ATE54416T1 - Paramagnetische kontrastmittel fuer die anwendung in ''in vivo'' nmr-diagnostischen methoden und die herstellung davon. - Google Patents
Paramagnetische kontrastmittel fuer die anwendung in ''in vivo'' nmr-diagnostischen methoden und die herstellung davon.Info
- Publication number
- ATE54416T1 ATE54416T1 AT85307737T AT85307737T ATE54416T1 AT E54416 T1 ATE54416 T1 AT E54416T1 AT 85307737 T AT85307737 T AT 85307737T AT 85307737 T AT85307737 T AT 85307737T AT E54416 T1 ATE54416 T1 AT E54416T1
- Authority
- AT
- Austria
- Prior art keywords
- vivo
- preparation
- application
- contrast agent
- diagnostic methods
- Prior art date
Links
- 230000005298 paramagnetic effect Effects 0.000 title abstract 2
- 239000002872 contrast media Substances 0.000 title 1
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 239000002184 metal Substances 0.000 abstract 2
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002285 radioactive effect Effects 0.000 abstract 1
- 150000005846 sugar alcohols Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/126—Linear polymers, e.g. dextran, inulin, PEG
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/806—Electrical property or magnetic property
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8405499A SE465907B (sv) | 1984-11-01 | 1984-11-01 | Diagnosticeringsmedel innehaallande en paramagnetisk metall |
| EP85307737A EP0186947B1 (de) | 1984-11-01 | 1985-10-25 | Paramagnetische Kontrastmittel für die Anwendung in "in vivo" NMR-diagnostischen Methoden und die Herstellung davon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE54416T1 true ATE54416T1 (de) | 1990-07-15 |
Family
ID=20357592
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85307737T ATE54416T1 (de) | 1984-11-01 | 1985-10-25 | Paramagnetische kontrastmittel fuer die anwendung in ''in vivo'' nmr-diagnostischen methoden und die herstellung davon. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4986980A (de) |
| EP (1) | EP0186947B1 (de) |
| JP (1) | JPH0667854B2 (de) |
| AT (1) | ATE54416T1 (de) |
| DE (1) | DE3578647D1 (de) |
| DK (1) | DK167998B1 (de) |
| NO (1) | NO168928C (de) |
| SE (1) | SE465907B (de) |
Families Citing this family (103)
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| US4735796A (en) * | 1983-12-08 | 1988-04-05 | Gordon Robert T | Ferromagnetic, diamagnetic or paramagnetic particles useful in the diagnosis and treatment of disease |
| DE3324235A1 (de) * | 1983-07-01 | 1985-01-10 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue komplexbildner, komplexe und komplexsalze |
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| SE463651B (sv) * | 1983-12-21 | 1991-01-07 | Nycomed As | Diagnostikum och kontrastmedel |
| US5217998A (en) * | 1985-07-02 | 1993-06-08 | Biomedical Frontiers, Inc. | Composition for the stabilization of deferoxamine to chelate free ions in physiological fluid |
| US4795698A (en) * | 1985-10-04 | 1989-01-03 | Immunicon Corporation | Magnetic-polymer particles |
| JPH07110815B2 (ja) * | 1985-11-18 | 1995-11-29 | ボ−ド・オブ・リ−ジェンツ、ザ・ユニバ−シティ−・オブ・テキサス・システム | 画像及びスペクトル向上(およびスペクトルシフト)のためのポリキレ−ト剤 |
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| FI80801C (fi) * | 1987-01-14 | 1990-07-10 | Innofarm Oy | Konjugat av en monoklonal antikropp och anvaendning. eller ett fragment daerav och ett kelaterande aemne, dess framstaellning |
| DE3709851A1 (de) * | 1987-03-24 | 1988-10-06 | Silica Gel Gmbh Adsorptions Te | Nmr-diagnostische fluessigkeitszusammensetzungen |
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| DE3728525A1 (de) * | 1987-08-24 | 1989-03-16 | Schering Ag | Mehrkernige substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
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| EP0670167A1 (de) | 1988-08-04 | 1995-09-06 | Advanced Magnetics Incorporated | Rezeptorinduzierte endocytoseartige diagnostische Mittel |
| EP0361960A3 (de) * | 1988-09-29 | 1992-01-02 | RANNEY, David F. | Verfahren und Vorrichtung zur Bilderzeugung mittels magnetischer Resonanz |
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| US5364613A (en) * | 1989-04-07 | 1994-11-15 | Sieving Paul F | Polychelants containing macrocyclic chelant moieties |
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| GB8916781D0 (en) * | 1989-07-21 | 1989-09-06 | Nycomed As | Compositions |
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| US5393525A (en) * | 1989-07-21 | 1995-02-28 | Nycomed Imaging As | Contrast medium comprising superparamagnetic or ferromagnetic particles capable of increasing viscosity after administration |
| JP2726520B2 (ja) * | 1989-10-20 | 1998-03-11 | 名糖産業株式会社 | 有機磁性複合体 |
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| US5236694A (en) * | 1990-02-21 | 1993-08-17 | The Board Of Regents, The University Of Texas System | 19f labelled dextrans and antibodies as nmr imaging and spectroscopy agents |
| US5494655A (en) * | 1990-03-09 | 1996-02-27 | The Regents Of The University Of California | Methods for detecting blood perfusion variations by magnetic resonance imaging |
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| US4423158A (en) * | 1983-01-27 | 1983-12-27 | Gelinnovation Handelsaktiebolag | Ion adsorbent for metals having a coordination number greater than two |
| CA1242643A (en) * | 1983-08-12 | 1988-10-04 | Eric T. Fossel | Nmr imaging utilizing chemical shift reagents |
| FR2550449B1 (fr) * | 1983-08-12 | 1986-01-31 | Commissariat Energie Atomique | Agents de relaxation specifiques d'organes ou de pathologies, utilisables pour modifier les contrastes en imagerie medicale par resonance magnetique nucleaire |
| CA1243602A (en) * | 1983-08-25 | 1988-10-25 | Hong-Ning Yeung | Methods for enhancing the contrast in nmr imaging |
| US4615879A (en) * | 1983-11-14 | 1986-10-07 | Vanderbilt University | Particulate NMR contrast agents for gastrointestinal application |
| SE463651B (sv) * | 1983-12-21 | 1991-01-07 | Nycomed As | Diagnostikum och kontrastmedel |
| US4728575A (en) * | 1984-04-27 | 1988-03-01 | Vestar, Inc. | Contrast agents for NMR imaging |
| GB8413849D0 (en) * | 1984-05-31 | 1984-07-04 | Amersham Int Plc | Nmr contrast agents |
| US4675173A (en) * | 1985-05-08 | 1987-06-23 | Molecular Biosystems, Inc. | Method of magnetic resonance imaging of the liver and spleen |
| US4822594A (en) * | 1987-01-27 | 1989-04-18 | Gibby Wendell A | Contrast enhancing agents for magnetic resonance images |
-
1984
- 1984-11-01 SE SE8405499A patent/SE465907B/sv not_active IP Right Cessation
-
1985
- 1985-10-25 AT AT85307737T patent/ATE54416T1/de not_active IP Right Cessation
- 1985-10-25 EP EP85307737A patent/EP0186947B1/de not_active Expired - Lifetime
- 1985-10-25 DE DE8585307737T patent/DE3578647D1/de not_active Expired - Lifetime
- 1985-10-31 NO NO854348A patent/NO168928C/no unknown
- 1985-10-31 DK DK499985A patent/DK167998B1/da active
- 1985-11-01 JP JP60244239A patent/JPH0667854B2/ja not_active Expired - Fee Related
- 1985-11-01 US US06/793,898 patent/US4986980A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61155337A (ja) | 1986-07-15 |
| EP0186947A1 (de) | 1986-07-09 |
| DK499985A (da) | 1986-05-02 |
| US4986980A (en) | 1991-01-22 |
| DK499985D0 (da) | 1985-10-31 |
| SE465907B (sv) | 1991-11-18 |
| JPH0667854B2 (ja) | 1994-08-31 |
| DK167998B1 (da) | 1994-01-17 |
| NO168928B (no) | 1992-01-13 |
| EP0186947B1 (de) | 1990-07-11 |
| SE8405499D0 (sv) | 1984-11-01 |
| NO854348L (no) | 1986-05-02 |
| SE8405499L (sv) | 1986-05-02 |
| DE3578647D1 (de) | 1990-08-16 |
| NO168928C (no) | 1992-04-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |