DK0948536T3 - G-protein-koblet receptor med et forstörret extracellulært domæne - Google Patents
G-protein-koblet receptor med et forstörret extracellulært domæneInfo
- Publication number
- DK0948536T3 DK0948536T3 DK97905736T DK97905736T DK0948536T3 DK 0948536 T3 DK0948536 T3 DK 0948536T3 DK 97905736 T DK97905736 T DK 97905736T DK 97905736 T DK97905736 T DK 97905736T DK 0948536 T3 DK0948536 T3 DK 0948536T3
- Authority
- DK
- Denmark
- Prior art keywords
- receptor
- diseases
- coupled receptor
- protein
- extracellular domain
- Prior art date
Links
- 102000003688 G-Protein-Coupled Receptors Human genes 0.000 title abstract 3
- 108090000045 G-Protein-Coupled Receptors Proteins 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 102000005962 receptors Human genes 0.000 abstract 3
- 108020003175 receptors Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000002216 heart Anatomy 0.000 abstract 1
- 210000003958 hematopoietic stem cell Anatomy 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 210000004072 lung Anatomy 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 210000002826 placenta Anatomy 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000003827 upregulation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
- C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1080896P | 1996-01-30 | 1996-01-30 | |
| PCT/US1997/001736 WO1997028188A1 (en) | 1996-01-30 | 1997-01-30 | A g protein-coupled receptor with an enlarged extracellular domain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0948536T3 true DK0948536T3 (da) | 2007-10-01 |
Family
ID=21747533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97905736T DK0948536T3 (da) | 1996-01-30 | 1997-01-30 | G-protein-koblet receptor med et forstörret extracellulært domæne |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6521418B1 (da) |
| EP (1) | EP0948536B1 (da) |
| AT (1) | ATE364627T1 (da) |
| AU (1) | AU733853B2 (da) |
| CA (1) | CA2244850A1 (da) |
| DE (1) | DE69737815T2 (da) |
| DK (1) | DK0948536T3 (da) |
| ES (1) | ES2287951T3 (da) |
| WO (1) | WO1997028188A1 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH1087700A (ja) * | 1996-06-17 | 1998-04-07 | Smithkline Beecham Corp | C3a受容体およびC3aを用いる治療およびスクリーニング方法 |
| WO2000078950A2 (en) * | 1999-06-22 | 2000-12-28 | Amylin Pharmaceuticals, Inc. | Differentially expressed genes in the adipocytes of obese mice |
| CA2416292A1 (en) * | 2000-06-29 | 2002-01-10 | Deltagen, Inc. | Transgenic mice containing targeted gene disruptions |
| AUPS271902A0 (en) * | 2002-05-31 | 2002-06-20 | Griffith University | Gene expression and multiple sclerosis |
| AU2003276653A1 (en) * | 2002-06-13 | 2003-12-31 | New England Medical Center Hospitals, Inc. | Rapid methods for assessing therapeutic activity using animals expressing constitutively active g protein-coupled receptors |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| WO2004082566A2 (en) * | 2003-03-17 | 2004-09-30 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with complement component 3a receptor 1 (c3ar1) |
| US20060068426A1 (en) * | 2004-08-20 | 2006-03-30 | Tam James P | Cyclic peptides and antibodies thereof |
| RU2432362C2 (ru) | 2005-11-30 | 2011-10-27 | Эбботт Лэборетриз | Моноклональные антитела и их применения |
| PL2289909T3 (pl) | 2005-11-30 | 2015-04-30 | Abbvie Inc | Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| EP2124952A2 (en) | 2007-02-27 | 2009-12-02 | Abbott GmbH & Co. KG | Method for the treatment of amyloidoses |
| ES2684475T3 (es) | 2010-04-15 | 2018-10-03 | Abbvie Inc. | Proteínas que se unen a beta amiloide |
| CN103298833B (zh) | 2010-08-14 | 2015-12-16 | Abbvie公司 | β淀粉样蛋白结合蛋白 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030027245A1 (en) * | 1995-02-17 | 2003-02-06 | Yi Li | Human g-protein coupled receptor |
| AU1921695A (en) * | 1995-02-17 | 1996-09-04 | Human Genome Sciences, Inc. | Human g-protein coupled receptor |
| JPH11507513A (ja) * | 1995-06-05 | 1999-07-06 | インサイト・ファーマスーティカルズ・インコーポレイテッド | C5a様7膜貫通受容体 |
| JPH1087700A (ja) * | 1996-06-17 | 1998-04-07 | Smithkline Beecham Corp | C3a受容体およびC3aを用いる治療およびスクリーニング方法 |
-
1997
- 1997-01-30 AT AT97905736T patent/ATE364627T1/de not_active IP Right Cessation
- 1997-01-30 DE DE69737815T patent/DE69737815T2/de not_active Expired - Fee Related
- 1997-01-30 AU AU22560/97A patent/AU733853B2/en not_active Ceased
- 1997-01-30 DK DK97905736T patent/DK0948536T3/da active
- 1997-01-30 WO PCT/US1997/001736 patent/WO1997028188A1/en not_active Ceased
- 1997-01-30 US US09/117,440 patent/US6521418B1/en not_active Expired - Fee Related
- 1997-01-30 ES ES97905736T patent/ES2287951T3/es not_active Expired - Lifetime
- 1997-01-30 CA CA002244850A patent/CA2244850A1/en not_active Abandoned
- 1997-01-30 EP EP97905736A patent/EP0948536B1/en not_active Expired - Lifetime
-
2003
- 2003-02-14 US US10/367,035 patent/US20030187244A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP0948536A4 (en) | 2001-04-11 |
| DE69737815D1 (de) | 2007-07-26 |
| WO1997028188A1 (en) | 1997-08-07 |
| AU2256097A (en) | 1997-08-22 |
| US6521418B1 (en) | 2003-02-18 |
| AU733853B2 (en) | 2001-05-31 |
| EP0948536A1 (en) | 1999-10-13 |
| DE69737815T2 (de) | 2008-03-06 |
| CA2244850A1 (en) | 1997-08-07 |
| ATE364627T1 (de) | 2007-07-15 |
| US20030187244A1 (en) | 2003-10-02 |
| EP0948536B1 (en) | 2007-06-13 |
| ES2287951T3 (es) | 2007-12-16 |
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