ATE541203T1 - Messinstrument und fluorometrisches verfahren - Google Patents

Messinstrument und fluorometrisches verfahren

Info

Publication number
ATE541203T1
ATE541203T1 AT03774006T AT03774006T ATE541203T1 AT E541203 T1 ATE541203 T1 AT E541203T1 AT 03774006 T AT03774006 T AT 03774006T AT 03774006 T AT03774006 T AT 03774006T AT E541203 T1 ATE541203 T1 AT E541203T1
Authority
AT
Austria
Prior art keywords
light
mixed
measuring instrument
correction
coloring matters
Prior art date
Application number
AT03774006T
Other languages
English (en)
Inventor
Shinya Nakajima
Original Assignee
Arkray Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arkray Inc filed Critical Arkray Inc
Application granted granted Critical
Publication of ATE541203T1 publication Critical patent/ATE541203T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
    • G01N2021/6441Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks with two or more labels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6463Optics
    • G01N2021/6471Special filters, filter wheel
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N2021/6482Sample cells, cuvettes

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
AT03774006T 2002-11-14 2003-11-13 Messinstrument und fluorometrisches verfahren ATE541203T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002330787A JP3903000B2 (ja) 2002-11-14 2002-11-14 測定装置、蛍光測定装置及び蛍光測定方法
PCT/JP2003/014421 WO2004044564A1 (ja) 2002-11-14 2003-11-13 測定装置及び蛍光測定方法

Publications (1)

Publication Number Publication Date
ATE541203T1 true ATE541203T1 (de) 2012-01-15

Family

ID=32310604

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03774006T ATE541203T1 (de) 2002-11-14 2003-11-13 Messinstrument und fluorometrisches verfahren

Country Status (7)

Country Link
US (1) US7256892B2 (de)
EP (1) EP1562037B1 (de)
JP (1) JP3903000B2 (de)
CN (1) CN100498296C (de)
AT (1) ATE541203T1 (de)
AU (1) AU2003284547A1 (de)
WO (1) WO2004044564A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7426026B2 (en) 2003-10-10 2008-09-16 Hamamatsu Photonics K.K. Method and system for measuring the concentrations of fluorescent dyes
US7612871B2 (en) * 2004-09-01 2009-11-03 Honeywell International Inc Frequency-multiplexed detection of multiple wavelength light for flow cytometry
EP1988383B1 (de) 2006-02-23 2020-09-30 Nikon Corporation Spektralbildverarbeitungsverfahren, auf einem computer ausführbares spektralbildverarbeitungsprogramm und spektralabbildungssystem
US8045153B2 (en) 2006-02-23 2011-10-25 Nikon Corporation Spectral image processing method, spectral image processing program, and spectral imaging system
US7869888B2 (en) * 2006-05-31 2011-01-11 Tokyo Electron Limited Information processing apparatus, semiconductor manufacturing system, information processing method, and storage medium
JP4964568B2 (ja) * 2006-11-24 2012-07-04 浜松ホトニクス株式会社 蛍光検出装置、蛍光検出方法および蛍光検出プログラム
JP5011076B2 (ja) * 2007-11-26 2012-08-29 オリンパス株式会社 レーザ顕微鏡
JP5234943B2 (ja) * 2008-03-25 2013-07-10 一般財団法人電力中央研究所 光ファイバ複合架空地線の水検出方法および水検出装置
US20110101242A1 (en) * 2008-07-07 2011-05-05 Jason Dickens Methods, apparatus and systems employing multiple energy sources for analyzing compositions
WO2010079731A1 (ja) * 2009-01-09 2010-07-15 三井造船株式会社 蛍光検出装置及び蛍光検出方法
US8885165B2 (en) 2009-01-22 2014-11-11 Mitsui Engineering & Shipbuilding Co., Ltd. Fluorescence detecting device and fluorescence detecting method
US9778188B2 (en) * 2009-03-11 2017-10-03 Industrial Technology Research Institute Apparatus and method for detection and discrimination molecular object
WO2010143367A1 (ja) * 2009-06-12 2010-12-16 三井造船株式会社 蛍光検出装置および蛍光検出方法
JP5985140B2 (ja) 2010-04-28 2016-09-06 ソニー株式会社 蛍光強度補正方法、蛍光強度算出方法及び蛍光強度算出装置
CN102288566A (zh) * 2011-07-29 2011-12-21 肖才斌 一种便携式多功能分析仪及其测试方法
CN104246477B (zh) * 2012-03-28 2017-04-12 横河电机株式会社 物质特性测定装置
JP2014016373A (ja) * 2013-10-30 2014-01-30 Fujifilm Corp 塗布膜中の成分量の測定方法
CN110785654A (zh) * 2017-06-28 2020-02-11 文塔纳医疗系统公司 系统级校准
JP7042045B2 (ja) * 2017-08-10 2022-03-25 シスメックス株式会社 試料分析装置
CA3186952A1 (en) * 2020-07-23 2022-01-27 Jacob Freudenthal Systems and methods for biological analysis
WO2022076088A1 (en) * 2020-10-07 2022-04-14 Becton, Dickinson And Company Methods for flow cytometry panel design based on modeling and minimizing spillover spreading, and systems for practicing the same
CN114414542B (zh) * 2021-12-20 2024-01-12 成都瀚辰光翼科技有限责任公司 用于基因检测的荧光信号检测方法、装置、介质及设备

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0175352B1 (de) * 1984-09-19 1991-06-12 Siemens-Elema AB Verfahren und Anordnung zur schnellen Bestimmung der Parameter eines Probenmediums
JPH01209343A (ja) * 1988-02-16 1989-08-23 Shimadzu Corp 分光蛍光光度計
JP3207882B2 (ja) * 1991-09-13 2001-09-10 株式会社日立製作所 分光蛍光光度計のスペクトル補正方法及びスペクトル補正機能付分光蛍光光度計
JPH0921749A (ja) 1995-07-10 1997-01-21 Olympus Optical Co Ltd 多項目同時測定装置
US6015667A (en) 1996-06-03 2000-01-18 The Perkin-Emer Corporation Multicomponent analysis method including the determination of a statistical confidence interval
AU4920297A (en) * 1996-10-25 1998-05-15 Applied Imaging, Inc. Multifluor-fluorescence in situ hybridization (m-fish) imaging techniques using multiple multiband filters with image registration
AU5223899A (en) * 1998-07-27 2000-02-21 Ljl Biosystems, Inc. Apparatus and methods for spectroscopic measurements
JP2000333663A (ja) * 1999-05-25 2000-12-05 Japan Tobacco Inc 喫味用物品若しくはその部品の密度検出装置
US6362006B1 (en) * 2000-03-13 2002-03-26 General Electric Company Rapid parallel determination of non-volatile analytes in complex combinatorial samples
AU2001249237A1 (en) * 2000-03-16 2001-09-24 Spectrumedix Corporation Multi-wavelength array reader for biological assay
JP3690271B2 (ja) * 2000-11-29 2005-08-31 株式会社島津製作所 核酸の塩基配列決定のためのマトリックス値を得る方法
JP2003083894A (ja) 2001-09-14 2003-03-19 Sumitomo Electric Ind Ltd 蛍光値補正方法、蛍光値補正装置、蛍光値補正プログラム及び前記蛍光値補正プログラムを記録した記録媒体

Also Published As

Publication number Publication date
US20060108540A1 (en) 2006-05-25
CN100498296C (zh) 2009-06-10
EP1562037A1 (de) 2005-08-10
US7256892B2 (en) 2007-08-14
EP1562037B1 (de) 2012-01-11
AU2003284547A1 (en) 2004-06-03
JP3903000B2 (ja) 2007-04-11
JP2004163312A (ja) 2004-06-10
WO2004044564A1 (ja) 2004-05-27
CN1711469A (zh) 2005-12-21
EP1562037A4 (de) 2008-11-12

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