DK0948536T3 - G-protein-koblet receptor med et forstörret extracellulært domæne - Google Patents

G-protein-koblet receptor med et forstörret extracellulært domæne

Info

Publication number
DK0948536T3
DK0948536T3 DK97905736T DK97905736T DK0948536T3 DK 0948536 T3 DK0948536 T3 DK 0948536T3 DK 97905736 T DK97905736 T DK 97905736T DK 97905736 T DK97905736 T DK 97905736T DK 0948536 T3 DK0948536 T3 DK 0948536T3
Authority
DK
Denmark
Prior art keywords
receptor
diseases
coupled receptor
protein
extracellular domain
Prior art date
Application number
DK97905736T
Other languages
English (en)
Inventor
Richard D Ye
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK0948536T3 publication Critical patent/DK0948536T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK97905736T 1996-01-30 1997-01-30 G-protein-koblet receptor med et forstörret extracellulært domæne DK0948536T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1080896P 1996-01-30 1996-01-30
PCT/US1997/001736 WO1997028188A1 (en) 1996-01-30 1997-01-30 A g protein-coupled receptor with an enlarged extracellular domain

Publications (1)

Publication Number Publication Date
DK0948536T3 true DK0948536T3 (da) 2007-10-01

Family

ID=21747533

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97905736T DK0948536T3 (da) 1996-01-30 1997-01-30 G-protein-koblet receptor med et forstörret extracellulært domæne

Country Status (9)

Country Link
US (2) US6521418B1 (da)
EP (1) EP0948536B1 (da)
AT (1) ATE364627T1 (da)
AU (1) AU733853B2 (da)
CA (1) CA2244850A1 (da)
DE (1) DE69737815T2 (da)
DK (1) DK0948536T3 (da)
ES (1) ES2287951T3 (da)
WO (1) WO1997028188A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1087700A (ja) * 1996-06-17 1998-04-07 Smithkline Beecham Corp C3a受容体およびC3aを用いる治療およびスクリーニング方法
WO2000078950A2 (en) * 1999-06-22 2000-12-28 Amylin Pharmaceuticals, Inc. Differentially expressed genes in the adipocytes of obese mice
CA2416292A1 (en) * 2000-06-29 2002-01-10 Deltagen, Inc. Transgenic mice containing targeted gene disruptions
AUPS271902A0 (en) * 2002-05-31 2002-06-20 Griffith University Gene expression and multiple sclerosis
AU2003276653A1 (en) * 2002-06-13 2003-12-31 New England Medical Center Hospitals, Inc. Rapid methods for assessing therapeutic activity using animals expressing constitutively active g protein-coupled receptors
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
WO2004082566A2 (en) * 2003-03-17 2004-09-30 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with complement component 3a receptor 1 (c3ar1)
US20060068426A1 (en) * 2004-08-20 2006-03-30 Tam James P Cyclic peptides and antibodies thereof
RU2432362C2 (ru) 2005-11-30 2011-10-27 Эбботт Лэборетриз Моноклональные антитела и их применения
PL2289909T3 (pl) 2005-11-30 2015-04-30 Abbvie Inc Sposób przeszukiwania, proces oczyszczania niedyfundujących oligomerów Abeta, selektywne przeciwciała przeciw niedyfundującym oligomerom Abeta i sposób wytwarzania tych przeciwciał
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
EP2124952A2 (en) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Method for the treatment of amyloidoses
ES2684475T3 (es) 2010-04-15 2018-10-03 Abbvie Inc. Proteínas que se unen a beta amiloide
CN103298833B (zh) 2010-08-14 2015-12-16 Abbvie公司 β淀粉样蛋白结合蛋白

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030027245A1 (en) * 1995-02-17 2003-02-06 Yi Li Human g-protein coupled receptor
AU1921695A (en) * 1995-02-17 1996-09-04 Human Genome Sciences, Inc. Human g-protein coupled receptor
JPH11507513A (ja) * 1995-06-05 1999-07-06 インサイト・ファーマスーティカルズ・インコーポレイテッド C5a様7膜貫通受容体
JPH1087700A (ja) * 1996-06-17 1998-04-07 Smithkline Beecham Corp C3a受容体およびC3aを用いる治療およびスクリーニング方法

Also Published As

Publication number Publication date
EP0948536A4 (en) 2001-04-11
DE69737815D1 (de) 2007-07-26
WO1997028188A1 (en) 1997-08-07
AU2256097A (en) 1997-08-22
US6521418B1 (en) 2003-02-18
AU733853B2 (en) 2001-05-31
EP0948536A1 (en) 1999-10-13
DE69737815T2 (de) 2008-03-06
CA2244850A1 (en) 1997-08-07
ATE364627T1 (de) 2007-07-15
US20030187244A1 (en) 2003-10-02
EP0948536B1 (en) 2007-06-13
ES2287951T3 (es) 2007-12-16

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