ATE540048T1 - Neurotransmittersensoren und verfahren zu ihrer verwendung - Google Patents

Neurotransmittersensoren und verfahren zu ihrer verwendung

Info

Publication number
ATE540048T1
ATE540048T1 AT05812420T AT05812420T ATE540048T1 AT E540048 T1 ATE540048 T1 AT E540048T1 AT 05812420 T AT05812420 T AT 05812420T AT 05812420 T AT05812420 T AT 05812420T AT E540048 T1 ATE540048 T1 AT E540048T1
Authority
AT
Austria
Prior art keywords
neurotransmitter
biosensors
binding
detection
sensors
Prior art date
Application number
AT05812420T
Other languages
English (en)
Inventor
Sakiko Okumoto
Loren Looger
Wolf Frommer
Original Assignee
Carnegie Inst Of Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carnegie Inst Of Washington filed Critical Carnegie Inst Of Washington
Application granted granted Critical
Publication of ATE540048T1 publication Critical patent/ATE540048T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9406—Neurotransmitters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
AT05812420T 2004-10-14 2005-10-14 Neurotransmittersensoren und verfahren zu ihrer verwendung ATE540048T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US61817904P 2004-10-14 2004-10-14
US64357605P 2005-01-14 2005-01-14
PCT/US2005/036956 WO2006044611A2 (en) 2004-10-14 2005-10-14 Neurotransmitter sensors and methods of using the same

Publications (1)

Publication Number Publication Date
ATE540048T1 true ATE540048T1 (de) 2012-01-15

Family

ID=36203531

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05812420T ATE540048T1 (de) 2004-10-14 2005-10-14 Neurotransmittersensoren und verfahren zu ihrer verwendung

Country Status (8)

Country Link
US (2) US7777016B2 (de)
EP (1) EP1805200B1 (de)
JP (2) JP2008516606A (de)
AT (1) ATE540048T1 (de)
AU (1) AU2005295655A1 (de)
CA (1) CA2584116A1 (de)
IL (1) IL182487A0 (de)
WO (1) WO2006044611A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1815246A4 (de) * 2004-10-14 2009-12-16 Carnegie Inst Of Washington Entwicklung von empfindlichen fret-sensoren und verwendungsverfahren dafür
US20060257934A1 (en) * 2005-04-19 2006-11-16 Svetlana Tertyshnikova Cell-based assay for the quantitative high throughput screening of gamma-aminobutyric acid-induced halide transport
CA2625169A1 (en) * 2005-10-14 2007-04-26 Carnegie Institution Of Washington Methods of reducing repeat-induced silencing of transgene expression and improved fluorescent biosensors
US20120122115A1 (en) * 2006-04-25 2012-05-17 Sayre Richard T Bacterial quorum sensing biosensor
WO2009023153A1 (en) * 2007-08-10 2009-02-19 Carnegie Institution Of Washington Methods of using ret nanosensors
JP5349016B2 (ja) * 2008-11-20 2013-11-20 日本電信電話株式会社 膜タンパク質機能測定基板及び膜タンパク質機能測定方法
KR102307241B1 (ko) * 2018-12-05 2021-09-29 성균관대학교산학협력단 푸코실락토오스 검출용 바이오센서 및 이를 이용하여 푸코실락토오스의 정량 분석 방법
CN119409840B (zh) * 2025-01-06 2025-07-01 北京大学 基于g蛋白偶联受体构建的比率型荧光探针及其构建方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6803188B1 (en) * 1996-01-31 2004-10-12 The Regents Of The University Of California Tandem fluorescent protein constructs
US5795729A (en) * 1996-02-05 1998-08-18 Biometric Imaging, Inc. Reductive, energy-transfer fluorogenic probes
US6084084A (en) * 1996-02-21 2000-07-04 Nps Pharmaceuticals, Inc. Human metabotropic glutamate receptor
US5998204A (en) * 1997-03-14 1999-12-07 The Regents Of The University Of California Fluorescent protein sensors for detection of analytes
US6376257B1 (en) * 1997-04-24 2002-04-23 University Of Rochester Detection by fret changes of ligand binding by GFP fusion proteins
EP1044374B1 (de) * 1997-12-31 2008-10-08 Duke University Glukosebiosensor
AU759888B2 (en) * 1998-07-17 2003-05-01 University Of Maryland At Baltimore Engineered proteins for analyte sensing
WO2000049183A1 (en) 1999-02-17 2000-08-24 Clontech Laboratories, Inc. FLUORESCENCE RESONANCE ENERGY TRANSFER DETECTION OF cAMP IN LIVING CELLS USING GFP VARIANTS
US6465199B1 (en) * 1999-02-26 2002-10-15 Cyclacel, Ltd. Compositions and methods for monitoring the modification of natural binding partners
US6469154B1 (en) * 1999-05-21 2002-10-22 The Regents Of The University Of California Fluorescent protein indicators
CA2314398A1 (en) * 2000-08-10 2002-02-10 Edward Shipwash Microarrays and microsystems for amino acid analysis and protein sequencing
US7687614B2 (en) * 2001-02-26 2010-03-30 The Regents Of The University Of California Monomeric and dimeric fluorescent protein variants and methods for making same
EP2284195A1 (de) * 2001-09-18 2011-02-16 Carnegie Institution Of Washington Fusionsproteine zur Detektion von Analyten
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
US6855556B2 (en) * 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
US9625458B2 (en) * 2002-10-16 2017-04-18 Duke University Biosensor
EP1595129A4 (de) * 2003-01-17 2009-03-04 Univ Johns Hopkins Verfahren zur identifizierung von zellglykosylierungsmodulatoren unter verwendung von gtrap3-18
US20050112685A1 (en) * 2003-11-26 2005-05-26 Amiss Terry J. Compositions and methods for measuring analyte concentrations

Also Published As

Publication number Publication date
AU2005295655A1 (en) 2006-04-27
US20110289609A1 (en) 2011-11-24
WO2006044611A2 (en) 2006-04-27
JP2008516606A (ja) 2008-05-22
CA2584116A1 (en) 2006-04-27
US7777016B2 (en) 2010-08-17
WO2006044611A3 (en) 2007-02-22
US8354250B2 (en) 2013-01-15
EP1805200A4 (de) 2008-07-02
EP1805200A2 (de) 2007-07-11
JP2013059335A (ja) 2013-04-04
IL182487A0 (en) 2007-09-20
EP1805200B1 (de) 2012-01-04
US20080019920A1 (en) 2008-01-24

Similar Documents

Publication Publication Date Title
IL182487A0 (en) Neurotransmitter sensors and methods using the same
ATE514755T1 (de) Fluoreszenzfarbstoffe zur verwendung bei der glukoseerfassung
DE602008006382D1 (de) Pyridin-boronsäure-quencher zur verwendung in analytsensoren
ATE425266T1 (de) Aptamer-nanopartikelkonjugate und verwendungsverfahren zur detektion von zielanalyten
EP1692486A4 (de) Biosensoren zum nachweis von makromolekülen und anderen analyten
EP1671118A4 (de) Cyanid wahrnehmende verbindungen und verwendungen davon
EP2312317A3 (de) Fluoreszentes Erkennungssystem und Farbstoffsatz zur Verwendung damit
DK2018441T3 (da) Mærkede mikroorganismer og fremgangsmåde til mærkning
EP2189519A4 (de) Zellkulturinstrument und zellkuklturverfahren damit
NZ596163A (en) Diagnostic devices and related methods
EP2376906A4 (de) Verfahren zur signalverstärkung bei einem immunchromatographietest sowie immunchromatographie-kit mit verwendung des verfahrens
EP2259061A3 (de) Boronsäure Derivaten
IN2012DN03156A (de)
EP2037272A4 (de) Kit und verfahren zum nachweis bzw. zur quantifizierung eines analyten
WO2007059297A8 (en) Multimeric biosensors and methods of using the same
IL190706A0 (en) Isolated nucleic acid which encodes a sucrose fluorescent indicator, sucrose biosensors and methods of using the same
WO2008103319A3 (en) Compounds and methods for use in detecting gabapentin
WO2007050979A3 (en) Real time nucleic acid detection in vivo using protein complementation
WO2008108873A3 (en) Molecular biosensors for detecting macromolecules and other analytes
DK1800136T3 (da) Kompetitiv differentiel screening
WO2007098336A3 (en) Compounds and methods for fluorescent labeling
ATE456666T1 (de) Verfahren zur auswertung von ribonukleotidsequenzen
IL190707A0 (en) Isolated nucleic acid which encodes a phosphate fluorescent indicator, phosphate biosensors and methods of using the same
ATE511636T1 (de) Verfahren zum nachweis biologischer organismen mittels raman-streuung
WO2007021757A3 (en) Fluorescent sensor and methods