ATE541050T1 - Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips - Google Patents
Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochipsInfo
- Publication number
- ATE541050T1 ATE541050T1 AT03104367T AT03104367T ATE541050T1 AT E541050 T1 ATE541050 T1 AT E541050T1 AT 03104367 T AT03104367 T AT 03104367T AT 03104367 T AT03104367 T AT 03104367T AT E541050 T1 ATE541050 T1 AT E541050T1
- Authority
- AT
- Austria
- Prior art keywords
- fluorescence
- analysis
- target molecules
- biological target
- fluorescence marker
- Prior art date
Links
- 238000000018 DNA microarray Methods 0.000 title 1
- 238000004458 analytical method Methods 0.000 title 1
- 239000003550 marker Substances 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 5
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 5
- 230000000295 complement effect Effects 0.000 abstract 1
- 239000007850 fluorescent dye Substances 0.000 abstract 1
- 238000003908 quality control method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00497—Features relating to the solid phase supports
- B01J2219/00527—Sheets
- B01J2219/00529—DNA chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
- B01J2219/00576—Chemical means fluorophore
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00608—DNA chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00693—Means for quality control
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Optical Measuring Cells (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0002236A FR2805348B1 (fr) | 2000-02-23 | 2000-02-23 | Analyse de cibles biologiques utilisant une biopuce comportant un marqueur fluorescent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE541050T1 true ATE541050T1 (de) | 2012-01-15 |
Family
ID=8847290
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01907873T ATE275641T1 (de) | 2000-02-23 | 2001-02-22 | Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips |
| AT03104367T ATE541050T1 (de) | 2000-02-23 | 2001-02-22 | Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01907873T ATE275641T1 (de) | 2000-02-23 | 2001-02-22 | Analyse von biologischen zielmolekülen unter verwendung eines einen fluoreszenzmarker tragenden biochips |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6861515B2 (de) |
| EP (2) | EP1413630B1 (de) |
| JP (1) | JP4729226B2 (de) |
| AT (2) | ATE275641T1 (de) |
| AU (1) | AU2001235742A1 (de) |
| CA (1) | CA2399258A1 (de) |
| DE (1) | DE60105399T2 (de) |
| FR (1) | FR2805348B1 (de) |
| WO (1) | WO2001063282A2 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1278889B1 (de) * | 2000-03-29 | 2006-07-26 | LGC Limited | Hybridisierungsprobe und methode zum schnellen nachweis und zur schnellen unterscheidung von sequenzen |
| AU2002255771B2 (en) | 2001-03-16 | 2007-10-18 | Qtl Biosystems, Llc | Fluorescent polymer superquenching-based bioassays |
| FR2827304B1 (fr) | 2001-07-16 | 2004-05-21 | Commissariat Energie Atomique | Procede et support d'analyse biologique utilisant des oligonucleotides comportant un marqueur activable enzymatiquement |
| DE10155055A1 (de) * | 2001-11-09 | 2003-05-28 | Friz Biochem Gmbh | Fluoreszenz-Quenchen zur Detektion von Nukleinsäure-Oligomer-Hybridisierungsereignissen bei hohen Salz-Konzentrationen |
| CN1424405A (zh) * | 2001-12-14 | 2003-06-18 | 宋克 | 基因芯片分子探针及相关技术 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925525A (en) * | 1989-06-07 | 1999-07-20 | Affymetrix, Inc. | Method of identifying nucleotide differences |
| US5538848A (en) * | 1994-11-16 | 1996-07-23 | Applied Biosystems Division, Perkin-Elmer Corp. | Method for detecting nucleic acid amplification using self-quenching fluorescence probe |
| US5578832A (en) | 1994-09-02 | 1996-11-26 | Affymetrix, Inc. | Method and apparatus for imaging a sample on a device |
| US5843655A (en) * | 1995-09-18 | 1998-12-01 | Affymetrix, Inc. | Methods for testing oligonucleotide arrays |
| US5861247A (en) * | 1996-01-26 | 1999-01-19 | University Of Chicago | Rapid method to detect duplex formation in sequencing by hybridization methods |
| US5646411A (en) | 1996-02-01 | 1997-07-08 | Molecular Dynamics, Inc. | Fluorescence imaging system compatible with macro and micro scanning objectives |
| SE522077C2 (sv) * | 1997-09-05 | 2004-01-13 | Lightup Technologies Ab | Förfarande att välja sekvens hos sond för nukleinsyrahybridisering |
| CN1268979A (zh) * | 1997-07-22 | 2000-10-04 | 拉普吉恩公司 | 阵列单元的多功能性及其用途 |
| WO1999060158A1 (en) * | 1998-05-19 | 1999-11-25 | Laboratory Of Molecular Biophotonics | Solid phase for detecting nucleic acid and method for detecting nucleic acid |
| WO2001038585A2 (en) * | 1999-11-24 | 2001-05-31 | The Regents Of The University Of California | Polymer arrays and methods of using labeled probe molecules to identify and quantify target molecule expression |
-
2000
- 2000-02-23 FR FR0002236A patent/FR2805348B1/fr not_active Expired - Fee Related
-
2001
- 2001-02-22 CA CA002399258A patent/CA2399258A1/fr not_active Abandoned
- 2001-02-22 AT AT01907873T patent/ATE275641T1/de not_active IP Right Cessation
- 2001-02-22 JP JP2001562196A patent/JP4729226B2/ja not_active Expired - Fee Related
- 2001-02-22 US US10/203,780 patent/US6861515B2/en not_active Expired - Fee Related
- 2001-02-22 EP EP03104367A patent/EP1413630B1/de not_active Expired - Lifetime
- 2001-02-22 WO PCT/FR2001/000516 patent/WO2001063282A2/fr not_active Ceased
- 2001-02-22 AU AU2001235742A patent/AU2001235742A1/en not_active Abandoned
- 2001-02-22 DE DE60105399T patent/DE60105399T2/de not_active Expired - Lifetime
- 2001-02-22 AT AT03104367T patent/ATE541050T1/de active
- 2001-02-22 EP EP01907873A patent/EP1266030B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FR2805348B1 (fr) | 2002-07-12 |
| DE60105399T2 (de) | 2005-09-15 |
| DE60105399D1 (de) | 2004-10-14 |
| AU2001235742A1 (en) | 2001-09-03 |
| CA2399258A1 (fr) | 2001-08-30 |
| US6861515B2 (en) | 2005-03-01 |
| EP1413630A1 (de) | 2004-04-28 |
| EP1266030B1 (de) | 2004-09-08 |
| US20030165914A1 (en) | 2003-09-04 |
| EP1266030A2 (de) | 2002-12-18 |
| JP4729226B2 (ja) | 2011-07-20 |
| WO2001063282A3 (fr) | 2002-04-04 |
| JP2003529751A (ja) | 2003-10-07 |
| EP1413630B1 (de) | 2012-01-11 |
| FR2805348A1 (fr) | 2001-08-24 |
| ATE275641T1 (de) | 2004-09-15 |
| WO2001063282A2 (fr) | 2001-08-30 |
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