ATE540965T1 - Ob-rezeptor und verfahren zur diagnose und behandlung von gewicht - Google Patents

Ob-rezeptor und verfahren zur diagnose und behandlung von gewicht

Info

Publication number: ATE540965T1
Authority: AT; Austria
Prior art keywords: obr; receptor; diagnosis; express; nucleotides
Prior art date: 1995-11-27

Application number

AT96942110T

Other languages

English (en)

Inventor

Louis A Tartaglia

Robert Tepper

Janice Culpepper

David White

Original Assignee

Millennium Pharm Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-27

Filing date

1996-11-27

Publication date

2012-01-15

1995-12-28 Priority claimed from US08/583,153 external-priority patent/US6506877B1/en

1996-01-22 Priority claimed from US08/599,455 external-priority patent/US5972621A/en

1996-04-26 Priority claimed from US08/638,524 external-priority patent/US6548269B1/en

1996-09-03 Priority claimed from US08/708,123 external-priority patent/US6482927B1/en

1996-11-27 Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc

2012-01-15 Application granted granted Critical

2012-01-15 Publication of ATE540965T1 publication Critical patent/ATE540965T1/de

Links

238000003745 diagnosis Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
108020003175 receptors Proteins 0.000 abstract 4
102000005962 receptors Human genes 0.000 abstract 4
241001465754 Metazoa Species 0.000 abstract 2
230000014509 gene expression Effects 0.000 abstract 2
239000002773 nucleotide Substances 0.000 abstract 2
125000003729 nucleotide group Chemical group 0.000 abstract 2
102000004196 processed proteins & peptides Human genes 0.000 abstract 2
108090000765 processed proteins & peptides Proteins 0.000 abstract 2
206010006895 Cachexia Diseases 0.000 abstract 1
208000008589 Obesity Diseases 0.000 abstract 1
108700019146 Transgenes Proteins 0.000 abstract 1
239000000556 agonist Substances 0.000 abstract 1
208000022531 anorexia Diseases 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
230000037396 body weight Effects 0.000 abstract 1
230000006583 body weight regulation Effects 0.000 abstract 1
238000012512 characterization method Methods 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
206010061428 decreased appetite Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
208000035475 disorder Diseases 0.000 abstract 1
238000007877 drug screening Methods 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
108020001507 fusion proteins Proteins 0.000 abstract 1
102000037865 fusion proteins Human genes 0.000 abstract 1
238000012544 monitoring process Methods 0.000 abstract 1
235000020824 obesity Nutrition 0.000 abstract 1
229920001184 polypeptide Polymers 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
230000009261 transgenic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Toxicology (AREA)
Immunology (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Zoology (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Cell Biology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

AT96942110T 1995-11-27 1996-11-27 Ob-rezeptor und verfahren zur diagnose und behandlung von gewicht ATE540965T1 (de)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
US56266395A	1995-11-27	1995-11-27
US56662295A	1995-12-04	1995-12-04
US56948595A	1995-12-08	1995-12-08
US08/570,142 US6509189B1 (en)	1995-11-27	1995-12-11	Nucleic acid molecules encoding the cytoplasmic domain of human Ob receptor
US08/583,153 US6506877B1 (en)	1995-11-27	1995-12-28	Ob receptor
US08/599,455 US5972621A (en)	1995-11-27	1996-01-22	Methods of identifying compounds that modulate body weight using the OB receptor
US08/638,524 US6548269B1 (en)	1995-11-27	1996-04-26	Ob receptor and methods for the diagnosis and treatment of body weight disorders, including obesity and cachexia
US08/708,123 US6482927B1 (en)	1995-11-27	1996-09-03	Chimeric proteins comprising the extracellular domain of murine Ob receptor
PCT/US1996/019128 WO1997019952A1 (en)	1995-11-27	1996-11-27	The ob receptor and methods of diagnosing and treating weight

Publications (1)

Publication Number	Publication Date
ATE540965T1 true ATE540965T1 (de)	2012-01-15

Family

ID=27415891

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT96942110T ATE540965T1 (de)	1995-11-27	1996-11-27	Ob-rezeptor und verfahren zur diagnose und behandlung von gewicht

Country Status (2)

Country	Link
US (1)	US6509189B1 (de)
AT (1)	ATE540965T1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060161148A1 (en) *	2005-01-13	2006-07-20	Robert Behnke	Circuit and method for controlling an electrosurgical generator using a full bridge topology
JP2008289483A (ja) *	2007-05-25	2008-12-04	Symphogen As	真核生物系において発現可能な形質転換体のスクリーニング
TWI543792B (zh) *	2012-12-28	2016-08-01	Metal Ind Res & Dev Ct	Tissue injection of heat therapy needle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5763211A (en) *	1994-09-14	1998-06-09	Progenitor, Inc.	Isolated nucleic acid encoding Hu-B1.219, a novel human hematopoietin
US5643748A (en)	1994-09-14	1997-07-01	Progenitor, Inc.	HU-B1.219, a novel human hematopoietin receptor
US5856098A (en) *	1994-09-14	1999-01-05	Progenitor, Inc.	Detection of a leptin receptor variant

1995
- 1995-12-11 US US08/570,142 patent/US6509189B1/en not_active Expired - Fee Related
1996
- 1996-11-27 AT AT96942110T patent/ATE540965T1/de active

Also Published As

Publication number	Publication date
US6509189B1 (en)	2003-01-21

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