 2010-09-27 2012-03-28 Unomedical A/S Einführsystem
US9133182B2 (en) 2010-09-28 2015-09-15 Radius Health, Inc. Selective androgen receptor modulators
EP2436412A1 (de) 2010-10-04 2012-04-04 Unomedical A/S Sprinklerkanüle
WO2012046816A1 (ja) 2010-10-07 2012-04-12 久光製薬株式会社 アプリケータ
US9017289B2 (en) * 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
US8668675B2 (en) 2010-11-03 2014-03-11 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
JP2012100783A (ja) * 2010-11-08 2012-05-31 Nanbu Plastics Co Ltd 薬液供給装置
WO2012064802A1 (en) 2010-11-09 2012-05-18 Seventh Sense Biosystems, Inc. Systems and interfaces for blood sampling
WO2012071559A2 (en) * 2010-11-23 2012-05-31 Presage Biosciences, Inc. Therapeutic methods and compositions for solid delivery
US8814831B2 (en) * 2010-11-30 2014-08-26 Becton, Dickinson And Company Ballistic microneedle infusion device
EP2460553A1 (de) * 2010-12-02 2012-06-06 Debiotech S.A. Vorrichtung für das Einsetzen von Nadeln
AU2011349277A1 (en) 2010-12-22 2013-06-27 Valeritas, Inc. Microneedle patch applicator
EP2699252B1 (de) * 2011-04-22 2017-10-25 Radius Health, Inc. Verfahren zur arzneimittelverabreichung für pth, pthrp und ähnliche peptide
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
EP3236259A1 (de) 2011-04-29 2017-10-25 Seventh Sense Biosystems, Inc. Plasma- oder serumherstellung und entfernung von flüssigkeiten bei reduziertem druck
JP6121400B2 (ja) 2011-04-29 2017-04-26 セブンス センス バイオシステムズ,インコーポレーテッド 流体の送達および/または受け取り
US20140207101A1 (en) * 2011-06-09 2014-07-24 3M Innovative Properties Company Microstructure device with removable microstructure patch
KR101973824B1 (ko) 2011-07-27 2019-04-29 히사미쓰 세이야꾸 가부시키가이샤 어플리케이터
WO2013036602A1 (en) 2011-09-07 2013-03-14 3M Innovative Properties Company Delivery system for hollow microneedle arrays
NL2007461C2 (en) * 2011-09-23 2013-03-26 Ambro B V System for transporting fluid across or into a biological barrier, device and capsule as part of the system.
EP2572741A1 (de) * 2011-09-23 2013-03-27 Sanofi-Aventis Deutschland GmbH Medikamentenabgabevorrichtung und Auslösemechanismus für eine Medikamentenabgabevorrichtung
EP2763723B1 (de) 2011-10-05 2016-04-13 Unomedical A/S Inserter zum gleichzeitigen einsetzen mehrerer transkutaner teile
WO2013051568A1 (ja) 2011-10-06 2013-04-11 久光製薬株式会社 アプリケータ
US20140236090A1 (en) * 2011-10-12 2014-08-21 3M Innovative Properties Company Integrated microneedle array delivery system
CN103874518A (zh) * 2011-10-12 2014-06-18 3M创新有限公司 一体化微针阵列递送系统
AU2012323782B2 (en) 2011-10-12 2017-04-06 Vaxxas Pty Limited Delivery device
EP2583715A1 (de) 2011-10-19 2013-04-24 Unomedical A/S Infusionsschlauchsystem und Herstellungsverfahren
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
EP2771043A4 (de) 2011-10-28 2015-04-29 Presage Biosciences Inc Wirkstofffreisetzungsverfahren
DE102011119055B4 (de) * 2011-11-16 2013-08-14 Lts Lohmann Therapie-Systeme Ag Zylinder-Kolben-Einheit mit Klebescheibe II
EP2835147B1 (de) * 2012-04-05 2019-11-13 Hisamitsu Pharmaceutical Co., Inc. Punktionsvorrichtung
DE202012006290U1 (de) * 2012-06-29 2013-09-30 Lukas Pregenzer Inkontinenzimplantat
JP6091818B2 (ja) * 2012-08-28 2017-03-08 コスメディ製薬株式会社 マイクロニードルパッチ投与装置
WO2014058746A1 (en) * 2012-10-10 2014-04-17 3M Innovative Properties Company Force-controlled applicator for applying a microneedle device to skin
EP2934660B1 (de) 2012-12-21 2019-07-17 Corium, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe und verfahren zur herstellung davon
WO2014110016A1 (en) 2013-01-08 2014-07-17 3M Innovative Properties Company Applicator for applying a microneedle device to skin
EP4094799A1 (de) 2013-03-12 2022-11-30 Corium, Inc. Mikroprojektionsapplikatoren
WO2014150285A2 (en) 2013-03-15 2014-09-25 Corium International, Inc. Multiple impact microprojection applicators and methods of use
US10384046B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray for delivery of therapeutic agent and methods of use
EP2968119B1 (de) 2013-03-15 2019-09-18 Corium International, Inc. Mikroarray zur freisetzung therapeutischer wirkstoffe, verfahren zur verwendung und verfahren zur herstellung
US9319916B2 (en) 2013-03-15 2016-04-19 Isco International, Llc Method and appartus for signal interference processing
US10384045B2 (en) 2013-03-15 2019-08-20 Corium, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US9895520B2 (en) * 2013-05-31 2018-02-20 3M Innovative Properties Company Microneedle injection apparatus comprising a dual cover
SG11201509546PA (en) 2013-05-31 2015-12-30 3M Innovative Properties Co Microneedle injection apparatus comprising an inverted actuator
KR102274902B1 (ko) 2013-05-31 2021-07-07 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 주사 및 주입 장치 및 그의 사용 방법
EP3027263A1 (de) 2013-07-30 2016-06-08 ZP Opco, Inc. Flacher mikronadelfeldapplikator
CN105555353B (zh) 2013-09-18 2019-01-01 考司美德制药株式会社 一种微针贴应用装置以及一种贴支架
DE102013021058B4 (de) * 2013-12-18 2017-10-12 Gerresheimer Regensburg Gmbh Vorrichtung zur Applizierung eines Nadelarrays auf biologischem Gewebe
GB201401133D0 (en) 2014-01-23 2014-03-12 Renephra Ltd Fluid extraction device, applicator device and associated methods
CN106061546A (zh) * 2014-02-10 2016-10-26 Lts勒曼治疗系统股份公司 微针系统及其制造方法
ES3055185T3 (en) 2014-03-28 2026-02-10 Univ Duke Treatment of an estrogen receptor positive breast cancer using a selective estrogen receptor modulator
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
US20160038434A1 (en) * 2014-08-01 2016-02-11 Innovative Drive Corporation Device and method for application of a transdermal membrane
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
WO2016123665A1 (en) 2015-02-02 2016-08-11 Vaxxas Pty Limited Microprojection array applicator and method
BR112017019272A2 (pt) 2015-03-10 2018-05-02 Allergan Pharmaceuticals Holdings Ireland Unlimited Company injetor de múltiplas agulhas
KR20250152679A (ko) 2015-04-29 2025-10-23 래디어스 파마슈티컬스, 인코포레이티드 암을 치료하는 방법
US10857093B2 (en) 2015-06-29 2020-12-08 Corium, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2017023404A (ja) 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
WO2017045031A1 (en) 2015-09-18 2017-03-23 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
CA2999538A1 (en) 2015-09-28 2017-04-06 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
CN112089961B (zh) * 2015-12-21 2022-08-09 美德阿利克斯株式会社 微针贴片施用器及其壳体
WO2017143345A1 (en) 2016-02-19 2017-08-24 Zp Opco, Inc. Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
WO2017159779A1 (ja) 2016-03-16 2017-09-21 コスメディ製薬株式会社 マイクロニードルパッチケース
US10596321B2 (en) 2016-04-08 2020-03-24 Allergan, Inc. Aspiration and injection device
CN105999259A (zh) * 2016-05-11 2016-10-12 长春海基亚生物技术股份有限公司 无针注射狂犬病疫苗系统与应用
US20200306518A1 (en) 2016-05-20 2020-10-01 Uprax Microsolutions B.V. System and method for applying microneedles
MX389702B (es) 2016-06-22 2025-03-20 Ellipses Pharma Ltd Compuestos para usarse en el tratamiento de cancer de mama que expresa el receptor de androgenos (ar+).
CN121588347A (zh) * 2016-12-16 2026-03-03 索伦托治疗有限公司 用于流体递送装置的施用机构及其使用方法
US11141576B2 (en) 2016-12-20 2021-10-12 Hisamitsu Pharmaceutical Co., Inc. Applicator for applying a sheet member to skin
JP7481115B2 (ja) 2017-01-05 2024-05-10 ラジウス ファーマシューティカルズ,インコーポレイテッド Rad1901-2hclの多形性形態
WO2018139504A1 (ja) 2017-01-25 2018-08-02 コスメディ製薬株式会社 マイクロニードルパッチ適用装置
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
ES2960937T3 (es) 2017-03-31 2024-03-07 Vaxxas Pty Ltd Dispositivo y método para recubrir superficies
JP2018191783A (ja) * 2017-05-15 2018-12-06 富士フイルム株式会社 マイクロニードルアレイユニット、および容器
US11175128B2 (en) 2017-06-13 2021-11-16 Vaxxas Pty Limited Quality control of substrate coatings
EP4473998A3 (de) 2017-08-04 2025-02-26 Vaxxas Pty Limited Kompakter hoher mechanischer energiespeicher und aktuator mit geringer auslösekraft für die abgabe von mikroprojektions-array-patches (map)
US10430138B2 (en) * 2017-08-10 2019-10-01 Canon Kabushiki Kaisha Communication apparatus
EP3672570A1 (de) 2017-08-23 2020-07-01 Zosano Pharma Corporation Verfahren zur schnellen erreichung therapeutischer konzentrationen von zolmitriptan zur behandlung von migräne und cluster-kopfschmerzen
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
WO2019077519A1 (en) 2017-10-17 2019-04-25 3M Innovative Properties Company APPLICATOR FOR APPLYING A SKIN INJECTION CHIP
JP7033886B2 (ja) * 2017-11-07 2022-03-11 ニプロ株式会社 穿刺用器具
KR20200100710A (ko) * 2017-12-19 2020-08-26 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로 어레이 어플리케이터
CA3089513A1 (en) 2018-01-24 2019-08-01 Cosmed Pharmaceutical Co., Ltd. Tight-binding device for micro-needle
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
MX2020013713A (es) 2018-07-04 2021-03-02 Radius Pharmaceuticals Inc Formas polimorficas de rad1901-2hcl.
JP7099189B2 (ja) * 2018-08-30 2022-07-12 ニプロ株式会社 マイクロニードルアプリケータ
JP7172293B2 (ja) * 2018-08-30 2022-11-16 ニプロ株式会社 マイクロニードルアプリケータ
WO2020045588A1 (ja) * 2018-08-30 2020-03-05 ニプロ株式会社 マイクロニードルアプリケータ
US11246997B2 (en) * 2018-09-25 2022-02-15 Palo Alto Research Center Incorporated Handheld filament extension atomizer for precision delivery of drugs and therapeutics
CN109364364B (zh) * 2018-12-10 2021-06-22 徐爱梅 一种皮肤科涂药装置
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
EP3924328A1 (de) 2019-02-12 2021-12-22 Radius Pharmaceuticals, Inc. Verfahren und verbindungen
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ2
ES3001447T3 (en) 2019-06-25 2025-03-05 William Ma Sheathed cutting device
JP2022546459A (ja) * 2019-08-27 2022-11-04 エルテーエス ローマン テラピー-ジステーメ アーゲー マイクロアレイアプリケータ、及び、マイクロアレイに作用するプランジャを移動させるための方法
CN111685867B (zh) * 2020-06-22 2020-12-01 镇江恒生涓恩医疗器械有限公司 一种多级稳定型消融电极
EP3974017A1 (de) * 2020-09-28 2022-03-30 Latch Medical System zur anwendung eines mikronadel-patch
CN114748778B (zh) * 2021-01-11 2024-05-03 苏州纳生微电子有限公司 传动结构、应用传动结构的给液装置及其使用方法
US11654270B2 (en) 2021-09-28 2023-05-23 Biolinq Incorporated Microneedle enclosure and applicator device for microneedle array based continuous analyte monitoring device
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
USD1057153S1 (en) 2022-04-29 2025-01-07 Biolinq Incorporated Microneedle array sensor applicator device
WO2024097385A1 (en) * 2022-11-05 2024-05-10 Kindeva Drug Delivery L.P. Microneedle array applicator and system
CN119345590B (zh) * 2024-11-06 2025-09-19 中国人民解放军空军军医大学 一种可溶性微针治疗装置

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3136314A (en) * 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
GB2064329B (en) * 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) * 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4553541A (en) * 1981-03-23 1985-11-19 Becton, Dickinson And Co. Automatic retractable lancet assembly
EP0429842B1 (de) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
FR2696334B1 (fr) * 1992-10-01 1994-12-02 Boudjema J Pascal Dispositif pour transplantation de greffons capillaires de petit diamètre.
US5439473A (en) * 1993-12-13 1995-08-08 Modulohm A/S Safety lancet
US5350392A (en) * 1994-02-03 1994-09-27 Miles Inc. Lancing device with automatic cocking
US5487726A (en) * 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
JPH10510175A (ja) 1994-12-09 1998-10-06 ノバルティス アクチェンゲゼルシャフト 経皮システム
WO1996037155A1 (en) 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
DE19758959B8 (de) 1996-05-17 2013-08-01 Roche Diagnostics Operations Inc. (N.D.Ges.D.Staates Delaware) Vorrichtung zum Ausdrücken von Körperflüssigkeiten aus einem Einstich
CA2253549C (en) 1996-06-18 2005-10-25 Alza Corporation Device for enhancing transdermal agent delivery or sampling
ATE241405T1 (de) 1996-07-03 2003-06-15 Altea Therapeutics Corp Mehrfache mechanische mikroperforierung von haut oder schleimhäuten
US5983136A (en) 1996-09-17 1999-11-09 Deka Products Limited Partnership System for delivery of drugs by transport
EP0957972B1 (de) 1996-12-20 2003-03-19 Alza Corporation Vorrichtung und verfahren zur erhöhung des transdermalen wirkstoffeflusses
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
BR9714113A (pt) 1996-12-31 2000-03-21 Shell Int Research Plataforma de tirante
US5964718A (en) 1997-11-21 1999-10-12 Mercury Diagnostics, Inc. Body fluid sampling device
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
DE69806963T2 (de) 1997-12-11 2002-11-21 Alza Corp., Mountain View Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
CA2313698C (en) 1997-12-11 2008-04-15 Alza Corporation Device for enhancing transdermal agent flux
ES2314995T3 (es) 1997-12-11 2009-03-16 Alza Corporation Dispositivo para mejorar el flujo de agentes tansdermicos.
EP1086214B1 (de) 1998-06-10 2009-11-25 Georgia Tech Research Corporation Mikronadel-einrichtungen und verfahren zur deren herstellung
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6248120B1 (en) * 2000-01-10 2001-06-19 P. Z. “HTL” Spolka Akcyjna Puncturing device
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6533949B1 (en) * 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
PL360978A1 (en) 2000-10-13 2004-09-20 Alza Corporation Microblade array impact applicator
ATE416692T1 (de) 2000-10-13 2008-12-15 Alza Corp Mikronadelelementhalter für schlagapplikator
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
DE60138411D1 (de) * 2000-10-13 2009-05-28 Alza Corp Vorrichtung und verfahren zum durchstechen der haut mit micronadeln
NZ525551A (en) 2000-10-26 2005-09-30 Alza Corp Transdermal drug delivery devices having coated microprotrusions
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
ATE444773T1 (de) 2001-04-20 2009-10-15 Alza Corp Mikroprojektionsanordnung mit einem überzug, der ein vorteilhaftes mittel enthält
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US20030199810A1 (en) 2001-11-30 2003-10-23 Trautman Joseph Creagan Methods and apparatuses for forming microprojection arrays
WO2003053258A1 (en) 2001-12-20 2003-07-03 Alza Corporation Skin-piercing microprojections having piercing depth control
WO2003074102A2 (en) * 2002-03-04 2003-09-12 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
AU2003279641B2 (en) 2002-06-28 2009-06-18 Alza Corporation Transdermal drug delivery devices having coated microprotrusions
CN102872526A (zh) * 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
AR042815A1 (es) 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
KR20060038407A (ko) 2003-06-30 2006-05-03 알자 코포레이션 비휘발성 반대이온을 포함하는 코팅된 미세돌출부용 제제
US20050123507A1 (en) 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
JP2007535337A (ja) 2003-10-28 2007-12-06 アルザ・コーポレーシヨン 被覆された微小突起による治療用ペプチドおよびタンパクのポリマー接合体の送達
ES2377647T3 (es) 2003-10-31 2012-03-29 Alza Corporation Aplicador auto-actuado para ordenamiento de microproyecciones
KR20070010115A (ko) 2003-11-13 2007-01-22 알자 코포레이션 경피전달용 조성물 및 장치
US7556821B2 (en) 2004-05-13 2009-07-07 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
CA2593112A1 (en) 2005-01-21 2006-07-27 Alza Corporation Therapeutic peptide formulations for coating microneedles with improved stability containing at least one counterion
TW200700094A (en) 2005-01-31 2007-01-01 Alza Corp Coated microprojections having reduced variability and method for producing same
CA2596120A1 (en) 2005-02-16 2006-08-24 Alza Corporation Microprojection arrays with improved biocompatibility
US20060275170A1 (en) 2005-06-02 2006-12-07 Mahmoud Ameri Method for terminal sterilization of transdermal delivery devices
EP1898989A2 (de) 2005-06-21 2008-03-19 Alza Corporation Verfahren und vorrichtung zur beschichtung eines kontinuierlichen bandes mit mikroprojektionselementen

Also Published As

Publication number Publication date
JP2007509706A (ja) 2007-04-19
US20050096586A1 (en) 2005-05-05
WO2005044333A3 (en) 2006-06-01
AU2004287414B2 (en) 2010-11-25
CN1901840A (zh) 2007-01-24
TW200633675A (en) 2006-10-01
JP4682144B2 (ja) 2011-05-11
US20070027427A1 (en) 2007-02-01
US9421351B2 (en) 2016-08-23
CN100571643C (zh) 2009-12-23
EP1680154A4 (de) 2007-07-18
ES2377647T3 (es) 2012-03-29
BRPI0415629A (pt) 2006-12-12
EP1680154B1 (de) 2012-01-04
CA2543641A1 (en) 2005-05-19
WO2005044333A2 (en) 2005-05-19
EP1680154A2 (de) 2006-07-19
KR20060099523A (ko) 2006-09-19
AU2004287414A1 (en) 2005-05-19
US7097631B2 (en) 2006-08-29
AR046696A1 (es) 2005-12-21

Similar Documents

Publication Publication Date Title
ATE539687T1 (de) Selbstbetätigter applikator für eine mikroprojektionsanordnung
DE60332690D1 (de) Bodenkonstruktion für eine Flasche
DE60318543D1 (de) Handgriffanordnung für eine Biopsievorrichtung
DE602004019033D1 (de) Sicherheitseinrichtung für eine Spritzvorrichtung
FR2890544B1 (fr) Applicateur
IS2693B (is) Fenoxýediksýruafleiður
NO20052047D0 (no) Informasjonsplukker
DE602004024808D1 (de) System für die abgabe einer substanz in eine körperhöhle
EP1678423A4 (de) Mikropumpe
DE60229725D1 (de) Kühlschrank für Kosmetik
ATE418924T1 (de) Marknagel
ATE462365T1 (de) Marknagel
EP1666210A4 (de) Nagelmaschine
ATA1522003A (de) Sperrvorrichtung für eine pistole
EP1542745A4 (de) Hülle für eine nadelanordnung
DE50305992D1 (de) Gassack für eine insassenschutzeinrichtung
DE602004000935D1 (de) Kosmetikapplikator
ATE375761T1 (de) Marknagel
DE602004002443D1 (de) Lagerung für eine Antriebseinheit
DE50301987D1 (de) Auftraggerät
DE602004031650D1 (de) Drehbund für hubsäge
DE502004006279D1 (de) Einsatzwerkzeug für eine werkzeugmaschine
FR2860402B1 (fr) Applicateur multiple
DE502004008685D1 (de) Fadenführervorrichtung für ringspindel
DE602004023406D1 (de) Steuerverfahren für eine lichtempfindliche einrichtung