ATE541211T1 - Verfahren zur beurteilung von zellen und zellkulturen - Google Patents

Verfahren zur beurteilung von zellen und zellkulturen

Info

Publication number
ATE541211T1
ATE541211T1 AT08733105T AT08733105T ATE541211T1 AT E541211 T1 ATE541211 T1 AT E541211T1 AT 08733105 T AT08733105 T AT 08733105T AT 08733105 T AT08733105 T AT 08733105T AT E541211 T1 ATE541211 T1 AT E541211T1
Authority
AT
Austria
Prior art keywords
cell cultures
assessing cells
assessing
cells
cultures
Prior art date
Application number
AT08733105T
Other languages
English (en)
Inventor
Stephen Rapko
Stephen Duguay
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Corp filed Critical Genzyme Corp
Application granted granted Critical
Publication of ATE541211T1 publication Critical patent/ATE541211T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4722—Proteoglycans, e.g. aggreccan
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00—Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/38—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence, e.g. gluco- or galactomannans, Konjac gum, Locust bean gum or Guar gum
    • G01N2400/40—Glycosaminoglycans, i.e. GAG or mucopolysaccharides, e.g. chondroitin sulfate, dermatan sulfate, hyaluronic acid, heparin, heparan sulfate, and related sulfated polysaccharides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/10—Musculoskeletal or connective tissue disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT08733105T 2007-04-06 2008-04-03 Verfahren zur beurteilung von zellen und zellkulturen ATE541211T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91057407P 2007-04-06 2007-04-06
PCT/US2008/059275 WO2008124508A1 (en) 2007-04-06 2008-04-03 Methods of evaluating cells and cell cultures

Publications (1)

Publication Number Publication Date
ATE541211T1 true ATE541211T1 (de) 2012-01-15

Family

ID=39629001

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08733105T ATE541211T1 (de) 2007-04-06 2008-04-03 Verfahren zur beurteilung von zellen und zellkulturen

Country Status (20)

Country Link
US (3) US8029992B2 (de)
EP (2) EP2442104A3 (de)
JP (2) JP5383654B2 (de)
KR (1) KR20090127153A (de)
CN (1) CN101680881B (de)
AR (1) AR066403A1 (de)
AT (1) ATE541211T1 (de)
AU (1) AU2008237332A1 (de)
BR (1) BRPI0809902A2 (de)
CA (1) CA2682948C (de)
DK (1) DK2132562T3 (de)
ES (1) ES2380753T3 (de)
HR (1) HRP20120299T1 (de)
IL (1) IL201225A0 (de)
MX (1) MX2009010694A (de)
MY (1) MY153234A (de)
PL (1) PL2132562T3 (de)
PT (1) PT2132562E (de)
SI (1) SI2132562T1 (de)
WO (1) WO2008124508A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006007560A2 (en) 2004-07-01 2006-01-19 University Of Pennsylvania Targeted protein replacement for the treatment of lysosomal storage disorders
CA2623106C (en) 2005-09-19 2013-12-24 Histogenics Corporation Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof
JP5557084B2 (ja) * 2009-03-17 2014-07-23 独立行政法人物質・材料研究機構 組織再生方法
US20120128632A1 (en) * 2009-07-23 2012-05-24 Jeffrey Keeler Teumer Identity markers
EP2552472A4 (de) * 2010-03-29 2014-03-12 Massachusetts Inst Technology Entzündungshemmungsfaktoren
US10130736B1 (en) 2010-05-14 2018-11-20 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US8883210B1 (en) 2010-05-14 2014-11-11 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
US9352003B1 (en) 2010-05-14 2016-05-31 Musculoskeletal Transplant Foundation Tissue-derived tissuegenic implants, and methods of fabricating and using same
KR20140023260A (ko) * 2010-11-16 2014-02-26 미쓰비시 가가꾸 가부시키가이샤 Cartilage Acidic Protein 1 단백질에 의한 뇌경색의 검사 방법
KR101316702B1 (ko) * 2011-04-20 2013-10-10 서울대학교산학협력단 곤충의 표지 유전자를 이용한, 곤충의 맥주 유입 시기 계산 방법
US8834928B1 (en) 2011-05-16 2014-09-16 Musculoskeletal Transplant Foundation Tissue-derived tissugenic implants, and methods of fabricating and using same
US10350277B2 (en) 2011-09-07 2019-07-16 Icahn School Of Medicine At Mount Sinai Ceramidase and cell differentiation
ES2786128T3 (es) 2012-06-01 2020-10-08 Icahn School Med Mount Sinai Niveles de ceramida en el tratamiento y prevención de infecciones
JP6832158B2 (ja) 2013-03-14 2021-02-24 アイカーン スクール オブ メディシン アット マウント サイナイ 治療用酸性セラミダーゼ組成物ならびにそれを作製および使用する方法
US10077420B2 (en) 2014-12-02 2018-09-18 Histogenics Corporation Cell and tissue culture container
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
DE102016213684A1 (de) * 2016-07-26 2018-02-01 Tetec Tissue Engineering Technologies Ag Marker und Verfahren zur Beurteilung der Zusammensetzung oder Reinheit einer Zellkultur sowie zur in vitro Bestimmung der Identität einer Knorpelzelle oder einer Synovialzelle
AU2017403257B2 (en) * 2017-03-06 2021-09-30 Haplnscience inc. Composition for skin aging measurement, prevention, or alleviation, using HAPLN1
EP3417888A1 (de) 2017-06-25 2018-12-26 co.don AG Verfahren zum herstellen von transplantierbarem knorpelgewebe
EP3744831A1 (de) 2019-05-31 2020-12-02 co.don AG Verfahren zur kultivierung von knorpel und sphäroiden davon
CN112048563B (zh) * 2020-09-09 2022-12-02 福建华民生物科技有限公司 一种利用软骨特异性基因表达程度控制软骨质量的方法
JP7222001B2 (ja) * 2021-01-22 2023-02-14 ハプルサイエンス・インコーポレイテッド Hapln1を利用した皮膚老化の測定用または予防用または改善用の組成物
CN119235920B (zh) * 2024-12-06 2025-06-24 浙江大学 一种用于关节软骨损伤修复的mfap5阳性滑膜衬里层干细胞及其鉴定方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0920490A2 (de) 1996-07-25 1999-06-09 Genzyme Corporation Chondrozyten-medien formeln und kulturverfahren
AU3895597A (en) * 1996-07-26 1998-02-20 Genzyme Corporation Whole cell assay
WO2002085285A2 (en) * 2001-04-18 2002-10-31 Wyeth Methods and reagents for regulating bone and cartilage formation
WO2003064598A2 (en) 2002-01-25 2003-08-07 Genzyme Corporation Serum-free media for chondrocytes and methods of use thereof
WO2006094836A2 (en) * 2005-03-11 2006-09-14 Epiontis Gmbh Specific dnas for epigenetic characterisation of cells and tissues
US9234897B2 (en) * 2005-03-31 2016-01-12 Two Cells Co., Ltd Method for distinguishing mesenchymal stem cell using molecular marker and use thereof
WO2007058671A1 (en) * 2005-11-21 2007-05-24 West Michael D Novel uses of cells with prenatal patterns of gene expression
WO2007149328A1 (en) 2006-06-20 2007-12-27 Genzyme Corporation Serum-free media and their uses for chondrocyte expansion

Also Published As

Publication number Publication date
AR066403A1 (es) 2009-08-19
US8029992B2 (en) 2011-10-04
IL201225A0 (en) 2010-05-31
EP2132562B1 (de) 2012-01-11
CA2682948C (en) 2016-05-31
CN101680881B (zh) 2013-04-24
EP2132562B9 (de) 2012-05-23
PL2132562T3 (pl) 2012-06-29
US20080248481A1 (en) 2008-10-09
ES2380753T9 (es) 2012-11-27
JP2010523124A (ja) 2010-07-15
BRPI0809902A2 (pt) 2014-10-07
HK1138374A1 (en) 2010-08-20
WO2008124508A1 (en) 2008-10-16
KR20090127153A (ko) 2009-12-09
PT2132562E (pt) 2012-04-19
HRP20120299T1 (hr) 2012-04-30
EP2442104A2 (de) 2012-04-18
CA2682948A1 (en) 2008-10-16
DK2132562T3 (da) 2012-04-30
EP2132562A1 (de) 2009-12-16
JP2014036658A (ja) 2014-02-27
MX2009010694A (es) 2009-10-22
US20120149013A1 (en) 2012-06-14
US20120329051A1 (en) 2012-12-27
CN101680881A (zh) 2010-03-24
ES2380753T3 (es) 2012-05-18
SI2132562T1 (sl) 2012-05-31
AU2008237332A1 (en) 2008-10-16
MY153234A (en) 2015-01-29
JP5383654B2 (ja) 2014-01-08
EP2442104A3 (de) 2012-04-25

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