ATE545636T1 - Synthese von cyclenderivaten - Google Patents
Synthese von cyclenderivatenInfo
- Publication number
- ATE545636T1 ATE545636T1 AT06733113T AT06733113T ATE545636T1 AT E545636 T1 ATE545636 T1 AT E545636T1 AT 06733113 T AT06733113 T AT 06733113T AT 06733113 T AT06733113 T AT 06733113T AT E545636 T1 ATE545636 T1 AT E545636T1
- Authority
- AT
- Austria
- Prior art keywords
- synthesis
- do3a
- butyl ester
- tri
- salt
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HHLZCENAOIROSL-UHFFFAOYSA-N 2-[4,7-bis(carboxymethyl)-1,4,7,10-tetrazacyclododec-1-yl]acetic acid Chemical compound OC(=O)CN1CCNCCN(CC(O)=O)CCN(CC(O)=O)CC1 HHLZCENAOIROSL-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- NMHVTLJFPDOJOD-UHFFFAOYSA-N tert-butyl 2-[4,7-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetate Chemical compound CC(C)(C)OC(=O)CN1CCNCCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 NMHVTLJFPDOJOD-UHFFFAOYSA-N 0.000 abstract 1
- 238000010626 work up procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NO20051911A NO20051911D0 (no) | 2005-04-19 | 2005-04-19 | Synthesis |
| PCT/NO2006/000141 WO2006112723A1 (en) | 2005-04-19 | 2006-04-18 | Synthesis of cyclen derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE545636T1 true ATE545636T1 (de) | 2012-03-15 |
Family
ID=35267069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06733113T ATE545636T1 (de) | 2005-04-19 | 2006-04-18 | Synthese von cyclenderivaten |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8138332B2 (de) |
| EP (1) | EP1877389B1 (de) |
| JP (1) | JP2008538371A (de) |
| KR (1) | KR20080003816A (de) |
| CN (1) | CN101160292B (de) |
| AT (1) | ATE545636T1 (de) |
| AU (1) | AU2006237745B2 (de) |
| BR (1) | BRPI0610730A2 (de) |
| CA (1) | CA2604219A1 (de) |
| ES (1) | ES2379004T3 (de) |
| MX (1) | MX2007013113A (de) |
| NO (2) | NO20051911D0 (de) |
| RU (1) | RU2405776C2 (de) |
| WO (1) | WO2006112723A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009266944A (ja) | 2008-04-23 | 2009-11-12 | Toshiba Corp | 三次元積層不揮発性半導体メモリ |
| KR101253100B1 (ko) * | 2010-02-16 | 2013-04-10 | 경북대학교 산학협력단 | 폴리아자마크로사이클릭 화합물, 그 제조 방법 및 생의학적 적용 |
| US10994016B2 (en) | 2015-09-15 | 2021-05-04 | Northwestern University | Graphene oxide mediated cellular delivery of gadolinium-labeled molecules |
| BR112018011541B1 (pt) * | 2015-12-10 | 2022-02-15 | Bracco Imaging Spa | Compostos de agentes de contraste, complexo quelado e composição farmacêutica compreendendo o referido complexo quelado |
| GB201522412D0 (en) | 2015-12-18 | 2016-02-03 | Ge Healthcare As | Dota synthesis |
| CN110835326B (zh) * | 2018-08-15 | 2023-04-14 | 正大天晴药业集团股份有限公司 | 大环螯合剂及其中间体的制备方法 |
| US12297180B2 (en) * | 2019-12-13 | 2025-05-13 | Bracco Imaging S.P.A. | Manufacturing of protected DO3A |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9320277D0 (en) * | 1993-10-01 | 1993-11-17 | Nycomed Salutar Inc | Chelants |
| GB9115375D0 (en) * | 1991-07-17 | 1991-09-04 | Salutar Inc | Compounds |
| DE60136476D1 (de) * | 2000-09-29 | 2008-12-18 | Anormed Inc | -stickstoffhaltigen zyklischen polyaminen und deren verbindungen |
| WO2005003105A1 (en) * | 2003-07-08 | 2005-01-13 | The University Of Hong Kong | Synthesis of tris n-alkylated 1,4,7,10-tetraazacyclododecanes |
-
2005
- 2005-04-19 NO NO20051911A patent/NO20051911D0/no unknown
-
2006
- 2006-04-18 AU AU2006237745A patent/AU2006237745B2/en not_active Ceased
- 2006-04-18 ES ES06733113T patent/ES2379004T3/es not_active Expired - Lifetime
- 2006-04-18 CA CA002604219A patent/CA2604219A1/en not_active Abandoned
- 2006-04-18 EP EP06733113A patent/EP1877389B1/de not_active Expired - Lifetime
- 2006-04-18 US US11/911,848 patent/US8138332B2/en not_active Expired - Fee Related
- 2006-04-18 BR BRPI0610730-3A patent/BRPI0610730A2/pt not_active IP Right Cessation
- 2006-04-18 RU RU2007137806/04A patent/RU2405776C2/ru not_active IP Right Cessation
- 2006-04-18 WO PCT/NO2006/000141 patent/WO2006112723A1/en not_active Ceased
- 2006-04-18 JP JP2008507582A patent/JP2008538371A/ja not_active Ceased
- 2006-04-18 AT AT06733113T patent/ATE545636T1/de active
- 2006-04-18 KR KR1020077023901A patent/KR20080003816A/ko not_active Abandoned
- 2006-04-18 CN CN2006800127928A patent/CN101160292B/zh not_active Expired - Fee Related
- 2006-04-18 MX MX2007013113A patent/MX2007013113A/es active IP Right Grant
-
2007
- 2007-11-13 NO NO20075829A patent/NO20075829L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20051911D0 (no) | 2005-04-19 |
| WO2006112723A1 (en) | 2006-10-26 |
| EP1877389B1 (de) | 2012-02-15 |
| JP2008538371A (ja) | 2008-10-23 |
| KR20080003816A (ko) | 2008-01-08 |
| CN101160292A (zh) | 2008-04-09 |
| US20090216011A1 (en) | 2009-08-27 |
| NO20075829L (no) | 2007-11-13 |
| AU2006237745A1 (en) | 2006-10-26 |
| US8138332B2 (en) | 2012-03-20 |
| AU2006237745B2 (en) | 2012-02-23 |
| MX2007013113A (es) | 2008-01-11 |
| BRPI0610730A2 (pt) | 2012-10-30 |
| EP1877389A1 (de) | 2008-01-16 |
| RU2007137806A (ru) | 2009-05-27 |
| ES2379004T3 (es) | 2012-04-19 |
| CN101160292B (zh) | 2010-11-03 |
| RU2405776C2 (ru) | 2010-12-10 |
| CA2604219A1 (en) | 2006-10-26 |
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