ATE545408T1 - Zusammensetzungen und verfahren zur behandlung von leukämie - Google Patents
Zusammensetzungen und verfahren zur behandlung von leukämieInfo
- Publication number
- ATE545408T1 ATE545408T1 AT05783719T AT05783719T ATE545408T1 AT E545408 T1 ATE545408 T1 AT E545408T1 AT 05783719 T AT05783719 T AT 05783719T AT 05783719 T AT05783719 T AT 05783719T AT E545408 T1 ATE545408 T1 AT E545408T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- compositions
- treating leukemia
- mammal
- leukemia
- Prior art date
Links
- 208000032839 leukemia Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000024893 Acute lymphoblastic leukemia Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 229940122803 Vinca alkaloid Drugs 0.000 abstract 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 abstract 1
- 229960003957 dexamethasone Drugs 0.000 abstract 1
- 230000009826 neoplastic cell growth Effects 0.000 abstract 1
- OGWKCGZFUXNPDA-XQKSVPLYSA-N vincristine Chemical compound C([N@]1C[C@@H](C[C@]2(C(=O)OC)C=3C(=CC4=C([C@]56[C@H]([C@@]([C@H](OC(C)=O)[C@]7(CC)C=CCN([C@H]67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)C[C@@](C1)(O)CC)CC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-XQKSVPLYSA-N 0.000 abstract 1
- 229960004528 vincristine Drugs 0.000 abstract 1
- OGWKCGZFUXNPDA-UHFFFAOYSA-N vincristine Natural products C1C(CC)(O)CC(CC2(C(=O)OC)C=3C(=CC4=C(C56C(C(C(OC(C)=O)C7(CC)C=CCN(C67)CC5)(O)C(=O)OC)N4C=O)C=3)OC)CN1CCC1=C2NC2=CC=CC=C12 OGWKCGZFUXNPDA-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65148204P | 2004-08-10 | 2004-08-10 | |
| PCT/US2005/028233 WO2006020618A1 (en) | 2004-08-10 | 2005-08-09 | Compositions and methods for treating leukemia |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE545408T1 true ATE545408T1 (de) | 2012-03-15 |
Family
ID=35414880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05783719T ATE545408T1 (de) | 2004-08-10 | 2005-08-09 | Zusammensetzungen und verfahren zur behandlung von leukämie |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20090028933A1 (de) |
| EP (1) | EP1781255B1 (de) |
| JP (1) | JP5199666B2 (de) |
| AT (1) | ATE545408T1 (de) |
| AU (1) | AU2005272946B2 (de) |
| CA (1) | CA2576222C (de) |
| CY (1) | CY1112736T1 (de) |
| DK (1) | DK1781255T3 (de) |
| ES (1) | ES2382337T3 (de) |
| PT (1) | PT1781255E (de) |
| WO (1) | WO2006020618A1 (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6723338B1 (en) * | 1999-04-01 | 2004-04-20 | Inex Pharmaceuticals Corporation | Compositions and methods for treating lymphoma |
| US20120202840A1 (en) * | 2009-10-09 | 2012-08-09 | University Health Network | Use of Flubendazole and Vinca Alkaloids for Treatment of Hematological Diseases |
| WO2012076443A1 (en) * | 2010-12-08 | 2012-06-14 | F. Hoffmann-La Roche Ag | Liposomal formulation of dalcetrapib |
| MX2015005992A (es) | 2012-11-20 | 2016-03-07 | Spectrum Pharmaceuticals Inc | Metodo mejorado para la preparacion de la vincristina liposomal encapsulada para el uso terapeutico. |
| CN105960239A (zh) | 2013-11-27 | 2016-09-21 | 翁科埃斯克斯有限公司 | 利用含有噻吩并三唑并二氮杂*化合物的药物制剂治疗白血病的方法 |
| EP3137085A4 (de) * | 2014-05-02 | 2017-12-27 | Oncoethix GmbH | Verfahren zur behandlung von akuter myeloischer leukämie und/oder akuter lymphoblastischer leukämie mit thienotriazoldiazepinverbindungen |
| CN107406507A (zh) * | 2015-02-12 | 2017-11-28 | 西雅图基因公司 | 使用cd19‑adc和长春新碱的组合疗法 |
| JP6793401B2 (ja) * | 2015-03-11 | 2020-12-02 | 国立研究開発法人理化学研究所 | 難治性白血病治療薬 |
| TWI678213B (zh) | 2015-07-22 | 2019-12-01 | 美商史倍壯製藥公司 | 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物 |
| CN111658636B (zh) * | 2020-06-12 | 2021-04-13 | 桂林医学院 | 穿心莲内酯与地塞米松联用在制备复方抗急性淋巴细胞白血病药物中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4906476A (en) * | 1988-12-14 | 1990-03-06 | Liposome Technology, Inc. | Novel liposome composition for sustained release of steroidal drugs in lungs |
| US6723338B1 (en) * | 1999-04-01 | 2004-04-20 | Inex Pharmaceuticals Corporation | Compositions and methods for treating lymphoma |
| WO2000059473A1 (en) * | 1999-04-01 | 2000-10-12 | Inex Pharmaceuticals Corp. | Compositions and methods for treating lymphoma |
| US7311924B2 (en) * | 1999-04-01 | 2007-12-25 | Hana Biosciences, Inc. | Compositions and methods for treating cancer |
-
2005
- 2005-08-09 JP JP2007525727A patent/JP5199666B2/ja not_active Expired - Fee Related
- 2005-08-09 AT AT05783719T patent/ATE545408T1/de active
- 2005-08-09 ES ES05783719T patent/ES2382337T3/es not_active Expired - Lifetime
- 2005-08-09 PT PT05783719T patent/PT1781255E/pt unknown
- 2005-08-09 AU AU2005272946A patent/AU2005272946B2/en not_active Ceased
- 2005-08-09 CA CA2576222A patent/CA2576222C/en not_active Expired - Fee Related
- 2005-08-09 WO PCT/US2005/028233 patent/WO2006020618A1/en not_active Ceased
- 2005-08-09 DK DK05783719.7T patent/DK1781255T3/da active
- 2005-08-09 EP EP05783719A patent/EP1781255B1/de not_active Expired - Lifetime
-
2008
- 2008-02-11 US US12/069,488 patent/US20090028933A1/en not_active Abandoned
-
2011
- 2011-07-06 US US13/177,367 patent/US20120164211A1/en not_active Abandoned
-
2012
- 2012-05-14 CY CY20121100449T patent/CY1112736T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005272946B2 (en) | 2012-01-12 |
| US20090028933A1 (en) | 2009-01-29 |
| JP5199666B2 (ja) | 2013-05-15 |
| EP1781255B1 (de) | 2012-02-15 |
| AU2005272946A1 (en) | 2006-02-23 |
| WO2006020618A1 (en) | 2006-02-23 |
| PT1781255E (pt) | 2012-05-21 |
| CY1112736T1 (el) | 2016-02-10 |
| HK1108825A1 (en) | 2008-05-23 |
| DK1781255T3 (da) | 2012-05-29 |
| ES2382337T3 (es) | 2012-06-07 |
| CA2576222C (en) | 2014-09-30 |
| JP2008509911A (ja) | 2008-04-03 |
| CA2576222A1 (en) | 2006-02-23 |
| EP1781255A1 (de) | 2007-05-09 |
| US20120164211A1 (en) | 2012-06-28 |
| WO2006020618A8 (en) | 2006-11-02 |
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