ATE542581T1 - Axialchromatographiesäulen und -verfahren - Google Patents

Axialchromatographiesäulen und -verfahren

Info

Publication number
ATE542581T1
ATE542581T1 AT07786120T AT07786120T ATE542581T1 AT E542581 T1 ATE542581 T1 AT E542581T1 AT 07786120 T AT07786120 T AT 07786120T AT 07786120 T AT07786120 T AT 07786120T AT E542581 T1 ATE542581 T1 AT E542581T1
Authority
AT
Austria
Prior art keywords
methods
chromatography columns
outlet
distribution channel
columns
Prior art date
Application number
AT07786120T
Other languages
English (en)
Inventor
Klaus Gebauer
Dan Hermansson
Henrik Svanberg
Original Assignee
Ge Healthcare Bio Sciences Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Bio Sciences Ab filed Critical Ge Healthcare Bio Sciences Ab
Application granted granted Critical
Publication of ATE542581T1 publication Critical patent/ATE542581T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/14—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the introduction of the feed to the apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/22—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the construction of the column
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/6017—Fluid distributors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/606—Construction of the column body with fluid access or exit ports
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G01N30/603—Construction of the column end pieces retaining the stationary phase, e.g. Frits

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Steroid Compounds (AREA)
AT07786120T 2006-07-19 2007-07-17 Axialchromatographiesäulen und -verfahren ATE542581T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0614316.8A GB0614316D0 (en) 2006-07-19 2006-07-19 Axial Chromatography Columns and Methods
PCT/EP2007/006320 WO2008009412A1 (en) 2006-07-19 2007-07-17 Axial chromatography columns and methods

Publications (1)

Publication Number Publication Date
ATE542581T1 true ATE542581T1 (de) 2012-02-15

Family

ID=36998322

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07786120T ATE542581T1 (de) 2006-07-19 2007-07-17 Axialchromatographiesäulen und -verfahren

Country Status (8)

Country Link
US (1) US20080017579A1 (de)
EP (1) EP2081659B1 (de)
JP (1) JP5198446B2 (de)
CN (1) CN101489637B (de)
AT (1) ATE542581T1 (de)
CA (1) CA2657720A1 (de)
GB (2) GB0614316D0 (de)
WO (1) WO2008009412A1 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9597611B2 (en) 2007-03-09 2017-03-21 Ge Healthcare Bioprocess R&D Ab Packing system and method for chromatography columns
US9597610B2 (en) 2007-03-09 2017-03-21 Ge Healthcare Bioprocess R&D Ab Packing system and method for chromatography columns
GB0704603D0 (en) * 2007-03-09 2007-04-18 Ge Healthcare Bio Sciences Ab Packing system and method for chromatography columns
GB2467207A (en) * 2009-01-26 2010-07-28 Agilent Technologies Inc Separation device with moveable filing channel
JP2012526985A (ja) * 2009-05-15 2012-11-01 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ クロマトグラフィーカラム内のフィルターホルダー
GB0922426D0 (en) * 2009-12-22 2010-02-03 Ge Healthcare Bio Sciences Ab Containers for chromatography media
EP2517000B1 (de) 2009-12-22 2015-12-16 GE Healthcare Bio-Sciences AB Verfahren zur trockenpackung von chromatographiesäulen
US11395980B2 (en) * 2010-01-25 2022-07-26 Spf Technologies Llc Chromatographic cassette
US9290372B2 (en) 2010-06-15 2016-03-22 Ge Healthcare Bio-Sciences Ab Fluid distributor unit
CN101912697B (zh) * 2010-08-13 2012-05-23 利穗科技(苏州)有限公司 一种快拆型大体积制备色谱柱
GB2485837A (en) * 2010-11-29 2012-05-30 Ge Healthcare Bio Sciences Ab Securing a distributor plate of a chromatography column by generating a vacuum
WO2012072029A1 (zh) * 2010-11-30 2012-06-07 Gu Xiongyi 一种用于生化分离过程的膨胀床色谱分离柱及工艺流程
NL2007985C2 (en) * 2010-12-16 2013-01-30 Marcellus Johannes Hubertus Raedts Disposable horizontal or radial flow type chromatographic column.
GB2491169B (en) * 2011-05-26 2014-09-10 Thermo Electron Mfg Ltd Method and apparatus for improved resolution chromatography
US10099158B2 (en) 2011-05-26 2018-10-16 Thermo Electron Manufacturing Limited Method and apparatus for improved resolution chromatography
US8685241B1 (en) 2011-12-21 2014-04-01 Sepragen Corporation Axial and radial flow columns with inflatable seals to facilitate packing and unpacking
US9327213B2 (en) 2012-02-22 2016-05-03 Bio-Rad Laboratories, Inc. Preparative chromatography column
US10092858B2 (en) 2012-05-25 2018-10-09 Thermo Electron Manufacturing Limited Method and apparatus for improved resolution chromatography
EP2864774B1 (de) * 2012-06-21 2018-04-04 GE Healthcare Bio-Sciences AB Adapter für eine chromatographiesäule
EP2864775B1 (de) * 2012-06-21 2017-02-22 GE Healthcare Bio-Sciences AB Chromatografiesäulendüse
CN102772917B (zh) * 2012-08-10 2014-12-24 黄山华绿园生物科技有限公司 一种层析柱
MY195756A (en) 2012-09-17 2023-02-09 Grace W R & Co Functionalized Particulate Support Material and Methods of Making and Using the Same
MY178616A (en) 2012-09-17 2020-10-19 Grace W R & Co Chromatography media and devices
JP6348507B2 (ja) * 2012-12-14 2018-06-27 ジーイー・ヘルスケア・バイオプロセス・アールアンドディ・アクチボラグ 充填ベッドクロマトグラフィーカラムの洗浄方法
US20150041381A1 (en) * 2013-08-07 2015-02-12 Pall Corporation Chromatography column
DE102013020400A1 (de) 2013-12-10 2015-06-11 Merck Patent Gmbh Reinigungsvorrichtung
JP6853670B2 (ja) 2014-01-16 2021-04-07 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 親和性クロマトグラフィー媒体及びクロマトグラフィーデバイス
US20150298025A1 (en) * 2014-04-17 2015-10-22 Munson Technology LLC Focused sample delivery and eluent selection for chromatography
JP6914189B2 (ja) 2014-05-02 2021-08-04 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ 官能化担体材料並びに官能化担体材料を作製及び使用する方法
FR3020964B1 (fr) * 2014-05-16 2021-11-12 Novasep Process Unite de distribution de fluide pour une colonne de chromatographie
CN107921407B (zh) 2015-06-05 2022-07-05 格雷斯公司 生物处理吸附澄清剂及其制备和使用方法
US12409440B1 (en) 2016-01-26 2025-09-09 Spf Technologies Llc Separation module
GB201701576D0 (en) * 2017-01-31 2017-03-15 Ge Healthcare Bio Sciences Ab Method and system for transferring separation resin
US11224827B2 (en) * 2016-11-11 2022-01-18 Cytiva Sweden Ab Layered chromatography column cylinder
CN115487539B (zh) * 2018-01-22 2024-02-23 普罗克西斯公司 使用大珠粒色谱介质的直接捕获
WO2020073136A1 (en) * 2018-10-11 2020-04-16 Polyanalytik Inc. Chromatography column with dual-purpose valve assembly
EP4426457A4 (de) * 2021-11-05 2025-08-20 Eczacibasi Monrol Nukleer Urunler Sanayi Ve Ticaret Anonim Sirketi Druckunterstützte trennsäule

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640813A (en) * 1969-06-09 1972-02-08 Samuel T Nerenberg Adapter for a macromolecule separation device
US4155846A (en) * 1977-10-19 1979-05-22 Bowdle Paul H Multi-segmented adsorption ion exchange or gell filtration column apparatus and process
US4389313A (en) * 1981-12-09 1983-06-21 Scientific Systems, Inc. Chromatographic column with improved seals
US4537217A (en) * 1982-12-09 1985-08-27 Research Triangle Institute Fluid distributor
US4582608A (en) * 1985-02-15 1986-04-15 Separations Technology, Inc. HPLC column
US4737292A (en) * 1986-06-05 1988-04-12 Separations Technology, Inc. HPLC column and a column packing method
US5213683A (en) * 1991-08-08 1993-05-25 Chromaflow, Inc. Apparatus for charging and discharging of chromatography column bed
US5354460A (en) * 1993-01-28 1994-10-11 The Amalgamated Sugar Company Fluid transfer system with uniform fluid distributor
US5902485A (en) * 1994-10-03 1999-05-11 Amersham Pharmacia Biotech Ab Access valve devices, their use in separation apparatus and corresponding methods
JPH11248695A (ja) * 1998-03-05 1999-09-17 Japan Nuclear Fuel Co Ltd(Jnf) イオン交換分離用カラム装置
EP1366358B1 (de) * 2001-03-09 2015-05-27 GE Healthcare Bio-Sciences AB Chromatographieeinrichtung
US6576124B2 (en) * 2001-03-09 2003-06-10 Amersham Biosciences Ab Chromatography device
GB0111485D0 (en) * 2001-05-11 2001-07-04 Amersham Pharm Biotech Ab Scalable liquid distribution system for large scale chromatography columns
US20020166816A1 (en) * 2001-05-14 2002-11-14 Allen Stephen E. Chromatography apparatus and methods
GB0116345D0 (en) * 2001-07-04 2001-08-29 Amersham Pharm Biotech Ab Chromatography column
US6736974B1 (en) * 2001-11-02 2004-05-18 Mann Welding Company Chromatography column and method of operation
US20050011835A1 (en) * 2003-07-17 2005-01-20 Sigma-Aldrich Co. High throughput flash purification stand and cartridge
US7452471B2 (en) * 2005-10-21 2008-11-18 Ge Healthcare Bio-Sciences Ab Automated packing system and method for chromatography columns

Also Published As

Publication number Publication date
EP2081659A1 (de) 2009-07-29
EP2081659B1 (de) 2012-01-25
US20080017579A1 (en) 2008-01-24
GB2440244B (en) 2009-06-10
JP5198446B2 (ja) 2013-05-15
CN101489637B (zh) 2014-11-26
CA2657720A1 (en) 2008-01-24
GB2440244A (en) 2008-01-23
JP2009544025A (ja) 2009-12-10
GB0713572D0 (en) 2007-08-22
WO2008009412A1 (en) 2008-01-24
CN101489637A (zh) 2009-07-22
GB0614316D0 (en) 2006-08-30

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